Gene 26470 (Tetrahymena)

26470

Species: Tetrahymena
Alias: PreTt26470, 3831.m01572, 108, 26470, 48.m00233, TTHERM_00431290
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
26470.NA RNA None 1077 None Fasta, JSON
26470.AA Protein None 358 None Fasta, JSON
26470.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of 26470.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 26470.AA AGC 30-286 34 2.6e-193 505.47 In-house 1-395 (395) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-395/395
Sequence Identity: 34% (138 aa)

FTLLKMIGEGAYAKVYLVRKL------DNQKVYALKILKKKK-IQELG--QQHRVILE------------KDILANIES---------HPFIIK-LHYSF
| .||.||.|.. |||||||       |..|.||.|.||||. |...   ...... |            ..||... .         ||||.| |||||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QNDTK--LFFALDFCP---------GG-ELFSILS---RKHKFDEEQCRFYAAQ-------IVLAIEHLHK-HNIIYRD-LKPENVILDKEGYIRISDFG
|....  |.| ....|         || |||..|    .. .||||..|||||.       ||||.|.||. ..||.|| |||||. ||..|.|...|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKDNIED---------------------------------------------------QTAFSVCG--TPEYLAPEILNNSGHGKPVDWWA--LGNLIY
|.| .. |                                                   ... . ||  ||||.|||||    .||..|||.  || |.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLTGLPPFYVEN---------NREELFKKIK------YTEITIP----------SYFSKACKDLLTRLFLKNPYQRLGSN-------GAEEIKDHPWF
|||||.|||| .|         |..|.|.||.        ....|          ..||. .|||...|. |.| .|||..       ||||||.||||
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 26470.AA AktR 30-286 55 4.1e-170 571.45 In-house 1-268 (268) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-268/268
Sequence Identity: 55% (149 aa)

FTLLKMIGEGAYAKVYLVRKL-DNQKVYALKILKKKKIQELGQQHRVILEKDILANIESHPFIIKLHYSFQNDTKLFFALDFCPGGELFSILSRKHKFDE
|...|..|.||..|||||.|. ||||.||.|..|||||.|. |.|..|.|..|.... .||||.||||.||...||||....|||||||..|..|.||.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

EQCRFYAAQIVLAIEHLHKH-NIIYRDLKPENVILDKEGYIRISDFGLSK---DNIEDQTAFSVCGTPEYLAPEILNN-SGHGKPVDWWALGNLIYEMLT
|| |||.|||.||.|.||.| |||||||||||  ||..|...|.||||||   .. .|..| |.||||||.|||....  ||.|.|||||.| .||||.|
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GLPPFYVENNREELFKKIKYT--EITIPSYFSKACKDLLT-RLFLKNPYQRLG--SNGAEEIKDHPWF
|.||||..|......|.....  ....|||||..||||.. .|. |||..|||  .||.||||.||||
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 26470.AA Akt 30-286 52 1.2e-164 530.27 In-house 1-264 (264) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-264/264
Sequence Identity: 52% (140 aa)

FTLLKMIGEGAYAKVYLVRKLDNQKVY-ALKILKKKKIQELGQQHRVILEKDILANIESHPFIIKLHYSFQNDTKLFFALDFCPGGELFSILSRKHKFDE
|..||..| |...||.||.| |.||.| |.|.|||..|.. .|   .. |. || ..  ||||..||||||. .||.| .|.|.|||||. |.|| .|.|
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCN-HPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE

EQCRFYAAQIVLAIEHLHKHNIIYRD-LKPENVILDKEGYIRISDFGLSKDN-IED-QTAFSVCGTPEYLAPEILNNSGHGKPVDWWA-LGNLIYEMLTG
.. |||.|.|.|||||||..|||||| |||||. .||.|.|.. ||||.|.| | | ... ..|||||||||||||. ||.|.||||. || ..|||..|
DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG

LPPFYVENNREELFKKIKYTEITIP--SYFSKACKDLLTRLFLKNPYQRLG--SNGAEEIKDHPWF
.||||   .....|||||. .. .|  ...|..||||...|  |.| .|||  .|.|.|||.||||
RPPFYN-QDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 26470.AA SGK 30-286 42 7e-142 441.19 In-house 1-283 (283) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-283/283
Sequence Identity: 42% (121 aa)

FTLLKMIGEGAYAKVYLVRKLDN------------------QKVYALKILKKKKIQ-------ELGQQHRVILEK-DILANIESHPFIIKLHYSFQNDTK
| .|| ||.| . |||.|.. |                   .|.||.|.|.|. |           .|  .  |. .|| |. .||||..|||.||...|
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNM-KHPFIVNLHYAFQTKWK

LFFALDFCPGGELFSILSRKHKFDEEQCRFYAAQIVLAIEHLHKHNIIYRDLKPENVILDKEGYIRISDFGLSKDNIEDQTA-FSVCGTPEYLAPEILNN
|.| .|.  |||.|. | |  .| | . |||||.||.|.|.||. .||||||||||. || .|.... ||||.| .|....  |. ||||||||||.|. 
LYFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRK

SGHGKPVDWWALGNLIYEMLTGLPPFYVENNREELFKKIKYTEITIPSYFSKACKDLLTRLFLKNPYQRLGSN-GAEEIKDHPWF
 .|.. |||| || . |||..||||||  .|..... .|   .. || ..| ...||.. |  |.| .|||.. ...|||.||.|
QPHDRTVDWWCLGCVLYEMMYGLPPFY-SRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 26470.AA PKA 30-286 46 3.5e-119 402.25 In-house 1-263 (263) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-263/263
Sequence Identity: 46% (124 aa)

FTLLKMIGEGAYAKVYLVRKLDNQKVYALKILKKKKIQELGQQHRVILEKDILANIESHPFII-KLHYSFQNDTKLFFALDFCPGGELFSILSRKHKFDE
| ... .| | ...|.|.|. .. . ||.|.||| .|  | |...|. || || || .||||. |. ..||.|..|.. ....||||.|| | .. .|..
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNI-KHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSN

EQCRFYAA-QIVLAIEHLHKHNIIYRDLKPENVILDKEGYIRISDFGLSKDNIEDQTAFSVCGTPEYLAPEILNNS-GHGKPVDWWALGNLIYEMLTGLP
 . .|||| |||||.| ||..|||||||||||  .||.|.| | ||| .| ...|   ...|||||||||||.... ||||.||||||| ||||||.| |
PHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAK-KVDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYP

PFYVEN-NREELFKKIKYTEITIPSYFSKAC---KDLLTRLFLKNPYQRLG--SNGAEEIKDHPWF
||| .| .  ....||   .|  |..|...    |||. .|  ... .|.|  .||.. ||.|.||
PFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 26470.AA RSK 33-286 44 3.3e-118 399.03 In-house 1-278 (278) Show / Hide 
Range on Protein: 33-286
Range on HMM: 1-278/278
Sequence Identity: 44% (123 aa)

LKMIGEGAYAKVYLVRKL---DNQKVYALKILKKKKIQELGQ-QHRVILEKDILANIESHPFIIKLHYSFQNDTKLFFALDFCPGGELFSILSRKHK---
||. |.|.| ||.|.||    |....|| |.|||.||      . ..  | .||. ...||||..|||.|| ..||.  ...|.|||||  |...     
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FDEEQCRFYAAQIVLAIEHLHKHNIIYRDLKPENVILDK---EGYIRISDFGLSKD-NIE-DQTAFSVCGTPEYLAPEILN----NSGHGKPVDWWALGN
|.|. ..||.|.||||.||||.. ||.|||||||...|    || |...|||..|  ...  | . . |.| ||.|||.|.    ..||.| .||| || 
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LIYEMLTGLPPFYV--ENNREELFKKIKYTE--ITIP--SYFSKACKDLLTRLFLKNPYQRLG--SNGAEEIKDHPWF
|.|||||| |||.    |||.|..|.|.  .   |.|  .| |...|||..... ..| .|||   ..|||||.||||
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 26470.AA RSK-Unclassified 30-286 41 1.9e-113 357.8 In-house 1-283 (283) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-283/283
Sequence Identity: 41% (118 aa)

FTLLKMIGEGAYAKVYLVRKLDNQKVYALKILKKKKIQELGQQHRVILEKDILANIESHPFIIKLHYSFQNDTKLFFALDFCPGGELFSILS-RKHK-FD
|   ..|| |   ||||||| | |..||.|.|.|.|.       .|. |..|.| .  ||||..| .|||   .|.  ...|.||..|  |  || | | 
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMA-TTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFC

EEQCRFYAAQIVLAIEHLHKHNIIYRDLKPENVILDKEGYIRISDFGLSKDN---------------------IEDQT-AFSVCGTPEYLAPEILNNSGH
|.. ||||. ...| |.|||  .|||||||.|..|..|| .. .||.||..                      ... . . | ||| ||||||..   ||
EDDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGH

GKPVDWWALGNLIYEMLTGLPPFYVENNREELFKKIKYTEITIP--SYFSKACKDLLTRLFLKNPYQRLGS-NG-AEEIKDHPWF
.| |||| || ..|||| |.||.|  ||..|.|. |   .. .|  || |. |.||. .|  .||  |||.  | |..|| || |
TKAVDWWTLGIVMYEMLFGCPPYYG-NNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase 26470.AA S_TKc 30-286 36 3.5e-106 359.99 SMART 1-231 (231) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-231/231
Sequence Identity: 36% (98 aa)

