Gene 11754 (Tetrahymena)

11754

Species: Tetrahymena
Alias: TTHERM_00011480, 11754, 1.m00802, PreTt11754, 936
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
11754.AA Protein None 1646 None Fasta, JSON
11754.kin_dom Protein Kinase Domain None 88 None Fasta, JSON
11754.NA RNA None 4941 None Fasta, JSON

Protein domain

Protein domains of 11754.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 11754.AA HisKA 875-951 24 1.8e-09 35.95 Pfam 1-69 (69) Show / Hide 
Range on Protein: 875-951
Range on HMM: 1-69/69
Sequence Identity: 24% (19 aa)

QKQQIVSYLSHELRNPLNCIINILDTIDY-DIQALKKVQQKQVDIVEIQNNIATALQNSKYILNLSNDYLDMARIKAD
.|.| ....|||||.||. |.  ....   . .  ..          ..  . |... ......| || ||..|| | 
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQM---------RREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 11754.AA HisKA 875-951 24 1.1e-08 36.07 SMART 1-89 (89) Show / Hide 
Range on Protein: 875-951
Range on HMM: 1-89/89
Sequence Identity: 24% (22 aa)

QKQQIVSYLSHELRNPLNCIINILDTIDY--------------DIQALKKVQQKQVDIVEIQNNIATALQNSKYILNLSNDYLDMARIKAD
.|.| ....|||||.||. |.  ....                . |.|.   .      |..  . |... ......| || ||..|| | 
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRR-E-FNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 11754.AA HisK 1009-1160 30 6.4e-45 155.56 In-house 1-164 (164) Show / Hide 
Range on Protein: 1009-1160
Range on HMM: 1-164/164
Sequence Identity: 30% (59 aa)

SDQERIKQVIINLISNALKFTHNG------RIFIQSEYNS--------------------------LNSIQVSIKDTGIGIEKSKLKQLFKAFGKIDD--
||. ||||..||||||||||| .|       | |. |. .                           | ||.|..|||.|. ....|..||.||.|||  
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

--------EETQNYNQQGVGLGLLISNMLSIQLAKPPTNENMSSQINQNINSNSIMNINQSNQSIQQNNKQDKGLKVESEKGIGSTFTLTITDH
        .. ...||.|.|||| |.|.|  .| . . .                             | . .|..|.||.|.||||.  | ..
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQ-----------------------------N-GNRGIQVQSEVGKGSTFSFYIYNN
Kinase 11754.AA HATPase_c 1009-1096 25 6.6e-21 74.99 Pfam 1-94 (120) Show / Hide 
Range on Protein: 1009-1096
Range on HMM: 1-94/120
Sequence Identity: 25% (25 aa)

SDQERIKQVIINLISNALKFTHN-GRIFIQSEYNSLNSIQVSIKDTGIGIEK------SKLKQLFKAFGKIDDEETQNYNQQG--VGLGLLISNMLS
 |..|..||. ||..||.|.|.  |.| .  .    . ......|.|.|| .       .. ..| .|.. |.     .. .|   |||| |.....
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD-SR-RKYGGGLTGLGLYICRRIV
Kinase 11754.AA HATPase_c 1009-1161 17 1.9e-20 75.16 SMART 1-130 (130) Show / Hide 
Range on Protein: 1009-1161
Range on HMM: 1-130/130
Sequence Identity: 17% (32 aa)

SDQERIKQVIINLISNALKFTHN--------------GRIFIQSEYNSLNSIQVSIKDTGIGIEK------SKLKQLFKAFGKIDDEE------TQNYNQ
 |..|..||..||..||.|.|.               ||| .  .       .....|.|.|| .       .....| .|.. ||..       .... 
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

QG--VGLGLLISNMLSIQL-----AKPPTNENMSSQINQNINSNSIMNINQSNQSIQQNNKQDKGLKVESEKGIGSTFTLTITDHN
.|   |||| |..... |.     .                                                  .|||.|.    
GGGLTGLGLSICKRIVEQHGGTIWVE-------------------------------------------------TTFTFTLPLER
Kinase 11754.AA HATPase_c 1141-1160 50 1.988722 3.73 Pfam 101-120 (120) Show / Hide 
Range on Protein: 1141-1160
Range on HMM: 101-120/120
Sequence Identity: 50% (10 aa)

LKVESEKGIGSTFTLTITDH
. |||| | |.|||.|.   
IWVESEPGGGTTFTFTLPLE
Response_reg 11754.AA Response_reg 1449-1490 27 3e-06 25.16 Pfam 1-43 (115) Show / Hide 
Range on Protein: 1449-1490
Range on HMM: 1-43/115
Sequence Identity: 27% (12 aa)

ILIVDDNVFCCEALKNIIEKRFGI-SCMICYSATKAIEIVKQR
.|||||.   .|.|..|.|.. |. ..  ....  |.|.....
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEH
Response_reg 11754.AA Response_reg 1560-1579 42 0.088418 8.94 Pfam 48-68 (115) Show / Hide 
Range on Protein: 1560-1579
Range on HMM: 48-68/115
Sequence Identity: 42% (9 aa)

IFLDINMPDVSGFEGLYQI-K
|..|||||...|.| . .| .
IIMDINMPGMDGLELCRRIRR