Gene 10868 (Tetrahymena)

10868

Species: Tetrahymena
Alias: PreTt10868, 151, TTHERM_00717720, 114.m00103, 3827.m00946, 10868
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
10868.AA Protein None 1206 None Fasta, JSON
10868.kin_dom Protein Kinase Domain None 121 None Fasta, JSON
10868.NA RNA None 3621 None Fasta, JSON

Protein domain

Protein domains of 10868.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 10868.AA HisKA 514-582 23 6.5e-11 43.5 SMART 1-89 (89) Show / Hide 
Range on Protein: 514-582
Range on HMM: 1-89/89
Sequence Identity: 23% (21 aa)

EKMKIFGSLSHELRTPLNCSISMLEVLKDEM--------QEINPQYI------------TDYLNPALFSNKLLLNQINDILDFVQMDKG
.| . . ..||||||||.  . ..|.|.|..        .. .|. .             .||. .. . . ....|||.||. ... |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA 10868.AA HisKA 514-582 31 1e-10 40.33 Pfam 1-69 (69) Show / Hide 
Range on Protein: 514-582
Range on HMM: 1-69/69
Sequence Identity: 31% (22 aa)

EKMKIFGSLSHELRTPLNCSISMLEVLKDEMQEINPQY-ITDYLNPALFSNKLLLNQINDILDFVQMDKG
.| . . ..||||||||.  . ..|.|.|  .. .|.  . .||. .. . . ....|||.||| ... |
AKRQFLANMSHELRTPLTAIRGYAELLQD-YTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
Kinase 10868.AA HisK 629-749 34 2.2e-60 206.91 In-house 1-164 (164) Show / Hide 
Range on Protein: 629-749
Range on HMM: 1-164/164
Sequence Identity: 34% (56 aa)

SDPNRIRQILLNFLSNSLKFTKQG------YIEINFSNFD--------------------------NGVYKIAVQDTGIGIKPENLKEIFQFCAKI----
||||||.|||.|..||.||||..|      ||.|......                          .....| |||||.|...|..|.||... .|    
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----NYSNKDELLNSQGCGLGLYISNSIAKGLVKNDK--LNSGVSVESDYGKGSVFSFLVQDQ
     .........|..||||||.|.|..|||| ...    | | .|.|..|||| |||.....
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 10868.AA HATPase_c 629-749 26 6e-19 68.17 Pfam 1-120 (120) Show / Hide 
Range on Protein: 629-749
Range on HMM: 1-120/120
Sequence Identity: 26% (36 aa)

SDPNRIRQILLNFLSNSLKFTKQ-GYIEINFSNFDNGVYKIAVQDTGIGIKP------ENLKEIFQ-------FCAKINYSNKDELLNSQG--CGLGLYI
 ||.|..|...|...|..|.|.. | |..  .  | .   | |.|.|.|| |      |..  ||.                     ...|   ||||||
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD---------SR-RKYGGGLTGLGLYI

SNSIAKGLVKNDKLNSGVSVESDYGKGSVFSFLVQDQ
.. |..       ..  ..|||  |.|..|.| .  .
CRRIVEQ------HGGTIWVESEPGGGTTFTFTLPLE
Kinase 10868.AA HATPase_c 629-750 18 1.3e-15 59.14 SMART 1-130 (130) Show / Hide 
Range on Protein: 629-750
Range on HMM: 1-130/130
Sequence Identity: 18% (31 aa)

SDPNRIRQILLNFLSNSLKFTKQ--------------GYIEINFSNFDNGVYKIAVQDTGIGIKPENLKEIFQFCAKINYSNKDELLN------------
 ||.|.||.|.| |.|..|.|..              | |..  .        | |.|.|.|| || . .          |  ... .            
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMH-K----------SI-EDIPRIFEPFYRTDDSP

-----------SQG--CGLGLYISNSIAKGL---VKNDKLNSGVSVESDYGKGSVFSFLVQDQN
           ..|   ||||.|...|.. .   .. .               ..|.| .  . 
SRMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGTIWVE---------------TTFTFTLPLER
REC 10868.AA REC 1074-1198 20 1.4e-18 68.92 SMART 1-150 (150) Show / Hide 
Range on Protein: 1074-1198
Range on HMM: 1-150/150
Sequence Identity: 20% (33 aa)

PQILIIDDN----QFNIYALS------KTIETFQFQ--------THSISDSL-------EVLDYVKDIFHQNCCLY------PKIIFMDIEMP-------
. |||.||.    . .  .|.      .. |   ..         ..  |         | |....   ...          | .|.|||.||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

FKNGYQLSVEVNQFYNNVQLKQLPVIIACTAYVGQEDNQKAIQAGMSDFINKPLLKNAFQQLI
  .|..|  ..              ||..||. . || ..|..||. |.| ||   . ... |
GMDGIELCRRIR------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 10868.AA Response_reg 1076-1199 27 1.1e-11 44.41 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1076-1199
Range on HMM: 1-115/115
Sequence Identity: 27% (35 aa)

ILIIDDNQFNIYALSKTIE-TFQF-QTHSISDSLEVLDYVKDIFHQNCCLYPKIIFMDIEMPFKNGYQLSVEV-NQFYNNVQLKQLPVIIACTAYVGQED
.||.||.. .  .| . .|   ..  . . .|  |.|....          | .|.|||.||  .|..|  .   | .   |    . ||.|||.   .|
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-------PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ----TPIIMCTAHGDEDD

NQKAIQAGMSDFINKPLLKNAFQQLIL
 ..|.|||. |.| ||  ...  . | 
AVEALQAGANDYITKPFDPDELHAAIR