Gene 8040 (Tetrahymena)

8040

Species: Tetrahymena
Alias: 8040, TTHERM_00500960, 3716.m00071, 63.m00218, 396, PreTt08040
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: AGC
Family: AktR

Sequence

Name Sequence Type Origin Length Description Download
8040.AA Protein None 414 None Fasta, JSON
8040.kin_dom Protein Kinase Domain None 260 None Fasta, JSON
8040.NA RNA None 1245 None Fasta, JSON

Protein domain

Protein domains of 8040.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 8040.AA AGC 91-350 29 1.8e-165 431.84 In-house 1-395 (395) Show / Hide 
Range on Protein: 91-350
Range on HMM: 1-395/395
Sequence Identity: 29% (119 aa)

FDRLQNLGSGAYGDVILVKKK------TNNKQFAMKIIKKSK-IVSRN--LNPQMIIE------------KNVLLENK----------HPFLVR-LKYSF
|. |  .| |..| |.||.||      ...|..|||..||.. || ..     . ..|            .|.| . .          |||.|. |.|||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTEKK--LYLVMEYCP---------GG-ELYTYLV---NNKKFSIEVSRFIAAE-------VLLGLEYLHKSMKIIYRD-LKPENILISEDGHLKIADFG
|....  ||.||||.|         || ||...|    ....|. |..||.|||       ..|.|||||. |.||.|| |||||||. ||||.|..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAKQFKRED--------------------------------------------------ELTTTLRG--TPEYIAPEVILAEQTGKGYGLQCDIWA--FG
|.|......                                                  ..|.|. |  ||||.|||..        || .||.|.  .|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL--------YGKACDWWSFGLG

IFLFEIISGNPPFTDKNRN--------WAGIKQKIL------QNKPQFT----------ADFTEESQDLICKCLKDNPLERPN----------WDEIKVH
....| ..| |||...|..         . . |||.      ..|..|             |..| .||| |.|. .| .|.            .||| |
CLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNH

PFF
|.|
PWF
Kinase 8040.AA AktR 91-350 51 8.4e-160 537.18 In-house 1-268 (268) Show / Hide 
Range on Protein: 91-350
Range on HMM: 1-268/268
Sequence Identity: 51% (139 aa)

FDRLQNLGSGAYGDVILVKKK-TNNKQFAMKIIKKSKIVSRNLNPQMIIEKNVLL-ENKHPFLVRLKYSFQTEKKLYLVMEYCPGGELYTYLVNNKKFSI
|.....||.||.|.|.||.|| .|.||.|||.|||.||. ||.. ..| |.|..  ...|||.|.|.|.|||..||...|||||||||...| ..|||| 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

EVSRFIAAEVLLGLEYLHKSMKIIYRDLKPENILISEDGHLKIADFGLAK-QFKR-EDELTTTLRGTPEYIAPEVILAEQTGKGYGLQCDIWAFGIFLFE
|..||..|..||.|||||. |.||||||||||||. ||||.||.||||.| ||.. .||..... |||||.|||.|. .   ||.. ..|.||||||..|
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKK---KGHNKSVDWWAFGIFIYE

IISGNPPFTDKNRNWAGIKQKILQ-NKPQFTADFTEESQDLIC-KCLKDNPLERP-----NWDEIKVHPFF
...|.|||..||.|.  .|.|| | ||......|... .|||. |.|..|| .|.     .|.||| ||.|
MVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 8040.AA Ciliate-E2b 91-350 35 1e-122 374.64 In-house 1-272 (272) Show / Hide 
Range on Protein: 91-350
Range on HMM: 1-272/272
Sequence Identity: 35% (97 aa)

FDRLQNLGSGAYGDVILVKK-KTNNKQFAMKIIKKSKIVSRNLNPQMIIEKNVLLENKHPFLVRLKYSFQTEKKLYLVMEYCPGGELYTYLVNNK--KFS
..    ||.|..| | ||.. |. ....||| |.|..|. .|.  .|..|||||. ..|||......||......|..||.| |.|| ... . .   .|
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLS

IEVSRFIAAEVLLGLEYLHKSMKIIYRDLKPENILISEDGHLKIADFGLAKQFKREDE---LTTTLRGTPEYIAPEVIL-AEQTGKGYGLQCDIWAFGIF
 ..|.|. |...|.||||| . .|||||.|||||.. ..|..|..|.|.|| .. . |    |.|..|||.| |||.|   .  ||||. . |||..||.
TYDSQFYIASICLCLEYLH-NQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGIC

LFEIISGNPPFTDKNRNWAGIKQKILQN--KPQFTADFTEESQ--DLICKCLKDNPLERP--NWDEIKVHPFF
|.|...| .|.. . ..   | |.|...  . || . .....   .|. .||. .|  |.   ..  | ||.|
LYEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQFPSYCKDKMADKKLMLQCLQKMPEVRLGGSYSWLKSHPWF
Kinase 8040.AA Akt 91-350 41 4.6e-105 336.79 In-house 1-264 (264) Show / Hide 
Range on Protein: 91-350
Range on HMM: 1-264/264
Sequence Identity: 41% (113 aa)

FDRLQNLGSGAYGDVILVKKKTNNKQF-AMKIIKKSKIVSRNLNPQMIIEKNVLLENKHPFLVRLKYSFQTEKKLYLVMEYCPGGELYTYLVNNKKFSIE
|| |  ||.|..| |.||||| ..| . |||..||..|. .|   . . |.|.|   .|||.| |.|||||..|||.||.||.||||...|   ..|| .
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

VSRFIAAEVLLGLEYLHKSMKIIYRD-LKPENILISEDGHLKIADFGLAKQF-KREDELTTTLRGTPEYIAPEVILAEQTGKGYGLQCDIWA-FGIFLFE
  || .||. |..|.||. . ||||| |||||||...|||....||||.|.  . ... |.|. |||||.|||...    |.|.. ..|.|. .|....|
RARFYCAEIILAIEHLHS-KNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILN----GNGHTKAVDWWGSLGCVMYE

IISGNPPFTDKNRNWAGIKQKILQNKPQFT--ADFTEESQDLICKCLKDNPLERP----N-WDEIKVHPFF
 . |.||| ....      .||.... .|     .  | .||| ..|. .| .|.    |  .||| ||.|
MMCGRPPFYNQDH--HQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 8040.AA S_TKc 91-350 35 1.4e-102 348.03 SMART 1-231 (231) Show / Hide 
Range on Protein: 91-350
Range on HMM: 1-231/231
Sequence Identity: 35% (97 aa)

FDRLQNLGSGAYGDVILVKKKTNNKQFAMKIIKKSKIVSRNLNPQMIIEKNVLLENKHPFLVRLKYSFQTEKKLYLVMEYCPG--GELYTYLVNNKK---
.. |. .|.||.| | ....|  ....|.||||           ... | ..| . .||..|.|...||. ..||.|||||.|  |.|..|......   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSIEVSRFIAAEVLLGLEYLHKSMKIIYRDLKPENILISEDGHLKIADFGLAKQFKREDELTTTLRGTPEYIAPEVILAEQTGKGYGL-QCDIWAFG
   |.  . ||........|||.|.  .||.|||||||||..|  |.||.|||||.|.       ||. |||.|.||||.       |||   ||.|..|
RFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL-------GYGKCKCDWWSCG

IFLFEIISGNPPFTDKNRNWAGIKQKILQNKPQFTADFTEESQDLICKCLKDNPLERPNWDEIKV-------HPFF
. |.| ..| |||     . . . .||.          ..|  |.|.|||. .| .||   |.         ||.|
CILYEMLCGYPPFP----QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 8040.AA RSK 94-350 40 2.2e-99 336.5 In-house 1-278 (278) Show / Hide 
Range on Protein: 94-350
Range on HMM: 1-278/278
Sequence Identity: 40% (113 aa)

