17203

Species: Tetrahymena
Alias: 17203, PreTt17203, 274, 3761.m00255, TTHERM_01002830, 191.m00063
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
17203.AA Protein None 1688 None Fasta, JSON
17203.kin_dom Protein Kinase Domain None 117 None Fasta, JSON
17203.NA RNA None 5067 None Fasta, JSON

Protein domain

Protein domains of 17203.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 17203.AA HisKA 779-846 28 3.4e-08 31.53 Pfam 1-69 (69) Show / Hide
Range on Protein: 779-846
Range on HMM: 1-69/69
Sequence Identity: 28% (20 aa)

YKNKILSSVSHELRTPLNCSIQLLDLLSQSEEISDIT-KNAFVNPAMYSNFLMLNIINDILDLAQINYG
 |.. |...||||||||.  . ...||  ... .. .    ... .  .   |...|||.||...|  |
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG

HisKA 17203.AA HisKA 779-846 23 2.8e-07 31.43 SMART 1-89 (89) Show / Hide
Range on Protein: 779-846
Range on HMM: 1-89/89
Sequence Identity: 23% (21 aa)

YKNKILSSVSHELRTPLNCSIQLLDLLSQ---------SEEISDITK------------NAFVNPAMYSNFLMLNIINDILDLAQINYG
 |.. |...||||||||.  . ...||           . . .. .               ... .  .   |...|||.|||..|  |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG

Kinase 17203.AA HisK 893-1009 39 1.6e-56 194.07 In-house 1-164 (164) Show / Hide
Range on Protein: 893-1009
Range on HMM: 1-164/164
Sequence Identity: 39% (65 aa)

SDANRIRQVLLNLLNNALKFTQHG------SISVKAN--------------------------LVEPNLIQIDVEDTGCGIKKKDLNKILGQFQYQDE--
|| |||.|.|.||. |||||||.|      .|..|..                          |...|||||.|.|||||.......||  .|...|.  
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-------LEKSKSTNSLNGGLGLTIANNLATGLG------GNRRIKVRSEYKAGSIFSFYIVNH
        ...|. |.   ||||||.||||.|||      ||| |.| ||.. ||.||||| |.
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN

Kinase 17203.AA HATPase_c 893-1009 30 2.7e-25 90.27 Pfam 1-120 (120) Show / Hide
Range on Protein: 893-1009
Range on HMM: 1-120/120
Sequence Identity: 30% (39 aa)

SDANRIRQVLLNLLNNALKFTQH-GSISVKANLVEPNLIQIDVEDTGCGIKK------KDLNKILGQFQYQDELEKSKSTNSLN--GGLGLTIANNLATG
 |..|..||..||. ||.|.|.  | |.|..   . . ..| |||.|.|| .      .|...|.  |.  |..  |   ..     ||||.|.. ..  
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD--SR-RKYGGGLTGLGLYICRRIVEQ

LGGNRRIKVRSEYKAGSIFSFYIVNH
.||   | |.|| . |. |.|..   
HGGT--IWVESEPGGGTTFTFTLPLE

Kinase 17203.AA HATPase_c 893-1010 27 5e-24 87.06 SMART 1-130 (130) Show / Hide
Range on Protein: 893-1010
Range on HMM: 1-130/130
Sequence Identity: 27% (40 aa)

SDANRIRQVLLNLLNNALKFTQH--------------GSISVKANLVEPNLIQIDVEDTGCGIKK------KDLNKILGQFQYQDE-----LEKSKSTNS
 |..|.||||.|||.||.|.|..              | |.|...       .| |||.|.|| .      .|...|.  |.  |.      ..|.|...
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

LN--GGLGLTIANNLATGLGGNRRIKVRSEYKAGSIFSFYIVNHG
     ||||.|.....  .||   |.|.      . |.|..    
GGGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER

REC 17203.AA REC 1551-1676 26 5e-26 93.72 SMART 1-150 (150) Show / Hide
Range on Protein: 1551-1676
Range on HMM: 1-150/150
Sequence Identity: 26% (43 aa)

SNILIVDDE----GFNLYALE------LKLKFYGFI--------VDKAPGGI-------EALEFVQKK--FESDACHK---KYDIILMDINMP-------
 .||||||.      .. .|.      . |.  |.         || |  |        |||| .|..  ...||      ..|.|.|||.||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

IKNGYEATEDILKYFKSKNVNQPTQISACSAYIQEEMKKKAKECGMKYYITKPVNQQQLETVL
  .|.|... |              | ...|. .||.. .| | |.  |||||.....|  ..
GMDGIELCRRIR------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI

Response_reg 17203.AA Response_reg 1553-1677 31 1.5e-20 76.15 Pfam 1-115 (115) Show / Hide
Range on Protein: 1553-1677
Range on HMM: 1-115/115
Sequence Identity: 31% (40 aa)

ILIVDDEGFNLYALELKLK-FYGF-IVDKAPGGIEALEFVQKKFESDACHKKYDIILMDINMPIKNGYEATEDI-LKYFKSKNVNQPTQISACSAYIQEE
.|||||.  .. .|   |.  .|. .|. |. | |||| .|..         .|.|.||||||  .|.|... |  .   . .    | | .|.|. .|.
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH--------PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ----TPIIMCTAHGDED

MKKKAKECGMKYYITKPVNQQQLETVLK
.. .| . |. .|||||.....| . ..
DAVEALQAGANDYITKPFDPDELHAAIR