Gene 13539 (Tetrahymena)

13539

Species: Tetrahymena
Alias: TTHERM_00415680, PreTt13539, 102, 13539, 3833.m00738, 45.m00184
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
13539.AA Protein None 2111 None Fasta, JSON
13539.kin_dom Protein Kinase Domain None 140 None Fasta, JSON
13539.NA RNA None 6336 None Fasta, JSON

Protein domain

Protein domains of 13539.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PAS 13539.AA PAS 739-805 13 0.000378 21.03 SMART 1-68 (68) Show / Hide 
Range on Protein: 739-805
Range on HMM: 1-68/68
Sequence Identity: 13% (9 aa)

KMYQDILNLIPEGVALINSSNQLVYANKTLSKILQCSKNQIVNILLNLATKSKDS--DATSQKIAMNTN
 .|. ||. .|.|. ...   . .|.| .  ...  |. ...   .       |   ..  . .    .
ERYRAILENMPDGIWVWDHDGRITYWNPAACQMFGYSPEELIGQSWWDLIHPEDRNLERFQE-HQRLQQ
HisKA 13539.AA HisKA 1220-1342 14 1.5e-05 25.65 SMART 1-89 (89) Show / Hide 
Range on Protein: 1220-1342
Range on HMM: 1-89/89
Sequence Identity: 14% (20 aa)

YRMKMFASLSHELRTPLNCSISMLQQVKNIM-KEDMQADQKQPENILSIKDKIRNKLQAQNKSQSQSNQLVSQNQKAEEGQVSLKLLEKMSDYI------
 . ...|..||||||||.  . ...  .. . |                                               |. ..  .  .. .      
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYK-----------------------------------------------QRYHHWTDLDPEQRLPMLRR

------QTYIDPALNSNKLLLNLINDILDFVQIDSG
      . |.. .... . ...||||.||. .|..|
EFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA 13539.AA HisKA 1313-1342 33 0.000151 18.84 Pfam 40-69 (69) Show / Hide 
Range on Protein: 1313-1342
Range on HMM: 40-69/69
Sequence Identity: 33% (10 aa)

QTYIDPALNSNKLLLNLINDILDFVQIDSG
. |.. .... . ...||||.||| .|..|
REYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 13539.AA HisKA 1220-1237 50 0.0002 18.41 Pfam 1-18 (69) Show / Hide 
Range on Protein: 1220-1237
Range on HMM: 1-18/69
Sequence Identity: 50% (9 aa)

YRMKMFASLSHELRTPLN
 . ...|..||||||||.
AKRQFLANMSHELRTPLT
Kinase 13539.AA HisK 1391-1530 34 8e-50 171.85 In-house 1-164 (164) Show / Hide 
Range on Protein: 1391-1530
Range on HMM: 1-164/164
Sequence Identity: 34% (60 aa)

SDPNRIRQVVLNFLSNAMKFT------SQGQIIVSATLINYKDS-------TNQISSQ-SQSDFLAEEDLKNNQNNIVEISVEDQGIGISPEDIQKIFTI
||||||.|...|..||| |||      .||.| .....||....        ..| .. .|      |  ...|.|...|||.| |.|...|...||| .
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQ------E--QLQQKNLIQISVQDTGCGMPEEQQKKIFKM

FNKID----------LGENQSLNSQGCGLGLTISNSLG------PI--NKGGIRVQSEIGHGSVFSILVEDR
|..||            .|...|..||||||||.|.|       ..  ...|| |||| |.|| ||......
FGNIDDQHQMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 13539.AA HATPase_c 1391-1530 29 3.4e-23 82.98 Pfam 1-120 (120) Show / Hide 
Range on Protein: 1391-1530
Range on HMM: 1-120/120
Sequence Identity: 29% (44 aa)

SDPNRIRQVVLNFLSNAMKFTSQ-GQIIVSATLINYKDSTNQISSQSQSDFLAEEDLKNNQNNIVEISVEDQGIGISP------EDIQKIFTIFNKID-L
 ||.|..|||.|...||.|.| . |.| |...  .                           . |.|.||| |.||.|      |||..||  | . | .
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD---------------------------DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD

GENQSLNSQG--CGLGLTISNSLGPINKGGIRVQSEIGHGSVFSILVEDR
      ...|   ||||.|.. .     | |.|.||.|.|..|.. .  .
--SR-RKYGGGLTGLGLYICRRIVEQHGGTIWVESEPGGGTTFTFTLPLE
Kinase 13539.AA HATPase_c 1391-1531 24 3.8e-22 80.83 SMART 1-130 (130) Show / Hide 
Range on Protein: 1391-1531
Range on HMM: 1-130/130
Sequence Identity: 24% (41 aa)

SDPNRIRQVVLNFLSNAMKFTSQ--------------GQIIVSATLINYKDSTNQISSQSQSDFLAEEDLKNNQNNIVEISVEDQGIGISP------EDI
 ||.|.|||..| |.|| |.| .              |.| |..                                  .|.||| |.||.|      |||
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH---------------------------------RITVEDNGPGIPPEMHKSIEDI

QKIFTIFNKID------LGENQSLNSQG--CGLGLTISNSLGPINKGGIRVQSEIGHGSVFSILVEDRE
..||  | . |         ..| ...|   ||||.|....     | |.|.      ..|.. .  ..
PRIFEPFYRTDDSPSRMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGTIWVE------TTFTFTLPLER
REC 13539.AA REC 1942-2068 23 2.4e-28 101.41 SMART 1-150 (150) Show / Hide 
Range on Protein: 1942-2068
Range on HMM: 1-150/150
Sequence Identity: 23% (38 aa)

AQLLVVDDN----LFNMHAIT------MQLKTYGFK--------IDQAQNGQ-------KAVELVEKRY------YENTCCKSYKLIFMDIEMP------
   |.|||.      ......      . |.  |.         .|.| .|.        |.||...         ..   . . ||.|||.||      
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED

-IKNGYEATQDIRNFFNGNSYISKQPIIVACTAYVSDEDKSKALANGMDDFIKKPVFQEALDLLL
   .|.|... ||              |...||. ..||. .||. |.||.| ||. .| |   .
GGMDGIELCRRIR-------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 13539.AA Response_reg 1944-2069 26 4.6e-19 70.85 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1944-2069
Range on HMM: 1-115/115
Sequence Identity: 26% (34 aa)

LLVVDDNLFNMHAITMQLK-TYGF-KIDQAQNGQKAVELVEKRYYENTCCKSYKLIFMDIEMPIKNGYEATQDI-RNFF-NGNSYISKQPIIVACTAYVS
.|.|||.  .. ...  |.  .|. ... |..|. |.|.....         . ||.|||.||  .|.|... | |.    .       . |..|||. .
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH--------PDLIIMDINMPGMDGLELCRRIRRQHPHPQ-------TPIIMCTAHGD

DEDKSKALANGMDDFIKKPVFQEALDLLLN
..|. .||  |..|.| ||. ...|   ..
EDDAVEALQAGANDYITKPFDPDELHAAIR