Gene 9978 (Tetrahymena)
9978
Sequence
Protein domains of 9978.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 9978.AA | MAST | 1493-1805 | 50 | 2.6e-231 | 714.96 | In-house | 1-337 (337) | Show / Hide |
Range on Protein: 1493-1805 Range on HMM: 1-337/337 Sequence Identity: 50% (171 aa) FEFIKMLGKGAYGGVYLVKKKNTNDLFAMKVIDCSGKLDKKYLETLQSEKNVFEVITGDWVVKAFYSFVH--ENYLCFVLEYMMGGDFNKILSLYT-ALD |||||...|||||.|||||.|.|||.||||||.|....||........|.|.........|||.||||.. ..|||.|.|||.|||....|. |. ... FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP QWIVEIYIAELVLAIEYLHSMDIVHRDLKPDNMLIDTTGHLKLADFGLSEVGFKTKLNKHIN-----------KTDEDPSQQGAGELV---GIN----ID .|....||||.||..|||||..||||||||||||||..||.||.|||||.|||..|...|.. ...|...|. . ... ||| .. EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTTNHYEGYFNTNIFGKNHFNEYHIQKNYQQFQQDFGINGNTNKN EANKENEFKIEIQVEGMINNEKEQQKRIVGTPDYIAPEIITGESTNNKSLDWWSMGVIMYEFLVGLPPFNADSVEE-IFDNIKN--LRMEWPEIGDINDG ......|.....|...|......|.|...|||||||||.|.|..|..|..||||||.||||||||.||||.|..|| ||.||.| ..||||.||.||. QIQQQQEQPQCQQQNEMRPHNIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDD DKISPEAYDLIKRLLNPNYKERLGAKGVKEIKEHAFF |..||||.||||.||.||.|.||||.|..|||.|.|| DCMSPEAQDLIKKLLQPNPKKRLGANGADEIKQHPFF |
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Kinase | 9978.AA | MAST | 1493-1805 | 50 | 6.1e-210 | 683.44 | In-house | 1-334 (334) | Show / Hide |
Range on Protein: 1493-1805 Range on HMM: 1-334/334 Sequence Identity: 50% (169 aa) FEFIKMLGKGAYGGVYLVKKKNTNDLFAMKVIDCSGKLDKKYLETLQSEKNVFEVITGDWVVKAFYSFVHENYLCFVLEYMMGGDFNKILSLYTALDQWI |||||...|||||.|||||.|.|||.||||||..|....|......|.|.|.........|||.||||...||||.|.|||.|||....|. |...|.|. FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM VEIYIAELVLAIEYLHSMDIVHRDLKPDNMLIDTTGHLKLADFGLSEVGFKTKLNKHIN-----------KTDEDPSQQGAGELV---GIN----IDEAN ...||||.||..|||||..||||||||||||||..|| ||.|||||.|||...||.... .......||.. ... ||| ..... AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ KENEFKIEIQVEGMINNEKEQQKRIVGTPDYIAPEIITGESTNNKSLDWWSMGVIMYEFLVGLPPFNADSVEEIFDNIKNLR---MEWPEIGDINDGDKI ...|.....|.. |......|.|...|||||||||.|.|..|..|..||||||.|||||||| |||| |..||||.||.| . .|||| |||||.... QQQEQPQCQQQN-MRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAM SPEAYDLIKRLLNPNYKERLGAK-GVKEIKEHAFF ||||.|||..||.|....||||. |..|.|.| || SPEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF |
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Kinase | 9978.AA | AGC | 1493-1805 | 30 | 5e-159 | 414.78 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 1493-1805 Range on HMM: 1-395/395 Sequence Identity: 30% (127 aa) FEFIKMLGKGAYGGVYLVKKK------NTNDLFAMKVIDCSG---KLDKKYLETLQSE------------KNVFEVITG----------DWVVK-AFYSF |||.|..|||..| ||||.|| |....||||.. . ...|. .| ..| .|..| . . ...|| .||| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF VHENY--LCFVLEYMM--------GGDFNKILSLYT-----ALDQWIVEIYIAE-------LVLAIEYLHS-MDIVHRD-LKPDNMLIDTTGHLKLADFG ... |.||.||| ||.. |.|. .| . .|.|| .|||.||||| |.|.||| |||.|.|.| ||.||.||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG LSEVGFK-----------TKLNKHINKTDEDPSQQGAGELVGINIDEANKENEFKIEIQVEGMINN----------EKEQQKRIVG--TPDYIAPEIITG |. .