Gene 11909 (Tetrahymena)
11909
Sequence
Protein domains of 11909.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 11909.AA | Akt | 37-302 | 50 | 4.5e-185 | 596.66 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 37-302 Range on HMM: 1-264/264 Sequence Identity: 50% (137 aa) FEFIKCIGTGSFGKVYLVKKKQTEDLY-AMKILRKDQIKNKTQLIQTKAERYILENVDSPFVVQLAYAFQSQTKLYIVMEFCQGGDIFGHMVKQPFFPEN |.|.|..| ||||||.|||||.|...| |||.|.||.| .| |. .||.||.||.....||.|.| |.||.|.|||.||..|.||..| |. ....|.|. FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED KIKFYAAEIFLALEKLHEQGIVYRD-LKPENILVSATGHIKLTDFGLSKKL-KSRDEITYSFCGTAEYMAPEIISKQGHDVASDWWSFFKYLNISKGAVL ...||.|||.||.| ||...|.||| |||||||....|||.||||||.|. ......|..||||.||.||||....||. |.|||. | |.|. RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWG-------SLGCVM YEMLHGAPPFYEKNKERMMDKLVNQDVVIK--DKYSKECQSLLRGLLTRDKTKRLGNGPEGTQEIRNHPFF |||..|.||||......|..| ||.| .. |..|.||..|..|||..|..||||.||...|||..||.| YEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
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Kinase | 11909.AA | AGC | 37-302 | 34 | 1.3e-177 | 463.92 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 37-302 Range on HMM: 1-395/395 Sequence Identity: 34% (138 aa) FEFIKCIGTGSFGKVYLVKKK------QTEDLYAMKILRKDQ---IKNKTQLIQTKAE------------RYILENVD----------SPFVVQ-LAYAF |||.|.||.|||||||||.|| .|...||||.|.|. ||.| .. .|..| | |||... .||.|. | |.| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QSQTK--LYIVMEFCQ---------GG-DIFGHMV---KQPFFPENKIKFYAAE-------IFLALEKLHE-QGIVYRD-LKPENILVSATGHIKLTDFG |.... ||.|||... || . | |. |. |.|. ..||||| | |||| ||. .||..|| ||||||| . ||||||||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG LSKKLKSRDEI--------------------------------------------------TYSFCG--TAEYMAPEIISKQGHDVASDWWSFFKYLNIS |.|......|. |..||| |.|||||||. .. | ||||| . LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSF------G KGAVLYEMLHGAPPFYEKN----------KERMMDKLV------NQDVVIK----------DKYSKECQSLLRGLLTRDKTKRLGNGPE-----GTQEIR |...|||| | |||| .| .. |..| |..| . .. |.|...|...||..| .||||.|.. |..||. LGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIK NHPFF |||.| NHPWF |
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Kinase | 11909.AA | RSK | 37-302 | 44 | 1.1e-167 | 563.39 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 37-302 Range on HMM: 1-271/271 Sequence Identity: 44% (124 aa) FEFIKCIGTGSFGKVYLVKKK---QTEDLYAMKILRKDQIKNKTQLIQTKAERYILENVDSPFVVQLAYAFQSQTKLYIVMEFCQGGDIFGHMVKQPFFP .|...|||.|||.|||..||. .|...|||||..|.....|.. .....||.||.....||.|.|.|.||...|.|..|.|..|||.|....||..|. YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS ENKIKFYAAEIFLALEKLHEQGIVYRDLKPENILVSAT----GHIKLTDFGLSKKLKSRDEITYSFCGTAEYMAPEIISKQGHDVASDWWSFFKYLNISK |...|||.|||.||.|.||.||||.|||||||||.... ||||..|||..|.|.........||.||.|||||....||||.|.||||| EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSF-------- GAVLYEMLHGAPPFYEKNKERMMDKLVNQDVVI-------KDKYSKECQSLLRGLLTRDKTKRLGNGPEGTQEIRNHPFF |...||||.|..||..|.....|.......... .|..|.|...|||..|.||...|||.||.|...|..||.| GVLMYEMLTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF |
