26293

Species: Tetrahymena
Alias: 912, 26293, TTHERM_00752250, 122.m00095, PreTt26293
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: AGC
Family: AktR

Sequence

Name Sequence Type Origin Length Description Download
26293.AA Protein None 1598 None Fasta, JSON
26293.kin_dom Protein Kinase Domain None 260 None Fasta, JSON
26293.NA RNA None 4797 None Fasta, JSON

Protein domain

Protein domains of 26293.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 26293.AA AktR 577-836 51 6.30000000001e-169 567.5 In-house 1-268 (268) Show / Hide
Range on Protein: 577-836
Range on HMM: 1-268/268
Sequence Identity: 51% (139 aa)

FHFIKCVGMGGFSRVYLVQKK-DNGKMYALKLIEKKFILTNKKEQIVQNERNIMTMMQGHPFLLQLDYAFESKNYIAFAMEYCAGGEMFYHLRKIKKMTE
||..|| |.|.|..||||||| ||.|.||.|.| ||.|  .........||||| |.. |||. .| |.|..|... |.||||.|||.|.||.|.||..|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

EQARFYFIEICLGIDYLHDR-HIIYRDIKPENILLDIDGHIRIGDFGLSK--PDMDDNEFAYSFCGSPEYMAPEMLLK-VGHAYPVDHYTLGALLYELVT
||||||| .|.|...|||.. .|||||.|||||||| |||..|.||||||  ..|...|.||||||.||||||||..| .|| ..||....|...||.||
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GLPPFYSQITEEIYKSILSED-LTFPDHVNLSSELKNLLR-GLLTKHPLQRLG-QNMGTKEILSHPWC
|.||||.. .......|.... . ||.....||..|.|.  .|| |.| .||| ...|..|| ||||.
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF

Kinase 26293.AA AGC 577-836 30 2.1e-166 434.31 In-house 1-395 (395) Show / Hide
Range on Protein: 577-836
Range on HMM: 1-395/395
Sequence Identity: 30% (123 aa)

FHFIKCVGMGGFSRVYLVQKK------DNGKMYALKLIEKKF-ILTNK--KEQIVQNE------------RNIMTMMQG---------HPFLLQ-LDYAF
|.|.|..| |.|..||||.||      |.||.||.| ..||  |. .|  ... ...|            |||......         |||. . | |.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ESKNY--IAFAMEYCA---------GG-EMFYHLR---KIKKMTEEQARFYFIE-------ICLGIDYLHD-RHIIYRD-IKPENILLDIDGHIRIGDFG
..|..  . | |||.          || |.|.||.   | ....||.||||. |       |.|...|||. ..||.|| .|||||||| ||||.. |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKPDMDDN--------------------------------------------------EFAYSFCG--SPEYMAPEMLLKVGHAYPVDHYT--LGALLY
|.|  |.|.                                                  . ...|||  .|||||||.|    . ...| ..  ||.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELVTGLPPFYSQ----------ITEEIYKSIL------SEDLTFPDH--------VNLSSELKNLLRGLLTKHPLQRLGQNM------GTKEILSHPWC
|..||.||||..            .|....|.      .....||..        ...|.|.|.|...||.|.| .||| .       |..|| .||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase 26293.AA Akt 577-836 44 2.8e-124 399.23 In-house 1-264 (264) Show / Hide
Range on Protein: 577-836
Range on HMM: 1-264/264
Sequence Identity: 44% (118 aa)

FHFIKCVGMGGFSRVYLVQKKDNGKMY-ALKLIEKKFILTNKKEQIVQNERNIMTMMQGHPFLLQLDYAFESKNYIAFAMEYCAGGEMFYHLRKIKKMTE
| |.|. | | | .|.||.|||..|.| |.| . |. |. ... . .. ||||  ... |||. .| |.| ..... | |.|| ||| ||||.. ....|
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCN-HPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE

EQARFYFIEICLGIDYLHDRHIIYRD-IKPENILLDIDGHIRIGDFGLSKPD-MDDNEFAYSFCGSPEYMAPEMLLKVGHAYPVDHYT-LGALLYELVTG
..||||  || |.|..|| . |||||  ||||||.| ||||.. ||||.| . . |.. ...|||.|||.|||.|...||  .|| .. ||...||. .|
DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG

LPPFYSQITEEIYKSILSEDLTFPDHVNLSSELKNLLRGLLTKHPLQRLG-QNMGTKEILSHPWC
.||||.|  .. .| |..... |||  ..| | |.|..|||.| | .|||  . ...|| .||| 
RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF

