Gene 21169 (Tetrahymena)

21169

Species: Tetrahymena
Alias: PreTt21169, 21169, TTHERM_00922900, 164.m00062, 878
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
21169.AA Protein None 1137 None Fasta, JSON
21169.kin_dom Protein Kinase Domain None 115 None Fasta, JSON
21169.NA RNA None 3414 None Fasta, JSON

Protein domain

Protein domains of 21169.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 21169.AA HisKA 414-479 30 1.9e-16 60.3 Pfam 1-69 (69) Show / Hide 
Range on Protein: 414-479
Range on HMM: 1-69/69
Sequence Identity: 30% (21 aa)

YKDELLATVSHDLKTPLNAMIQVVQTAMS--QCNNEV-YNNYFDIIDKNSKLLLNIINDILDYSQIMKG
 | ..||..||.|.|||.|..  ....     .. |  .  |...|.. .. ....|||.||.|.|  |
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 21169.AA HisKA 414-479 24 2.8e-16 61.3 SMART 1-89 (89) Show / Hide 
Range on Protein: 414-479
Range on HMM: 1-89/89
Sequence Identity: 24% (22 aa)

YKDELLATVSHDLKTPLNAMIQVVQTAMS-----------QCNNEV------------YNNYFDIIDKNSKLLLNIINDILDYSQIMKG
 |...||..||.|.|||.|..  ....              .. |             |  |...|.. .. ....|||.||.|.|  |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 21169.AA HisK 524-638 36 4.8e-59 202.49 In-house 1-164 (164) Show / Hide 
Range on Protein: 524-638
Range on HMM: 1-164/164
Sequence Identity: 36% (60 aa)

NDQNRLKQILNNIIGNALKFTFKG------YVKVQVI----------------SLPEN---------QSIQISVEDSGTGIEASLQPKLFQLYS------
.|.||.|||| |.|.||||||.||      |.|..|                 ...||         . |||||.|.| |.  ..| |.|....      
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----TFDHNKG-SNKHGVGLGLAICKKLVQLMGPQ------DSIQLISEKGKGSKFIFEIYQS
     ||.|... .|.||.||||.||..|....||.      ..||..||.||||.|.|.||. 
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 21169.AA HATPase_c 524-638 30 5.4e-28 99.65 Pfam 1-120 (120) Show / Hide 
Range on Protein: 524-638
Range on HMM: 1-120/120
Sequence Identity: 30% (38 aa)

NDQNRLKQILNNIIGNALKFTFK-GYVKVQVISLPENQSIQISVEDSGTGIEA------SLQPKLFQLYSTFDH-NKGSNKHG--VGLGLAICKKLVQLM
.|..||.|.. |...||.|.| . | ..| |   .    ..|.|||.| || .       ..|..|. . ..|     ..  |   ||||.||...|...
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD--DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQH

GPQDSIQLISEKGKGSKFIFEIYQS
| .  |.. || |.|..|.|..   
GGT--IWVESEPGGGTTFTFTLPLE
Kinase 21169.AA HATPase_c 524-639 23 1.6e-27 98.67 SMART 1-130 (130) Show / Hide 
Range on Protein: 524-639
Range on HMM: 1-130/130
Sequence Identity: 23% (35 aa)

NDQNRLKQILNNIIGNALKFTFK--------------GYVKVQVISLPENQSIQISVEDSGTGIEA------SLQPKLFQLYSTFDH--------NKGSN
.|..||.|.|.|...||.|.| .              | ..| |         .|.|||.| || .       ..|..|. . ..|         .. ..
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH--------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRK

KHG--VGLGLAICKKLVQLMGPQDSIQLISEKGKGSKFIFEIYQSL
  |   ||||.|||..|...| . ...        ..|.|..  ..
YGGGLTGLGLSICKRIVEQHGGTIWVE--------TTFTFTLPLER
REC 21169.AA REC 1000-1122 25 1.3e-28 102.34 SMART 1-150 (150) Show / Hide 
Range on Protein: 1000-1122
Range on HMM: 1-150/150
Sequence Identity: 25% (41 aa)

KRILIVDDT----PFNIRALK--IVLDNIISSSKVE--------ILQAFNGQ-------QSLEVLNNCLEEE--------KQVDLIFMDINMP-------
.|||||||     | . ..|.   |.... ..   |        . .| .|.       . || |..   ..        ...|||.|||.||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

VMDGYEATKKIREIKDFDNTKIIFATAYSEYSDLCKQNKTGGDGYLQKPIHRQDVLRIL
 |||.|....||        .||. ||... .|  .  . | |.|. ||......|  .
GMDGIELCRRIR--------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 21169.AA Response_reg 1002-1123 30 1.2e-22 83.7 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1002-1123
Range on HMM: 1-115/115
Sequence Identity: 30% (38 aa)

ILIVDDTPFNIRALKIVLDNIISSSKV-EILQAFNGQQSLEVLNNCLEEEKQVDLIFMDINMPVMDGYEATKKI-REIKDFDNTKIIFATAYSEYSDLCK
.||||| | . ..|.  |..   ..   ..  | .|.. || .     .|...|||.|||||| |||.|....| |. . ...|.||. ||... .|  .
VLIVDDHPLMREGLRQILEQ---KEGYEVVAEADDGEEALEWW-----QEHHPDLIIMDINMPGMDGLELCRRIRRQHP-HPQTPIIMCTAHGDEDDAVE

QNKTGGDGYLQKPIHRQDVLRILK
  . | ..|. ||. ... . ...
ALQAGANDYITKPFDPDELHAAIR