Gene 17637 (Tetrahymena)

17637

Species: Tetrahymena
Alias: 1052, 17637, TTHERM_01020700, PreTt17637, 200.m00050, 3756.m00246
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: ABC1
Subfamily: ABC1-B

Sequence

Name Sequence Type Origin Length Description Download
17637.AA Protein None 747 None Fasta, JSON
17637.kin_dom Protein Kinase Domain None 118 None Fasta, JSON
17637.NA RNA None 2244 None Fasta, JSON

Protein domain

Protein domains of 17637.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 17637.AA ABC1-B 135-252 43 1e-76 261.15 In-house 1-125 (125) Show / Hide 
Range on Protein: 135-252
Range on HMM: 1-125/125
Sequence Identity: 43% (55 aa)

SSLRKPIDEVFSEFNPKPLKSASIAQVHEAVLKETGERVAVKVMHDWLQESSKGDLKVIGLFVDIGELLFP------EFKFKWFSEELNQILPQELNFLD
..|. .|..|||||..||...||.||||.|.|.. ||.|||||.|.||......|.....|||......||      ||.|.||..|....|||||.|..
KDLG-NIEDVFSEFDQKPIAAASLAQVHRAKLHD-GETVAVKVQHPWLRKQFHYDMMMMELFVKVCDWFFPKSPDFKEFPFMWFHDEIQKNLPQELDFYN

EVKNSERARQILK---DKPNIYVPINH
|..|.|..||..|   .....|||..|
EARNAEKCRQMFKKFKHFDFLYVPRIH
Kinase 17637.AA ABC1 135-252 39 7.8e-67 228.35 In-house 1-123 (123) Show / Hide 
Range on Protein: 135-252
Range on HMM: 1-123/123
Sequence Identity: 39% (49 aa)

SSLRKPIDEVFSEFNPKPLKSASIAQVHEAVLKETGERVAVKVMHDWLQESSKGDLKVIGLFVDIGELLFP-----EFKFKWFSEELNQILPQELNFLDE
..|. ....|||||..||...|||||||.|.||. |..|||||.|....|....|.... ..|......||     .|...||..|....||.|..|..|
QDLG-NWEDVFSEFDEKPFAAASIAQVHRAKLKD-GQTVAVKVQHPGVREQIHYDINNMEMVVKMCDWFFPGPDFKWFFLMWFVDEFQKELPWECDFNNE

VKNSERARQILK--DKPNIYVPINH
..|.|..||..|  ..|..|||..|
ARNAEKCRQLFKKFHWPFFYVPRIH
Kinase 17637.AA ABC1 135-252 35 9.1e-37 125.91 Pfam 1-126 (126) Show / Hide 
Range on Protein: 135-252
Range on HMM: 1-126/126
Sequence Identity: 35% (45 aa)

SSLRKPIDEVFSEFNPKPLKSASIAQVHEAVLKETGERVAVKVMHDWLQESSKGDLKVIGLFVDIGELLFPE-----FKFKWFSEELNQILPQELNFLDE
..| .|..|.|.||...|. .||||||| |.||  || ||||| |  ...... |.. . ..... ...||.     |.. |  .|. . ||.||... |
EELGCPWEEIFQEFDEEPIAAASIAQVHRARLKDDGEEVAVKVQHPGVKKRMMRDIYNMRWMAKWVKRFFPGYRRQRFDLMWIVDEFRKNLPWELDYRRE

VKNSERARQILKDK---PNIYVPINH
 ||.|| |. ...    |..|||  .
AKNMERFRENFRHWHRQPWVYVPKVY
Kinase 17637.AA ABC1-A 148-177 56 1.2e-07 22.77 In-house 1-29 (216) Show / Hide 
Range on Protein: 148-177
Range on HMM: 1-29/216
Sequence Identity: 56% (17 aa)

FNPKPLKSASIAQVHEAVLKETGERVAVKV
|  .|   ||| ||| ||||  | .||||.
FEEMPFACASIGQVHQAVLKD-GREVAVKI
Kinase 17637.AA ABC1-A 237-277 43 3.1e-05 14.35 In-house 89-129 (216) Show / Hide 
Range on Protein: 237-277
Range on HMM: 89-129/216
Sequence Identity: 43% (18 aa)

RQILKDKPNIYVPINHFGLCNSKIITMEFIDGFPIMDVPTL
|| ||| |  |||     .| ....||| . ||||.  . |
RQLLKDWPFFYVPHVIDEYCTDRVLTMELMYGFPIDQCQGL
Kinase 17637.AA Worm5 303-330 46 0.00016 9.61 In-house 126-153 (260) Show / Hide 
Range on Protein: 303-330
Range on HMM: 126-153/260
Sequence Identity: 46% (13 aa)

GFVHSDPHQGNLLLRKVKDPKNPHKTID
||.| | | .|..  |  .| || | ||
GFIHRDCHWQNIMFAKRITPINPCKLID
Kinase 17637.AA S_TKc 147-420 11 0.000335 -115.31 SMART 1-231 (231) Show / Hide 
Range on Protein: 147-420
Range on HMM: 1-231/231
Sequence Identity: 11% (36 aa)

EFNPKPLKSASIAQVHEAVLKETGERVAVKVMHDWLQESSKGDLKVIGLFVDIGELLFPEFKFKWFSEELNQILPQELNFLDEVKNSERARQILKDKPNI
    ... . . ..|. .. |.||..||.|...                                             ... |..  ..      . |||
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------------------------------------------EHIRREIQILKK------HHPNI

YVPINHFGLCNSKIITMEFIDG--FPIMDVPTLKREK-----FDMKKIAYTISDTFSQMIF--QNGFVHSDPHQGNLLLRKVKDPKNPHKTIDQVVLLDH
   . .|   ..  . ||..||     .|.   .. .     |.   ... .  ... . .  ..|..| |    |.|| .            .. . | 
VKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------------HIKICDF

GLYKNLSPQFRL------------SYSK--------------------LWKGIITQNEELIQKSSIELGVKEDQYPLFASMITSRTYEDLMDD--KKSVK
|| . |     .            .|.|                    ..     | .....|                    |.   |...   .|  .
GLARQL---TTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG------------------SPEAKDFIRKCLQKDPE

ERLRSPQNQE----ERDKIAI
.|.   .  .     .    .
KRPTA-EALQDEWDIKCHPWF
Kinase 17637.AA CAMK1 159-178 30 0.000651 7.19 In-house 13-35 (276) Show / Hide 
Range on Protein: 159-178
Range on HMM: 13-35/276
Sequence Identity: 30% (7 aa)

AQVHEAVLKET---GERVAVKVM
..|.... |||   |. .|.|..
SEVYLCTHKETQTNGKQYAIKCI
COQ9 17637.AA COQ9 621-699 50 2.6e-43 155.01 Pfam 1-79 (79) Show / Hide 
Range on Protein: 621-699
Range on HMM: 1-79/79
Sequence Identity: 50% (40 aa)

PKNVSTTTSNLWKIADDIWFLSGDRSYDYNYYTKRTLLLGVYASTELFMLTDKSKDFSETWKFLDRRIDEVLTAGQSIH
|.|..|  ..||..|||||...||.| |.|.||||. | .||.||||..|.|.|.|...||.|||||||.|  ...  .
PQNAPTSLKELWRTADDIWHYAGDTSTDFNWYTKRATLSAVYSSTELYWLQDDSPDHEDTWAFLDRRIDDVMQFEKMKA