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Kinase | 11909.AA | SGK | 37-302 | 46 | 1.1e-140 | 437.49 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 37-302 Range on HMM: 1-283/283 Sequence Identity: 46% (135 aa) FEFIKCIGTGSFGKVYLVKKKQT------------------EDLYAMKILRKDQIK-------NKTQLIQTKAER-YILENVDSPFVVQLAYAFQSQTKL |.|.| || |||||||.||.|.. ...||||.|.|..| .| . ..||| || |. .|| |.| |||| ..|| FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL YIVMEFCQGGDIFGHMVKQPFFPENKIKFYAAEIFLALEKLHEQGIVYRDLKPENILVSATGHIKLTDFGLSK-KLKSRDEITYSFCGTAEYMAPEIISK | ||.. .||. | |. . ||| . .|||||| .||| ||.| |.|||||||||| . ||..||||||.| . | |. | .|||| ||.|||.. | YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDT-TFTFCGTPEYLAPEVLRK QGHDVASDWWSFFKYLNISKGAVLYEMLHGAPPFYEKNKERMMDKLVNQDVVIKDKYSKECQSLLRGLLTRDKTKRLGNGPEGTQEIRNHPFF |.|| . |||. |.|||||..|.|||| .||. | |. ||. |. | .. .|. |||..|..|||| .. ||.||||| QPHDRTVDWWCL--------GCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTK-RDFMEIKNHPFF |
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Kinase | 11909.AA | AktR | 37-302 | 45 | 1.9e-127 | 429.73 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 37-302 Range on HMM: 1-268/268 Sequence Identity: 45% (126 aa) FEFIKCIGTGSFGKVYLVKKK-QTEDLYAMKILRKDQIKNKTQLIQTKAERYILE-NVDSPFVVQLAYAFQSQTKLYIVMEFCQGGDIFGHMVKQPFFPE |...||.| | |||||||.|| .. ..||||...| |....| .| ||.|.| .. || |.| |.||...||...||.|.||..| | |. .| | FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE NKIKFYAAEIFLALEKLHEQ-GIVYRDLKPENILVSATGHIKLTDFGLSK--KLKSRDEITYSFCGTAEYMAPEIISK-QGHDVASDWWSFFKYLNISKG ....||.|.| |||| ||.. |.|||||||||| ||.|.||||||| . ...||..|||||| ||||||.| | .||. ..|||.| | EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAF--------G AVLYEMLHGAPPFYEKNKERMMDKLVNQD-VVIKDK--YSKECQSLLR-GLLTRDKTKRLGNGPEGTQEIRNHPFF ...|||. | |||| ||...| .| ... . ... |..|..|. .|| .. .|||| . .|..||..||.| IFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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Kinase | 11909.AA | RSK | 40-302 | 43 | 2.7e-118 | 399.32 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 40-302 Range on HMM: 1-278/278 Sequence Identity: 43% (123 aa) IKCIGTGSFGKVYLVKKK---QTEDLYAMKILRKDQIKNKTQ-LIQTKAERYILENVD-SPFVVQLAYAFQSQTKLYIVMEFCQGGDIFGHMVKQPF--- .| |.|..|||.|..|. .|. .||||.|.| |... . |..|| ||| . .||.|.| |||| ..|||..||.| ||. | | |. . LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC FPENKIKFYAAEIFLALEKLHEQGIVYRDLKPENILVSA---TGHIKLTDFGLSKKLKSR-DEITYSFCGTAEYMAPEIIS---KQG-HDVASDWWSFFK | |. .||.||| ||.| ||.|||..||||||||| |||||||||..|... . . |..||.|.||||||.. .|| || | ||||. FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSL-- YLNISKGAVLYEMLHGAPPFYE---KNKERMMDKLVNQD--VVIK--DKYSKECQSLLRGLLTRDKTKRLGNGPEGTQEIRNHPFF |...|||| |.|||. .|.. |.. . . . .. .. |.|...|.|..|.|| |||| ||....||..||.| ------GVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | 11909.AA | p70 | 37-302 | 38 | 5.5e-106 | 358.41 | In-house | 1-299 (299) | Show / Hide |
