Gene 10472 (Tetrahymena)

10472

Species: Tetrahymena
Alias: PreTt10472, 246, 3810.m02035, 10472, TTHERM_00569440, 76.m00174
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
10472.AA Protein None 1867 None Fasta, JSON
10472.kin_dom Protein Kinase Domain None 111 None Fasta, JSON
10472.NA RNA None 5604 None Fasta, JSON

Protein domain

Protein domains of 10472.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 10472.AA HisKA 687-752 13 5.3e-05 21.24 SMART 1-89 (89) Show / Hide 
Range on Protein: 687-752
Range on HMM: 1-89/89
Sequence Identity: 13% (12 aa)

FQTKVLKSISHEFGTPLNCAINMLKMCSLKVE-------KELN----------------SNYILPALSSIRILKFSCSDFIDYAKIQFN
 ... | ..|||. |||.  . .....  ...        .|.                  |.  ...... .    .|. |...|. .
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA 10472.AA HisKA 687-752 17 0.000451 17.18 Pfam 1-69 (69) Show / Hide 
Range on Protein: 687-752
Range on HMM: 1-69/69
Sequence Identity: 17% (12 aa)

FQTKVLKSISHEFGTPLNCAINMLKMCSL--KVEKEL-NSNYILPALSSIRILKFSCSDFIDYAKIQFN
 ... | ..|||. |||.  . .....    .   |     |.  ...... .    .|. |...|. .
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
Kinase 10472.AA HisK 804-914 35 9.2e-47 161.68 In-house 1-164 (164) Show / Hide 
Range on Protein: 804-914
Range on HMM: 1-164/164
Sequence Identity: 35% (58 aa)

SDPSRIMQVIFNLLTNALKFTQKG------FIKIKATCIS--------------------------EDEIEISVQDSGIGIQVEQQDNLFERKT------
|||.||.|...||..|||||||||      .||||...|.                          .. |.|||||.|.|.  ||| ..|.         
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

--------IKNK--KQETSGLGLIISNALAQRLSYQG-----QGLNLQSKVGEGSLFSFNININ
         .||  .|.  ||||.|.| ||. |. ..     .|. .||.||.|| ||| |. |
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 10472.AA HATPase_c 804-914 28 1e-22 81.33 Pfam 1-120 (120) Show / Hide 
Range on Protein: 804-914
Range on HMM: 1-120/120
Sequence Identity: 28% (35 aa)

SDPSRIMQVIFNLLTNALKFTQK-GFIKIKATCISEDEIEISVQDSGIGIQV------EQQDNLFE----RKT-IKNKKQET--SGLGLIISNALAQRLS
 || |..||. ||..||.|.|.. | |.....    |...|.|.|.|.|| .      |.....||     .      | .   .|||| |.......  
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQ--

YQGQGLNLQSKVGEGSLFSFNININ
..|. . ..|..|.|. |.| .   
HGGT-IWVESEPGGGTTFTFTLPLE
Kinase 10472.AA HATPase_c 804-915 20 2.8e-18 67.95 SMART 1-130 (130) Show / Hide 
Range on Protein: 804-915
Range on HMM: 1-130/130
Sequence Identity: 20% (31 aa)

SDPSRIMQVIFNLLTNALKFTQK--------------GFIKIKATCISEDEIEISVQDSGIGIQV------EQQDNLFERKTI------------KNKKQ
 || |..||. |||.||.|.|..              | |....        .|.|.|.|.||        |.....||.               .. | 
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

ET--SGLGLIISNALAQRL----SYQGQGLNLQSKVGEGSLFSFNININC
.   .|||| |........    ...             . |.| . .  
GGGLTGLGLSICKRIVEQHGGTIWVE-------------TTFTFTLPLER
REC 10472.AA REC 1699-1822 23 1.2e-18 69.17 SMART 1-150 (150) Show / Hide 
Range on Protein: 1699-1822
Range on HMM: 1-150/150
Sequence Identity: 23% (38 aa)

PDILIVDDT----QMNRHTLR-----LMIQSKLPFI--------IDEATNGQ-------EAVDKVEQLI------NTQNHCLTYKMIFMDIDMP------
. ||||||     ...|..||      .. .|. .         .||| .|.       ||.......        |      .  |.||| ||      
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED

-KMNGYEATYKINELFKKNDIFCPIIAHTAFDRSEVQEEMNQCNMIDYAGKPIST-AIIEQL
 .|.|.|.. .|           |||. ||.|  |  ..  .  . ||  ||..   ... .
GGMDGIELCRRIR----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 10472.AA Response_reg 1701-1793 30 7.4e-13 48.62 Pfam 1-84 (115) Show / Hide 
Range on Protein: 1701-1793
Range on HMM: 1-84/115
Sequence Identity: 30% (29 aa)

ILIVDDTQMNRHTLRLMIQSKLPF-IIDEATNGQEAVDKVEQLINTQNHCLTYKMIFMDIDMPKMNGYEATYKI-NELFKKNDIFCPIIAHTAFD
.||||| . .|  || ... |  . ...||..|.||.......         . .|.|||.||.|.|.|.. .|  ..  . .  .|||. ||..
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH--------PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ--TPIIMCTAHG