Gene 14296 (Tetrahymena)

14296

Species: Tetrahymena
Alias: TTHERM_00031640, 168, 14296, 3825.m02680, PreTt14296, 2.m02418
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
14296.AA Protein None 1668 None Fasta, JSON
14296.kin_dom Protein Kinase Domain None 119 None Fasta, JSON
14296.NA RNA None 5007 None Fasta, JSON

Protein domain

Protein domains of 14296.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 14296.AA HisKA 972-1037 28 1.5e-14 53.65 Pfam 1-69 (69) Show / Hide 
Range on Protein: 972-1037
Range on HMM: 1-69/69
Sequence Identity: 28% (20 aa)

NRSKMLNYVVHEIRSPLSSIMNYLHSSIE--SLTKEL-YDQFIDPALSSAQMLNVLIQDLLDMAQMKAG
 ....| .. ||.| ||..|. |..   .   |. |  . .... ....|| .. ||.||||.... ||
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 14296.AA HisKA 972-1037 22 4.8e-14 53.91 SMART 1-89 (89) Show / Hide 
Range on Protein: 972-1037
Range on HMM: 1-89/89
Sequence Identity: 22% (20 aa)

NRSKMLNYVVHEIRSPLSSIMNYLHSSIE-----------SLTKEL------------YDQFIDPALSSAQMLNVLIQDLLDMAQMKAG
 ....| .. ||.| ||..|. |..   .            |. |             | .... ....|. .. ||.||||.... ||
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 14296.AA HisK 1086-1204 35 5.5e-53 182.34 In-house 1-164 (164) Show / Hide 
Range on Protein: 1086-1204
Range on HMM: 1-164/164
Sequence Identity: 35% (58 aa)

SDQLRIKQILINLISNAVKFTDEG------SIRIEVNMIE--------------------------NKIYRFSVRDTGIGITDDQKKKLFSEFSKIET--
||. |||||||||||||.|||..|      .|.|.|. |.                          ......|| |||.|....|.||.|  |..| .  
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

--------TQTDILNPKGVGLGLVISNILAKSLAPKH---MPAGLEIISGKSKGSEFFFHILDF
        .|   .|..|.||||.|.|.||| | |.|   .  |....| . |||.| |.|...
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 14296.AA HATPase_c 1086-1205 20 7.9e-20 73.11 SMART 1-130 (130) Show / Hide 
Range on Protein: 1086-1205
Range on HMM: 1-130/130
Sequence Identity: 20% (30 aa)

SDQLRIKQILINLISNAVKFTDE--------------GSIRIEVNMIENKIYRFSVRDTGIGITD------DQKKKLFSEFSKIETTQ------TDILNP
 |. |..|.|.||..||.|.|.|              | |...|.       |..|.|.|.||..      .. ...|  | . .  .       .  . 
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

KG--VGLGLVISNILAKSLAPKHMPAGLEIISGKSKGSEFFFHILDFS
.|   |||| |.. ... .  .     ...       ..| |..    
GGGLTGLGLSICKRIVEQHGGT-----IWVE------TTFTFTLPLER
Kinase 14296.AA HATPase_c 1086-1204 24 2e-19 69.84 Pfam 1-120 (120) Show / Hide 
Range on Protein: 1086-1204
Range on HMM: 1-120/120
Sequence Identity: 24% (31 aa)

SDQLRIKQILINLISNAVKFTDE-GSIRIEVNMIENKIYRFSVRDTGIGITD------DQKKKLFSEFSKIETTQTDILNPKG--VGLGLVISNILAKSL
 |..|..|.. ||..||.|.| | | |...|   .    |..|.|.|.||..      ..  ..|  | . .    .  . .|   |||| |.. ...  
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD-SR-RKYGGGLTGLGLYICRRIVEQ-

APKHMPAGLEIISGKSKGSEFFFHILDF
    .   ... |   .|..| |..   
----HGGTIWVESEPGGGTTFTFTLPLE
Response_reg 14296.AA Response_reg 1508-1633 25 1.5e-15 58.3 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1508-1633
Range on HMM: 1-115/115
Sequence Identity: 25% (32 aa)

ILIVDDETFQCNSLSQLIHSITKQ-QCDKATSCDSCLKHIVQKHQQNQCCPSYQLILLDLNMFPSKDGFETLIEI-QKYHTQVRLQMPKVVACTGEADEE
.|||||.  ..  | |..        .. |..  ..|. . |.|.       . ||..|.|| |  ||.|.. .| .. . .     .....||. .||.
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWW-QEHH-------PDLIIMDINM-PGMDGLELCRRIRRQHP-HPQ---TPIIMCTAHGDED

KKQQCIIAGFIDILEKPIQVDQLKSILT
 ..... ||  |.. ||.  |.|. .. 
DAVEALQAGANDYITKPFDPDELHAAIR
REC 14296.AA REC 1506-1632 17 1.6e-15 58.8 SMART 1-150 (150) Show / Hide 
Range on Protein: 1506-1632
Range on HMM: 1-150/150
Sequence Identity: 17% (29 aa)

SNILIVDDE----TFQCNSLS------QLIHSITKQ-------QCDKATSCD-------SCLKHIVQKHQQNQCCP-----SYQLILLDLNMFP------
 .||||||.      ..  |.      .|  .   .       ..| | . .         |. . ......   .      ..||..|..|        
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

SKDGFETLIEIQKYHTQVRLQMPKVVACTGEADEEKKQQCIIAGFIDILEKPIQVDQLKSIL
  ||.|.. .|.           .....|. .||| ..... ||  | . ||.. ..|   .
GMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI