Gene 26010 (Tetrahymena)
26010
Sequence
Protein domains of 26010.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
---|---|---|---|---|---|---|---|---|---|
Kinase | 26010.AA | AGC | 40-298 | 30 | 3.6e-169 | 441.62 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 40-298 Range on HMM: 1-395/395 Sequence Identity: 30% (121 aa) FELLNVIGEGKFGTVLLVKKK------DSGKLFAMKIIK---KSIIRKRQFAHRIIQE------------KDILAFCN----------NNFMTK-LHYSF ||.| |||.| ||.| ||.|| |.||..|||..| | .|.|.. .... | ..||. || . | .| ||||| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QNQNN--LFLILDYCS---------GG-DLFNYIS---KKNTISEKDAKFYAAQ-------IVLMLEYLHS-QNIVYRD-LKPENILIEKNGYLKLGDFG |.... |.....|.. || .|| .. |. . .|. |.||||. ||| |||||| ..|..|| |||||||. ..|..|| ||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG YARQNMDS---------------------------------------------------IEAKSVCG--TPHYFPPEMITREGHGKPVDWWA--LGCVIY . ..|.. ... || ||.| .||.. .||..|||. |||..| LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY EMVFGATPFDDSN----------QKILFDRIK------NSPVIFENDKN------KKVSNNFKDIVNKLLKKNQNERLGTAS-------IEEIKSHPWF ||..| .|| . | .. .|..|. | .| | .... ...|.. ||...|||.|. ..|||. .||||.|||| EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
|||||||||
Kinase | 26010.AA | AktR | 40-298 | 49 | 9.5e-162 | 543.65 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 40-298 Range on HMM: 1-268/268 Sequence Identity: 49% (132 aa) FELLNVIGEGKFGTVLLVKKK-DSGKLFAMKIIKKSIIRKRQFAHRIIQEKDILAFCNNN-FMTKLHYSFQNQNNLFLILDYCSGGDLFNYISKKNTISE |......|.|.||.| ||.|| |..|..|||.|||. |..|...|..|.|..|...|.|. |. ||||.||....||.|..|| ||.||....||...|| FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE KDAKFYAAQIVLMLEYLHSQ-NIVYRDLKPENILIEKNGYLKLGDFGYAR-QNM--DSIEAKSVCGTPHYFPPEMITR-EGHGKPVDWWALGCVIYEMVF ..|.||.|||.|.|||||.. ||.||||||||||....|..|..|||... |.| .. .|.|.||||.|..|||||. .||.|.|||||.|..|||||. EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT GATPFDDSNQKILFDRIKNSPVIFENDKNKKVSNNFKDIVN-KLLKKNQNERLG--TASIEEIKSHPWF | .||...||...|..||... ..........|...||... |||.||.|.||| ....||||||||| GCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
|||||||||
Kinase | 26010.AA | Akt | 40-298 | 47 | 3e-139 | 447.84 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 40-298 Range on HMM: 1-264/264 Sequence Identity: 47% (126 aa) FELLNVIGEGKFGTVLLVKKKDSGKLF-AMKIIKKS-IIRKRQFAHRIIQEKDILAFCNNNFMTKLHYSFQNQNNLFLILDYCSGGDLFNYISKKNTISE |..|.|.| | || |.||||||..|.. |||..||. || |.|..| ...|. || ||..| ..||||||.|..|....|||.||.||.....|...|| FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEH-TKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE KDAKFYAAQIVLMLEYLHSQNIVYRD-LKPENILIEKNGYLKLGDFGYARQN-MDS-IEAKSVCGTPHYFPPEMITREGHGKPVDWWA-LGCVIYEMVFG . |.||.|.|.| .|.|||.||.||| |||||||. |.|...| ||| ...| . ..|..|||| | .||.. ||.|.||||. ||||.||| .| DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG ATPFDDSNQKILFDRIKNSPVIFENDKNKKVSNNFKDIVNKLLKKNQNERLG-TAS-IEEIKSHPWF . || . ... .|. |||.|| | . ...|.. ||....||.|. ..||| . . ..|||.|||| RPPFYNQDHHQMFKKIKNQPVKFPDK--DWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
|||||||||