| . .|... ||. . | | . . | ... . . || .... . ..| ||.|.||||. LCKEGMNDGEKGQQSQSNMKFHW-HNKKY-Q-KS---------NMD--T-N---K-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-- ESTNNKSLDWWS--MGVIMYEFLVGLPPFNADSVE----------EIFDNIKNLR--MEWPEIG------DINDGDKISPEAYDLIKRLLNPNYKERLGA .|. |||| .|..|||.|.|.|||..|... |.|..|.| | ..|.. .. . ...|||| ||||.||... ..|||. ---YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGC K-------GVKEIKEHAFF . |..|||.| .| GGNDFGDKGAEEIKNHPWF |
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Kinase | 9978.AA | NDR | 1493-1805 | 35 | 1.2e-124 | 386.55 | In-house | 1-350 (350) | Show / Hide |
Range on Protein: 1493-1805 Range on HMM: 1-350/350 Sequence Identity: 35% (126 aa) FEFIKMLGKGAYGGVYLVKKKNTNDLFAMKVIDCSGKLDKKYLETLQSEKNVFEVIT--GDWVVKAFYSFVHENYLCFVLEYMMGGDFNK---ILSLYTA ||.|| .||||.| |.||.||.|....|||.. | ...| . ...|. .. . .||||..||| ...||..| ||. |||.. .|. . FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI LDQWIVEIYIAELVLAIEYLHSMDIVHRDLKPDNMLIDTTGHLKLADFGLSEVGFK-----------------TKLNKHINKTDEDPSQQGAGELVGINI .. . ||||.|.|||..|.| ..|||.|||| ||| ||.|| ||||. |. | . . .| . ... . |. FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYST-FHWTHNSWYYQNMKEHRPQDFMDNW DEANKENEF----KIEIQV---EGMINNEKEQQKR------IVGTPDYIAPEIITGESTNNKSLDWWSMGVIMYEFLVGLPPFNADSVEEIFDNIKNLRM ....... ... |. ..||....|.| .||||||.|||..... .|.. |||| |.||||.||| |||..|...|....|.| . NSNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQ EWPEI-GDINDGDKISPEAYDLIKRLLNPNYKERLGA--KGVKEIKEHAFF |... .. ..|||| |||.||..|. ..|||. ||| ||| | || TWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF |
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Kinase | 9978.AA | S_TKc | 1493-1805 | 25 | 2.4e-86 | 294.08 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 1493-1805 Range on HMM: 1-231/231 Sequence Identity: 25% (83 aa) FEFIKMLGKGAYGGVYLVKKKNTNDLFAMKVIDCSGKLDKKYLETLQSEKNVFEVITGDWVVKAFYSFVHENYLCFVLEYMMG--GDFNKILSLYTA--- .|... .||||.| ||....|.|. ..|.|.|. |....| .. . ...|| ...|.. ..|..|.||. | || ... . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---LDQWIVEIYIAELVLAIEYLHSMDIVHRDLKPDNMLIDTTGHLKLADFGLSEVGFKTKLNKHINKTDEDPSQQGAGELVGINIDEANKENEFKIEIQ .. . |......|.||.||. |.||||||.| |.|. |.|..||||. . RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------------------------------- VEGMINNEKEQQKRIVGTPDYIAPEIITGESTNNK-SLDWWSMGVIMYEFLVGLPPFNADSVEEIFDNIKNLRMEWPEIGDINDGDKISPEAYDLIKRLL . ..|||.|.|||.. .| . |||| |.|.||.|.| ||| ....|..|. |||| |.|...| ------------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------------SPEAKDFIRKCL NPNYKERLGAKGVKE----IKEHAFF . . ..|..| . . || | .| QKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 9978.AA | AktR | 1493-1805 | 31 | 6.3e-79 | 268.53 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 1493-1805 Range on HMM: 1-268/268 Sequence Identity: 31% (101 aa) FEFIKMLGKGAYGGVYLVKKK-NTNDLFAMKVIDCSGKLDKKYLETLQSEKNVFE-VITGDWVVKAFYSFVHENYLCFVLEYMMGGDFNKILSLYTALDQ |...|.|||||.| ||||.|| ......|||.|. . ... . .. |.|. | . || .|.| ...| |..||. ||. .|. .. FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE WIVEIYIAELVLAIEYLHSM-DIVHRDLKPDNMLIDTTGHLKLADFGLSEVGFKTKLNKHINKTDEDPSQQGAGELVGINIDEANKENEFKIEIQVEGMI . .|.|. .||.||||. .|. |||||.| |.| ||.|..|||||. ..|. EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK---------------------------------------------LQFMM -NNEKEQQKRIVGTPDYIAPEIITGESTNNKSLDWWSMGVIMYEFLVGLPPFNADSVEEIFDNIKNLR-MEWPEIGDINDGDKISPEAYDLIK-RLLNPN ..|| .. ..||| |.|||.|| . ||| |||. |. || ..|.|||.... ...|..||. . . ... ..|... |||. .||. | HYDEK--AYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNK------FPYPSYFSSQCKDLIQRKLLCKN YKERLG--AKGVKEIKEHAFF ..||| ..| .|||.| .| PNKRLGYYCNGWEEIKSHPWF |
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Kinase | 9978.AA | RSK | 1496-1805 | 27 | 1.2e-71 | 244.37 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 1496-1805 Range on HMM: 1-278/278 Sequence Identity: 27% (92 aa) IKMLGKGAYGGVYLVKKK---NTNDLFAMKVIDCSGKLDKKY-LETLQSEKNVFEVIT-GDWVVKAFYSFVHENYLCFVLEYMMGGD-FNKILSLYTA-- .|.||.|.|| |.|..|. .|. ..||||.. . .. ... | |. | .. .|. .|.| | .| ..||..||. | ... . LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC LDQWIVEIYIAELVLAIEYLHSMDIVHRDLKPDNMLIDT---TGHLKLADFGLSEVGFKTKLNKHINKTDEDPSQQGAGELVGINIDEANKENEFKIEIQ .. . .|.||.|||.|.||. .|.||||||.|.| | ||.|| |||.. . FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF------------------------------------------- VEGMINNEKEQQKRIVGTPDYIAPEIIT---GESTNNKSLDWWSMGVIMYEFLVGLPPFNA---DSVEEIFDNIKNLR--MEWPEIGDINDGDKISPEAY ...... . ..| .|.|||... .... .|. |||| ||.||| |.| ||| . .. .||...|.. . .. |. ...|.|| ----RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNW------QYLSQEAK DLIKRLLNPNYKERLG--AKGVKEIKEHAFF |||...| . . ||| ....|||.|..| DLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | 9978.AA | DMPK | 1493-1636 | 42 | 4.2e-57 | 139.18 | In-house | 1-145 (270) | Show / Hide |
Range on Protein: 1493-1636 Range on HMM: 1-145/270 Sequence Identity: 42% (61 aa) FEFIKMLGKGAYGGVYLVKKKNTNDLFAMKVIDCSGKLDKKYLETLQSEKNVFEVITGDWVVKAFYSFVHENYLCFVLEYMMGGDFNKILSLYT-ALDQW ||..| |.|. | | .|. |.||| .|||.. | . |... . |... .| | |||| .| ||| ||| .| | .. FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED IVEIYIAELVLAIEYLHSMDIVHRDLKPDNMLIDTTGHLKLADFG |.||.|||| .|.| |||| ||||||.| .||.|||||| MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFG |
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Kinase | 9978.AA | Akt | 1493-1638 | 40 | 1.3e-51 | 163.24 | In-house | 233-380 (264) | Show / Hide |
Range on Protein: 1493-1638 Range on HMM: 233-380/264 Sequence Identity: 40% (60 aa) FEFIKMLGKGAYGGVYLVKKKNTNDLF-AMKVIDCSGKLDKKYLETLQSEKNVFEVITGDWVVKAFYSFVHENYLCFVLEYMMGGDFNKILSLYTALDQW |.|.|.||||..| |.|||||.|.... ||||. . ..|...| . |.|. . . .|. ||| ...|.||..|. ||. |. . FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED IVEIYIAELVLAIEYLHSMDIVHRD-LKPDNMLIDTTGHLKLADFGLS |.||..||||.|||..|. || ||| | |.| .||..|.||||. RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLC |
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Kinase | 9978.AA | SGK | 1493-1638 | 32 | 9.1e-45 | 135.89 | In-house | 1-172 (283) | Show / Hide |