Range on Protein: 37-302 Range on HMM: 1-299/299 Sequence Identity: 38% (118 aa) FEFIKCIGTGSFGKVYLVKKKQ---TEDLYAMKILRKDQI-KNKTQLIQTK-------------------------AERYILENVDSPFVVQLAYAFQSQ || .| .| | .|||..|.| . | .|||| ||| .| | . . |. ||| ||| | .||.. |.|||| FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN TKLYIVMEFCQGGDIFGHMVKQPFFPENKIKFYAAEIFLALEKLHEQGIVYRDLKPENILVSATGHIKLTDFGLSKKLKSRDEI----------TYSFCG ||| . |. || | | .. ..|. .||..|| .||| ||..||.||||||||.. .. ||..||||||.|. ... |..||| GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG TAEYMAPEIISKQGHDVASDWWSFFKYLNISKGAVLYEMLHGAPPFYEKNKERMMDKLVNQD--VVIKDKYSKECQSLLRGLLTRDKTKRLGNGPEGTQE | |||||||... ||. | |||| |. .| || |.||| |. .|| . . . ..| |.. || |. |.|.| ||| .. TIEYMAPEILMRCGHNHAVDWWSL--------GCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAAD IRNHPFF |. |||| IQEHPFF |
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Kinase | 11909.AA | RSK-Unclassified | 37-302 | 40 | 1.9e-102 | 322.69 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 37-302 Range on HMM: 1-283/283 Sequence Identity: 40% (118 aa) FEFIKCIGTGSFGKVYLVKKKQTEDLYAMKILRKDQI--KNKTQLIQTKAERYILENVDSPFVVQLAYAFQSQTKLYIVMEFCQGGDIFGHMV--KQPFF |. .. || |.|||||||.||.|. .||||.| |... .||.. . | |. |. . ||.|.| ..||.| .|| .||.| |||.| |. |. | FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMT--EQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCF PENKIKFYAAEIFLALEKLHEQGIVYRDLKPENILVSATGHIKLTDFGLSKKL--------K-------------SRDEITYSFCGTAEYMAPEIISKQG |....|||.|. .||| || ....||||||.||. ||..||||.||.. | . | ||||| ||.|||.| | CEDDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCG HDVASDWWSFFKYLNISKGAVLYEMLHGAPPFYEKNKERMMDKLVNQDVVIK--DKYSKECQSLLRGLLTRDKTKRLGNGPEG-TQEIRNHPFF | | ||| | |.|||| | ||.| ||. . ..| . |..|..|.. ||.| |||| . | ..|. |||| HTKAVDWWTL--------GIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCK-MGDADDIKRHPFF |
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Kinase | 11909.AA | PKA | 37-302 | 42 | 1.3e-101 | 343.88 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 37-302 Range on HMM: 1-263/263 Sequence Identity: 42% (116 aa) FEFIKCIGTGSFGKVYLVKKKQTEDLYAMKILRKDQIKNKTQLIQTKAERYILENVDSPFVV-QLAYAFQSQTKLYIVMEFCQGGDIFGHMVKQPFFPEN ||.|. .||||||.|.|...|.... ||||.|.|..|. | .. |. || |...||.| .. . || ..|| |||...||..| .. | |.. FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP KIKFYAA-EIFLALEKLHEQGIVYRDLKPENILVSATGHIKLTDFGLSKKLKSRDEITYSFCGTAEYMAPEIISKQ-GHDVASDWWSFFKYLNISKGAVL ||||| .|.|||| || | |.|||||||||| ||||.|||| .||...| |.. ||| ||.|||||. || . |||.. | . HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDDR---TWTLCGTPEYLAPEIIQSKNGHGKSVDWWAL--------GILI YEMLHGAPPFYEK--NKERMMDKLVNQDVVIKDKYSKEC---QSLLRGLLTRDKTKRLGNGPEGTQEIRNHPFF |||| | ||||.. .. . .| .| .. ... .|.. ||..| |||.|| .|.. |.||..| YEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF |
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Kinase | 11909.AA | S_TKc | 37-302 | 35 | 5.4e-101 | 342.73 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 37-302 Range on HMM: 1-231/231 Sequence Identity: 35% (99 aa) FEFIKCIGTGSFGKVYLVKKKQTEDLYAMKILRKDQIKNKTQLIQTKAERYILENVDSPFVVQLAYAFQSQTKLYIVMEFCQG--GDIFGHMVKQPF--- .|... || |.|||||....| | ..|.||.. .... |. ||.. . |..|.| ..||. ..||.|||.| | || | ...|.. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---FPENKIKFYAAEIFLALEKLHEQGIVYRDLKPENILVSATGHIKLTDFGLSKKLKSRDEITYSFCGTAEYMAPEIISKQGHDV-ASDWWSFFKYLNI ||| ..||...|..||| .|..||..|||||||||.. |||..||||...| ..|||| .|||||.. |.. ..||||. RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSC------ SKGAVLYEMLHGAPPFYEKNKERMMDKLVNQDVVIKDKYSKECQSLLRGLLTRDKTKRLGNGPEGT--QEIRNHPFF | .||||| | |||. . ..|..|.. |.|. ...|..|..| .||.. . ..|..||.| --GCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 11909.AA | Ciliate-E2-Unclassified | 37-302 | 28 | 3.4e-91 | 309.26 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 37-302 Range on HMM: 1-352/352 Sequence Identity: 28% (103 aa) FEFIKCIGTGSFGKVYLVKKKQTEDLYAMKILRKDQIKNKTQLIQ---------TKAERY-------------ILENVDSPFVVQLAYAFQSQTKLYIVM ...||.||.|.|||||....|.. .||||.. | ||... | . . .. || | ..||.| . |.||.. ..|||| YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM EFCQGGDIFGHMVKQPF-----------------FPENKIK-----FYAAEIFLALEKLHEQG-IVYRDLKPENILVSATG---HIKLTDFGLSKKLKSR |.|.||| . .. |... |.|...| ||.|.| ..||.||... |..||.||||||.. | .||..|||.|||... EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN ---------------DEITYSFCGTAEYM----APEIISKQGHD----VASDWWSFFKYLNISKGAVLYEMLHGAPPFYEKNKER--------------- ......|||| .|| |||.. .|..| ..|.||. | .||||| | .||| .|.| NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSL--------GVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRK -MMDKLVNQDVVIK--------DKYSKECQSLLRGLLTRDKTKRLGNGPEGTQEIRNHPFF . .. .... .. .. |.|.. ... || .. |.... . . ..| |||.| QLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI-TFEQILNHPWF |
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Kinase | 11909.AA | Pkinase | 37-302 | 30 | 1.2e-87 | 302.3 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 37-302 Range on HMM: 1-293/293 Sequence Identity: 30% (94 aa) FEFIKCIGTGSFGKVYLVKKKQTEDLYAMKILRKDQIKNKTQLIQTK-AERYILENVDSPFVVQLAYAFQSQTKLYIVMEFCQGG----DIFGHMV--KQ ......|| ||||.||. ..| |....|.||..|. .| . . . .. .| .|. ....|..|.| ..|.. ...|.|||.|.|| | | .. .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH PFF--PENKIKFYAAEIFLALEKLHEQGIVYRDLKPENILVSATGHI----KLTDFGLSKKL-KSRDEITYSFCGTAEYMAPEIIS-KQGHDVASDWWSF | .|. .|||. .|. .|| .|..||..|||||||||.. .||| |..||||.|.. ... ...|||| .|||||.| |... ..|.||. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC FKYLNISKGAVLYEMLHGAPPFYEK------NKERMMDKLVNQDVVIKDKYS---------------------KECQSLLRGLLTRDKTKRLGNGPEGTQ | .||||| | |||... .. |... .. .. .||.......|..| .||.. . --------GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AE EIRNHPFF .| .||.| QILQHPWF |