Kinase | 26010.AA | PKA | 40-298 | 43 | 2.7e-122 | 412.58 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 40-298 Range on HMM: 1-263/263 Sequence Identity: 43% (116 aa) FELLNVIGEGKFGTVLLVKKKDSGKLFAMKIIKKSIIRKRQFAHRIIQEKDILAFCNNNFMT-KLHYSFQNQNNLFLILDYCSGGDLFNYISKKNTISEK ||.....| | ||.| |...|.||. .|||..||. | .. .... || || ... | |. ..||. ..|.....|..||..| |. |. |.. FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP DAKFYAA-QIVLMLEYLHSQNIVYRDLKPENILIEKNGYLKLGDFGYARQNMDSIEAKSVCGTPHYFPPEMITRE-GHGKPVDWWALGCVIYEMVFGATP .|||||| ||||.|||||||||.||||||||||| |||..|..||| | ...|. . ...|||| |..||.|... ||||.|||||||..||||..| .| HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFA-KKVDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP FDDS--NQKILFDRIKNSPVIFENDKNKKVSNNFKDIVNKLLKKNQNERLGTASI--EEIKSHPWF | |. .. ....| | . |.. .... | ||| ..||| .. ..|.|. . . || |.|| FYDHNRDPMQIYEKICNGKIKFPRHFDSDA-NYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF |
|||||||||
Kinase | 26010.AA | SGK | 40-298 | 38 | 1.1e-117 | 365.07 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 40-298 Range on HMM: 1-283/283 Sequence Identity: 38% (110 aa) FELLNVIGEGKFGTVLLVKKKDS------------------GKLFAMKIIKKSIIR-------KRQFAHRIIQEK-DILAFCNNNFMTKLHYSFQNQNNL |..|.|||.| || |..||.|| .|..|||...| |. |. . | |. .|| . | .|||.||.. | FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL FLILDYCSGGDLFNYISKKNTISEKDAKFYAAQIVLMLEYLHSQNIVYRDLKPENILIEKNGYLKLGDFGYARQNM-DSIEAKSVCGTPHYFPPEMITRE .. .|| ||..|... . . .| |.||||.||. |||||||.|.|||||||||| |...| ||| . ... .. . .. |||| | ||.. . YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ GHGKPVDWWALGCVIYEMVFGATPFDDSNQKILFDRIKNSPVIFENDKNKKVSNNFKDIVNKLLKKNQNERLGTA-SIEEIKSHPWF .|.. |||| |||| ||| .|. || . | ....| | |.| . . .|| .|. . ||.|.. .||||. .|||.||.| PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIP----PQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF |
|||||||||
Kinase | 26010.AA | S_TKc | 40-298 | 36 | 9.69999999999e-105 | 355.18 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 40-298 Range on HMM: 1-231/231 Sequence Identity: 36% (98 aa) FELLNVIGEGKFGTVLLVKKKDSGKLFAMKIIKKSIIRKRQFAHRIIQEKDILAFCNNNFMTKLHYSFQNQNNLFLILDYCSG--GDLFNYISKKNT--- .|.|..||.| ||.| ....|..|...|.|||| .|..| .|| . . ||...||. ..|.....||.| |||| || |... YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---ISEKDAKFYAAQIVLMLEYLHSQNIVYRDLKPENILIEKNGYLKLGDFGYARQNMDSIEAKSVCGTPHYFPPEMITREGHGK-PVDWWALGCVIYEM ..| .|.||..||.. |||.||..|..|||||||||. . .|..||| ||| ...||||.| .||.. |.|| ..|||..||..||| RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM VFGATPFDDSNQKILFDRIKNSPVIFENDKNKKVSNNFKDIVNKLLKKNQNERLGTASIEE----IKSHPWF . | .||. ... .|..|. | .||...|.|.|. ..|.. . . ||.|||| LCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
|||||||||
Kinase | 26010.AA | RSK | 43-298 | 39 | 1.5e-104 | 353.66 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 43-298 Range on HMM: 1-278/278 Sequence Identity: 39% (109 aa) LNVIGEGKFGTVLLVKKK---DSGKLFAMKIIKKSIIRKRQF-AHRIIQEKDILAFCN-NNFMTKLHYSFQNQNNLFLILDYCSGGDLFNYISKKNT--- | | |.| .| | |..|. |.|...|||..||. |..|| . . .| .||. |. | .|||.|| . |.||..||.||.|| ..|. . LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC ISEKDAKFYAAQIVLMLEYLHSQNIVYRDLKPENILIEK---NGYLKLGDFGYARQ-NMD-SIEAKSVCGTPHYFPPEMIT----REGHGKPVDWWALGC .||..|.||.|.||| .|.||.| |..||||||||| . .| .|| ||| ..| . | . ... |.| .| .|||.. ..||.| .||| ||. FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV VIYEMVFGATPFDD---SNQKILFDRIKNSPVIFENDKNKKVSNNFKDIVNKLLKKNQNERLG--TASIEEIKSHPWF ..||| .|..|| .|.| ...||.. .. . ....|...||...|.|... . ||| .||||.|||| LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
|||||||||