Range on Protein: 1493-1638 Range on HMM: 1-172/283 Sequence Identity: 32% (56 aa) FEFIKMLGKGAYGGVYLVKKKNT------------------NDLFAMKVIDCSGKL-------DKKYLETLQSEK-NVFEVITGDWVVKAFYSFVHENYL |.|.| .||| .| ||.||.| . ...||||. . || ..|. .. . |. |.| . .| FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL CFVLEYMMGGDFNKILSLYTALDQWIVEIYIAELVLAIEYLHSMDIVHRDLKPDNMLIDTTGHLKLADFGLS ||..|. ||. | . . .| ||.|.|.||||| ||..|||||.| | | ||..| ||||. YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLC |
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Kinase | 9978.AA | RSK-Unclassified | 1493-1638 | 35 | 3.8e-44 | 136.26 | In-house | 1-148 (283) | Show / Hide |
Range on Protein: 1493-1638 Range on HMM: 1-148/283 Sequence Identity: 35% (53 aa) FEFIKMLGKGAYGGVYLVKKKNTNDLFAMKVIDCSGKLDKKYLETLQSEKNVFEVITGDWVVKAFYSFVHENYLCFVLEYMMGGDFNKILS--LYTALDQ |. ....|.| | ||||.||.|. ..|||| . . .. |.|. . .|. ..|| . || ..|| ||||| . | . FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE WIVEIYIAELVLAIEYLHSMDIVHRDLKPDNMLIDTTGHLKLADFGLS | .|..| ..| |||| |.. ||||||| . . || .| ||.|| DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLS |
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Kinase | 9978.AA | DMPK | 1700-1805 | 40 | 1.7e-40 | 97.21 | In-house | 162-270 (270) | Show / Hide |
Range on Protein: 1700-1805 Range on HMM: 162-270/270 Sequence Identity: 40% (46 aa) VGTPDYIAPEIITGESTN-----NKSLDWWSMGVIMYEFLVGLPPFNADSVEEIFDNIKNL---RMEWPEIGDINDGDKISPEAYDLIKRLLNPNYKERL |||||||.||. . ... .. ||||.||.||| |.| || |||. | . .| | ... |. ..|.|| |||..|| . .||| VGTPDYISPEVLQAMEDDGKGRYGPECDWWSVGVCMYEMLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPK----WDVSEEAKDLICQLLC-DREERL GAKGVKEIKEHAFF | |. ..|.| || GRNGYEDFKCHPFF |
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Kinase | 9978.AA | Pkinase | 1493-1640 | 28 | 2.7e-40 | 143.58 | Pfam | 1-161 (293) | Show / Hide |
Range on Protein: 1493-1640 Range on HMM: 1-161/293 Sequence Identity: 28% (46 aa) FEFIKMLGKGAYGGVYLVKKKNTNDLFAMKVIDCSGKLDKKYLETLQS--EKNVFEVITGDWVVKAFYSFVHENYLCFVLEYMMGG----DFNKILS--L ..... .|.|..| ||. ..|.|....|.|.|. . . ... ..|. | . . . .|. ...| ......|.||..|| | ..| YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR YTAL--DQWIVEIYIAELVLAIEYLHSMDIVHRDLKPDNMLIDTTGHL----KLADFGLSEV .... . | . |. ... ..||.||| |.||||||.| ||| .||. |..||||... HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQ |
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Kinase | 9978.AA | SGK | 1701-1805 | 38 | 3.5e-36 | 108.89 | In-house | 187-283 (283) | Show / Hide |
Range on Protein: 1701-1805 Range on HMM: 187-283/283 Sequence Identity: 38% (41 aa) GTPDYIAPEIITGESTNNKSLDWWSMGVIMYEFLVGLPPFNADSVEEIFDNIKNLRMEWPEIGDINDGDKISPEAYDLIKRLLNPNYKERLGAK-GVKEI ||| | |||.. .. . .. |||..| ..||...||||| ... .||| | . | .|..| |||. ||. . |.|||.| . || GTPEYLAPEVLRKQ-PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPP--------QMSNDAWDLIQGLLQKDPKKRLGTKRDFMEI KEHAFF |.| || KNHPFF |
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Kinase | 9978.AA | Akt | 1701-1805 | 42 | 8.1e-34 | 105.43 | In-house | 164-264 (264) | Show / Hide |
