Gene 22114 (Tetrahymena)

22114

Species: Tetrahymena
Alias: 3685.m00075, 22114, 1048, 83.m00183, TTHERM_00600510, PreTt22114
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
22114.AA Protein None 1368 None Fasta, JSON
22114.kin_dom Protein Kinase Domain None 89 None Fasta, JSON
22114.NA RNA None 4107 None Fasta, JSON

Protein domain

Protein domains of 22114.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 22114.AA HisKA 887-952 23 2.8e-14 54.66 SMART 1-89 (89) Show / Hide 
Range on Protein: 887-952
Range on HMM: 1-89/89
Sequence Identity: 23% (21 aa)

YKDLMLASISHDLRTPLNFIKLMIEKCEE-----------EESLKMI------------KTILPMIKSNCELLMSLINDILDHQQMQEG
 |. .||..||.|||||. |....| ...           . . . .            . .|  |..  . . .||||.||  ....|
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA 22114.AA HisKA 887-952 30 1.1e-13 50.61 Pfam 1-69 (69) Show / Hide 
Range on Protein: 887-952
Range on HMM: 1-69/69
Sequence Identity: 30% (21 aa)

YKDLMLASISHDLRTPLNFIKLMIEKCEE--EESLKM-IKTILPMIKSNCELLMSLINDILDHQQMQEG
 |  .||..||.|||||. |....| ...  . . .  .. .|  |..  . . .||||.||  ....|
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
Kinase 22114.AA HisK 997-1085 31 1.2e-41 144.68 In-house 1-164 (164) Show / Hide 
Range on Protein: 997-1085
Range on HMM: 1-164/164
Sequence Identity: 31% (52 aa)

SDKNRLKQILINLMSNAVKFTQKG------QIKISAHLANDS-------------------------NILQLSVKDSGC---------------------
||.||.|||||||.|||.||||||      .|||.. . |.                          |..| ||.|.||                     
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----------------GVGLGLSLCRGLVSQLGPY------NKIDLASKQGKGSKFSFKIWAN
                 |.||||. |. |. .|||.      ..| . |..||||.|||.|. |
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 22114.AA HATPase_c 997-1085 25 1.5e-17 63.28 Pfam 1-120 (120) Show / Hide 
Range on Protein: 997-1085
Range on HMM: 1-120/120
Sequence Identity: 25% (32 aa)

SDKNRLKQILINLMSNAVKFTQK-GQIKISAHLANDSNILQLSVKDSGCGV------------------------------G----LGLSLCRGLVSQLG
 | .||.|.. ||..||.|.|.. |.|....|  .  . ....|.|.|.|.                              |    |||..|| .| |.|
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD--DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSRRKYGGGLTGLGLYICRRIVEQHG

PYNKIDLASKQGKGSKFSFKIWAN
   .|.. |. |.|..|.|..   
--GTIWVESEPGGGTTFTFTLPLE
Kinase 22114.AA HATPase_c 997-1086 20 2.4e-15 58.2 SMART 1-130 (130) Show / Hide 
Range on Protein: 997-1086
Range on HMM: 1-130/130
Sequence Identity: 20% (30 aa)

SDKNRLKQILINLMSNAVKFTQK--------------GQIKISAHLANDSNILQLSVKDSGC--------------------------------------
 | .||.|.|.||..||.|.|..              |.|....|        ...|.|.|.                                      
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH--------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRK

--G--VGLGLSLCRGLVSQLGPYNKIDLASKQGKGSKFSFKIWANL
  |   |||||.|. .| |.|    | .       ..|.|..   .
YGGGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER
REC 22114.AA REC 1240-1356 22 1.2e-31 112.36 SMART 1-150 (150) Show / Hide 
Range on Protein: 1240-1356
Range on HMM: 1-150/150
Sequence Identity: 22% (37 aa)

QKLLIVDDT----IFNIIALK------IWLKNFQIQ--------IDTANDGR-------EAFQKYQKT-------------QYDLILMDIQMP-------
 . |||||       .  .|.      . |.   ..        .|.| ||.       ||... |.              ..|||.|||.||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

IMDGYQSTKLIRQYESQNNLPRSLILIVSAFTSQDDVNKCINVGADDHISKPIERPIFCQIL
 |||.. .. ||            |....|... .|. ... .|||| |.||...  . . .
GMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 22114.AA Response_reg 1242-1357 31 7e-26 95.27 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1242-1357
Range on HMM: 1-115/115
Sequence Identity: 31% (38 aa)

LLIVDDTIFNIIALKIWLK-NFQI-QIDTANDGREAFQKYQKTQYDLILMDIQMPIMDGYQSTKLI-RQYESQNNLPRSLILIVSAFTSQDDVNKCINVG
.|||||   .  .|. .|.   ..  ...| ||.|| .. |. ..|||.|||.|| |||.. .. | || . . ..|   |....|. . ||. ... .|
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHHPDLIIMDINMPGMDGLELCRRIRRQHP-HPQTP---IIMCTAHGDEDDAVEALQAG

ADDHISKPIERPIFCQILK
|.|.|.||. .   .....
ANDYITKPFDPDELHAAIR