LQNLGSGAYGDVILVKKK---TNNKQFAMKIIKKSKIVSRNLNPQMII-EKNVLLENK-HPFLVRLKYSFQTEKKLYLVMEYCPGGELYTYLVNNKK---
|. || |.|| | |..|.    .....|||..||.||| |.        | |.|.. . |||.|.|.|.||||.||||.||||.||||.| | . |    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSIEVSRFIAAEVLLGLEYLHKSMKIIYRDLKPENILISE---DGHLKIADFGLAKQFKRE-DELTTTLRGTPEYIAPEVIL-AEQTGKGYGLQCDIWAF
|| .  .|..||. | .|.||.   ||.|||||||||  .   .||.|. |||..|||. .  ..| | ..| ||.|||..  |.  ..|.. .||.| .
FSEDEACFYMAEIVLAVEHLHQQG-IIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN-QQGGHDKACDWWSL

GIFLFEIISGNPPFTDKNR-NWAGIKQKILQNK--PQFT--ADFTEESQDLICKCLKDNPLERPN-----WDEIKVHPFF
|. ..|  .|.|||.  |. | . | ..|...|  . .   .  ..| .||| |.|. .|  |..      .||| ||.|
GVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 8040.AA SGK 91-350 37 4.9e-96 297.06 In-house 1-283 (283) Show / Hide 
Range on Protein: 91-350
Range on HMM: 1-283/283
Sequence Identity: 37% (108 aa)

FDRLQNLGSGAYGDVILVKKKTN------------------NKQFAMKIIKKSKIV-------SRNLNPQMIIEKNVLLEN-KHPFLVRLKYSFQTEKKL
|| |. .| | .| | .||.|                     | .|||...|  |.        ...     .|.||.| | ||||.| |.|.|||..||
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLVMEYCPGGELYTYLVNNKKFSIEVSRFIAAEVLLGLEYLHKSMKIIYRDLKPENILISEDGHLKIADFGLAKQFKREDELTTTLRGTPEYIAPEVILA
|.||.|  |||.  .|   |.|.  ..|| |||. . |||||.. .||||||||||||   .||... ||||.|.   . . |.|  ||||| ||||.. 
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQ-DIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLR-

EQTGKGYGLQCDIWAFGIFLFEIISGNPPFTDKNRNWAGIKQKILQNKPQFTADFTEESQDLICKCLKDNPLERPNWD----EIKVHPFF
   .....   | |  |..|.| ..| ||| ..|.  .   ..|.  . |.   .. .  |||   |. .| .| .      ||| ||||
---KQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNK--QQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 8040.AA PKA 91-350 43 1.6e-94 320.35 In-house 1-263 (263) Show / Hide 
Range on Protein: 91-350
Range on HMM: 1-263/263
Sequence Identity: 43% (118 aa)

FDRLQNLGSGAYGDVILVKKKTNNKQFAMKIIKKSKIVSRNLNPQMIIEKNVLLENKHPFLVR-LKYSFQTEKKLYLVMEYCPGGELYTYLVNNKKFSIE
|...| ||.| .| | |...|.. . .|||..||..|| ..     . |||.|.. ||||.|. ....||....||.||||.||||. .|| ....||  
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

VSRFIAA-EVLLGLEYLHKSMKIIYRDLKPENILISEDGHLKIADFGLAKQFKREDELTTTLRGTPEYIAPEVILAEQTGK-GYGLQCDIWAFGIFLFEI
...|.|| .. | ||||| |. ||||||||||||| ..||.||.||| ||  .     | || |||||.|||.|.    .| |.|   | ||.||  .| 
HAKFYAASQIVLALEYLH-SQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD---RTWTLCGTPEYLAPEIIQ----SKNGHGKSVDWWALGILIYEM

ISGNPPFTDKNRNWAGIKQKILQNKPQFTADFTEES---QDLICKCLKDNPLERP-NWDE----IKVHPFF
 .| |||.|.||. ..| .||.. | .|   |.       ||| | |  .. .|  | ..    || |..|
LAGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 8040.AA Ciliate-E2 91-350 27 7.5e-94 318.09 In-house 1-365 (365) Show / Hide 
Range on Protein: 91-350
Range on HMM: 1-365/365
Sequence Identity: 27% (103 aa)

