Gene 17211 (Tetrahymena)
17211
Sequence
Protein domains of 17211.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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HisKA | 17211.AA | HisKA | 606-673 | 24 | 1.1e-09 | 36.76 | Pfam | 1-69 (69) | Show / Hide |
Range on Protein: 606-673 Range on HMM: 1-69/69 Sequence Identity: 24% (17 aa) YRQKLLCSISHELRTPLNCIISMLDMLNMKNDISDANK--NYFVNPALFSSYILLNTINDILDMAEVNRS ....| ..||||||||. |. ....| . . |. . ... .. .. ... |||.||.. AKRQFLANMSHELRTPLTAIRGYAELLQD-YTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG |
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HisKA | 17211.AA | HisKA | 606-673 | 19 | 1.7e-08 | 35.45 | SMART | 1-89 (89) | Show / Hide |
Range on Protein: 606-673 Range on HMM: 1-89/89 Sequence Identity: 19% (17 aa) YRQKLLCSISHELRTPLNCIISMLDMLNM---------KNDISDANK------------NYFVNPALFSSYILLNTINDILDMAEVNRS ....| ..||||||||. |. ....| . . | .. ... .. .. ... |||.||.. AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG |
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Kinase | 17211.AA | HisK | 721-848 | 33 | 7.5e-40 | 138.72 | In-house | 1-150 (164) | Show / Hide |
Range on Protein: 721-848 Range on HMM: 1-150/164 Sequence Identity: 33% (57 aa) TDLNKTRQVLLNLLSNALKFTQKG------NITIKLS--------------------------YSQENILQIDVSDTGCGIAPEKLKKIFFNFT------ .| |. .|.|.||.|||||||||| .|.||.. ..|.|..||.|.|||||. .|..|||| .| SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH QPEFDIYSNQSHHNSNQKEYLNSQLSLQFNNNNNNNNSKNAGLGLNISYILAKCLG------DNRTLNVQSE | . . ||..| .||.. .||||.|...|||.|| .|| . |||| Q----M------------------IKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSE |
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Kinase | 17211.AA | HATPase_c | 721-778 | 33 | 1.2e-15 | 56.75 | Pfam | 1-64 (120) | Show / Hide |
Range on Protein: 721-778 Range on HMM: 1-64/120 Sequence Identity: 33% (22 aa) TDLNKTRQVLLNLLSNALKFTQK-GNITIKLSYSQENILQIDVSDTGCGIAP------EKLKKIF .| . .||..||..||.|.|.. | ||.... . ..| |.|.|.||.| |.. .|| GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIF |
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Kinase | 17211.AA | HATPase_c | 721-868 | 20 | 1.2e-11 | 45.91 | SMART | 1-130 (130) | Show / Hide |
Range on Protein: 721-868 Range on HMM: 1-130/130 Sequence Identity: 20% (35 aa) TDLNKTRQVLLNLLSNALKFTQK--------------GNITIKLSYSQENILQIDVSDTGCGIAP------EKLKKIFFNFTQ----PEFDIYSNQSHHN .| . ||||.|||.||.|.|.. | ||.... .| |.|.|.||.| |....|| | . |. GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPS----------- SNQKEYLNSQLSLQFNNNNNNNNSKN--AGLGLNISYILAKCLGDNRTLNVQSELVSQCQNRKGCTYLPVPQLE ..... ... |||| |. ... .| . |. . .. .| . -------------RMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGT--IWVE-----------TTFTFTLPLER |
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REC | 17211.AA | REC | 1337-1460 | 21 | 4e-27 | 97.36 | SMART | 1-150 (150) | Show / Hide |
Range on Protein: 1337-1460 Range on HMM: 1-150/150 Sequence Identity: 21% (35 aa) PQILIVDDN----EFNIYALQ------IRLKMYSFI--------IDAATSGF-------EALDLIKKKK-------EHSCCNKYSLVFMDIDMP------ . ||||||. . . .|. . |. . .|.| .| |||.|..... . ... |..||| || MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED -VMNGYQTTEKILQFYKKLKAEPPVISACSAYIQESDKQKAYQVGMKYYITKPINTQSFENVL |.|......| | ...|. .|.|...|...|. |||||.. . . .. GGMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI |
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Response_reg | 17211.AA | Response_reg | 1339-1461 | 28 | 2.6e-24 | 89.65 | Pfam | 1-115 (115) | Show / Hide |
Range on Protein: 1339-1461 Range on HMM: 1-115/115 Sequence Identity: 28% (36 aa) ILIVDDNEFNIYALQIRLK-MYSF-IIDAATSGFEALDLIKKKKEHSCCNKYSLVFMDIDMPVMNGYQTTEKI-LQFYKKLKAEPPVISACSAYIQESDK .|||||.. . .|. |. . . ....|..| |||....... . |..|||.|| |.|......| | . . . .|.| .|.|. .|.|. VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-------PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ--TPII-MCTAHGDEDDA QKAYQVGMKYYITKPINTQSFENVLA ..|.|.|. .|||||.. . . .. VEALQAGANDYITKPFDPDELHAAIR |