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Kinase | 11909.AA | TyrKc | 37-286 | 19 | 7e-13 | -14.4 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 37-286 Range on HMM: 1-280/280 Sequence Identity: 19% (59 aa) FEFIKCIGTGSFGKVYLVKKKQTEDLYAMKILRKDQIKNKTQLIQTKAERYILENV--DSPFVVQLAYAFQSQ-------TKLYIVMEFCQGGDIFGHM- ...| .| | ||.||. . | | | |..| . | |. .. . | .|.| . .| |.||||.. .|| . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR VKQPFFPENKIKFYAAEIFLALEKLHEQGIVYRDLKPENILVSATGHIKLTDFGLSKKLKSR-------DEITYSF--CGT----AEYMAPEIISKQGHD ..| .. . .. | | ||..... ||| |.||.. ...| .|||||..... | .. . .| |||| | . KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT VASDWWSFFKYLNISKGAVLYEML-HGAPPFYE-----KNKERMMDKLVNQDVVIKDKY---------SKECQSLLRGLLTR---------DKTKRL .|| ||| | ...|.. |..| .. .. .... .. . . . .. ..| .. . . . ... TKSDVWSF--------GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | 11909.AA | S_TK_X | 303-368 | 24 | 2.2e-11 | 45.06 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 303-368 Range on HMM: 1-79/79 Sequence Identity: 24% (20 aa) NNVDWDKFLR--LEVQPPYIPKVS----DKYDLRNIDNNFLKMDSKDTPGDMVGS-ALKFSKKNE---------FNGFTYER ..|||| .. |..||..||.. . |..| | | ... . ... . ... . || | |||| . RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM---LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF |
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Kinase | 11909.AA | Pkinase_C | 322-366 | 28 | 1.3e-05 | 23.11 | Pfam | 1-42 (46) | Show / Hide |
Range on Protein: 322-366 Range on HMM: 1-42/46 Sequence Identity: 28% (13 aa) KVSDKYDLRNIDNNFLKMDSKDTPGDMVGSALKFSKKNEFNGFTY .|... | .| | | ... .||| . .. . .. ..| |||| QVKSPTDTSNFDPEFTDEPPMDTP--PDWR-MSSGDQEPFRGFTY |
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Kinase | 11909.AA | Pkinase_Tyr | 37-121 | 28 | 5.8e-05 | 17.43 | Pfam | 1-93 (270) | Show / Hide |
Range on Protein: 37-121 Range on HMM: 1-93/270 Sequence Identity: 28% (27 aa) FEFIKCIGTGSFGKVYLVKKK----QTEDLYAMKILRKDQIKNKTQ--LIQTKAERYILENV-DSPFVVQLAYAFQ-SQTK--LYIVMEFCQGGD .|.| .| |.||.||. . | .|. | |.| |. . | . .| |. . . | .|.| . . .|||||....|| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGD |
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Kinase | 11909.AA | Pkinase_Tyr | 165-190 | 34 | 0.000548 | 14.13 | Pfam | 141-166 (270) | Show / Hide |
Range on Protein: 165-190 Range on HMM: 141-166/270 Sequence Identity: 34% (9 aa) NILVSATGHIKLTDFGLSKKLKSRDE |.||. ....| .||||.. . . |. NCLVTENNVVKICDFGLARDIYNDDY |