Gene 28479 (Tetrahymena)

28479

Species: Tetrahymena
Alias: 13.m00438, 3829.m01296, 127, TTHERM_00160870, 28479, PreTt28479
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
28479.AA Protein None 1332 None Fasta, JSON
28479.kin_dom Protein Kinase Domain None 116 None Fasta, JSON
28479.NA RNA None 3999 None Fasta, JSON

Protein domain

Protein domains of 28479.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 28479.AA HisKA 452-534 22 2.5e-07 28.5 Pfam 1-69 (69) Show / Hide 
Range on Protein: 452-534
Range on HMM: 1-69/69
Sequence Identity: 22% (19 aa)

FKNKVISSLSHELRTPLNCSIQMLELLLHSENQSVSTKTLVSQHNFQISDEVKKMFIYPALNSSYLLLSMINDIIDFAQINSG
 |.. ....||||||||.  . ..|||.    .  . ...             . ..  .....  ....|||. ||..| .|
AKRQFLANMSHELRTPLTAIRGYAELLQD--YTDLDPEQM------------RREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 28479.AA HisKA 452-534 20 2.5e-05 24.07 SMART 1-89 (89) Show / Hide 
Range on Protein: 452-534
Range on HMM: 1-89/89
Sequence Identity: 20% (20 aa)

FKNKVISSLSHELRTPLNCSIQMLELLLHSENQSVSTKTLVSQHNFQISDEVK-------------KMFIYPALNSSYLLLSMINDIIDFAQINSG
 |.. ....||||||||.  . ..|||. . ..       .  |  .  |. .             . ..  .....  ....|||. |...| .|
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYK-------QRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 28479.AA HisK 581-661 29 3.1e-32 112.87 In-house 1-120 (164) Show / Hide 
Range on Protein: 581-661
Range on HMM: 1-120/164
Sequence Identity: 29% (35 aa)

SDQNRIKQVLLALLSNAIKFTDKG------FVSITAENYQ--------------------------QDLIRISVEDTGNGITPEVKSQLFKGFQNSNS--
||.|||||.|. |.|||.|||.||      ...| .|...                          ..||.|||.||| |...| . ..|| |.| .   
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----IKSSSRQSKMSHNLG
      .. .... ..|  |
QMIKKTFNHQNKKNNQHGCG
Kinase 28479.AA HisK 737-791 40 9.9e-18 60.58 In-house 103-164 (164) Show / Hide 
Range on Protein: 737-791
Range on HMM: 103-164/164
Sequence Identity: 40% (25 aa)

QNNTNINKSSCL-SQNAGIGLTIANHLAQGLG------GNRSIIVESEINKGSSFRFFFINQ
. .| ....  . .. .|.||||.|.||.|||      |||.| |.|| .|||.| |.  |.
IKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 28479.AA HATPase_c 581-654 28 1.3e-14 53.07 Pfam 1-83 (120) Show / Hide 
Range on Protein: 581-654
Range on HMM: 1-83/120
Sequence Identity: 28% (24 aa)

SDQNRIKQVLLALLSNAIKFTDK-GFVSITAENYQQDLIRISVEDTGNGITP------EVKSQLFKGFQNSNS--IKSSSRQ--S
 |..|..||.. |..||||.| . | ......    | .||.|||.| ||.|      |. ...|  |. . .    ... .  .
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLT
Kinase 28479.AA HATPase_c 581-792 16 8.7e-13 49.72 SMART 1-130 (130) Show / Hide 
Range on Protein: 581-792
Range on HMM: 1-130/130
Sequence Identity: 16% (38 aa)

SDQNRIKQVLLALLSNAIKFTDK--------------GFVSITAENYQQDLIRISVEDTGNGITP------EVKSQLFKGFQNSNSIKSSSRQSKMSHNL
 |..|..|||. ||.||||.|..              | ......       ||.|||.| ||.|      |. ...|  |.   .  |           
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPS-----------

GKNRSLSIQTIKANLMQNASLTMKKSQQFTNQRSSQNYRSSIFGEENIEISENITRKEVNTIFAKLNSMSFGEAEEQNNTNINKSSCLSQN--AGIGLTI
                                                                                  . .|  ..    |.||.|
------------------------------------------------------------------------------RMCPDSRSRKYGGGLTGLGLSI

ANHLAQGLGGNRSIIVESEINKGSSFRFFFINQP
.. ... .||   | ||      . |.| .  ..
CKRIVEQHGGT--IWVE------TTFTFTLPLER
Kinase 28479.AA HATPase_c 753-791 35 3.6e-05 20.24 Pfam 84-120 (120) Show / Hide 
Range on Protein: 753-791
Range on HMM: 84-120/120
Sequence Identity: 35% (14 aa)

GIGLTIANHLAQGLGGNRSIIVESEINKGSSFRFFFINQ
|.||.|.. ... .||   | ||||...|. |.| .  .
GLGLYICRRIVEQHGGT--IWVESEPGGGTTFTFTLPLE
REC 28479.AA REC 1191-1316 23 5.5e-22 80.27 SMART 1-150 (150) Show / Hide 
Range on Protein: 1191-1316
Range on HMM: 1-150/150
Sequence Identity: 23% (38 aa)

NQILIVDDN----DFNLISLE------MRLLRQYHL-------KVDKANSGF-------VAINLVQKK------LTNLECCQTYKLIFMDIDMP------
  ||||||.      ..  |.      . | .. .         || | .|         |..|.|..       | .   . . ||.||| ||      
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED

-VKNGHQTTKEILSLFSSQIVKPPIISACTAYSQDAERKKAQQSGMKFYITKPIDVQQLENVL
   .| .....|             | ..||..... | .| ..|.  |||||.| ..|  ..
GGMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 28479.AA Response_reg 1193-1317 29 2.3e-15 57.59 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1193-1317
Range on HMM: 1-115/115
Sequence Identity: 29% (38 aa)

ILIVDDNDFNLISLEMRLLR-QYHL-KVDKANSGFVAINLVQKKLTNLECCQTYKLIFMDIDMPVKNGHQTTKEI-LSLF-SSQIVKPPIISACTAYSQD
.|||||.. ..  |  ..|. .. . .|. | .|  |....|..         . ||.|||.||  .| .....|   .  ..    .||| .|||....
VLIVDDHPLMREGLR-QILEQKEGYEVVAEADDGEEALEWWQEHH--------PDLIIMDINMPGMDGLELCRRIRRQHPHPQ----TPII-MCTAHGDE

AERKKAQQSGMKFYITKPIDVQQLENVLR
. . .| | |.  |||||.| ..| . .|
DDAVEALQAGANDYITKPFDPDELHAAIR