Gene 22059 (Tetrahymena)

22059

Species: Tetrahymena
Alias: 83.m00128, 636, PreTt22059, 3685.m00020, TTHERM_00599930, 22059
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
22059.AA Protein None 1292 None Fasta, JSON
22059.kin_dom Protein Kinase Domain None 116 None Fasta, JSON
22059.NA RNA None 3879 None Fasta, JSON

Protein domain

Protein domains of 22059.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 22059.AA HisKA 543-620 20 1.5e-10 39.78 Pfam 1-69 (69) Show / Hide 
Range on Protein: 543-620
Range on HMM: 1-69/69
Sequence Identity: 20% (16 aa)

YKDDLLATVTHDLKNPLNGMVQMLDLCEK-EIINQKDITQQNQLNLEKIKEFLSIAQKNTQLLLFLVHDIQDFYQHSKR
 | ..||.. |.|..||...  ...|... .  . ...          ..|.|...|. .| .. |. |. || .    
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQM----------RREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 22059.AA HisKA 543-620 16 9.8e-09 36.26 SMART 1-89 (89) Show / Hide 
Range on Protein: 543-620
Range on HMM: 1-89/89
Sequence Identity: 16% (15 aa)

YKDDLLATVTHDLKNPLNGMVQMLDLCEK----EIINQKDITQQNQLNLEK-------IKEFLSIAQKNTQLLLFLVHDIQDFYQHSKR
 |...||.. |.|..||...  ...|...      . ...  .  |.  .        ..|.|...|. .. .. |. |. |. .    
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 22059.AA HisK 666-781 30 5.2e-52 179.11 In-house 1-164 (164) Show / Hide 
Range on Protein: 666-781
Range on HMM: 1-164/164
Sequence Identity: 30% (50 aa)

TDGFRLKQIMINLISNAIKYT------SRGGVTVSFSNTN-------------------------KQELFKISISDTGSGIPDNIKNELFKLYQ------
.|  |.|||.|||||||.|.|      ..| ....... |                         ...|..||..||| |.|.......||...      
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----TFDNKKG-ENPRGVGLGLVISQKLVQEMGPSK-----QQIQLISEKDKGTTFSFVIFLN
     ||.....  |. |.||||.|...|.. .||..     ..||..||..||.||||.|. |
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 22059.AA HATPase_c 666-781 30 8.8e-27 95.44 Pfam 1-120 (120) Show / Hide 
Range on Protein: 666-781
Range on HMM: 1-120/120
Sequence Identity: 30% (39 aa)

TDGFRLKQIMINLISNAIKYTSR-GGVTVSFSNTNKQELFKISISDTGSGIPD------NIKNELFKLYQTFDN-KKGENPRG--VGLGLVISQKLVQEM
.|  ||.|.. ||..||||.|   | .||. . ..  .   |...|.| |||.         . .|  ....|.    ..  |   |||| |....|...
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD--DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQH

GPSKQQIQLISEKDKGTTFSFVIFLN
| .   |.. || ..||||.| . | 
GGT---IWVESEPGGGTTFTFTLPLE
Kinase 22059.AA HATPase_c 666-782 24 8.6e-24 86.28 SMART 1-130 (130) Show / Hide 
Range on Protein: 666-782
Range on HMM: 1-130/130
Sequence Identity: 24% (36 aa)

TDGFRLKQIMINLISNAIKYTSR--------------GGVTVSFSNTNKQELFKISISDTGSGIPD------NIKNELFKLYQTFDN--------KKGEN
.|  ||.|...||..||||.|                | .||. .         |...|.| |||.       . . .|  ....|.         .  .
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH--------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRK

PRG--VGLGLVISQKLVQEMGPSKQQIQLISEKDKGTTFSFVIFLNL
  |   |||| |....|...| .   |..       |||.| . | .
YGGGLTGLGLSICKRIVEQHGGT---IWVE------TTFTFTLPLER
REC 22059.AA REC 1157-1265 22 1.1e-18 69.32 SMART 1-150 (150) Show / Hide 
Range on Protein: 1157-1265
Range on HMM: 1-150/150
Sequence Identity: 22% (34 aa)

KSVLIVDDEP---FNIYVMLQ----TLDFLQKNEFL--------LEKAYNGK-------EAADLVQNSP-----------NGYQLIFIDSNMP-------
...|||||.|     |  ||.      ..|.|  .          . | .|.       || .|.|. .           . ..||..| .||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

VMKGTEAIQIIK--VMISGDSRLDEIQNAQQSGADGFLSKPVKLQHIKKEI
 | | |... |.  .|... .  . .. | ..|||....||...... . |
GMDGIELCRRIRPIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 22059.AA Response_reg 1159-1266 28 1.9e-15 57.91 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1159-1266
Range on HMM: 1-115/115
Sequence Identity: 28% (34 aa)

VLIVDDEPFNIYVMLQTLDFLQKNEF-LLEKAYNGKEAADLVQNSPNGYQLIFIDSNMPVMKGTEAIQII-KV---------MISGDSRLDEIQNAQQSG
||||||.| .  .. | |..  |  .   . |..|.|| ...|.    . ||..| ||| | | |... | .          |... . .| .. | | |
VLIVDDHPLMREGLRQILEQ--KEGYEVVAEADDGEEALEWWQEHH--PDLIIMDINMPGMDGLELCRRIRRQHPHPQTPIIMCTAHGDEDDAVEALQAG

ADGFLSKPVKLQHIKKEIN
|.....||.... ....|.
ANDYITKPFDPDELHAAIR