Gene 12733 (Tetrahymena)
12733
Sequence
Protein domains of 12733.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 12733.AA | HisK | 960-1071 | 33 | 2.2e-52 | 180.34 | In-house | 1-164 (164) | Show / Hide |
Range on Protein: 960-1071
Range on HMM: 1-164/164
Sequence Identity: 33% (55 aa)
NDQKRIKQVLINMICNSLKYTPKG------YCKVV----------------IQKSEVN--------QDVLVVSVKDSGEGMDENTKHKLFQLYE------
.|. ||||.|||.|.|.||.| || | |. |||.. | .... .||.|.| ||.|....|.|....
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH
---------NTDSD-IHGVGLGLVICRNIIGFLGPS------ENIEVESQLGKGSTFSFQIYIK
. .. ||.||||.||.|....|||. .|.|.|. ||||||||.|| .
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
|
|||||||||
| Kinase | 12733.AA | HATPase_c | 960-1071 | 30 | 2.9e-21 | 76.26 | Pfam | 1-120 (120) | Show / Hide |
Range on Protein: 960-1071 Range on HMM: 1-120/120 Sequence Identity: 30% (38 aa) NDQKRIKQVLINMICNSLKYTPK-GYCKVVIQKSEVNQDVLVVSVKDSGEGMDE------NTKHKLFQLYENTDS----DIHG--VGLGLVICRNIIGFL .|. |..||. | . |..|.||. | .| . . . | ....|.|.| |... ..|. . ||. .. | |||| ||| |. . GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD---DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSRRKYGGGLTGLGLYICRRIVEQH GPSENIEVESQLGKGSTFSFQIYIK | . |.|||. |.|.||.| . . GGT--IWVESEPGGGTTFTFTLPLE |
|||||||||
| Kinase | 12733.AA | HATPase_c | 960-1072 | 22 | 1.7e-18 | 68.73 | SMART | 1-130 (130) | Show / Hide |
Range on Protein: 960-1072 Range on HMM: 1-130/130 Sequence Identity: 22% (33 aa) NDQKRIKQVLINMICNSLKYTPKGY-----------CKVVIQKSEVNQDVLVVSVKDSGEGMDE------NTKHKLFQLYENTD------------SDIH .|..|..|||.| . |..|.||.|. . . . . ...|.|.| |... ..|. . || ... GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKYG G--VGLGLVICRNIIGFLGPSENIEVESQLGKGSTFSFQIYIKN | |||| ||..|. .| . |.|| .||.| . .. GGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER |
|||||||||
| Response_reg | 12733.AA | Response_reg | 1448-1539 | 34 | 1.7e-16 | 61.67 | Pfam | 1-84 (115) | Show / Hide |
Range on Protein: 1448-1539 Range on HMM: 1-84/115 Sequence Identity: 34% (32 aa) ILIVDDNFFNQCVLESLLKNVHGIELIDKAENGQIAIQKIQDLHLQYGFTYDLILMDWQMPVLDGLQATVMI-RQLEFLQEHPPYIIFVTASS .|||||. .. .| .|.. .|.| .. |..|. |....| .| .|||.||..|| .|||... .| ||... | . ||..|| . VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH------PDLIIMDINMPGMDGLELCRRIRRQHPHPQ---TPIIMCTAHG |
|||||||||
| REC | 12733.AA | REC | 1446-1560 | 20 | 1.7e-10 | 42.14 | SMART | 1-150 (150) | Show / Hide |
Range on Protein: 1446-1560 Range on HMM: 1-150/150 Sequence Identity: 20% (33 aa) KRILIVDDN----FFNQCVLE-----SLLKNVHGIE-------LIDKAENGQ-------IAIQKIQDLHLQYG-------FTYDLILMDWQMP------- .|||||||. .. .|. ..| .|.| .| | .|. |....| .. ... .|||.||..|| MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG VLDGLQATVMIRQLEFLQEHPPYIIFVTASSA-QEKNKI--------IIADFEYNNMINSS .||.... .|| ||..|| . . . . | .|. . .. GMDGIELCRRIR----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI |
|||||||||