Gene 28692 (Tetrahymena)

28692

Species: Tetrahymena
Alias: PreTt28692, 578, 3693.m00108, TTHERM_00373780, 39.m00265, 28692
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
28692.AA Protein None 1644 None Fasta, JSON
28692.kin_dom Protein Kinase Domain None 91 None Fasta, JSON
28692.NA RNA None 4935 None Fasta, JSON

Protein domain

Protein domains of 28692.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 28692.AA HisKA 1075-1141 39 3.6e-15 55.85 Pfam 1-69 (69) Show / Hide 
Range on Protein: 1075-1141
Range on HMM: 1-69/69
Sequence Identity: 39% (27 aa)

RKQIMLRNVSHELRQPLNCIISMMQLTRD--IYQDETLIQEYINPTLYSSQILLNLLNDFLDFSQIQAG
.|. .|.|.|||||.||. |. . .| .|     .|....||..  . ..| ...|.||.||||.|.||
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 28692.AA HisKA 1075-1141 28 6.1e-15 56.89 SMART 1-89 (89) Show / Hide 
Range on Protein: 1075-1141
Range on HMM: 1-89/89
Sequence Identity: 28% (25 aa)

RKQIMLRNVSHELRQPLNCIISMMQLTRD-----------IYQDETL-----------IQEYINPTLYSSQILLNLLNDFLDFSQIQAG
.|. .|.|.|||||.||. |. . .| .|             ..|..           ..||..  . ... ...|.||.||.|.|.||
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 28692.AA HisK 1190-1296 32 2.7e-48 166.75 In-house 1-153 (164) Show / Hide 
Range on Protein: 1190-1296
Range on HMM: 1-153/164
Sequence Identity: 32% (50 aa)

SDPNRIQQIITNLLGNAVKFTEQG------DILLSLEKQS--------------------------PYLYKVTVQDSGIGITEEGQKNLFKTFGK-----
||||||.||. ||..||.|||..|       | ...|...                          ..|....|||.|.|..|| ||..|| ||.     
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----VDQEFKQNLNPQGVGLGLMISNILAKQLSPS----ENLGLQVESKLDQ
      ... ....|..|.||||.|.|.|||.|.|.     | |.||.|. ..
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGK
Kinase 28692.AA HATPase_c 1190-1280 28 1.4e-19 70.36 Pfam 1-97 (120) Show / Hide 
Range on Protein: 1190-1280
Range on HMM: 1-97/120
Sequence Identity: 28% (29 aa)

SDPNRIQQIITNLLGNAVKFTEQ-GDILLSLEKQSPYLYKVTVQDSGIGITE------EGQKNLFKTFGKVDQEFKQNLNPQG--VGLGLMISNILAKQL
 ||.|..|...||..||.|.|.. | | ......      .||.|.|.||..      | . ..|  |...|.      . .|   |||| |.. ...|.
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD-SR-RKYGGGLTGLGLYICRRIVEQH
Kinase 28692.AA HATPase_c 1190-1298 21 7.6e-19 69.85 SMART 1-130 (130) Show / Hide 
Range on Protein: 1190-1298
Range on HMM: 1-130/130
Sequence Identity: 21% (31 aa)

SDPNRIQQIITNLLGNAVKFTEQ--------------GDILLSLEKQSPYLYKVTVQDSGIGITE------EGQKNLFKTFGKVDQE------FKQNLNP
 ||.|..|...|||.||.|.|..              | | ....        .||.|.|.||..      | ....|  |...|..        .. . 
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

QG--VGLGLMISNILAKQL----SPSENLGLQVESKLDQSS
.|   |||| |.. ...|.    . .      .. .|. . 
GGGLTGLGLSICKRIVEQHGGTIWVE----TTFTFTLPLER
Response_reg 28692.AA Response_reg 1596-1638 37 1.2e-08 33.52 Pfam 73-115 (115) Show / Hide 
Range on Protein: 1596-1638
Range on HMM: 73-115/115
Sequence Identity: 37% (16 aa)

PQPVIIACTGFIDEATIQKCLANGFDDYLAKPIIKDQLIEILQ
||. ||.||.. ||......|  | .||..||. .|.|.....
PQTPIIMCTAHGDEDDAVEALQAGANDYITKPFDPDELHAAIR
REC 28692.AA REC 1524-1637 16 1.3e-05 22.59 SMART 1-150 (150) Show / Hide 
Range on Protein: 1524-1637
Range on HMM: 1-150/150
Sequence Identity: 16% (26 aa)

KEVLIVDDS----DFNIYILD------KYLKTFSIE--------ADTSTNGPGSEK---KVRDKIENEK------------CE-------SCT-------
. .|||||.      .  .|       ..|.   .|        .|.  .|  . .      .......                               
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

-ACGIQTANNIQQIYESLQLPQPVIIACTGFIDEATIQKCLANGFDDYLAKPIIKDQLIEIL
   ||...  |.            ||..|.. ||......|. | |||. ||.  ..|.. .
GMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 28692.AA Response_reg 1526-1544 42 2.11649 4.0 Pfam 1-19 (115) Show / Hide 
Range on Protein: 1526-1544
Range on HMM: 1-19/115
Sequence Identity: 42% (8 aa)

VLIVDDSDFNIYILDKYLK
||||||.. .  .| ..|.
VLIVDDHPLMREGLRQILE