Range on Protein: 1701-1805 Range on HMM: 164-264/264 Sequence Identity: 42% (46 aa) GTPDYIAPEIITGESTNNKSLDWWS-MGVIMYEFLVGLPPFNADSVEEIFDNIKNLRMEWPEIGDINDGDKISPEAYDLIKRLLNPNYKERLG--AKGVK ||| |.||||. | |. |||. |..|||.. |.||| .. ... |..||| . |. . |.||||. |||..||| ..|.||| .... GTPEYLAPEILNG-NGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPD----K--DWISPECKDLISGLLNKDPKKRLGGGPNDAQ EIKEHAFF |||.| .| EIKRHPWF |
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Kinase | 9978.AA | RSK-Unclassified | 1700-1805 | 39 | 7.5e-32 | 96.93 | In-house | 183-283 (283) | Show / Hide |
Range on Protein: 1700-1805 Range on HMM: 183-283/283 Sequence Identity: 39% (43 aa) VGTPDYIAPEIITGESTNNKSLDWWSMGVIMYEFLVGLPPFNADSVEEIFDNIKNLRMEWPEIGDINDGDKISPEAYDLIKRLLNPNYKERLGAK-G-VK .|| .|.|||.| . | ||| .|..||| |.|.||. .. .|.| || . |. || .. ||||.||. | |||.| | CGTEEYLAPEMIRR-CGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPH------DSYISNNCRDLIKKLLQRNPAKRLGCKMGDAD EIKEHAFF .|| | || DIKRHPFF |
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Kinase | 9978.AA | Pkinase | 1699-1805 | 26 | 1.7e-22 | 80.6 | Pfam | 171-293 (293) | Show / Hide |
Range on Protein: 1699-1805 Range on HMM: 171-293/293 Sequence Identity: 26% (33 aa) IVGTPDYIAPEIITGESTNNKSLDWWSMGVIMYEFLVGLPPFNAD------SVEEIFDNIKNLRMEWPEIGDINDG-------------DKISPEAYDLI ..|||.|.|||.| | . .. |.||.|.|.||.| | ||| . . .....|. . .... ... ...|.|. |.| FCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFI KRLLNPNYKERLGAKGVKEIKEHAFF |..|... |.|.. ..|..| .| KWCLCKDPKKRPT---AEQILQHPWF |
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Kinase | 9978.AA | TyrKc | 1493-1805 | 20 | 2.5e-10 | -55.65 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 1493-1805 Range on HMM: 1-280/280 Sequence Identity: 20% (70 aa) FEFIKMLGKGAYGGVYLVKKKNTNDLFAMKVIDCSGKLDKKYLETLQSEKNVFEVI--TGDWVVKAFYSFVHE-------NYLCFVLEYMMGGDFNKILS ...|.|| ||.| ||. . | | |.. . .| . .| .. . . .|. . ... |. |.||| .|| .. | ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR LYTALDQWIVEIYIAELVL-------AIEYLHSMDIVHRDLKPDNMLIDTTGHLKLADFGLSEVGFKT-KLNKHINKTDEDPSQQGAGELVGINIDEANK . . ..|. |||||. ..|||| | |.. .. | .||||| . . KHRPK------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG---------------------------- ENEFKIEIQVEGMINNEKEQQKRI---VGTPD-----YIAPEIITGESTNNKSLDWWSMGVIMYEFL-VGLPPFNA-----DSVEEIFDNIKNL-RMEWP | .. .| |. . ||| | . || | || || |.| . | .| | .|.. ..|. ||. | ----------------ESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS-DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQP EIGDINDGDKI-----SPEAYDLIKRLLNPNYKERLGAKGVKEIKEHAFF . . . ..| |...|. . . ..| . . | .| PNDY----P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-----HECF |
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Kinase | 9978.AA | Pkinase_Tyr | 1605-1638 | 44 | 7e-06 | 20.63 | Pfam | 125-158 (270) | Show / Hide |
Range on Protein: 1605-1638 Range on HMM: 125-158/270 Sequence Identity: 44% (15 aa) EYLHSMDIVHRDLKPDNMLIDTTGHLKLADFGLS |||.|. ..|||| | |.. ... | .||||. EYLESKNCIHRDLAARNCLVTENNVVKICDFGLA |
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Kinase | 9978.AA | Pkinase_Tyr | 1493-1509 | 52 | 0.10141 | 6.45 | Pfam | 1-17 (270) | Show / Hide |
Range on Protein: 1493-1509 Range on HMM: 1-17/270 Sequence Identity: 52% (9 aa) FEFIKMLGKGAYGGVYL .|.|.||.||.| ||. ITFGKKLGEGAFGEVYK |