17211

Species: Tetrahymena
Alias: 1070, PreTt17211, 191.m00071, 3761.m00262, 17211, TTHERM_01002910
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
17211.AA Protein None 1468 None Fasta, JSON
17211.kin_dom Protein Kinase Domain None 58 None Fasta, JSON
17211.NA RNA None 4407 None Fasta, JSON

Protein domain

Protein domains of 17211.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 17211.AA HisKA 606-673 24 1.1e-09 36.76 Pfam 1-69 (69) Show / Hide
Range on Protein: 606-673
Range on HMM: 1-69/69
Sequence Identity: 24% (17 aa)

YRQKLLCSISHELRTPLNCIISMLDMLNMKNDISDANK--NYFVNPALFSSYILLNTINDILDMAEVNRS
 ....| ..||||||||. |. ....| .  .  |. .    ... .. ..  ... |||.||..     
AKRQFLANMSHELRTPLTAIRGYAELLQD-YTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG

HisKA 17211.AA HisKA 606-673 19 1.7e-08 35.45 SMART 1-89 (89) Show / Hide
Range on Protein: 606-673
Range on HMM: 1-89/89
Sequence Identity: 19% (17 aa)

YRQKLLCSISHELRTPLNCIISMLDMLNM---------KNDISDANK------------NYFVNPALFSSYILLNTINDILDMAEVNRS
 ....| ..||||||||. |. ....| .         . | ..                 ... .. ..  ... |||.||..     
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG

Kinase 17211.AA HisK 721-848 33 7.5e-40 138.72 In-house 1-150 (164) Show / Hide
Range on Protein: 721-848
Range on HMM: 1-150/164
Sequence Identity: 33% (57 aa)

TDLNKTRQVLLNLLSNALKFTQKG------NITIKLS--------------------------YSQENILQIDVSDTGCGIAPEKLKKIFFNFT------
.| |. .|.|.||.||||||||||      .|.||..                          ..|.|..||.|.|||||. .|..|||| .|       
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

QPEFDIYSNQSHHNSNQKEYLNSQLSLQFNNNNNNNNSKNAGLGLNISYILAKCLG------DNRTLNVQSE
|    .                   .  ||..| .||.. .||||.|...|||.||      .|| . ||||
Q----M------------------IKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSE

Kinase 17211.AA HATPase_c 721-778 33 1.2e-15 56.75 Pfam 1-64 (120) Show / Hide
Range on Protein: 721-778
Range on HMM: 1-64/120
Sequence Identity: 33% (22 aa)

TDLNKTRQVLLNLLSNALKFTQK-GNITIKLSYSQENILQIDVSDTGCGIAP------EKLKKIF
.| .  .||..||..||.|.|.. | ||....    . ..| |.|.|.||.|      |.. .||
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIF

Kinase 17211.AA HATPase_c 721-868 20 1.2e-11 45.91 SMART 1-130 (130) Show / Hide
Range on Protein: 721-868
Range on HMM: 1-130/130
Sequence Identity: 20% (35 aa)

TDLNKTRQVLLNLLSNALKFTQK--------------GNITIKLSYSQENILQIDVSDTGCGIAP------EKLKKIFFNFTQ----PEFDIYSNQSHHN
.| .  ||||.|||.||.|.|..              | ||....       .| |.|.|.||.|      |....||  | .    |.           
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPS-----------

SNQKEYLNSQLSLQFNNNNNNNNSKN--AGLGLNISYILAKCLGDNRTLNVQSELVSQCQNRKGCTYLPVPQLE
                ..... ...    |||| |.  ... .|    . |.            . .. .|  .
-------------RMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGT--IWVE-----------TTFTFTLPLER

REC 17211.AA REC 1337-1460 21 4e-27 97.36 SMART 1-150 (150) Show / Hide
Range on Protein: 1337-1460
Range on HMM: 1-150/150
Sequence Identity: 21% (35 aa)

PQILIVDDN----EFNIYALQ------IRLKMYSFI--------IDAATSGF-------EALDLIKKKK-------EHSCCNKYSLVFMDIDMP------
. ||||||.    . .  .|.      . |.   .         .|.| .|        |||.|.....       .    ... |..||| ||      
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED

-VMNGYQTTEKILQFYKKLKAEPPVISACSAYIQESDKQKAYQVGMKYYITKPINTQSFENVL
  |.|......|             | ...|. .|.|...|...|.  |||||.. . .  ..
GGMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI

Response_reg 17211.AA Response_reg 1339-1461 28 2.6e-24 89.65 Pfam 1-115 (115) Show / Hide
Range on Protein: 1339-1461
Range on HMM: 1-115/115
Sequence Identity: 28% (36 aa)

ILIVDDNEFNIYALQIRLK-MYSF-IIDAATSGFEALDLIKKKKEHSCCNKYSLVFMDIDMPVMNGYQTTEKI-LQFYKKLKAEPPVISACSAYIQESDK
.|||||.. .  .|.  |.  . . ....|..| |||.......       . |..|||.|| |.|......|  | . . .  .|.| .|.|. .|.|.
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-------PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ--TPII-MCTAHGDEDDA

QKAYQVGMKYYITKPINTQSFENVLA
..|.|.|. .|||||.. .   . ..
VEALQAGANDYITKPFDPDELHAAIR