Gene 15326 (Tetrahymena)

15326

Species: Tetrahymena
Alias: 15326, 215.m00069, PreTt15326, 3809.m00237, TTHERM_01055720, 968
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
15326.AA Protein None 1082 None Fasta, JSON
15326.kin_dom Protein Kinase Domain None 126 None Fasta, JSON
15326.NA RNA None 3249 None Fasta, JSON

Protein domain

Protein domains of 15326.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 15326.AA HisKA 399-464 24 1.1e-11 43.75 Pfam 1-69 (69) Show / Hide 
Range on Protein: 399-464
Range on HMM: 1-69/69
Sequence Identity: 24% (17 aa)

YKDQLLFTISHDLKTPLNGMQSILQAALL--KDNVEQ-IKKMIQLVQVNGDLLNYLIKDILDYAQVIHK
 | |.| ..||.|.|||....  .....   . . || ...... .|  .. .. || |.||...  . 
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 15326.AA HisKA 399-464 20 1.7e-11 45.45 SMART 1-89 (89) Show / Hide 
Range on Protein: 399-464
Range on HMM: 1-89/89
Sequence Identity: 20% (18 aa)

YKDQLLFTISHDLKTPLNGMQSILQAALL-----------KDNVEQI------------KKMIQLVQVNGDLLNYLIKDILDYAQVIHK
 |.|.| ..||.|.|||....  .....            . . ||.            ..... .|  .| .. || |.||...  . 
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 15326.AA HisK 792-886 34 2.7e-35 123.59 In-house 36-164 (164) Show / Hide 
Range on Protein: 792-886
Range on HMM: 36-164/164
Sequence Identity: 34% (44 aa)

IKTMNNYNI-------QQQDQEN---------EIIQITVTDTGLGMDKDLQKQLFSMFG-----------TFEQKGV--NKEGVGLGLIITQSLSQLLGP
.. .|..|.       .|..|||         ..|||.| ||| ||....||..| |||           ||...    |..|.||||.| ..| ..|||
VEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQHQMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGP

KK-----DNIKVKSIKDQGSSFSFKIYRR
..     ..|.|.| ...||.|||.|| .
EHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 15326.AA HisK 510-594 27 5.1e-14 47.21 In-house 1-70 (164) Show / Hide 
Range on Protein: 510-594
Range on HMM: 1-70/164
Sequence Identity: 27% (27 aa)

TDEIRLKQIIFNFVSNALKFTFQG------SITIKVEEVNDCGEIEDELNNDPDFTQSLNIQINNNQAFYNVNN---INNLSSN---KLNIQQLNYY
.|. |.|||..|..|||||||..|      .|.||||. |.. .|                         .  |   |... .|   . ..|| |..
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNI-------------------------KY-NSIFIQKIQENMVQE-QLQQKNLI
Kinase 15326.AA HATPase_c 804-886 22 2.2e-11 41.84 Pfam 32-120 (120) Show / Hide 
Range on Protein: 804-886
Range on HMM: 32-120/120
Sequence Identity: 22% (21 aa)

DQENEIIQITVTDTGLGMDK------DLQKQLFSMFGTFEQ--KGVNKEG--VGLGLIITQSLSQLLGPKKDNIKVKSIKDQGSSFSFKIYRR
..... ..|||.|.| |...      ... ..|  |.....     . .|   |||| | . .....| .   | | |  ..|. |.|.. ..
HRDDDHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQHGGT---IWVESEPGGGTTFTFTLPLE
Kinase 15326.AA HATPase_c 510-887 7 2.3e-10 41.66 SMART 1-130 (130) Show / Hide 
Range on Protein: 510-887
Range on HMM: 1-130/130
Sequence Identity: 7% (32 aa)

TDEIRLKQIIFNFVSNALKFTFQ--------------GSITIKVEEVNDCGEIEDELNNDPDFTQSLNIQINNNQAFYNVNNINNLSSNKLNIQQLNYYN
.|..||.|.. | ..||.|.| .              | ||..|.                                                       
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------------------------------------------------------

DFDSIVEKQTGFDEELLNQQNIQNLYSPNFPSNSNFLTNQKDSKLFQTPQLISNPIQARINSTPISQREFNKKHNVNLTKYCFTNNIEQFKKQINNEQLQ
                                                                                                    
----------------------------------------------------------------------------------------------------

NNQIANENQNAVIDIPNKKQNYHAIFDQSSIAQQHQSQLRKSTRLQKQITNQVTHSLRNSKNTQLSPSNTPDQPEKLLQQQNLQIEIDNESHKSLAIKTM
                                                                                                    
----------------------------------------------------------------------------------------------------

NNYNIQQQDQENEIIQITVTDTGLGMDK------DLQKQLFSMFGTFEQ---------KGVNKEG--VGLGLIITQSLSQLLGPKKDNIKVKSIKDQGSS
               .|||.|.| |...      ......|  |.....         .  . .|   |||| | .......| .   |.|       . 
---------------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGT---IWVE------TT

FSFKIYRRL
|.|.. ...
FTFTLPLER
Kinase 15326.AA HATPase_c 510-549 39 7e-10 36.63 Pfam 1-41 (120) Show / Hide 
Range on Protein: 510-549
Range on HMM: 1-41/120
Sequence Identity: 39% (16 aa)

TDEIRLKQIIFNFVSNALKFTFQ-GSITIKVEEVNDCGEIE
.|..||.|.. |.|.||.|.| . | ||..|.. .|  .|.
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDDDHVRIT
REC 15326.AA REC 959-1076 20 6.6e-24 86.67 SMART 1-150 (150) Show / Hide 
Range on Protein: 959-1076
Range on HMM: 1-150/150
Sequence Identity: 20% (34 aa)

YKMLIVDDV----QFNISVFK------CMLHQLQNV-------TFDHAYNGQ-------QAIDKLKKN-------------NYDIVFMDINMP-------
.. |||||     . .  . .       .| ..          . | | .|.       .|...|...             ..|...|||.||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

VMDGIQATKQIRILIQQKLVQPTIIIALTGDDIDSDSNKFSSKGFNAALSKPIKLEDLYFVL
 ||||.....||            ||.||. | ..|  .    | .. ..||...|.|  ..
GMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 15326.AA Response_reg 961-1077 27 1.4e-19 72.74 Pfam 1-115 (115) Show / Hide 
Range on Protein: 961-1077
Range on HMM: 1-115/115
Sequence Identity: 27% (33 aa)

MLIVDDVQFNISVFKCMLH-QLQN-VTFDHAYNGQQAIDKLKKNNYDIVFMDINMPVMDGIQATKQI-RILI-QQKLVQPTIIIALTGDDIDSDSNKFSS
 ||||| . . .... .|  . .  |.   |..|..|....... .|...|||||| |||......| | .   |     | ||..|. . ..|  .   
VLIVDDHPLMREGLRQILEQKEGYEVVA-EADDGEEALEWWQEHHPDLIIMDINMPGMDGLELCRRIRRQHPHPQ-----TPIIMCTAHGDEDDAVEALQ

KGFNAALSKPIKLEDLYFVLK
 | |  ..||.....|.  ..
AGANDYITKPFDPDELHAAIR