FTLLKMIGEGAYAKVYLVRKLDNQKVYALKILKKKKIQELGQQHRVILEKDILANIESHPFIIKLHYSFQNDTKLFFALDFCPG--GELFSILSRKHK--
...|. ||.||..|||..|. . ....|.||.|           ... | .|| .   ||.|.||...||. ..|.. ...|.|  |.||... .. .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FDEEQCRFYAAQIVLAIEHLHKHNIIYRDLKPENVILDKEGYIRISDFGLSKDNIEDQTAFSVCGTPEYLAPEILNNSGHGK-PVDWWALGNLIYE
    |.| ..|||..||..|.|..|.|.||.|||||||. ||.   | |.||||..         ..||||.|.|||.|   |.|| ..|||..| ..||
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MLTGLPPFYVENNREELFKKIKYTEITIPSYFSKACKDLLTRLFLKNPYQRLGSNGAEE----IKDHPWF
||.| |||.   . ...||||.          |. .||.. ... |.| .|..   | .    || ||||
MLCGYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 26470.AA RSK 30-286 38 7.50000000001e-103 347.99 In-house 1-271 (271) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-271/271
Sequence Identity: 38% (106 aa)

FTLLKMIGEGAYAKVYLVRKL---DNQKVYALKILKKKKIQELGQQHRVILEKDILANIESHPFIIKLHYSFQNDTKLFFALDFCPGGELFSILSRKHKF
. |...||.|.. |||...|    |... || ||.||...    .  .   | .||...  ||||.||||.||  .|..  .||. ||.||  |...  |
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGH-HPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMF

DEEQCRFYAAQIVLAIEHLHKHNIIYRDLKPENVILDKE----GYIRISDFGLSKDNIEDQT-AFSVCGTPEYLAPEILNNSGHGKPVDWWALGNLIYEM
 |.  .||.| | || |.||.. |..|||||||...| |    | |.| |||..|  . .   . . |.| .|.|||.|.  ||.. .||| .| | |||
SEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEM

LTGLPPFYVENNREELFKKIKYTEITI-------PSYFSKACKDLLTRLFLKNPYQRLGS--NGAEEIKDHPWF
||| .||. ...|.... .|.     .       ... |. .||||....  .| .|||.  ||.|.|| ||||
LTGCTPFQ-NKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase 26470.AA p70 30-286 39 2.6e-102 346.21 In-house 1-299 (299) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-299/299
Sequence Identity: 39% (118 aa)

FTLLKMIGEGAYAKVYLVRKLD---NQKVYALKILKKKKI----QELGQQH----------------------RVILEKDILANIESHPFIIKLHYSFQN
| ||| .|.|.| ||..|||     . |.|| | |.| ||      .                          |   |  ||  .. ||||..|||.|| 
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVK-HPFICDLHYAFQT

DTKLFFALDFCPGGELFSILSRKHKFDEEQCRFYAAQIVLAIEHLHKHNIIYRDLKPENVILDKEGYIRISDFGLSKDNIEDQTA-----------FSVC
. ||.  |.. .|||||  | |.  ..|.  .||.. |..|.||||.| ||||||||||..|.. | .   ||||.|  |.| .            .. |
NGKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFC

GTPEYLAPEILNNSGHGKPVDWWALGNLIYEMLTGLPPFYVENNREELFKKIKYTE--ITIPSYFSKACKDLLTRLFLKNPYQRLG--SNGAEEIKDHPW
||.|| |||||  .||.. ||||.|| |.| |||| |||  | || .  .||      ...| | ..  .||. .|  ..| ||.|   . |..|. ||.
GTIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGE-NRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPF

F
|
F
Kinase 26470.AA Pkinase 30-286 29 1.7e-97 335.03 Pfam 1-293 (293) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-293/293
Sequence Identity: 29% (88 aa)

FTLLKMIGEGAYAKVYLVRKLDNQKVYALKILKKKKIQELGQQHRVI-LEKDILANIESHPFIIKLHYSFQNDTKLFFALDFCPGG----ELFSILS--R
..... ||.|....||. .. ...|..|.||.||... .  .|...   |  |.... .||.|..|...|...... . ...|.||    .||...|  |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

KHKF--DEEQCRFYAAQIVLAIEHLHKHNIIYRDLKPENVILDKEGYI----RISDFGLSKD--NIEDQTAFSVCGTPEYLAPEILN-NSGHGKPVDWWA
. .|  .|..|.||. ||. ..|..|...||.|||||||. .|..|.|    .|.||||.|   .  .. . ..||||.|.|||... ....|..||.|.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGNLIYEMLTGLPPFYVE-----NNREELFKKIKYTEITIPSYFS---------------------KACKDLLTRLFLKNPYQRLGSNGAEEIKDHPWF
.| ..||||.| |||. .     ..  .....|.....  ... .                     ..|||...... |.|..|..   ||.|. ||||
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF
Kinase 26470.AA Ciliate-E2-Unclassified 30-286 27 3.6e-96 325.82 In-house 1-352 (352) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-352/352
Sequence Identity: 27% (98 aa)

