Gene 16246 (Tetrahymena)

16246

Species: Tetrahymena
Alias: 1085, TTHERM_00842610, 3741.m00043, 147.m00098, PreTt16246, 16246
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
16246.AA Protein None 876 None Fasta, JSON
16246.kin_dom Protein Kinase Domain None 57 None Fasta, JSON
16246.NA RNA None 2631 None Fasta, JSON

Protein domain

Protein domains of 16246.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 16246.AA HisKA 446-512 21 2.6e-07 28.44 Pfam 1-69 (69) Show / Hide 
Range on Protein: 446-512
Range on HMM: 1-69/69
Sequence Identity: 21% (15 aa)

YKEKIISSFTHNLKTPLNGIFTFLQTALQ-RAEDQED-IKSMIKLSYLLGKQQMLMINDIIDYSQMIKG
 |.. ...  | |.|||..| .......   . | |. .. ...  .  ...   .|||. |.|..  |
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 16246.AA HisKA 446-512 16 4e-06 27.75 SMART 1-89 (89) Show / Hide 
Range on Protein: 446-512
Range on HMM: 1-89/89
Sequence Identity: 16% (15 aa)

YKEKIISSFTHNLKTPLNGIFTFLQTALQ----------RAEDQEDI------------KSMIKLSYLLGKQQMLMINDIIDYSQMIKG
 |.. ...  | |.|||..|  ......            . | |..            . ...  .  ...   .|||. |.|..  |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 16246.AA HisK 560-619 21 3.9e-18 62.03 In-house 1-92 (164) Show / Hide 
Range on Protein: 560-619
Range on HMM: 1-92/164
Sequence Identity: 21% (20 aa)

TDLQRLQQVIVNVLQNAIKFTFEG------EIVFKIEKSE--------------------------SNILSFQISDTGLGIENQLLTQINNM
.| .|..|...| ..||.|||..|       | .|.|...                          .|.. ....||| |.  ... .| .|
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKM
Kinase 16246.AA HATPase_c 560-616 29 6.6e-12 43.67 Pfam 1-63 (120) Show / Hide 
Range on Protein: 560-616
Range on HMM: 1-63/120
Sequence Identity: 29% (19 aa)

TDLQRLQQVIVNVLQNAIKFTFE-GEIVFKIEKSESNILSFQISDTGLGIEN------QLLTQI
.|  ||.||. |.. ||||.| | |.|  .... . . ......|.| ||        ... .|
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRI
Kinase 16246.AA HisK 630-654 35 4e-06 18.64 In-house 134-164 (164) Show / Hide 
Range on Protein: 630-654
Range on HMM: 134-164/164
Sequence Identity: 35% (11 aa)

GPE------KSFELDSIVGVGTKVKFNIYQN
|||      ..... | ||.|.. .| ||.|
GPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 16246.AA HATPase_c 560-655 15 0.000341 11.47 SMART 1-130 (130) Show / Hide 
Range on Protein: 560-655
Range on HMM: 1-130/130
Sequence Identity: 15% (23 aa)

TDLQRLQQVIVNVLQNAIKFTFE--------------GEIVFKIEKSESNILSFQISDTGLGIEN------QLLTQI--------------------NNM
.|  ||.||. |.|.||||.| |              |.|  ...       .....|.| ||        ... .|                     . 
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

QS----------LETTNYSHGPEKSFELDSIVGVGTKVKFNIYQNL
.            .  .  .|     ...      |.. | .   .
GGGLTGLGLSICKRIVEQHGGT---IWVE------TTFTFTLPLER
Response_reg 16246.AA Response_reg 739-827 30 1.3e-15 58.48 Pfam 1-84 (115) Show / Hide 
Range on Protein: 739-827
Range on HMM: 1-84/115
Sequence Identity: 30% (28 aa)

IIIVDDTPFNIKVLKCIFKDIPNL-TIQEAFNGQECIDILLKNKQMQYDLIFMDVNMPVLDGLSATQII-NDLI-SQNEILNVPVIIVTAYD
..|||| | . ..|. |...   .  . || .|.|.....   .....|||.||.||| .||| ... |   .  .|     .|.|..||..
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWW---QEHHPDLIIMDINMPGMDGLELCRRIRRQHPHPQ-----TPIIMCTAHG
REC 16246.AA REC 737-852 19 3.4e-15 57.71 SMART 1-150 (150) Show / Hide 
Range on Protein: 737-852
Range on HMM: 1-150/150
Sequence Identity: 19% (31 aa)

KNIIIVDDT----PFNIKVLK------CIFKDIPNL-------TIQEAFNGQ-------ECIDILLKNKQ----------MQYDLIFMDVNMP-------
..| ||||     | . ..|.       ....           .. || .|.       | ...| ....           ..|||.||..||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

VLDGLSATQIINDLISQNEILNVPVIIVTAYDLPIDKELQ-----VQYEIKSQFIINIPQRV
 .||. ... |            |.|..||.| . |..       . |  |   .  . .|.
GMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
PDK1_PH 16246.AA PDK1_PH 829-865 25 0.000128 13.89 In-house 60-102 (112) Show / Hide 
Range on Protein: 829-865
Range on HMM: 60-102/112
Sequence Identity: 25% (11 aa)

PID-KELQVQYE-----IKSQFIINIPQRVSNIFSLKQTEILW
|.. |.|.|.|.      ...|.|..|.|. ... .|.  . |
PWSSKDLYVEYKPDRKNNFKHFFIHTPNRTYYFEDPKGCANKW