17204

Species: Tetrahymena
Alias: PreTt17204, TTHERM_01002840, 17204, 273, 191.m00064, 3761.m00256
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
17204.AA Protein None 2687 None Fasta, JSON
17204.kin_dom Protein Kinase Domain None 117 None Fasta, JSON
17204.NA RNA None 8064 None Fasta, JSON

Protein domain

Protein domains of 17204.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 17204.AA HisKA 853-920 24 2.7e-08 31.88 Pfam 1-69 (69) Show / Hide
Range on Protein: 853-920
Range on HMM: 1-69/69
Sequence Identity: 24% (17 aa)

YKNKILSSITHELKTPLNCSIQMLDMLLQNDDISDVL-KQIFIIPALNSNHLLLNIINDILDLAQINYG
 |.. |... |||.|||.  . ....|.  .| ..    . ..  .... . ....|||.||...|  |
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG

HisKA 17204.AA HisKA 853-920 20 3.2e-07 31.23 SMART 1-89 (89) Show / Hide
Range on Protein: 853-920
Range on HMM: 1-89/89
Sequence Identity: 20% (18 aa)

YKNKILSSITHELKTPLNCSIQMLDMLLQN---------DDISDVLK------------QIFIIPALNSNHLLLNIINDILDLAQINYG
 |.. |... |||.|||.  . ....|. .         .| ..               . ..  .... . ....|||.|||..|  |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG

Kinase 17204.AA HisK 967-1083 40 6.8e-59 201.98 In-house 1-164 (164) Show / Hide
Range on Protein: 967-1083
Range on HMM: 1-164/164
Sequence Identity: 40% (67 aa)

SDQSRIRQVLLNLLSNALKFTQNG------KITIRTHLIE--------------------------DNLIQVDIEDTGCGIPEKNLNKIIGRFGKKDHQ-
||..||.|.|.||.||||||||.|      .|.|   .|.                          .||||....|||||.||....||   ||..|.| 
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-------NINHQ-LNTFGGGLGLTIANNLATGLG------GNRRLQVQSIENVGSKFSFCIVNQ
       | ... .|. | ||||||.||||.|||      ||| .|||| ...||.|||.| |.
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN

Kinase 17204.AA HATPase_c 967-1083 29 2.8e-25 90.22 Pfam 1-120 (120) Show / Hide
Range on Protein: 967-1083
Range on HMM: 1-120/120
Sequence Identity: 29% (38 aa)

SDQSRIRQVLLNLLSNALKFTQN-GKITIRTHLIEDNLIQVDIEDTGCGIPE------KNLNKIIGRFGKKDHQNINHQLNTFGG---GLGLTIANNLAT
 |. |..||..||..||.|.|.  |.||.| |  . . ... .||.|.|||.      .....|  .|.. | .   .    .||   ||||.|.. .. 
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD---SR-RKYGGGLTGLGLYICRRIVE

GLGGNRRLQVQSIENVGSKFSFCIVNQ
 .||   ..|.| .. |..|.| .  .
QHGGT--IWVESEPGGGTTFTFTLPLE

Kinase 17204.AA HATPase_c 967-1084 26 1.2e-22 82.52 SMART 1-130 (130) Show / Hide
Range on Protein: 967-1084
Range on HMM: 1-130/130
Sequence Identity: 26% (39 aa)

SDQSRIRQVLLNLLSNALKFTQN--------------GKITIRTHLIEDNLIQVDIEDTGCGIPE------KNLNKIIGRFGKKDH----QNINHQLNTF
 |. |.||||.|||.||.|.|.               |.||.| |       .. .||.|.|||.      . ...|  .|.. |        . .    
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

GG---GLGLTIANNLATGLGGNRRLQVQSIENVGSKFSFCIVNQP
||   ||||.|.....  .||   ..|.      ..|.| .  ..
GGGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER

REC 17204.AA REC 1722-1847 21 1.9e-22 81.79 SMART 1-150 (150) Show / Hide
Range on Protein: 1722-1847
Range on HMM: 1-150/150
Sequence Identity: 21% (36 aa)

SNILIVDDN----EFNIYTLE------IRLKMYGFI--------TDRATSGM-------AAIQLVRNK------LEINTCCNLYLLIFMDIDMP------
 .||||||.    . .  .|.      . |.  |.          | | .|        .|..|....        ..   . . ||.||| ||      
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED

-VKNGYETTSEILQCYKEKKIQKPPPISACTAYVQQSEKAKAIQSGMQFYITKPINQGLLEDTL
   .|.|.. .|             || ..||. . . . .|...|.  |||||...  | ...
GGMDGIELCRRIR------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI

Response_reg 17204.AA Response_reg 1724-1848 28 9.3e-16 59.01 Pfam 1-115 (115) Show / Hide
Range on Protein: 1724-1848
Range on HMM: 1-115/115
Sequence Identity: 28% (36 aa)

ILIVDDNEFNIYTLEIRLK-MYGF-ITDRATSGMAAIQLVRNKLEINTCCNLYLLIFMDIDMPVKNGYETTSEI-LQCYKEKKIQKPPPISACTAYVQQS
.|||||.. .   |   |.  .|. ... |..| .|.......         . ||.|||.||  .|.|....|  | . . .    .|| .|||. . .
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH--------PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ----TPIIMCTAHGDED

EKAKAIQSGMQFYITKPINQGLLEDTLL
 . .|.| |.  |||||...  | . . 
DAVEALQAGANDYITKPFDPDELHAAIR