Gene 13303 (Tetrahymena)

13303

Species: Tetrahymena
Alias: 3707.m00337, 1131, 13303, 4.m00702, PreTt13303, TTHERM_00071130
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
13303.AA Protein None 1712 None Fasta, JSON
13303.kin_dom Protein Kinase Domain None 120 None Fasta, JSON
13303.NA RNA None 5139 None Fasta, JSON

Protein domain

Protein domains of 13303.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 13303.AA HisKA 446-519 19 0.000146 17.34 SMART 1-89 (89) Show / Hide 
Range on Protein: 446-519
Range on HMM: 1-89/89
Sequence Identity: 19% (17 aa)

FKSQLLNYIQHIAKTPLNSIIQLSETMEQWF-------PLSPNNKQICNDI--------KDNLEIIKKNGLILHHQVQSIIDLQQINCN
 |.|.| .. |  .|||..|. ..|... |.           . .|. . .        .. ||.|.. .  . .... . || .|  .
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 13303.AA HisK 566-685 26 7.3e-42 145.39 In-house 1-164 (164) Show / Hide 
Range on Protein: 566-685
Range on HMM: 1-164/164
Sequence Identity: 26% (43 aa)

TDENRLTQILIEMIGNSVKFTKEN-----DSIKIQASIQKTYTV-----------------------SLICITIIDTGSGMSPEQVAIINSSASLEN---
.|.||. |||| .|.|..|||...      .|||..... |...                        ||.|...||| ||..||.  |    .  .   
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-------IPVPNSHFRQGPGIGLEVSRKLIGLLGPF------SKFNLKSAVGEGCQFKFWLYMN
       .    .. ..| |.|| ....|...|||.       .. ..| ||.|. |.|..| |
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 13303.AA HATPase_c 566-685 21 1.7e-14 52.67 Pfam 1-120 (120) Show / Hide 
Range on Protein: 566-685
Range on HMM: 1-120/120
Sequence Identity: 21% (29 aa)

TDENRLTQILIEMIGNSVKFTKENDSIKIQASIQKTYTVSLICITIIDTGSGMSPEQVAIINSSASLENIPVPNSHFR----------------QG--PG
.|..|| |.. . ..|..|.|.|.. |.. .. ..      ..||..|.| |..|| .            . .    |                .|   |
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD----DHVRITVEDNGPGIPPEMH------------SIAEDIPRIFEPFYRTDPDSRRKYGGGLTG

IGLEVSRKLIGLLGPFSKFNLKSAVGEGCQFKFWLYMN
.|| ..|... ..|   .  . | .|.|. | |.| . 
LGLYICRRIVEQHG--GTIWVESEPGGGTTFTFTLPLE
Kinase 13303.AA HATPase_c 566-686 18 8.8e-12 46.38 SMART 1-130 (130) Show / Hide 
Range on Protein: 566-686
Range on HMM: 1-130/130
Sequence Identity: 18% (28 aa)

TDENRLTQILIEMIGNSVKFTKE-------------NDSIKIQASIQKTYTVSLICITIIDTGSGMSPEQVAIINSSASLENIPVP--------------
.|..|| |.|.. ..|..|.|.|             .. |.. ..          .||..|.| |..|| .        ...|  |              
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH----------RITVEDNGPGIPPEMH-K-SI-EDIPRIFEPFYRTDDSPSRMCPD

-NSHFRQG--PGIGLEVSRKLIGLLGPFSKFNLKSAVGEGCQFKFWLYMNL
 .|. ..|   |.|| ...... ..|   ...        . | |.| . .
SRSRKYGGGLTGLGLSICKRIVEQHGGTIWVE--------TTFTFTLPLER
REC 13303.AA REC 1577-1698 21 1.9e-28 101.78 SMART 1-150 (150) Show / Hide 
Range on Protein: 1577-1698
Range on HMM: 1-150/150
Sequence Identity: 21% (35 aa)

TLILIVDDT----TFNRIVLK------QMFKSSQNI-------VIQEAINGQ-------DAIDKIKTLK--------ETQNRTFNLIFMDLNMP------
  ||||||       .| .|.      .....           |. || .|.       .|........          |   . ||.||..||      
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED

-IMDGFEALKQIQNLIHQKYISWVPVVAVTAYDT--EVENCRNKGFDGFISKPVRIKEMVRSL
  |||.|....|.           |....||.|.   .. ..  | |..|.||....|..  .
GGMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 13303.AA Response_reg 1579-1699 26 4.9e-26 95.82 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1579-1699
Range on HMM: 1-115/115
Sequence Identity: 26% (34 aa)

ILIVDDTTFNRIVLKQMFKSSQNI-VIQEAINGQDAIDKIKTLKETQNRTFNLIFMDLNMPIMDGFEALKQI-QNLI-HQKYISWVPVVAVTAYDT--EV
.|||||   .| .|.|... .  . |. || .|..|........      . ||.||.||| |||.|....| ...  .|     .|....||...   .
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH------PDLIIMDINMPGMDGLELCRRIRRQHPHPQ-----TPIIMCTAHGDEDDA

ENCRNKGFDGFISKPVRIKEMVRSLI
. .   | ...|.||. . |..  . 
VEALQAGANDYITKPFDPDELHAAIR