Gene 1075 (Tetrahymena)

1075

Species: Tetrahymena
Alias: 336, 1075, 100.m00136, TTHERM_00670510, 3731.m00046, PreTt01075
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
1075.AA Protein None 1662 None Fasta, JSON
1075.kin_dom Protein Kinase Domain None 118 None Fasta, JSON
1075.NA RNA None 4989 None Fasta, JSON

Protein domain

Protein domains of 1075.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 1075.AA HisKA 597-664 28 3e-06 24.62 Pfam 1-69 (69) Show / Hide 
Range on Protein: 597-664
Range on HMM: 1-69/69
Sequence Identity: 28% (20 aa)

YKNRLISSFSHELRTPLNSSMGFLQSGLLDETISETA-KNIYLLPAYQALKLQYYFISDILDFSQILAK
 |...... ||||||||.. .|...  . ... ..      ||  ......     |.|.||||.| | 
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 1075.AA HisKA 597-664 21 3e-05 23.44 SMART 1-89 (89) Show / Hide 
Range on Protein: 597-664
Range on HMM: 1-89/89
Sequence Identity: 21% (19 aa)

YKNRLISSFSHELRTPLNSSMGFLQSGLL---------DETISETAK------------NIYLLPAYQALKLQYYFISDILDFSQILAK
 |...... ||||||||.. .|...  .          . . ..                 ||  ......     |.|.||.|.| | 
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 1075.AA HisK 713-830 26 1.1e-36 128.16 In-house 1-164 (164) Show / Hide 
Range on Protein: 713-830
Range on HMM: 1-164/164
Sequence Identity: 26% (43 aa)

TDYDRLMQVLVNLINNSLRFTLKG------GVTVKI---------------IPTLQNN-----------LCIHVIDTGEGMNVMQFEQIKQKLSQFGT--
.|. |..|.|.||| |.| || ||       ...|.               | ..|.|           ..|.|.||| ||.  | ..|....... .  
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----TGIPITE---TQHTGFGLTISQIIVSILASE----SNQDLELKKTFGGGCTFSFCIENI
     | .   .   ..  |.||||..... .| .|     |. .... . | |.||||.|.| 
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 1075.AA HATPase_c 713-830 25 1e-17 63.86 Pfam 1-120 (120) Show / Hide 
Range on Protein: 713-830
Range on HMM: 1-120/120
Sequence Identity: 25% (32 aa)

TDYDRLMQVLVNLINNSLRFTLK-GGVTVKIIPTLQNNLCIHVIDTGEGMNV------MQFEQIKQKLSQFGTTGIPITETQH--TGFGLTISQIIVSIL
.| |||.||. ||. |....| . | .||.. ..  ....| |.|.| |. .       . ..| ..  ...       ....  ||.||.|.. ||  .
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD-SR-RKYGGGLTGLGLYICRRIVEQH

ASESNQDLELKKTFGGGCTFSFCIENI
  .    ...  . |||.||.| .   
GGT----IWVESEPGGGTTFTFTLPLE
Kinase 1075.AA HATPase_c 713-831 22 2.6e-14 54.77 SMART 1-130 (130) Show / Hide 
Range on Protein: 713-831
Range on HMM: 1-130/130
Sequence Identity: 22% (33 aa)

TDYDRLMQVLVNLINNSLRFTLK--------------GGVTVKIIPTLQNNLCIHVIDTGEGMNV----MQFEQIKQKLSQFGTTGI---------PITE
.| |||.||| ||..|....| .              | .||..        .| |.|.| |.         |.|.. .  |..|.            ..
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSI-EDIPRIFEPFYRTDDSPSRMCPDSRSRK

TQH--TGFGLTISQIIVSILASESNQDLELKKTFGGGCTFSFCIENIL
..   || ||.|.. ||  .  .    ...       .||.| .   .
YGGGLTGLGLSICKRIVEQHGGT----IWVE------TTFTFTLPLER
REC 1075.AA REC 1514-1645 21 3.3e-25 90.97 SMART 1-150 (150) Show / Hide 
Range on Protein: 1514-1645
Range on HMM: 1-150/150
Sequence Identity: 21% (36 aa)

RRILCVDDE----VFNIQVLM------LLFQKLDYK--------IEKAFNGK-------DAIAIFIQFYNQKQKYQCESPNCTVFKAIILDCNMP-----
 |||.|||.      . ..|       .|..|..|         .. | .|.       .|.... ..  .|   . .. . . .  ||.|..||     
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKED-ATTD-QSEPPDLIIMDIMMPGDPFE

--IMNGWDCAKELRNLMNQKKLPSIPIIALTAYVAQQSYNQCIESGMDDVLNKPINIEVLKYKV
   |.|.. ....|           |||.|||.   .   ...|.|.|| . ||...| |  ..
DGGMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 1075.AA Response_reg 1516-1646 22 1.5e-17 65.38 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1516-1646
Range on HMM: 1-115/115
Sequence Identity: 22% (30 aa)

ILCVDDEVFNIQVLMLLFQ-KLDY-KIEKAFNGKDAIAIFIQFYNQKQKYQCESPNCTVFKAIILDCNMPIMNGWDCAKEL-RNLMNQKKLPSIPIIALT
.|.|||.  . ..|  ... | .| ... | .|..|....     |...          .  ||.|.||| |.| . .... |..  . .   .|||..|
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWW-----QEHH----------PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ---TPIIMCT

AYVAQQSYNQCIESGMDDVLNKPINIEVLKYKVE
|.   .   .... |..| . ||.... |. ...
AHGDEDDAVEALQAGANDYITKPFDPDELHAAIR