Kinase 26293.AA SGK 577-836 40 4.1e-118 366.48 In-house 1-283 (283) Show / Hide
Range on Protein: 577-836
Range on HMM: 1-283/283
Sequence Identity: 40% (117 aa)

FHFIKCVGMGGFSRVYLVQKKDN------------------GKMYALKLIEKKFIL-------TNKKEQIVQNER-NIMTMMQGHPFLLQLDYAFESKNY
|.|.| .| |.| .||.|..||                   .|.||.|.. |. |.        .|..  .. || .|.  |  |||. .| |||  | .
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMK-HPFIVNLHYAFQTKWK

IAFAMEYCAGGEMFYHLRKIKKMTEEQARFYFIEICLGIDYLHDRHIIYRDIKPENILLDIDGHIRIGDFGLSKPDMDDNEFAYSFCGSPEYMAPEMLLK
  | |.|  ||||||||.. |.  | .||||  || . ..|||.  ||||| |||||||| .||... ||||.| .. .|..  .|||.|||.|||.|.|
LYFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRK

VGHAYPVDHYTLGALLYELVTGLPPFYSQITEEIYKSILSEDLTFPDHVNLSSELKNLLRGLLTKHPLQRLGQNMGTKEILSHPWC
 .|   || . ||..|||. .|||||||. ... |  |....| .|  .  |.. . |. |||.| | .||| . .  || .||. 
QPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQM--SNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF

Kinase 26293.AA RSK 580-836 41 9.7e-99 334.34 In-house 1-278 (278) Show / Hide
Range on Protein: 580-836
Range on HMM: 1-278/278
Sequence Identity: 41% (114 aa)

IKCVGMGGFSRVYLVQKK---DNGKMYALKLIEKKFILTNKK-EQIVQNERNIMTMMQGHPFLLQLDYAFESKNYIAFAMEYCAGGEMFYHLRKIKK---
.|  | ||.  |.|..|.   |.|. || | ..|. | ...|    .  ||||. . |.|||. .| |||. . ..   |||| |||.|.||.| |    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

MTEEQARFYFIEICLGIDYLHDRHIIYRDIKPENILLDI---DGHIRIGDFGLSKP-DMDDNEFAYSFCGSPEYMAPEMLL----KVGHAYPVDHYTLGA
..|. |.||. || | ...||...||.||.||||||.|    .|||.. |||..|  . |.|. ...||.. ||||||||     ..||   .| ..||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LLYELVTGLPPFYS---QITEEIYKSILSED--LTFPDHVNLSSELKNLLRGLLTKHPLQRLG-QNMGTKEILSHPWC
|.||. || |||..   .  .|| | |.. .  ||.|   .|| | |.|.|..|...| .|||   ....||..||| 
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase 26293.AA RSK-Unclassified 577-836 36 5.8e-96 301.91 In-house 1-283 (283) Show / Hide
Range on Protein: 577-836
Range on HMM: 1-283/283
Sequence Identity: 36% (103 aa)

FHFIKCVGMGGFSRVYLVQKKDNGKMYALKLIEKKFILTNKKEQIVQNERNIMTMMQGHPFLLQLDYAFESKNYIAFAMEYCAGGEMFYHLR--KIKKMT
|  .. .| | | .||||.|||  ..||.|  .|. ..  .| . |  |.||| . . |||  .| ..| .. |    |||| ||..| ||   | |...
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTN-HPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFC

EEQARFYFIEICLGIDYLHDRHIIYRDIKPENILLDIDGHIRIGDFGLSKPD---------------------MDDNEFAYSFCGSPEYMAPEMLLKVGH
|...|||  |. .   ||| | .|||| ||.||.|. .||..  ||.||.                       .|.   . ||||. ||.||||.   ||
EDDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGH

AYPVDHYTLGALLYELVTGLPPFYSQITEEIYKSILSEDLTFPDHVNLSSELKNLLRGLLTKHPLQRLGQNMG-TKEILSHPWC
   || .||| ..||.  |.||.|   ..|... |. ... ||.   .| . . |.. ||.. |  |||  ||   .|  ||  
TKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF

Kinase 26293.AA S_TKc 577-836 31 6.9e-88 299.21 SMART 1-231 (231) Show / Hide
Range on Protein: 577-836
Range on HMM: 1-231/231
Sequence Identity: 31% (86 aa)