FDRLQNLGSGAYG-----DVILVKK------------------KTNNKQFAMKIIKKSKIVSRNLNPQMI----------IEKNVLLENKHPFLVRLKYS
.. .. .|.|..|      |..|.|                  |...|..||||.||..| . .   ...          .|||.| ...||........
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--TEKKLYLVMEYCPGGELYTYLVNN-----------KKFSIEVSR---------------FIAAEVLLGLEYLHKSMKIIYRDLKPENILISEDGHL
||  .....||||||| ||.|. |. ||           |.|...  .               |..|...|.|||||.  .||.||.||||||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIADFGLAKQFKRE-------------------------------DELTTTLRGTPEYIAPEVILAEQ-----TGKGYGLQCDIWAFGIFLFEIISGNPP
||.||||.|... .                               .... |. |||.| |||..  ..     ..|||. .||||..|. |.| ..|.||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FTDKNRNWAGIKQKILQNKPQFT------------------ADFTEESQDLICK----CLKDNPLERPN-WDEIKVHPFF
|           |.|.|.| .|                    . ..| .||| |    .|. .| .|.. |..|. ||.|
F----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 8040.AA Pkinase 91-350 34 2.3e-92 317.97 Pfam 1-293 (293) Show / Hide 
Range on Protein: 91-350
Range on HMM: 1-293/293
Sequence Identity: 34% (106 aa)

FDRLQNLGSGAYGDVILVKKKTNNKQFAMKIIKKSKIVSRN------LNPQMIIEKNVLLENKHPFLVRLKYSFQTEKKLYLVMEYCPGG----ELYTYL
. ... .|||..| | . ..| ..|..|.|||||... |        |      |  .... .||. |||...|......|.|||||.||    .|..|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-----SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

V--NNKKF--SIEVSRFIAAEVLLGLEYLHKSMKIIYRDLKPENILISEDGHL----KIADFGLAKQF-KREDELTTTLRGTPEYIAPEVILAEQTGKGY
   ....|  | .. .|.. ..| ||||.|. |.||.||||||||||...||.    ||.||||||||    .. .||. |||.|.|||||.   .|..|
STWRHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR---GGQYY

GLQCDIWAFGIFLFEIISGNPPFTDK--NRNWAGIKQKILQNKP-QFTADFT-----------------------EESQDLICKCLKDNPLERPNWDEIK
|  .|.|..|. |.| ..|.||| ..    | .  .|.| .... ..  |.                        || .|.|..||. .| .||....|.
GPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL

VHPFF
 ||.|
QHPWF
Kinase 8040.AA Ciliate-E2-Unclassified 91-350 28 1e-86 294.4 In-house 1-352 (352) Show / Hide 
Range on Protein: 91-350
Range on HMM: 1-352/352
Sequence Identity: 28% (101 aa)

FDRLQNLGSGAYGDVILVKKKTNNKQFAMKIIKKSKIVS----RNLNPQMIIEKNVLLENK-------------------HPFLVRLKYSFQTEKKLYLV
.  .. .|.|..|.| ....| .....|||..||..|..    .| . ... |.. . ..|                   |||.|.. | ||.....|.|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYCPGGELYTYLVNNKK-----------------FSIEVSR-----FIAAEVLLGLEYLHKSMKIIYRDLKPENILISEDG---HLKIADFGLAK----
||||.||.|  |. ..||                 |. . ..     |..|..|.||||||.. .||.||.||||||....|   ..||.|||..|    
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

----QFKRE--------DELTTTLRGTPEYI----APEVILAEQTGKGYGLQ----CDIWAFGIFLFEIISGNPPFTDKNRNW--------------AGI
    . ..         .....|  |||.|.    ||||.     |..|. .    ||||..|. |.|.. |..|| |.|..                 .
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVL----QGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQL

KQKILQNKPQFTA--------DFTEESQDLIC----KCLKDNPLERPNWDEIKVHPFF
.|.|.|...||          .  .| .|.|     |.|| || .|.....|. ||.|
YQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 8040.AA p70 91-350 34 4.8e-83 282.19 In-house 1-299 (299) Show / Hide 
Range on Protein: 91-350
Range on HMM: 1-299/299
Sequence Identity: 34% (105 aa)

