Gene 2892 (Tetrahymena)

2892

Species: Tetrahymena
Alias: 107.m00072, 3753.m00366, 2892, TTHERM_00693090, PreTt02892, 287
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
2892.AA Protein None 1076 None Fasta, JSON
2892.kin_dom Protein Kinase Domain None 92 None Fasta, JSON
2892.NA RNA None 3231 None Fasta, JSON

Protein domain

Protein domains of 2892.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 2892.AA HisKA 428-495 23 3.3e-14 54.46 SMART 1-89 (89) Show / Hide 
Range on Protein: 428-495
Range on HMM: 1-89/89
Sequence Identity: 23% (21 aa)

NKSLMLSQVSHEIRNPISCIIAMLEEIQS---------ISKNSQNQI------------YDCTQSALQSSKLLLNLLNDLLDMSQIKAG
 |. .|. .|||.|.|.. |....| .|           .. .  |.             . ......... ...|.|||||.|.| ||
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA 2892.AA HisKA 428-495 28 1.4e-13 50.32 Pfam 1-69 (69) Show / Hide 
Range on Protein: 428-495
Range on HMM: 1-69/69
Sequence Identity: 28% (20 aa)

NKSLMLSQVSHEIRNPISCIIAMLEEIQS-ISKNSQNQIYDCTQSALQSSKLLLNLLNDLLDMSQIKAG
 |. .|. .|||.|.|.. |....| .|    .... .. . ......... ...|.|||||.|.| ||
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
Kinase 2892.AA HisK 545-644 33 1.3e-38 134.65 In-house 1-142 (164) Show / Hide 
Range on Protein: 545-644
Range on HMM: 1-142/164
Sequence Identity: 33% (47 aa)

SDKYRIRQILINLISNSIKYTYGGNI----YITLTQERLD--------------------------DRYFRISVRDEGVGIKQEFRQKLFQAFGKLDD--
||. ||.|||||||||..|.|  |.|    ||..  |  .                          . ...||| | |.|...|  .|.|..||. ||  
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----TESQTKN--NPQGVGLGLMISNTIAKNLKPDQ---QN
     | .. .   |..|.||||.|.| .|| | |..   .|
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGN
Kinase 2892.AA HATPase_c 545-636 28 9.5e-22 77.93 Pfam 1-95 (120) Show / Hide 
Range on Protein: 545-636
Range on HMM: 1-95/120
Sequence Identity: 28% (29 aa)

SDKYRIRQILINLISNSIKYTYG-GNIYITLTQERLDDRYFRISVRDEGVGIKQ------EFRQKLFQAFGKLDDTESQTKNNPQG--VGLGLMISNTIA
 |  |..|.. ||..|.||.|.  | | ......     . ||.|.| |.||        | ....|..|.. |.    .  . .|   |||| |.. |.
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD---DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD--SR-RKYGGGLTGLGLYICRRIV

K
.
E
Kinase 2892.AA HATPase_c 545-656 23 8.4e-18 66.39 SMART 1-130 (130) Show / Hide 
Range on Protein: 545-656
Range on HMM: 1-130/130
Sequence Identity: 23% (34 aa)

SDKYRIRQILINLISNSIKYTYG--------------GNIYITLTQERLDDRYFRISVRDEGVGIKQ------EFRQKLFQAFGKLDDTES-----QTKN
 |  |.||.|.||..|.||.|                | | ...          ||.|.| |.|| .      | ....|..|.. || .|     ..  
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH---------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSR

NPQG--VGLGLMISNTIAKNL----KPDQQNLSQHAIFIPKNS
. .|   |||| |.. |.. .    . .    .   . .|.  
KYGGGLTGLGLSICKRIVEQHGGTIWVE----TTFTFTLPLER
Kinase 2892.AA HisK 713-727 53 0.001487 9.46 In-house 150-164 (164) Show / Hide 
Range on Protein: 713-727
Range on HMM: 150-164/164
Sequence Identity: 53% (8 aa)

EVQKGTEFYFLVYNF
|| ||..|.|..||.
EVGKGSTFSFYIYNN
REC 2892.AA REC 918-1054 16 1.3e-08 35.89 SMART 1-150 (150) Show / Hide 
Range on Protein: 918-1054
Range on HMM: 1-150/150
Sequence Identity: 16% (29 aa)

INILIADDD----QFSSFALK------IKIASAFKQFNKNLALCFTTVYSGE-------ECIRELVKTQ-----------KCYQFLFIDAQMP-------
..|||.|||    .    .|.      .   ..  ..     .  ... .||       | .. | . .           . .. ...| .||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

EIDGYESIRQIDQLNLRNNQLLEKETKEKQIFSQLQIIMCSGFQKEEAKLNIY--RIKYYLQKPVEDNQILEII
..||.| .|.|                         |||....  || .   .      |. ||......|. |
GMDGIELCRRIR-----------------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 2892.AA Response_reg 953-1055 19 3e-07 28.55 Pfam 28-115 (115) Show / Hide 
Range on Protein: 953-1055
Range on HMM: 28-115/115
Sequence Identity: 19% (21 aa)

TTVYSGEECIRELVKTQKCYQFLFIDAQMPEIDGYESIRQI-DQLNLRNNQLLEKETKEKQIFSQLQIIMCSGFQKEEAKLNIYR--IKYYLQKPVEDNQ
.....|||... . .... .  ...| .||..||.| .|.|  |.. . .               . ||||...  |. ..  ..  . .|. ||. ...
AEADDGEEALEWW-QEHH-PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ---------------TPIIMCTAHGDEDDAVEALQAGANDYITKPFDPDE

ILEIIK
....|.
LHAAIR
Response_reg 2892.AA Response_reg 920-934 33 2.702036 3.62 Pfam 1-15 (115) Show / Hide 
Range on Protein: 920-934
Range on HMM: 1-15/115
Sequence Identity: 33% (5 aa)

ILIADDDQFSSFALK
.||.||..    .|.
VLIVDDHPLMREGLR