FTLLKMIGEGAYAKVYLVRKLDNQKVYALKILKKKKIQELGQQHRV---ILEKDILANIE------------------SHPFIIKLHYSFQNDTKLFFAL
....| ||.|...|||.... .....||.|..||..|.   |. ..   ..|.... |..                   ||||.|..| ||.. .... .
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

DFCPGGELFSILSRKHK-----------------FDEEQCR-----FYAAQIVLAIEHLHKHN-IIYRDLKPENVILDKEG---YIRISDFGLSKDNIED
..|.||.|. ... ..|                 |.|.|..     ||.|||....|.||. | ||.||.||||...|..|   ||.|.|||.|| ....
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

----------------QTAFSVCGTPEYL----APEILNNSGHG----KPVDWWALGNLIYEMLTGLPPFYVENNRE---------------ELFKKIKY
                | . ..||||.|.    |||.| . ...    . .|.|.|| ..||||.| .||| .|  .               .|...|| 
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

TEITIPS--------YFSKACKDLLTRLFLKNPYQRLGSN-GAEEIKDHPWF
 .| .|.          |. .||....|. |..  ..... ..|.|. ||||
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 26470.AA S_TK_X 287-345 25 7.5e-15 56.58 SMART 1-79 (79) Show / Hide 
Range on Protein: 287-345
Range on HMM: 1-79/79
Sequence Identity: 25% (20 aa)

TDVDWDKMLQ--KKYNAPFVPKLK----NEIDVSNFDDYFVHQPLNESYQDN------QIYH--------EFSNFSFVN
 ..|||| ..  |.. .||.||.|    ...|.||||. |  ..  .. .|       .           .| .|..|.
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 26470.AA TyrKc 30-281 22 4.8e-13 -11.77 SMART 1-280 (280) Show / Hide 
Range on Protein: 30-281
Range on HMM: 1-280/280
Sequence Identity: 22% (64 aa)

FTLLKMIGEGAYAKVYLVRKLDNQKVYALKILKKKKIQELGQQHRVILEKDILANI-ESHPFIIKLHYSFQND-------TKLFFALDFCPGGELFSIL-
 ||.|..||||. .||. .    ..| | | ||. .      .   . |  |. ..  .|| |..|.     .         |.  . ..|.| | . | 
ITLGKKLGEGAFGEVYKGTWK--IQV-AVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

SRKHKFDEEQCRFYAAQIVLAIEHLHKHNIIYRDLKPENVILDKEGYIRISDFGLSKDNIED------QTAFSV----CGTP----EYLAPEILNNSGHG
....|.  ..   .. ||    |.||..|.| |||   |. ..... ..|||||||.|  .|      .   ..    .|        .||| .| .   
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

KPVDWWALGNLIYEMLT-GLPPFYVE----NNREELFKKIKYT-EITIPSY--------FSKACKDLLTRLFLKNPYQRLGSNGAEEIK
   | |. | ...|..| | .| . .     . .|.....|      .| .         ...  .. ..    .| .|   .   |. 
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 26470.AA Pkinase_C 306-347 26 4.3e-07 28.29 Pfam 1-46 (46) Show / Hide 
Range on Protein: 306-347
Range on HMM: 1-46/46
Sequence Identity: 26% (12 aa)

KLKNEIDVSNFDDYFVHQPLNESY----QDNQIYHEFSNFSFVNSL
..|...|.||||. |  .| ....      ..  ..| .|..||. 
QVKSPTDTSNFDPEFTDEPPMDTPPDWRMSSGDQEPFRGFTYVNPD
Kinase 26470.AA Pkinase_Tyr 30-178 25 3e-06 21.59 Pfam 1-160 (270) Show / Hide 
Range on Protein: 30-178
Range on HMM: 1-160/270
Sequence Identity: 25% (41 aa)

FTLLKMIGEGAYAKVYLVRKL-----DNQKVYALKILKKKKIQE-LGQQHRVILEKDILANIESHPFIIKLHYSFQ-NDTK--LFFALDFCPGGELFSIL
 |..|..||||. .||. .       ....| | |.|| .  .| .  .   . |  |. .. .|| |..|.      .    ..  . ..|.| | . |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPV-AVKMLKEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

SR----KHKFDEEQCRFYAAQIVLAIEHLHKHNIIYRDLKPENVILDKEGYIRISDFGLSKD
 .    |.... ..   ...||  . |.|. .|.| |||   |. ..... ..|.||||..|
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD