Gene 16249 (Tetrahymena)

16249

Species: Tetrahymena
Alias: TTHERM_00842640, 307, 3741.m00046, 16249, PreTt16249, 147.m00101
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
16249.AA Protein None 1034 None Fasta, JSON
16249.kin_dom Protein Kinase Domain None 116 None Fasta, JSON
16249.NA RNA None 3105 None Fasta, JSON

Protein domain

Protein domains of 16249.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 16249.AA HisKA 233-300 37 5.9e-10 37.68 Pfam 1-69 (69) Show / Hide 
Range on Protein: 233-300
Range on HMM: 1-69/69
Sequence Identity: 37% (26 aa)

FKGKMLASLSHELRTPLNCSMQLIETLYHSGLLQDED-RDLFLAPAIQSNQLLLHIINDILDFCQINNG
 |...||..||||||||.  . ..|.|  .. | .|. |  .|  .... | ....|||.||| .| .|
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 16249.AA HisKA 233-300 26 4.9e-09 37.26 SMART 1-89 (89) Show / Hide 
Range on Protein: 233-300
Range on HMM: 1-89/89
Sequence Identity: 26% (24 aa)

FKGKMLASLSHELRTPLNCSMQLIETLYH---------SGLLQDEDR------------DLFLAPAIQSNQLLLHIINDILDFCQINNG
 |...||..||||||||.  . ..|.|           .. |..|.|              .|  .... . ....|||.||. .| .|
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 16249.AA HisK 347-502 29 5e-50 172.51 In-house 1-164 (164) Show / Hide 
Range on Protein: 347-502
Range on HMM: 1-164/164
Sequence Identity: 29% (57 aa)

SDQNRFKQVFLNILSNAVKFTEQG------KITIEVDYCQVLD--------------------LSIENSVKISIQDTGCGITPEIAKNIFNGFN-----S
||.||.||. .|..|||.|||..|      .|.|.|....  .                    |. .| ..||.||||||...|. |.||. |.     .
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

NNIYENNSLQSLFKPDLHKLSKKNFQDATFNQQNASQSQYDI-TNKVGAGLGLSISYNLAKGLG------SNRGIEFQSQPNVGSIFTFYVTDR
 ..                             .  .... ..  |. |.||||.|..|||||||       ||||..||....||.|.||. ..
-QM-----------------------------IKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 16249.AA HATPase_c 347-503 20 2.4e-20 74.84 SMART 1-130 (130) Show / Hide 
Range on Protein: 347-503
Range on HMM: 1-130/130
Sequence Identity: 20% (36 aa)

SDQNRFKQVFLNILSNAVKFTEQ--------------GKITIEVDYCQVLDLSIENSVKISIQDTGCGITP------EIAKNIFNGFNSNNIYENNSLQS
 |..|..||..|.|.||.|.|..              |.||..|.              |...|.|.||.|      |. ..||  | .    .      
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPS-----

LFKPDLHKLSKKNFQDATFNQQNASQSQYDITNKVG--AGLGLSISYNLAKGLGSNRGIEFQSQPNVGSIFTFYVTDRK
                        . .. . ..  |   ||||||. .... .|    |...      . |||..  ..
-----------------------RMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER
Kinase 16249.AA HATPase_c 347-410 32 9.7e-16 57.01 Pfam 1-64 (120) Show / Hide 
Range on Protein: 347-410
Range on HMM: 1-64/120
Sequence Identity: 32% (23 aa)

SDQNRFKQVFLNILSNAVKFTEQ-GKITIEVDYCQVLDLSIENSVKISIQDTGCGITP------EIAKNIF
 |..|..||..|...||.|.|.. |.||..|. .        . | |...|.|.||.|      |   .||
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-------DHVRITVEDNGPGIPPEMHSIAEDIPRIF
Kinase 16249.AA HATPase_c 462-502 32 7.2e-05 19.19 Pfam 80-120 (120) Show / Hide 
Range on Protein: 462-502
Range on HMM: 80-120/120
Sequence Identity: 32% (14 aa)

G--AGLGLSISYNLAKGLGSNRGIEFQSQPNVGSIFTFYVTDR
|   ||||.|.. ... .|    |...|.|. |. |||..  .
GGLTGLGLYICRRIVEQHGGT--IWVESEPGGGTTFTFTLPLE
REC 16249.AA REC 903-1028 23 3.6e-24 87.55 SMART 1-150 (150) Show / Hide 
Range on Protein: 903-1028
Range on HMM: 1-150/150
Sequence Identity: 23% (39 aa)

PSILLVDDN----DFNLYALE------IRLKPYNIY--------VDKANNGF-------LALQKVQARY------YSNQCCQNYQLIFMDIDMP------
..||.|||.      .. .|.      . |.  ..         || | .|         ||...|.         ..   ....||.||| ||      
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED

-VKNGYQAAQEINLFFKSINMKKLSPISACTAFVSEEEKRKAFESGMQYYITKPVDSQKLEDVL
   .|......|             || ..||. .|| ...|.|.|.  |||||.| . | ...
GGMDGIELCRRIR------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 16249.AA Response_reg 905-1029 28 1.1e-16 62.34 Pfam 1-115 (115) Show / Hide 
Range on Protein: 905-1029
Range on HMM: 1-115/115
Sequence Identity: 28% (36 aa)

ILLVDDNDFNLYALEIRLK-PYNI-YVDKANNGFLALQKVQARYYSNQCCQNYQLIFMDIDMPVKNGYQAAQEI-NLFFKSINMKKLSPISACTAFVSEE
.|.|||.. .. .|   |.  . .  |. | .|  ||...|..         . ||.|||.||  .|......|      . .     || .|||. .|.
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH--------PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ----TPIIMCTAHGDED

EKRKAFESGMQYYITKPVDSQKLEDVLL
 . .|.. |. .|||||.| ..| . . 
DAVEALQAGANDYITKPFDPDELHAAIR