16029

Species: Tetrahymena
Alias: 16029, PreTt16029, 736, 32.m00273, TTHERM_00323100
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
16029.AA Protein None 1820 None Fasta, JSON
16029.kin_dom Protein Kinase Domain None 118 None Fasta, JSON
16029.NA RNA None 5463 None Fasta, JSON

Protein domain

Protein domains of 16029.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 16029.AA HisKA 685-712 39 5.3e-07 27.38 Pfam 1-28 (69) Show / Hide
Range on Protein: 685-712
Range on HMM: 1-28/69
Sequence Identity: 39% (11 aa)

YKDDLLANVSHDFKTPLNGMVAQLQLIQ
 | ..|||.||...|||... . ..|.|
AKRQFLANMSHELRTPLTAIRGYAELLQ

HisKA 16029.AA HisKA 685-841 12 1.5e-05 25.68 SMART 1-89 (89) Show / Hide
Range on Protein: 685-841
Range on HMM: 1-89/89
Sequence Identity: 12% (21 aa)

YKDDLLANVSHDFKTPLNGMVAQLQLIQSLL-KNVFAQPKRQHDGLFQNNIQNSVNLEKYSKLDENNVINFKNCKSDVDATEAGGSSEQKNLGEKNVNEN
 |...|||.||...|||... . ..|.|  . |                                                                   
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYK-------------------------------------------------------------------

KLEVPKEEQIQVSDINNSTDVDDLKSQI------------FNYLYQVEQNVWMLNHLVNDIQDYSQMNNQ
              .    . |    |.              || .... .  ...|.||. |.|.. ..
--------------QRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG

HisKA 16029.AA HisKA 814-841 25 0.301081 7.34 Pfam 42-69 (69) Show / Hide
Range on Protein: 814-841
Range on HMM: 42-69/69
Sequence Identity: 25% (7 aa)

YLYQVEQNVWMLNHLVNDIQDYSQMNNQ
||  ... .  ...|.||. |.|.. ..
YLETIQREAQRMQRLINDLLDFSRIEAG

Kinase 16029.AA HisK 889-1006 37 1.4e-63 217.55 In-house 1-164 (164) Show / Hide
Range on Protein: 889-1006
Range on HMM: 1-164/164
Sequence Identity: 37% (62 aa)

SDKIRLKQILINLLSNALKFT------YEGFVKLEID-------------YIVNEETQ--------QNSLQFSVIDTGIGMPPEVQANLFKMYS------
||. |.|||||||.|||||||      ..|..|....             .|.. ...        .| .|.||.|||.|||.| | ..|||..      
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----SFDTNKI--NKHGVGLGLFISKCLVTLLGPM------NEIQVESTKGKGSTFKFQIYQN
     .|.....  |.||.|||| |.. |...|||       ..|||.|..||||||.|.||.|
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN

Kinase 16029.AA HATPase_c 889-1006 29 2e-25 90.71 Pfam 1-120 (120) Show / Hide
Range on Protein: 889-1006
Range on HMM: 1-120/120
Sequence Identity: 29% (38 aa)

SDKIRLKQILINLLSNALKFTYE-GFVKLEIDYIVNEETQQNSLQFSVIDTGIGMPP------EVQANLFKMYSSFDT--NKINKHG--VGLGLFISKCL
 | .||.|.. ||..||.|.|.| | ......         . ....|.|.|.|.||      |.....|  . ..|   .  .  |   |||| |.. .
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD------DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRI

VTLLGPMNEIQVESTKGKGSTFKFQIYQN
| ..|   .|.|||. |.|.|| | .   
VEQHG--GTIWVESEPGGGTTFTFTLPLE

Kinase 16029.AA HATPase_c 889-1007 25 6.2e-24 86.76 SMART 1-130 (130) Show / Hide
Range on Protein: 889-1007
Range on HMM: 1-130/130
Sequence Identity: 25% (38 aa)

SDKIRLKQILINLLSNALKFTYE--------------GFVKLEIDYIVNEETQQNSLQFSVIDTGIGMPP------EVQANLFKMYSSFDT---------
 | .||.|.|.|||.||.|.| |              | ......            ...|.|.|.|.||      |.. ..|  . ..|          
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH------------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDS

NKINKHG--VGLGLFISKCLVTLLGPMNEIQVESTKGKGSTFKFQIYQNL
.  .  |   |||| |.| .| ..|    |.||      .|| | .   .
RSRKYGGGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER

REC 16029.AA REC 1685-1805 22 4.3e-23 83.96 SMART 1-150 (150) Show / Hide
Range on Protein: 1685-1805
Range on HMM: 1-150/150
Sequence Identity: 22% (36 aa)

LRLLYAEDE----MFSVVMLK-----NFLKEYEKFI-------ELTVAFNGE-------LALQKIKQ---------SNHDSKPFDAVFMDSNMP------
.| | ..|.         ||.      .| | | .        . ..| .||        ||.....         .. .|.|.| ..|| .||      
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED

-VMDGPETIQEIRNLIQKSEINPLIIIT-CTSYTDKQKYIELGSDSFLSKPTNLQSILEAL
  ||| |....||         | |..|  ..  |... .|.| | ...|| ... .|...
GGMDGIELCRRIR---------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI

Response_reg 16029.AA Response_reg 1687-1806 25 1.4e-13 51.24 Pfam 1-115 (115) Show / Hide
Range on Protein: 1687-1806
Range on HMM: 1-115/115
Sequence Identity: 25% (31 aa)

LLYAEDEMFSVVMLKNFLKEYEKFIELTVAFNGELALQKIKQSNHDSKPFDAVFMDSNMPVMDGPETIQEI-RNLIQKSEINPLIIITCTSYTD---KQK
.| ..|.      |...|.. | . . ..| .|| ||.....       .| ..|| ||| ||| |....| |..  ...   . || ||.. |   ...
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-----PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ---TPIIMCTAHGDEDDAVE

YIELGSDSFLSKPTNLQSILEALI
....| . ...|| ... ...|. 
ALQAGANDYITKPFDPDELHAAIR