Gene 22236 (Tetrahymena)

22236

Species: Tetrahymena
Alias: TTHERM_00216110, 22236, PreTt22236, 18.m00262, 515, 3701.m00024
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
22236.AA Protein None 1127 None Fasta, JSON
22236.kin_dom Protein Kinase Domain None 115 None Fasta, JSON
22236.NA RNA None 3384 None Fasta, JSON

Protein domain

Protein domains of 22236.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 22236.AA HisKA 402-470 19 7.4e-09 33.86 Pfam 1-69 (69) Show / Hide 
Range on Protein: 402-470
Range on HMM: 1-69/69
Sequence Identity: 19% (14 aa)

YKDKLLASVCHDIKTPVCQLIQFLNFALEKGVNKIPEDS--RNFIEISLKTTGLLMYLISDILDYSQMKKK
 | ..||.. |...||.  .. ..  ...  . . ...   | ..|. .. .  .  ||.|.||.|..   
AKRQFLANMSHELRTPLTAIRGYAELLQD--YTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 22236.AA HisKA 402-470 15 1.4e-07 32.41 SMART 1-89 (89) Show / Hide 
Range on Protein: 402-470
Range on HMM: 1-89/89
Sequence Identity: 15% (14 aa)

YKDKLLASVCHDIKTPVCQLIQFLNFALEKG-------VNKIPEDS-------------RNFIEISLKTTGLLMYLISDILDYSQMKKK
 |...||.. |...||.  .. ..  .....         . ...              | ..|. .. .  .  ||.|.||.|..   
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 22236.AA HisK 522-636 39 1.1e-56 194.61 In-house 1-164 (164) Show / Hide 
Range on Protein: 522-636
Range on HMM: 1-164/164
Sequence Identity: 39% (64 aa)

NDSNRIKQVLINLISNALKFTQQG------RIIISIS----------------TIGEN--------SNLISISVQDTGIGMSEEIKAKLFQQYS------
.| |||||.|||||||||||||.|       | |...                .| ||        .||| |||||||.||.||.. |.|....      
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----TFNQEGL--NKNGIGLGLNNCKTIVGELGPT------SQFQVESVQNEGSIFTFQIYQN
     |||..    |..|.||||. |. ... |||.       ..||.| ...||.|.|.||.|
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 22236.AA HATPase_c 522-636 28 1.2e-24 88.03 Pfam 1-120 (120) Show / Hide 
Range on Protein: 522-636
Range on HMM: 1-120/120
Sequence Identity: 28% (36 aa)

NDSNRIKQVLINLISNALKFTQQ-GRIIISISTIGENSNLISISVQDTGIGMSE------EIKAKLFQQYSTFNQ--EGLNKNG--IGLGLNNCKTIVGE
.| .|..||. ||..||.|.|.. |.| ..... .   . ..|.|.|.|.|...      |  ...|. . .. .     .  |   |||| .|. || .
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD---DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQ

LGPTSQFQVESVQNEGSIFTFQIYQN
.| |   .|||  ..|. ||| .   
HGGT--IWVESEPGGGTTFTFTLPLE
Kinase 22236.AA HATPase_c 522-637 23 2.7e-23 84.61 SMART 1-130 (130) Show / Hide 
Range on Protein: 522-637
Range on HMM: 1-130/130
Sequence Identity: 23% (35 aa)

NDSNRIKQVLINLISNALKFTQQ--------------GRIIISISTIGENSNLISISVQDTGIGMSE------EIKAKLFQQYSTFNQ---------EGL
.| .|..|||.||..||.|.|..              ||| ....         .|.|.|.|.|...      |.  ..|. . .. .            
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH---------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSR

NKNG--IGLGLNNCKTIVGELGPTSQFQVESVQNEGSIFTFQIYQNN
.  |   ||||  || || ..| | ...        . ||| .    
KYGGGLTGLGLSICKRIVEQHGGTIWVE--------TTFTFTLPLER
REC 22236.AA REC 1009-1121 21 8.5e-19 69.69 SMART 1-150 (150) Show / Hide 
Range on Protein: 1009-1121
Range on HMM: 1-150/150
Sequence Identity: 21% (34 aa)

HNILIVDDN----QFNILALK-----LLISENENII--------VYQAENGE-------QAVQKAKQM-------------NFKLIFMDMQMP-------
..||||||.    . .  .|.      .. | |..         | .| .||       .|......              .. ||.||..||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

IMDGQTASQIIKQDLKIATPIISLTANEYTNEEKKQL-TMFEDFLNKPIQKQKVHEIL
 ||| .. . |.       ||| |||.       . |     |.. ||.. . . . .
GMDGIELCRRIR-------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 22236.AA Response_reg 1011-1122 27 1e-17 66.03 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1011-1122
Range on HMM: 1-115/115
Sequence Identity: 27% (32 aa)

ILIVDDNQFNILALKLLISENENI-IVYQAENGEQAVQKAKQMNFKLIFMDMQMPIMDGQTASQIIKQDLK-IATPIISLTANEYTNEEKKQLTMF--ED
.|||||.. .  .|. .. . | . .|  |..||.|....... . ||.||..|| ||| .. . | . ..   |||| .||..   . . .       |
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHHPDLIIMDINMPGMDGLELCRRIRRQHPHPQTPIIMCTAHGD-EDDAVEALQAGAND

FLNKPIQKQKVHEILQ
.. ||. ... |....
YITKPFDPDELHAAIR