FHFIKCVGMGGFSRVYLVQKKDNGKMYALKLIEKKFILTNKKEQIVQNERNIMTMMQGHPFLLQLDYAFESKNYIAFAMEYCAG--GEMFYHLRKIKK--
..... .| |.|..||....|. |. .|.| |           . ...|..|. .  .||.. .| ..|.. ... . |||| |  |..| ...| ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----MTEEQARFYFIEICLGIDYLHDRHIIYRDIKPENILLDIDGHIRIGDFGLSKPDMDDNEFAYSFCGSPEYMAPEMLLKVGHAY-PVDHYTLGALLY
    ..| .||||. .||....|.|...||.||.||||||||   || |.||||..         ..|||.|.|||||.|   |. . ..| . .| .||
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELVTGLPPFYSQITEEIYKSILSEDLTFPDHVNLSSELKNLLRGLLTKHPLQRLGQNMGTK---EILSHPWC
|...| |||.    ....| |.            |.|.|...|..|.| | .|..     .   .| .||| 
EMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 26293.AA RSK 577-836 35 2.9e-84 286.23 In-house 1-271 (271) Show / Hide
Range on Protein: 577-836
Range on HMM: 1-271/271
Sequence Identity: 35% (96 aa)

FHFIKCVGMGGFSRVYLVQKK---DNGKMYALKLIEKKFILTNKKEQIVQNERNIMTMMQGHPFLLQLDYAFESKNYIAFAMEYCAGGEMFYHLRKIKKM
. ...| | | || ||...|.   |... || | |.|. .    . .   .||.|.   . |||  .| |.|..  ..   |. ..||..| .| | | .
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGH-HPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMF

TEEQARFYFIEICLGIDYLHDRHIIYRDIKPENILLDID----GHIRIGDFGLSKPDMDDNEFAYSFCGSPEYMAPEMLLKVGHAYPVDHYTLGALLYEL
.|. ..||  || |  .|||   |..|| ||||||.| .    |||.| |||..|   |.|. ...||.. .|||||.| . ||   .| . .|.|.|| 
SEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEM

VTGLPPFYSQITEEIYKSILSEDLTF-----PDHVNLSSELKNLLRGLLTKHPLQRLGQ-NMGTKEILSHPWC
 || .||...  ..    |.  .|       .   ..| | | |||..|.  | .|||    |...|..||| 
LTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF

Kinase 26293.AA Ciliate-E2-Unclassified 577-836 29 6.6e-83 281.74 In-house 1-352 (352) Show / Hide
Range on Protein: 577-836
Range on HMM: 1-352/352
Sequence Identity: 29% (103 aa)

FHFIKCVGMGGFSRVYLVQKKDNGKMYALKLIEKKFILTNKKEQIV---------QNERN---------IMT---MMQGHPFLLQLDYAFESKNYIAFAM
...||. | |||. ||..|.|.... ||.| . |. |   |. . .          |...         ||     .  |||.. . |.|..|..| . |
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYCAGGEMFYHLRKIKK-----------------MTEEQAR-----FYFIEICLGIDYLHDRH-IIYRDIKPENILLDIDG---HIRIGDFGLSK-PDMD
||| ||.......| ||                  ||.||.     ||| .|..|..|||  . ||.|||||||||.| .|   .|.| |||.|| .. .
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

--------------DNEFAYSFCGSPEYM----APEMLLKVGHA----YPVDHYTLGALLYELVTGLPPFYS-QITE---------------EIYKSILS
              ... ...|||.|.||    |||.| . ..     | .| ..|| .|||...| .|||. . ..               ..|. |. 
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

EDLTFP------DHVNLSSELKNLLRGLLTKHPLQRLGQNMGTKEILSHPWC
 .. ||      .. ..| | |.... || | .  ....... ..|| ||| 
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 26293.AA PKA 577-836 39 1e-82 281.1 In-house 1-263 (263) Show / Hide
Range on Protein: 577-836
Range on HMM: 1-263/263
Sequence Identity: 39% (105 aa)

FHFIKCVGMGGFSRVYLVQKKDNGKMYALKLIEKKFILTNKKEQIVQNERNIMTMMQGHPFLL-QLDYAFESKNYIAFAMEYCAGGEMFYHLRKIKKMTE
| .|. .|.| | ||.|...|..|. ||.| . |  |   | .. | ||.||.. .. |||.  .... |   .|. . |||..|||||..||| .. ..
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIK-HPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSN

EQARFYFI-EICLGIDYLHDRHIIYRDIKPENILLDIDGHIRIGDFGLSKPDMDDNEFAYSFCGSPEYMAPEMLLKV-GHAYPVDHYTLGALLYELVTGL
 .|.||   .|.| ..|||  .||||| ||||||.| .||| |.||| .|  .||    .. || |||.|||...   ||  .||  .|| | ||...| 
PHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAK-KVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGY

PPFYSQ--ITEEIYKSILSEDLTFPDHVNLSS-ELKNLLRGLLTKHPLQRLGQNM-GTKEILSHPWC
||||     . .||. |.. .. || |..     .| |.. ||.. . .|.|    |.  |  |.| 
PPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF

