15795

Species: Tetrahymena
Alias: 3727.m00011, 93.m00091, TTHERM_00646890, 15795, 347, PreTt15795
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
15795.AA Protein None 1397 None Fasta, JSON
15795.kin_dom Protein Kinase Domain None 122 None Fasta, JSON
15795.NA RNA None 4194 None Fasta, JSON

Protein domain

Protein domains of 15795.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PAS 15795.AA PAS 184-252 23 0.000214 21.85 SMART 1-68 (68) Show / Hide
Range on Protein: 184-252
Range on HMM: 1-68/68
Sequence Identity: 23% (16 aa)

KFYTNILQYIPHGIAIIDEQMQVLFANSNLHSILNCSKNEDLFNALNKLNLGEVQSLNGFFQPKQQQQN
 .| .||...| || ..|........| .   ... |. | . . .  |   | . |  | .  |..|.
ERYRAILENMPDGIWVWDHDGRITYWNPAACQMFGYSPEELIGQSWWDLIHPEDRNLERFQE-HQRLQQ

HisKA 15795.AA HisKA 662-731 24 4.8e-15 57.22 SMART 1-89 (89) Show / Hide
Range on Protein: 662-731
Range on HMM: 1-89/89
Sequence Identity: 24% (22 aa)

YKMRMLASVSHELRTPLNCSISMLQIMREEL--------LRMEQKDM-----------IRDNLDPALYSSKILLNLINDILDFAQLEAG
 | ..||..||||||||.  . .........          .  ...           .|. |. .. ... ...||||.||....|||
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG

HisKA 15795.AA HisKA 662-731 34 9.1e-15 54.45 Pfam 1-69 (69) Show / Hide
Range on Protein: 662-731
Range on HMM: 1-69/69
Sequence Identity: 34% (24 aa)

YKMRMLASVSHELRTPLNCSISMLQIMREELLRMEQKDMIRDNLDPALYSSKILLNLINDILDFAQLEAG
 | ..||..||||||||.  . .......    .  ..|.|. |. .. ... ...||||.|||...|||
AKRQFLANMSHELRTPLTAIRGYAELLQD-YTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG

Kinase 15795.AA HisK 803-924 35 4.3e-60 205.97 In-house 1-164 (164) Show / Hide
Range on Protein: 803-924
Range on HMM: 1-164/164
Sequence Identity: 35% (58 aa)

SDPNRVRQIVLNLLSNALKFTNQG------QITLKAEITSQKPL------------------------AIKITCEDTGIGIPPDRYSTIFDNFNK-----
|||||..||..||.|||||||..|      .|..|.|. ....                          |.|. .|||.|.|..    ||..|..     
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----ADLQNRIKYNQCGAGLGLSISNQLAKMLCPAEL--QHQPIVVVSEVGKGSSFSFIIQDY
      . ....|.|| |.||||.|.|.|||.| | .   ....| |.|||||||.||| |.. 
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN

Kinase 15795.AA HATPase_c 803-924 31 1.6e-22 80.65 Pfam 1-120 (120) Show / Hide
Range on Protein: 803-924
Range on HMM: 1-120/120
Sequence Identity: 31% (41 aa)

SDPNRVRQIVLNLLSNALKFTNQ-GQITLKAEITSQKPLAIKITCEDTGIGIPP------DRYSTIFDNFNKAD-LQNRIKYNQCG--AGLGLSISNQLA
 ||.|..|.|.||..||.|.| . |.||.... .      . || ||.|.||||      .  ..||. | ..| .  .  ..  |   ||||.|.....
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD---DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD--SR-RKYGGGLTGLGLYICRRIV

KMLCPAELQHQPIVVVSEVGKGSSFSFIIQDY
..     .. . | | ||.|.|. |.| .   
EQ-----HGGT-IWVESEPGGGTTFTFTLPLE

Kinase 15795.AA HATPase_c 803-925 24 3.7e-20 74.21 SMART 1-130 (130) Show / Hide
Range on Protein: 803-925
Range on HMM: 1-130/130
Sequence Identity: 24% (37 aa)

SDPNRVRQIVLNLLSNALKFTNQ--------------GQITLKAEITSQKPLAIKITCEDTGIGIPP------DRYSTIFDNFNKAD------LQNRIKY
 ||.|.||...|||.||.|.| .              |.||....          || ||.|.||||      .  ..||. | ..|       ...  .
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH---------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSR

NQCG--AGLGLSISNQLAKMLCPAELQHQPIVVVSEVGKGSSFSFIIQDYL
.  |   ||||||........   ... .           . |.| .   .
KYGGGLTGLGLSICKRIVEQHG-GTIWVE-----------TTFTFTLPLER

REC 15795.AA REC 1257-1384 23 1.7e-22 81.97 SMART 1-150 (150) Show / Hide
Range on Protein: 1257-1384
Range on HMM: 1-150/150
Sequence Identity: 23% (38 aa)

AQVLVVDDN----QFNVIAIQ------QQINKLDLK--------IDMAFSGQ-------SALQKIQERIKNKFPCC----PFYLMIFMDIDMP-------
  .|.|||.    . .  ...      .   |..          .| | .|.        ||...||  ..|        . .  |.||| ||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

VMNGYETTQLITQIFKENLISSIECPIIACSAYVNPEDKQKAFESGMLDYVTKPIMLGTLDKVF
 |.|.|... |              |||...|. ..||...|.|.|. ||.|||. .  | .. 
GMDGIELCRRIR-------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI

Response_reg 15795.AA Response_reg 1259-1385 29 2.3e-22 82.65 Pfam 1-115 (115) Show / Hide
Range on Protein: 1259-1385
Range on HMM: 1-115/115
Sequence Identity: 29% (38 aa)

VLVVDDNQFNVIAIQQQIN-KLDL-KIDMAFSGQSALQKIQERIKNKFPCCPFYLMIFMDIDMPVMNGYETTQLI-TQIF-KENLISSIECPIIACSAYV
||.|||.. .  ...| .. | .. ... | .|..||...||.          . .|.|||.|| |.|.|... |  |    .       .|||.|.|. 
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH---------PDLIIMDINMPGMDGLELCRRIRRQHPHPQ-------TPIIMCTAHG

NPEDKQKAFESGMLDYVTKPIMLGTLDKVFT
...|...|.. |. ||.|||. .  | .   
DEDDAVEALQAGANDYITKPFDPDELHAAIR