Gene 22113 (Tetrahymena)

22113

Species: Tetrahymena
Alias: 3685.m00074, 22113, 631, 83.m00182, PreTt22113, TTHERM_00600500
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
22113.AA Protein None 1839 None Fasta, JSON
22113.kin_dom Protein Kinase Domain None 120 None Fasta, JSON
22113.NA RNA None 5520 None Fasta, JSON

Protein domain

Protein domains of 22113.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 22113.AA HisKA 1221-1402 11 4.9e-05 21.5 SMART 1-89 (89) Show / Hide 
Range on Protein: 1221-1402
Range on HMM: 1-89/89
Sequence Identity: 11% (23 aa)

YKMRMFASLSHELRTPLNCSISMLEFLESDIINIMLGTSYQQFQGSQQNCIQQNNSGFGNSLYFNQNTLNASQAEESHEESSYSLYNIRHSSQLKNIQSN
 | ...|..||||||||.  . ..| |. .                                                                      
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYK-------------------------------------------------------------------

INNNNNNNNSNNNNNNNPQTTMNIFYNGSSNNSFQNFFQDIKSIQEECERVI------------QSYLKPALYSSKLLLNLINDILDFVQIDSG
                                      | . . ..  .  .            . ||. .. ... ...||||.||. .|..|
--------------------------------------QRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA 22113.AA HisKA 1221-1238 55 7.3e-05 19.94 Pfam 1-18 (69) Show / Hide 
Range on Protein: 1221-1238
Range on HMM: 1-18/69
Sequence Identity: 55% (10 aa)

YKMRMFASLSHELRTPLN
 | ...|..||||||||.
AKRQFLANMSHELRTPLT
HisKA 22113.AA HisKA 1373-1402 36 0.000235 18.17 Pfam 40-69 (69) Show / Hide 
Range on Protein: 1373-1402
Range on HMM: 40-69/69
Sequence Identity: 36% (11 aa)

QSYLKPALYSSKLLLNLINDILDFVQIDSG
. ||. .. ... ...||||.||| .|..|
REYLETIQREAQRMQRLINDLLDFSRIEAG
Kinase 22113.AA HisK 1449-1568 35 6.1e-59 202.14 In-house 1-164 (164) Show / Hide 
Range on Protein: 1449-1568
Range on HMM: 1-164/164
Sequence Identity: 35% (59 aa)

SDPNRIRQVLLNFLSNALKFTVQG------KITIQAKAVANS------------------------QNLIMLSVIDTGIGISENDIRNIFTIFNK-----
||||||.|.|.|..||||||| .|      .|.|...   .                         .|||  ||.|||.|..|... .|| .|..     
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----VDLGKNQELNSQGCGLGLTLSNSISKGLAPE----QFGGVQVESKVGQGSKFSFVIEDH
      .  .|. .|..||||||| .|.. ||| ||    ...| ||.|.||.||.|||.|...
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 22113.AA HATPase_c 1449-1568 29 7.1e-24 85.32 Pfam 1-120 (120) Show / Hide 
Range on Protein: 1449-1568
Range on HMM: 1-120/120
Sequence Identity: 29% (39 aa)

SDPNRIRQVLLNFLSNALKFTVQ-GKITIQAKAVANSQNLIMLSVIDTGIGISE------NDIRNIFTIFNKVD-LGKNQELNSQG--CGLGLTLSNSIS
 ||.|..||..|...||.|.| . |.||. ...     . . ..|.|.|.||..       || .||  | ..| .      ...|   ||||.... |.
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD---DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD--SR-RKYGGGLTGLGLYICRRIV

KGLAPEQFGG-VQVESKVGQGSKFSFVIEDH
.      .|| ..|||..|.|..|.| .   
EQ-----HGGTIWVESEPGGGTTFTFTLPLE
Kinase 22113.AA HATPase_c 1449-1569 27 5.3e-21 77.01 SMART 1-130 (130) Show / Hide 
Range on Protein: 1449-1569
Range on HMM: 1-130/130
Sequence Identity: 27% (41 aa)

SDPNRIRQVLLNFLSNALKFTVQ--------------GKITIQAKAVANSQNLIMLSVIDTGIGISE------NDIRNIFTIFNKVD------LGKNQEL
 ||.|.||||.| |.||.|.| .              |.||. ..          ..|.|.|.||..       || .||  | ..|        .... 
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH---------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSR

NSQG--CGLGLTLSNSISKGLAPEQFGG-VQVESKVGQGSKFSFVIEDHS
...|   ||||.....|.     ||.|| ..||      ..|.| .    
KYGGGLTGLGLSICKRIV-----EQHGGTIWVE------TTFTFTLPLER
REC 22113.AA REC 1700-1823 17 1.4e-14 55.7 SMART 1-150 (150) Show / Hide 
Range on Protein: 1700-1823
Range on HMM: 1-150/150
Sequence Identity: 17% (28 aa)

N---AADDN----EFNLIVIE------NILRKYHLN--------SENSCNGQ-------IAYQKILTRKQENTCCP-----HYKLIFMDIEMP-------
     .||.    . .. ...      ..|.|             .   .|.        | ... . .....  .     .. ||.|||.||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

IMNGYQTSQQIYELYQKDGALEKKPYIVACTAYVGEDDKKLAKQNFMDDFVTKPIQSNILEQVL
 |.|... ..|               |...||. .|.|.  | .  .||..|||.. . | ...
GMDGIELCRRIR-------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 22113.AA Response_reg 1702-1824 24 1.3e-09 37.02 Pfam 4-115 (115) Show / Hide 
Range on Protein: 1702-1824
Range on HMM: 4-115/115
Sequence Identity: 24% (31 aa)

ADDNEFNLIVIENILR-KYHL-NSENSCNGQIAYQKILTRKQENTCCPHYKLIFMDIEMPIMNGYQTSQQI-YELYQKDGALEKKPYIVACTAYVGEDDK
.||.. .. .. .||. |. . . .   .|. | ... ...        . ||.|||.|| |.|... ..|  ... ...     . |..|||.  |||.
VDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH--------PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ-----TPIIMCTAHGDEDDA

KLAKQNFMDDFVTKPIQSNILEQVLI
  | |  ..|..|||.  . | . . 
VEALQAGANDYITKPFDPDELHAAIR