Gene 16839 (Tetrahymena)

16839

Species: Tetrahymena
Alias: 112.m00083, 921, PreTt16839, TTHERM_00711790, 16839
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
16839.AA Protein None 1755 None Fasta, JSON
16839.kin_dom Protein Kinase Domain None 116 None Fasta, JSON
16839.NA RNA None 5268 None Fasta, JSON

Protein domain

Protein domains of 16839.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 16839.AA HisKA 507-572 22 2.5e-11 44.87 SMART 1-89 (89) Show / Hide 
Range on Protein: 507-572
Range on HMM: 1-89/89
Sequence Identity: 22% (20 aa)

YKNELLATVTHDLKTPLNGMLSILEVAQE------------LTDIH-----------EIKNLIQIVHKNGILLNFLIMDILDYSAIIKG
 |...||.. |.|.|||....  .|..|.            |.. .           |.. ....... .  .. || |.||.| |  |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA 16839.AA HisKA 507-572 27 2.5e-11 42.47 Pfam 1-69 (69) Show / Hide 
Range on Protein: 507-572
Range on HMM: 1-69/69
Sequence Identity: 27% (19 aa)

YKNELLATVTHDLKTPLNGMLSILEVAQE---LTDIHEIKNLIQIVHKNGILLNFLIMDILDYSAIIKG
 |...||.. |.|.|||....  .|..|.   |.. .... ....... .  .. || |.||.| |  |
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
Kinase 16839.AA HisK 620-735 35 1.2e-56 194.56 In-house 1-164 (164) Show / Hide 
Range on Protein: 620-735
Range on HMM: 1-164/164
Sequence Identity: 35% (58 aa)

NDGRRIKQILLNLTSNALKFT------FVGEIVIVIK---------------KEILTD---------DLIKITVKDTGVGIPDTLKPKLFKLYG------
.| .||||||.|| |||||||      | | | | ..               ..| ..         .||.|.|.|||.|.|. .. |.||..|      
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----TYDHNNG-SNKHGVGLGLVITKKLASQVGPK------DSLRFQSKEKIGTEFSFHIYRN
     |..|.|. .|.||.||||.| ..|| ..||.      ... .||....|..|||.|| |
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 16839.AA HATPase_c 620-735 28 1.3e-24 87.9 Pfam 1-120 (120) Show / Hide 
Range on Protein: 620-735
Range on HMM: 1-120/120
Sequence Identity: 28% (36 aa)

NDGRRIKQILLNLTSNALKFTFV-GEIVIVIKKEILTDDLIKITVKDTGVGIPD------TLKPKLFKLYGTYDH-NNGSNKHG--VGLGLVITKKLASQ
.| .|..|...|| .||.|.|   |.| . ....    | . |||.|.|.|||.       . |..|  ....|   . ..  |   |||| | .... |
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD---DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQ

VGPKDSLRFQSKEKIGTEFSFHIYRN
.| .  ....|... ||.|.|.. . 
HGGT--IWVESEPGGGTTFTFTLPLE
Kinase 16839.AA HATPase_c 620-736 23 4.9e-24 87.09 SMART 1-130 (130) Show / Hide 
Range on Protein: 620-736
Range on HMM: 1-130/130
Sequence Identity: 23% (35 aa)

NDGRRIKQILLNLTSNALKFTFV--------------GEIVIVIKKEILTDDLIKITVKDTGVGIPD------TLKPKLFKLYGTYDH--------NNGS
.| .|..|.|.|| .||.|.|                |.| . ..          |||.|.|.|||.       . |..|  ... |         .. .
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH---------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSR

NKHG--VGLGLVITKKLASQVGPKDSLRFQSKEKIGTEFSFHIYRNL
.  |   |||| | |... | | . ...        |.|.|.. . .
KYGGGLTGLGLSICKRIVEQHGGTIWVE--------TTFTFTLPLER
Response_reg 16839.AA Response_reg 1024-1150 27 1.3e-24 90.71 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1024-1150
Range on HMM: 1-115/115
Sequence Identity: 27% (36 aa)

VLIVDDTYFNIIALKLMLKSIKNL-TIEEAYNGQQALDILNQAKLSYQKGQRKIEDLFQIIFMDINMPIMDGIECTVNI-RKDPFYQDVKIIAVTAYSSA
||||||   .  .|. .|.    .  ..||..|..||... . .             . .|.|||||| |||.| .  | |..| . ...||..||... 
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-------------PDLIIMDINMPGMDGLELCRRIRRQHP-HPQTPIIMCTAHGDE

SESQKCFDAGMDAHICKPISRSDCFSHKN
.  .....||.. .| ||... ..  . .
DDAVEALQAGANDYITKPFDPDELHAAIR
REC 16839.AA REC 1022-1146 24 1e-20 76.03 SMART 1-150 (150) Show / Hide 
Range on Protein: 1022-1146
Range on HMM: 1-150/150
Sequence Identity: 24% (39 aa)

TRVLIVDDT----YFNIIALK------LMLKSIKNL-------TIEEAYNGQ-------QALDILNQAKLSYQKGQRKIED---LFQIIFMDINMP----
 |.|||||       .  .|.      ..|..           ...|| .|.       .||..|.. .   .|. . ..|    ...|.|||.||    
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHR---DKKEDATTDQSEPPDLIIMDIMMPGDPF

---IMDGIECTVNIRKDPFYQDVKIIAVTAYSSASESQKCFDAGMDAHICKPISRS---DCF
    ||||| .  ||        .||..||... .  .....||.|. |.||...    .  
EDGGMDGIELCRRIR--------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
YqaJ 16839.AA YqaJ 1487-1638 24 6.7e-37 118.94 Pfam 1-175 (175) Show / Hide 
Range on Protein: 1487-1638
Range on HMM: 1-175/175
Sequence Identity: 24% (44 aa)

EWHLQRKFRITASNYGQ-----IAKSAQSQ-RNKIVQDQL----------YPKFFGNEATRYGNENESAARDKYIELKKDYRYEVKE------FGLLVD-
||| .|| .||||. .      .. .  .  .. . .. .           . |..|||.. |.|.|  ||. | .  ..  |.| .      .|.... 
EWHQWRKGGITASDAAAVMNGIMGLNPYKTRPYQLWMEKTGRRPPGDPWEPCPFSQNEAMYWGHELEPIARMWYEKRTGN-LYPVCRESHINVNGFFQHL

PDYIWIAGSPDGIVFQDDKK-----IGCIEIKCPHRIKDDEKINHQKLDFLKNEE--GQIKLKDSHVYYYQCQGIMKLSKVD
|.| |.. |||||. ..| .      ||.|.|||. . ...|.|.....  ....  ..   .  . |. |||. |  .  .
PEYPWMGASPDGIIVCED-GKGEHDGGCLECKCPF-N-NSTKHNKHEWGGFNMQDVTWD---EIPDYYMCQCQHQMWVTGRE