Kinase | 26010.AA | RSK-Unclassified | 40-298 | 37 | 3.7e-102 | 321.74 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 40-298 Range on HMM: 1-283/283 Sequence Identity: 37% (106 aa) FELLNVIGEGKFGTVLLVKKKDSGKLFAMKIIKKSIIRKRQFAHRIIQEKDILAFCNNNFMTKLHYSFQNQNNLFLILDYCSGGDLFNYIS--KKNTISE |. || | || | ||.|||. ...|||. .|. . ... ... |..|.| | | .| .||| | |.|...|| |||.| |. ..| FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE KDAKFYAAQIVLMLEYLHSQNIVYRDLKPENILIEKNGYLKLGDFGYARQN----------------------MDSIEAKSVCGTPHYFPPEMITREGHG |..|||. ... ||||| . ..||||||.||. .. | .| ||. | .. ..| ||| | |||| | ||. DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT KPVDWWALGCVIYEMVFGATPFDDSNQKILFDRIKNSPVIFENDKNKKVSNNFKDIVNKLLKKNQNERLGTASI--EEIKSHPWF | |||| || |.||| || .|. |. .| | .| | .| . .||| .| . |||..| ||| . ..|| || | KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHD--SYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF |
|||||||||
Kinase | 26010.AA | Ciliate-E2-Unclassified | 40-298 | 29 | 8.9e-96 | 324.49 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 40-298 Range on HMM: 1-352/352 Sequence Identity: 29% (105 aa) FELLNVIGEGKFGTVLLVKKKDSGKLFAMKIIKKSIIRKRQFAHR---------IIQEKD-------------ILAFCNNNFMTKLHYSFQNQNNLFLIL .... .||.| ||.| ....|. ....|||..||..|.|.. . ....| || ... | |..| ||...|..... YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM DYCSGGDLFNYISKKNT-----------------ISEKDAK-----FYAAQIVLMLEYLHSQN-IVYRDLKPENILIEKNG---YLKLGDFGYAR----- .|| ||||..||.|... ..|. || ||.|||.. |||||..| |..||.||||||. .|| |.|. ||| .. EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN -----------QNMDSIEAKSVCGTPHYF----PPEMITREGHG----KPVDWWALGCVIYEMVFGATPFDDSNQKI----------------LFDRIKN |. .. .....|||| | .||.. ..... . .|.|.||...|||.|| ||.| |... |.. ||. NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ SPVIFENDKN----KKVSNNFKDIVN----KLLKKNQNERLGTASIEEIKSHPWF .. | . .. |..|.. ||..| |.||||.|.|. ..|.|. |||| KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI---TFEQILNHPWF |
|||||||||
Kinase | 26010.AA | Ciliate-E2 | 40-298 | 26 | 1.3e-90 | 307.38 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 40-298 Range on HMM: 1-365/365 Sequence Identity: 26% (102 aa) FELLNVIGEGKFG-----TVLLVKK------------------KDSGKLFAMKII-------KKSIIRKRQFAH----RIIQEKDILAFCNNNFMTKLHY ......||.| || .| .|.| |. .|..||||. .|..|. . . .| .|| || . |... |... YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKI-NEKNILEQLNHPNIIKMYE SFQ--NQNNLFLILDYCSGGDLFNYISKKNTIS-----------EKDAK---------------FYAAQIVLMLEYLHSQN-IVYRDLKPENILIEKNGY .|| ..||..|...||.||||| || .... . || .| ||.|.|.| ||||||.| |..||.||||||. CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----- LKLGDFGYARQNMDSIEAKS--------------------------------VCGTPHYFPPEMITREG---------HGKPVDWWALGCVIYEMVFGAT .|. |||..... |. . .. .||||.| .||.. ... ... .|.|.||...|||.|| . IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP PFDDSNQKILFDRIKNSPVIFEND--------------KNKKVSNNFKDIVNK----LLKKNQNERLGTASIEEIKSHPWF || .. ||. .. | . ..||.|.. ||. .| .|.|....|.. ..|.|. |||| PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF |
|||||||||
