Gene 10844 (Tetrahymena)

10844

Species: Tetrahymena
Alias: 10844, 154, TTHERM_00717460, PreTt10844, 3827.m00924, 114.m00079
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
10844.AA Protein None 1540 None Fasta, JSON
10844.kin_dom Protein Kinase Domain None 47 None Fasta, JSON
10844.NA RNA None 4623 None Fasta, JSON

Protein domain

Protein domains of 10844.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 10844.AA HisKA 852-920 32 6.8e-12 44.44 Pfam 1-69 (69) Show / Hide 
Range on Protein: 852-920
Range on HMM: 1-69/69
Sequence Identity: 32% (23 aa)

DKMKLFASLSHELRTPLNCSISMLEVLKD--EMSVNNQRYIDEYLNPALFSNKLLLNQINDILDFVQMDSG
 | ...|..||||||||.  . ..|.|.|  ...   .  . |||. .. . . ....|||.||| ....|
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQM--RREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 10844.AA HisKA 852-920 24 1.8e-11 45.36 SMART 1-89 (89) Show / Hide 
Range on Protein: 852-920
Range on HMM: 1-89/89
Sequence Identity: 24% (22 aa)

DKMKLFASLSHELRTPLNCSISMLEVLKDEM--------SVNNQRYI------------DEYLNPALFSNKLLLNQINDILDFVQMDSG
 | ...|..||||||||.  . ..|.|.|..        .  .   .             |||. .. . . ....|||.||. ....|
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 10844.AA HisK 954-1043 33 5.8e-42 145.74 In-house 1-164 (164) Show / Hide 
Range on Protein: 954-1043
Range on HMM: 1-164/164
Sequence Identity: 33% (55 aa)

SDPNRIRQILLNFLSNALKFTVKG------YIEIGINPLG--------------------------KNLYEIYVKDTGC---------------------
||||||.|||.|..||||||| ||      ||.| ..                             |||..|.|.||||                     
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-------------------GLGLTISNSIANGLVSNNI--NEKGIKVQSEYGKGSTFSIVIQDM
                   ||||||.|..| || ....  . .||.||||.|||||||..|.. 
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 10844.AA HATPase_c 954-1000 31 8e-10 36.42 Pfam 1-47 (120) Show / Hide 
Range on Protein: 954-1000
Range on HMM: 1-47/120
Sequence Identity: 31% (15 aa)

SDPNRIRQILLNFLSNALKFTVK-GYIEIGINPLGKNLYEIYVKDTGC
 ||.|..|...|...||.|.| . | |.. . . . .  .| |.|.|.
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGP
Kinase 10844.AA HATPase_c 954-1044 18 1e-08 36.22 SMART 1-130 (130) Show / Hide 
Range on Protein: 954-1044
Range on HMM: 1-130/130
Sequence Identity: 18% (28 aa)

SDPNRIRQILLNFLSNALKFTVK--------------GYIEIGINPLGKNLYEIYVKDTGC---------------------------------------
 ||.|.||.|.| |.||.|.| .              | |.. ..       .| |.|.|.                                       
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

-G----LGLTISNSIANGLVSNNINEKGIKVQSEYGKGSTFSIVIQDMD
 |    |||.|...|.. .         |.|.      .||.. .    
GGGLTGLGLSICKRIVEQHGGT------IWVE------TTFTFTLPLER
Kinase 10844.AA HATPase_c 1001-1043 32 0.040906 9.6 Pfam 84-120 (120) Show / Hide 
Range on Protein: 1001-1043
Range on HMM: 84-120/120
Sequence Identity: 32% (14 aa)

GLGLTISNSIANGLVSNNINEKGIKVQSEYGKGSTFSIVIQDM
||||.|.. |.  .         | |.|| |.|.||.. .   
GLGLYICRRIVEQHGGT------IWVESEPGGGTTFTFTLPLE
REC 10844.AA REC 1408-1532 22 9e-23 82.9 SMART 1-150 (150) Show / Hide 
Range on Protein: 1408-1532
Range on HMM: 1-150/150
Sequence Identity: 22% (36 aa)

PQILIVDDN----QFNLYALS------KVAEQYHFR--------YTTASDGN-------LALQEIENIYQFNCCKA------PKIIFMDIEMP-------
. ||||||.    . .. .|.      .  |.  ..         ..| ||         ||. ...  ...          | .|.|||.||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

FKDGYETAQEIIQFYKNVNLKQLPILIACTAYVGQEDQNRFFQVGMVDFINKPILKNAFQQLI
  ||.|....|               |..||. . ||  | ...|..|.| ||.  . ... |
GMDGIELCRRIR------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 10844.AA Response_reg 1410-1533 28 4.4e-13 49.44 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1410-1533
Range on HMM: 1-115/115
Sequence Identity: 28% (36 aa)

ILIVDDNQFNLYALSKVAE-QYHF-RYTTASDGNLALQEIENIYQFNCCKAPKIIFMDIEMPFKDGYETAQEI-IQFY-KNVNLKQLPILIACTAYVGQE
.|||||.. .. .| .  | .. . . ..|.||  ||. ...         | .|.|||.||  ||.|....|  | .  .      .  |.|||.   .
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-------PDLIIMDINMPGMDGLELCRRIRRQHPHPQ------TPIIMCTAHGDED

DQNRFFQVGMVDFINKPILKNAFQQLII
|  . .|.|..|.| ||. ...  . | 
DAVEALQAGANDYITKPFDPDELHAAIR