Kinase 26293.AA Pkinase 577-836 31 1.4e-80 278.82 Pfam 1-293 (293) Show / Hide
Range on Protein: 577-836
Range on HMM: 1-293/293
Sequence Identity: 31% (94 aa)

FHFIKCVGMGGFSRVYLVQKKDNGKMYALKLIEKKFILTNKKEQIVQ-NERNIMTMMQGHPFLLQLDYAFESKNYIAFAMEYCAGG----EMFYHLR--K
.|.....| |.|..||. ..|..||..|.| |.|. .  .|... .  .|  || .. .||. ..| ..||.|..| . |||| ||    . | ...  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

IKKM--TEEQARFYFIEICLGIDYLHDRHIIYRDIKPENILLDIDGHI----RIGDFGLSKPD-MDDNEFAYSFCGSPEYMAPEMLL-KVGHAYPVDHYT
 ...  .|....||. .|. |..|.|.. ||.||.||||||.| .|||    .|.||||.|      |. ...|||.|.||||| ..   .. ..|| . 
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGALLYELVTGLPPFYSQ------ITEEIYKSILSEDLTFPDH-------------------VNLSSELKNLLRGLLTKHPLQRLGQNMGTKEILSHPWC
.| .|||...| |||...         .... |.. .| |.                     .|.|.|.| .....|.| | .|..     ..|| ||| 
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT----AEQILQHPWF





Kinase 26293.AA Ciliate-E2 577-836 26 9.8e-79 267.89 In-house 1-365 (365) Show / Hide
Range on Protein: 577-836
Range on HMM: 1-365/365
Sequence Identity: 26% (101 aa)

FHFIKCVGMGGFS-----RVYLVQK------------------KDNGKMYALKLIEKKFILTNKKEQIVQ----------NERNIMTMMQGHPFLLQLDY
. |||. | |.|.     .|..|||                  |...|.||.| ..|. |   |.|. .           ||.||.  .. ||..... .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLN-HPNIIKMYE

AFE--SKNYIAFAMEYCAGGEMFYHLRKI-----------KKMTEEQARFYFIEICL---------------GIDYLHDRH-IIYRDIKPENILLDIDGH
.|.  ..|.| . |||| ||..|.....            |..||....... .|.                .. ||| .. ||.|||||||||.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IRIGDFGLSKPDMDDNE-------------------------------FAYSFCGSPEYMAPEMLLKVG---------HAYPVDHYTLGALLYELVTGLP
| | ||||||   |||.                                ....||.|.|||||.| . .         . | .| . || .|||...| |
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFYSQITEEIYKSILSEDLTFP----------------DHVNLSSELKNLLRG----LLTKHPLQRLGQNMGTKEILSHPWC
||        .. |.  .. ||                .. ..| | |.|..     .| | | .|..   | ..|| ||| 
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT---GWEQILNHPWF

Kinase 26293.AA TyrKc 577-830 19 2.2e-10 -54.67 SMART 1-280 (280) Show / Hide
Range on Protein: 577-830
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

FHFIKCVGMGGFSRVYLVQKKDNGKMYALKLIEKKFILTNKKEQIVQNERNIMTMM-QGHPFLLQLDYAFESK-------NYIAFAMEYCAGGEMFYHLR
 ...|  | | | .||. . |    . | | . .        ..   .| .||..    || ...|  .  ..         .   |||...|    .||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KIKK-MTEEQARFYFIEICLGIDYLHDRHIIYRDIKPENILLDIDGHIRIGDFGLSKPDMDD-----NEFAYSFCG--SPE------YMAPEMLLKVGHA
| ..  . ..   . . |. | .|||....| ||.   |.|.. .....|.|||||.   ||     ..  |.  .  .         |||| .      
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI------

YPVDH-YTL-------GALLYELVT-GLPPFYS-----QITEEIYKSILSE-DLTFPDH------VNLSSELKNLLRGLLTKHPLQRLGQNMGTKEI
   .. .|        | ...|. | | .| .         .|... . .   .  |..      |  ..|. .. .      | .|   .   ...
--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 26293.AA Pkinase_Tyr 655-724 29 5e-06 21.02 Pfam 86-159 (270) Show / Hide
Range on Protein: 655-724
Range on HMM: 86-159/270
Sequence Identity: 29% (22 aa)

MEYCAGGEMFYHLRK----IKKMTEEQARFYFIEICLGIDYLHDRHIIYRDIKPENILLDIDGHIRIGDFGLSK
|||...| .  .|||     .. | ..   . ..|. | .||.....| ||.   |.|.. .....|.||||..
MEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR