Gene 17203 (Tetrahymena)
17203
Sequence
Protein domains of 17203.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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HisKA | 17203.AA | HisKA | 779-846 | 28 | 3.4e-08 | 31.53 | Pfam | 1-69 (69) | Show / Hide |
Range on Protein: 779-846 Range on HMM: 1-69/69 Sequence Identity: 28% (20 aa) YKNKILSSVSHELRTPLNCSIQLLDLLSQSEEISDIT-KNAFVNPAMYSNFLMLNIINDILDLAQINYG |.. |...||||||||. . ...|| ... .. . ... . . |...|||.||...| | AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG |
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HisKA | 17203.AA | HisKA | 779-846 | 23 | 2.8e-07 | 31.43 | SMART | 1-89 (89) | Show / Hide |
Range on Protein: 779-846 Range on HMM: 1-89/89 Sequence Identity: 23% (21 aa) YKNKILSSVSHELRTPLNCSIQLLDLLSQ---------SEEISDITK------------NAFVNPAMYSNFLMLNIINDILDLAQINYG |.. |...||||||||. . ...|| . . .. . ... . . |...|||.|||..| | AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG |
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Kinase | 17203.AA | HisK | 893-1009 | 39 | 1.6e-56 | 194.07 | In-house | 1-164 (164) | Show / Hide |
Range on Protein: 893-1009 Range on HMM: 1-164/164 Sequence Identity: 39% (65 aa) SDANRIRQVLLNLLNNALKFTQHG------SISVKAN--------------------------LVEPNLIQIDVEDTGCGIKKKDLNKILGQFQYQDE-- || |||.|.|.||. |||||||.| .|..|.. |...|||||.|.|||||.......|| .|...|. SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH -------LEKSKSTNSLNGGLGLTIANNLATGLG------GNRRIKVRSEYKAGSIFSFYIVNH ...|. |. ||||||.||||.||| ||| |.| ||.. ||.||||| |. QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN |
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Kinase | 17203.AA | HATPase_c | 893-1009 | 30 | 2.7e-25 | 90.27 | Pfam | 1-120 (120) | Show / Hide |
Range on Protein: 893-1009 Range on HMM: 1-120/120 Sequence Identity: 30% (39 aa) SDANRIRQVLLNLLNNALKFTQH-GSISVKANLVEPNLIQIDVEDTGCGIKK------KDLNKILGQFQYQDELEKSKSTNSLN--GGLGLTIANNLATG |..|..||..||. ||.|.|. | |.|.. . . ..| |||.|.|| . .|...|. |. |.. | .. ||||.|.. .. GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD--SR-RKYGGGLTGLGLYICRRIVEQ LGGNRRIKVRSEYKAGSIFSFYIVNH .|| | |.|| . |. |.|.. HGGT--IWVESEPGGGTTFTFTLPLE |
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Kinase | 17203.AA | HATPase_c | 893-1010 | 27 | 5e-24 | 87.06 | SMART | 1-130 (130) | Show / Hide |
Range on Protein: 893-1010 Range on HMM: 1-130/130 Sequence Identity: 27% (40 aa) SDANRIRQVLLNLLNNALKFTQH--------------GSISVKANLVEPNLIQIDVEDTGCGIKK------KDLNKILGQFQYQDE-----LEKSKSTNS |..|.||||.|||.||.|.|.. | |.|... .| |||.|.|| . .|...|. |. |. ..|.|... GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY LN--GGLGLTIANNLATGLGGNRRIKVRSEYKAGSIFSFYIVNHG ||||.|..... .|| |.|. . |.|.. GGGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER |
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REC | 17203.AA | REC | 1551-1676 | 26 | 5e-26 | 93.72 | SMART | 1-150 (150) | Show / Hide |
Range on Protein: 1551-1676 Range on HMM: 1-150/150 Sequence Identity: 26% (43 aa) SNILIVDDE----GFNLYALE------LKLKFYGFI--------VDKAPGGI-------EALEFVQKK--FESDACHK---KYDIILMDINMP------- .||||||. .. .|. . |. |. || | | |||| .|.. ...|| ..|.|.|||.|| MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG IKNGYEATEDILKYFKSKNVNQPTQISACSAYIQEEMKKKAKECGMKYYITKPVNQQQLETVL .|.|... | | ...|. .||.. .| | |. |||||.....| .. GMDGIELCRRIR------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI |
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Response_reg | 17203.AA | Response_reg | 1553-1677 | 31 | 1.5e-20 | 76.15 | Pfam | 1-115 (115) | Show / Hide |
Range on Protein: 1553-1677 Range on HMM: 1-115/115 Sequence Identity: 31% (40 aa) ILIVDDEGFNLYALELKLK-FYGF-IVDKAPGGIEALEFVQKKFESDACHKKYDIILMDINMPIKNGYEATEDI-LKYFKSKNVNQPTQISACSAYIQEE .|||||. .. .| |. .|. .|. |. | |||| .|.. .|.|.|||||| .|.|... | . . . | | .|.|. .|. VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH--------PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ----TPIIMCTAHGDED MKKKAKECGMKYYITKPVNQQQLETVLK .. .| . |. .|||||.....| . .. DAVEALQAGANDYITKPFDPDELHAAIR |