Gene 19671 (Tetrahymena)

19671

Species: Tetrahymena
Alias: 174.m00055, 678, TTHERM_00947510, 3678.m00020, PreTt19671, 19671
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
19671.AA Protein None 1751 None Fasta, JSON
19671.kin_dom Protein Kinase Domain None 119 None Fasta, JSON
19671.NA RNA None 5256 None Fasta, JSON

Protein domain

Protein domains of 19671.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 19671.AA HisKA 1082-1152 30 1.9e-12 46.37 Pfam 1-69 (69) Show / Hide 
Range on Protein: 1082-1152
Range on HMM: 1-69/69
Sequence Identity: 30% (22 aa)

QKMQLFGSLSHELRTPLNCSISMMEVLQNIAQSEQNHQSQLLNYIQPALNSNKLLLNMINDILDFVQLENG
.| |.. ..||||||||.  . . |.||.   .... . ..  |.. .... . ....|||.||| ..|.|
AKRQFLANMSHELRTPLTAIRGYAELLQD--YTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 19671.AA HisKA 1082-1152 24 2.2e-11 45.04 SMART 1-89 (89) Show / Hide 
Range on Protein: 1082-1152
Range on HMM: 1-89/89
Sequence Identity: 24% (22 aa)

QKMQLFGSLSHELRTPLNCSISMMEVLQN-------IAQSEQNHQSQL-----------LNYIQPALNSNKLLLNMINDILDFVQLENG
.| |.. ..||||||||.  . . |.||.       .  .. ... .|             |.. .... . ....|||.||. ..|.|
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 19671.AA HisK 1199-1317 34 3.5e-52 179.68 In-house 1-164 (164) Show / Hide 
Range on Protein: 1199-1317
Range on HMM: 1-164/164
Sequence Identity: 34% (57 aa)

SDPNRIRQVILNFLSNALKFTIAG------HIIVYAS---------------AHKGIQ----------EVTIGVKDTGIGINQENINEIFKIFNKID---
||||||.|...|..|||||||  |      .| . ..                ..  .           . | |.|||.|...|....|||.|..||   
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-------LGNNSKLNLQGCGVGLALSNSIARALGPQ----DNQGIQVQSEKNHGSNFSFVVQNQ
         .| |.| .||| ||. .|..|. |||.    .|.|||||||...|| |||...|.
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 19671.AA HATPase_c 1199-1317 31 9.5e-22 77.92 Pfam 1-120 (120) Show / Hide 
Range on Protein: 1199-1317
Range on HMM: 1-120/120
Sequence Identity: 31% (40 aa)

SDPNRIRQVILNFLSNALKFTIA-GHIIVYASAHKGIQEVTIGVKDTGIGINQ------ENINEIFKIFNKID-LGNNSKLNLQG--CGVGLALSNSIAR
 ||.|..||..|...||.|.| . ||| | ... .   .|.| |.|.|.||        |.|. ||  | . | .   .  . .|   |.||.... |..
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD--DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD--SR-RKYGGGLTGLGLYICRRIVE

ALGPQDNQGIQVQSEKNHGSNFSFVVQNQ
..| .    |.|.|| ..|. |.| .  .
QHGGT----IWVESEPGGGTTFTFTLPLE
Kinase 19671.AA HATPase_c 1199-1318 25 2e-19 71.77 SMART 1-130 (130) Show / Hide 
Range on Protein: 1199-1318
Range on HMM: 1-130/130
Sequence Identity: 25% (37 aa)

SDPNRIRQVILNFLSNALKFTIA--------------GHIIVYASAHKGIQEVTIGVKDTGIGINQ------ENINEIFKIFNKID------LGNNSKLN
 ||.|.|||..| |.||.|.| .              |.| | ..        .| |.|.|.|| .      | |. ||  | . |        ...  .
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH--------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRK

LQG--CGVGLALSNSIARALGPQDNQGIQVQSEKNHGSNFSFVVQNQN
 .|   |.||.....|....| .    |.|.      . |.| .  . 
YGGGLTGLGLSICKRIVEQHGGT----IWVE------TTFTFTLPLER
REC 19671.AA REC 1607-1734 22 3.8e-25 90.79 SMART 1-150 (150) Show / Hide 
Range on Protein: 1607-1734
Range on HMM: 1-150/150
Sequence Identity: 22% (38 aa)

PQILIVDDQ----EFNLFSLS------QLLKQFYGI-------ISDTAINFP-------QVMEKIQSKL-------NSKCCKTYRIIFMDINMP------
. ||||||     . ..  |.      .||..           . |.| .         . .|..|..         .   . . .|.|||.||      
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED

-QKSGYEVAREIKFFYNNNEILEQIKPTIIACSAYNGEEDKKKAYTHGMVDFVTKPIMKAALDAII
   .|.|..|.|.               ||...|...|||. .|. .|..|..|||.    | | |
GGMDGIELCRRIR--------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 19671.AA Response_reg 1609-1735 30 1.4e-17 65.49 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1609-1735
Range on HMM: 1-115/115
Sequence Identity: 30% (39 aa)

ILIVDDQEFNLFSLSQLLKQFYGI-ISDTAINFPQVMEKIQSKLNSKCCKTYRIIFMDINMPQKSGYEVAREI-KFFY-NNNEILEQIKPTIIACSAYNG
.||||| . ..  | |.|.| .|. . ..| . ....|..| .        . .|.||||||  .|.|..|.| .  .  .        . ||.|.|.. 
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-------PDLIIMDINMPGMDGLELCRRIRRQHPHPQ--------TPIIMCTAHGD

EEDKKKAYTHGMVDFVTKPIMKAALDAIIS
|.|. .|.  |..|..|||. ...| |.| 
EDDAVEALQAGANDYITKPFDPDELHAAIR