Gene 25571 (Tetrahymena)

25571

Species: Tetrahymena
Alias: TTHERM_00784670, 215, 3813.m01648, PreTt25571, 131.m00144, 25571
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
25571.AA Protein None 1800 None Fasta, JSON
25571.kin_dom Protein Kinase Domain None 175 None Fasta, JSON
25571.NA RNA None 5403 None Fasta, JSON

Protein domain

Protein domains of 25571.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 25571.AA HisKA 669-754 20 7e-06 23.45 Pfam 1-69 (69) Show / Hide 
Range on Protein: 669-754
Range on HMM: 1-69/69
Sequence Identity: 20% (19 aa)

FKEIMFANVTHDLRTPLYAIKYSIDKLKEIFQIHQCNTILEQKEQIKQKVKELQQSEVNDLHEQINISVANTHLMEAIIQDI-----IDNN
 |. ..||. |.||||| ||.  .. |..        | |  ...               ..| ...    .. |...|.|.     |...
AKRQFLANMSHELRTPLTAIRGYAELLQD-------YTDLDPEQM---------------RREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 25571.AA HisKA 669-759 20 3.3e-05 22.98 SMART 1-89 (89) Show / Hide 
Range on Protein: 669-759
Range on HMM: 1-89/89
Sequence Identity: 20% (21 aa)

FKEIMFANVTHDLRTPLYAIKYSIDKLKE-----------IFQIHQCNTILEQKEQIKQKVKELQQSEVNDLHEQINISVANTHLMEAIIQDIIDNNRNR
 |. ..||. |.||||| ||.  .. |..             .  |  . |.. |            ..   .| ...    .. |...|.|. |  | .
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRR-E------------FNCEYREYLETIQREADRMQRLINDLLDLSRIE

ME
 .
AG
Kinase 25571.AA HisK 797-971 31 1.2e-54 187.86 In-house 1-164 (164) Show / Hide 
Range on Protein: 797-971
Range on HMM: 1-164/164
Sequence Identity: 31% (64 aa)

SDSQRLKQVLMNLISNSIKFTKKG------GILIKVSKVYLKNTKNVDKYLNSPYKTNLKQKITEIVEQNDPPQNCINTSLAEKMKVLDENKLYTCYQEN
|| .|.||.|.|||||..|||.||       | |||..   .|   . || ||         |..| |.               | |  .       . .
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNN--I-KY-NS-------IFIQKIQEN---------------M-V--Q-------E-Q

VFSLGLIQFQIIDSGIGMNDKILKSLFTPYN-----------THNNENM--NRHGIGLGLTICKTIVEKLGPF-------QLKVASKEKRGSKFTFYIYH
. . .|||....|.|.||.....| .| ...           |.|..|.  |.||.|||||||. ....|||.       ...| |... ||.|.||||.
LQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQHQMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYN

D
.
N
Kinase 25571.AA HATPase_c 797-971 19 1.2e-21 77.53 Pfam 1-120 (120) Show / Hide 
Range on Protein: 797-971
Range on HMM: 1-120/120
Sequence Identity: 19% (36 aa)

SDSQRLKQVLMNLISNSIKFTKK-GGILIKVSKVYLKNTKNVDKYLNSPYKTNLKQKITEIVEQNDPPQNCINTSLAEKMKVLDENKLYTCYQENVFSLG
 |  ||.||. ||..|.||.|.. | | ..|..                                                                  .
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD----------------------------------------------------------------D

LIQFQIIDSGIGMND------KILKSLFTPYNTHNN--ENMNRHG--IGLGLTICKTIVEKLGPFQLKVASKEKRGSKFTFYIYHD
 ......|.|.|. .      . .  .| |. .  .     .. |   ||||.||. |||..|  .. | |....|..|||..  .
HVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQHG-GTIWVESEPGGGTTFTFTLPLE
Kinase 25571.AA HATPase_c 797-972 17 8.7e-18 66.34 SMART 1-130 (130) Show / Hide 
Range on Protein: 797-972
Range on HMM: 1-130/130
Sequence Identity: 17% (36 aa)

SDSQRLKQVLMNLISNSIKFTKK--------------GGILIKVSKVYLKNTKNVDKYLNSPYKTNLKQKITEIVEQNDPPQNCINTSLAEKMKVLDENK
 |  ||.||| ||..|.||.|..              | | ..|.                                                       
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------------------------------------------------------

LYTCYQENVFSLGLIQFQIIDSGIGMND------KILKSLFTPYNTHNN---------ENMNRHG--IGLGLTICKTIVEKLGPFQLKVASKEKRGSKFT
               .....|.|.|. .      .... .| |. .  .          . .. |   ||||.||| |||..|  ...|       ..||
---------------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKYGGGLTGLGLSICKRIVEQHG-GTIWVE------TTFT

FYIYHDL
|..   .
FTLPLER
REC 25571.AA REC 1658-1784 22 5.3e-27 96.94 SMART 1-150 (150) Show / Hide 
Range on Protein: 1658-1784
Range on HMM: 1-150/150
Sequence Identity: 22% (36 aa)

LNILICDDS----VFNIKVLQ-----KLLLNFKKYK------MSIDTCLSGE-------EAIEKFLQKNKPNSQEP------YNYIFLDWNMP-------
..|||.||.      . ..|.      .||    |       . .|.. .||       ||.|.. .... .....      .  |..|..||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

IMDGYETSSKIKFYVKDEQFLDCPIIICTAYEDTTEINKCLRNGTDGILTKPISQDQINELL
 |||.|.  .|.           |||..||. |   . ..|. | |. .|||...... . .
GMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 25571.AA Response_reg 1660-1785 27 1.5e-19 72.63 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1660-1785
Range on HMM: 1-115/115
Sequence Identity: 27% (35 aa)

ILICDDSVFNIKVLQKLLLNFKKYKM-SIDTCLSGEEAIEKFLQKNKPNSQEPYNYIFLDWNMPIMDGYETSSKI-KFYVKDEQFLDCPIIICTAYEDTT
.||.||.  . ..|...| .  |. . ..... .||||.|.. ..        .  |..|.||| |||.|. ..| .   ... . ..|||.|||..|  
VLIVDDHPLMREGLRQILEQ--KEGYEVVAEADDGEEALEWWQEHH-------PDLIIMDINMPGMDGLELCRRIRR---QHP-HPQTPIIMCTAHGDED

EINKCLRNGTDGILTKPISQDQINELLQ
 . ..|. | ....|||...|.. . ..
DAVEALQAGANDYITKPFDPDELHAAIR