FDRLQNLGSGAYGDVILVKKKT---NNKQFAMKIIKKSKIVSRNLNPQMII--------------------------EKNVLLENKHPFLVRLKYSFQTE
| .|  || |.|| | .|.| |   ..| .||| ..| |||      .                             | |.| | ||||.. | |.|||.
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

KKLYLVMEYCPGGELYTYLVNNKKFSIEVSRFIAAEVLLGLEYLHKSMKIIYRDLKPENILISEDGHLKIADFGLAKQFKREDEL----------TTTLR
 ||||. || .||||.. |     .  .. .| ..|. . ||.||.   ||||||||||.. .. ||..  |||| |.   ...           | |. 
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQ-HGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFC

GTPEYIAPEVILAEQTGKGYGLQCDIWAFGIFLFEIISGNPPFTDKNRNWAGIKQKILQNK--PQFTADFTEESQDLICKCLKDNPLERPN-----WDEI
||.|| |||...    ..|..  .| |. |. ..    | ||||  ||  . .  |||..|  ..  .  |.|  ||| | || .| .| .       .|
GTIEYMAPEILM----RCGHNHAVDWWSLGCLMYDMLTGGPPFTGENR--KKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADI

KVHPFF
..||||
QEHPFF
Kinase 8040.AA TyrKc 91-350 23 2e-18 68.47 SMART 1-280 (280) Show / Hide 
Range on Protein: 91-350
Range on HMM: 1-280/280
Sequence Identity: 23% (71 aa)

FDRLQNLGSGAYGDVILVKKKTNNKQFAMKIIKKSKIVSRNLNPQMIIEKNVLLEN--KHPFLVRLKYSFQTE-------KKLYLVMEYCPGGELYTYLV
   .. ||.||.| | . . |    | | | .|...         .. | ... .   .|| .|||     ..       . |..||||.|.| |  || 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NNKK-FSIEVSRFIAAEVLLGLEYLHKSMKIIYRDLKPENILISEDGHLKIADFGLAKQFKRE-------DELTT----TLR--GTPEYIAPEVILAEQT
.... .. .    ..  .  | |||| |...| |||   |.|..|... ||.||||..  . .       |  ..      .        |||.|   ..
KHRPKLCMKDLLSFCWQIACGMEYLH-SKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NY

GKGYGLQCDIWAFGIFLFEIIS-GNPPFTD---KNRNWAGIKQKILQN-KPQFTAD--------FTEESQDLICKCLKDNPLERPNWDEIKVHPFF
|| .  . |.|.||. ..|| . | .|  .   .  ... . ... |   .   ..         ..|  ... .| . .| .||.  ||  | .|
GK-FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 8040.AA Pkinase_Tyr 147-294 29 2.9e-17 59.07 Pfam 62-216 (270) Show / Hide 
Range on Protein: 147-294
Range on HMM: 62-216/270
Sequence Identity: 29% (47 aa)

KHPFLVRLKYSFQ-TEKK--LYLVMEYCPGGELYTYLVN----NKKFSIEVSRFIAAEVLLGLEYLHKSMKIIYRDLKPENILISEDGHLKIADFGLAKQ
.|| .|||       ..   .|.||||.|.| |..|| .    .......    .....  |.|||. |...| |||   |.|..|... ||.|||||. 
HHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLE-SKNCIHRDLAARNCLVTENNVVKICDFGLARD

FKREDEL-TTTL--RGTPEYIAPEVILAEQTGKGYGLQCDIWAFGIFLFEIIS-GNPP-F
   .|.  ...   .      |||.|        .  . |.|.||. ..||.. |  | .
IYNDDYYYRKRGGGKLPIKWMAPECINYGK----FTTKSDVWSFGVLMWEIFTYGEQPTY
Kinase 8040.AA Pkinase_Tyr 91-105 40 5.522701 0.57 Pfam 1-15 (270) Show / Hide 
Range on Protein: 91-105
Range on HMM: 1-15/270
Sequence Identity: 40% (6 aa)

FDRLQNLGSGAYGDV
   .. ||.||.|.|
ITFGKKLGEGAFGEV