Kinase | 26010.AA | Pkinase | 40-298 | 32 | 4.3e-90 | 310.4 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 40-298 Range on HMM: 1-293/293 Sequence Identity: 32% (98 aa) FELLNVIGEGKFGTVLLVKKKDSGKLFAMKIIKKSIIRKRQFAHRII-QEKDILAFCNNNFMTKLHYSFQNQNNLFLILDYCSGG----DLFNYIS--KK .... .||.| ||.| . ..|..||..|.|||||. ... . ... .| |.. .| . .|...|.. ... ....|| || ||| ||| .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH NTI--SEKDAKFYAAQIVLMLEYLHSQNIVYRDLKPENILIEKNGYL----KLGDFGYARQ--NMDSIEAKSVCGTPHYFPPEMIT-REGHGKPVDWWAL ... ||...|||. ||. |||.||..|..|||||||||| .||.. |..||| |.| . . ....||||.| .|| | ....|..||.|.. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GCVIYEMVFGATPFDDS------NQKILFDRIKNSPVIFENDKNKKVS-----------------NNFKDIVNKLLKKNQNERLGTASIEEIKSHPWF ||..|||..| .||... .|. ...||. |. |. .. .| ..||.....|.|. ..|.. .|.|. |||| GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF |
|||||||||
Kinase | 26010.AA | RSK | 40-298 | 37 | 1.1e-87 | 297.56 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 40-298 Range on HMM: 1-271/271 Sequence Identity: 37% (102 aa) FELLNVIGEGKFGTVLLVKKK---DSGKLFAMKIIKKSIIRKR-QFAHRIIQEKDILAFCNNNFMTKLHYSFQNQNNLFLILDYCSGGDLFNYISKKNTI .||. .||.| |. | ..||. |.....|||||||. . . . . | .||. . | ||||.|| . ....|.| . ||||| ..|. YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR--VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMF SEKDAKFYAAQIVLMLEYLHSQNIVYRDLKPENILIEKN----GYLKLGDFGYARQNMDSIE-AKSVCGTPHYFPPEMITREGHGKPVDWWALGCVIYEM ||...|||.| | | .|||||| ||.|||||||||. | .|. ||| | | | . ... |.| | ||.. | ||.. .||| .| . ||| SEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEM VFGATPFDDSNQKILFDRIKNSPVIF---ENDKNKKVSNNFKDIVNKLLKKNQNERLGT--ASIEEIKSHPWF |.||| . . ... |.. .. ..| || . ..|. . . |||. .|.||.|||| LTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF |
|||||||||
Kinase | 26010.AA | TyrKc | 40-275 | 20 | 4.8e-12 | -27.97 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 40-275 Range on HMM: 1-280/280 Sequence Identity: 20% (60 aa) FELLNVIGEGKFGTVLLVKKKDSGKLFAMKIIKKSIIRKRQFAHRIIQEKDILAFCN-NNFMTKL-----------HYSFQNQ------NNLFLILDYCS .|. ..||| ||.| . . | | | .|.. . .|.. . |.|| . | . |.... |.. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMP GGDLFNYI-SKKNTISEKDAKFYAAQIVLMLEYLHSQNIVYRDLKPENILIEKNGYLKLGDFGYARQNMDS------IEAKSV----CGTP----HYFPP .||| .|. ....... || .. || |||||.|.. ||| |.|. .|. | .||| .| | . ... .| .| HGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP EMITREG-HGKPVDWWALGCVIYEMV-FGATPFDD-----SNQKILFDRIKNS--PVIFEND-------KNKKVSN--------------NFKDIVNKL | | ..| | |. | ...|. .|..| . . . .. ..|. . . .|| ... . .|..|. .. ECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
|||||||||
Kinase | 26010.AA | S_TK_X | 299-363 | 23 | 3.2e-09 | 37.86 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 299-363 Range on HMM: 1-79/79 Sequence Identity: 23% (21 aa) DKMDWTALSN--QTIAAPFIPAVK----KVSDVSNFDITFTNKDVSDYNNDSTDCSSDDDS-----------------DEYQNFYYDC .. || .| | ..| .||.| .| |.|||| ||..... ..||. |.. .| |.. RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM---------LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF |
|||||||||
Kinase | 26010.AA | Pkinase_Tyr | 111-183 | 35 | 0.00018 | 15.77 | Pfam | 80-156 (270) | Show / Hide |
Range on Protein: 111-183 Range on HMM: 80-156/270 Sequence Identity: 35% (27 aa) NNLFLILDYCSGGDLFNYISK----KNTISEKDAKFYAAQIVLMLEYLHSQNIVYRDLKPENILIEKNGYLKLGDFG |...... |. .||| .| | |. .. || ...|| .|||.|.|.. ||| |.|...|. | .||| NQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG |
|||||||||
Kinase | 26010.AA | Pkinase_Tyr | 40-54 | 40 | 0.184464 | 5.57 | Pfam | 1-15 (270) | Show / Hide |
Range on Protein: 40-54 Range on HMM: 1-15/270 Sequence Identity: 40% (6 aa) FELLNVIGEGKFGTV ... ..||| ||.| ITFGKKLGEGAFGEV |