Gene 14574 (Tetrahymena)

14574

Species: Tetrahymena
Alias: PreTt14574, 2.m02258, 158, 14574, TTHERM_00040380, 3825.m02939
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
14574.AA Protein None 1235 None Fasta, JSON
14574.NA RNA None 3708 None Fasta, JSON
14574.kin_dom Protein Kinase Domain None 114 None Fasta, JSON

Protein domain

Protein domains of 14574.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 14574.AA HisKA 567-638 23 1.8e-11 45.32 SMART 1-89 (89) Show / Hide 
Range on Protein: 567-638
Range on HMM: 1-89/89
Sequence Identity: 23% (21 aa)

YKNRMLASISHELRTPLNCSIQMLNLLIKNF------EEEKFDTQEI-----------IEMLIKPALNSNYILLNIINDILDYAQINTG
 |...||..||||||||.  . .. || ...      .. . | ...           .. ... ....   ....|||.||...| .|
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA 14574.AA HisKA 567-638 29 1.8e-11 42.96 Pfam 1-69 (69) Show / Hide 
Range on Protein: 567-638
Range on HMM: 1-69/69
Sequence Identity: 29% (21 aa)

YKNRMLASISHELRTPLNCSIQMLNLLIKNFEEEKFDTQEIIEMLIKPALNSNYILLNIINDILDYAQINTG
 |...||..||||||||.  . .. || .   ... | ..... ... ....   ....|||.||...| .|
AKRQFLANMSHELRTPLTAIRGYAELLQD---YTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
Kinase 14574.AA HisK 685-798 36 4.6e-59 202.55 In-house 1-164 (164) Show / Hide 
Range on Protein: 685-798
Range on HMM: 1-164/164
Sequence Identity: 36% (60 aa)

SDYNRIRQVILNLLCNSLKFTQKG------FIRIFFT--------------------------LESPKLIRVDVSDTGCGIPEANIKEIFEAFG------
||.|||.|...||..|.|||||||      .|.| ..                          |....||...|.|||||.|| ..|.||..||      
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----NKLNSKY-LNTKGAGFGLSITNNLAMGLG------GNRKMIVKSKINEGSTFSFYIIDR
     .. ...  .|..|.|.||.| ||||.|||      |||.  |.|. ..|||||||| ..
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 14574.AA HATPase_c 685-798 29 2.2e-21 76.69 Pfam 1-120 (120) Show / Hide 
Range on Protein: 685-798
Range on HMM: 1-120/120
Sequence Identity: 29% (37 aa)

SDYNRIRQVILNLLCNSLKFTQK-GFIRIFFTLESPKLIRVDVSDTGCGIPE------ANIKEIFEAFGNKLN-SKYLNTKG--AGFGLSITNNLAMGLG
 | .|..||..||. |..|.|.. | |..  . .    .|. |.|.|.|||.       .|  |||.|.   . |   ...|   |.||.| . ..  .|
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQHG

GNRKMIVKSKINEGSTFSFYIIDR
|   . | |....|.||.|..  .
GT--IWVESEPGGGTTFTFTLPLE
Kinase 14574.AA HATPase_c 685-799 27 9.7e-21 76.14 SMART 1-130 (130) Show / Hide 
Range on Protein: 685-799
Range on HMM: 1-130/130
Sequence Identity: 27% (39 aa)

SDYNRIRQVILNLLCNSLKFTQKGF------------IRIFFTLESPKLIRVDVSDTGCGIPE------ANIKEIFEAFGNKLN--------SKYLNTKG
 | .|.|||..||| |..|.|..|.             ||  ...     |. |.|.|.|||.        |. |||.|.   .        |.  ...|
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-----RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKYGG

--AGFGLSITNNLAMGLGGNRKMIVKSKINEGSTFSFYIIDRD
   | |||| ....  .||   . |       .||.|..  . 
GLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER
REC 14574.AA REC 1098-1223 20 1.3e-21 79.0 SMART 1-150 (150) Show / Hide 
Range on Protein: 1098-1223
Range on HMM: 1-150/150
Sequence Identity: 20% (33 aa)

NQILIVDDN----DFNLYSLQ------LILKTYGFV--------VDKSNSGM-------DAISKVKLKYSNQSCCQ-----YYKVIFMDIDMP-------
  ||||||.      ..  |.      ..|.  |.         ||   .|        .|. ... . ....         . .|.||| ||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

IMDGHQTTTEIIKFYLDQKSSFKPVISACSAYVQDSEKQKAFQKGMKYYITKPINIKQLEQIL
 ||| ... .|              | ...|. ... ...|.. |.  |||||.....| . .
GMDGIELCRRIR------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 14574.AA Response_reg 1100-1224 27 2.8e-20 75.21 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1100-1224
Range on HMM: 1-115/115
Sequence Identity: 27% (35 aa)

ILIVDDNDFNLYSLQLILK-TYGF-VVDKSNSGMDAISKVKLKYSNQSCCQYYKVIFMDIDMPIMDGHQTTTEI-IKFY-LDQKSSFKPVISACSAYVQD
.|||||.. ..  |. ||.  .|. ||.   .| .|. ... .         . .|.|||.|| ||| .....|  . .  .      . | .|.|. ..
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH--------PDLIIMDINMPGMDGLELCRRIRRQHPHPQ------TPIIMCTAHGDE

SEKQKAFQKGMKYYITKPINIKQLEQILA
. ...|.| |. .|||||... .| ....
DDAVEALQAGANDYITKPFDPDELHAAIR