Gene 19624 (Tetrahymena)
19624
Sequence
Protein domains of 19624.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Ank | 19624.AA | Ank | 320-353 | 41 | 1.8e-08 | 34.78 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 320-353 Range on HMM: 1-33/33 Sequence Identity: 41% (14 aa) SGQTPLMLACMKGNYDVARFLVSHKSVDINSQDL |.|||.|||..|...|...|.. . |.| || DGFTPLHLACRCGHTEVVKMLLQ-HGADVNAQDD |
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Ank | 19624.AA | Ank | 354-377 | 41 | 0.000514 | 18.74 | Pfam | 1-24 (33) | Show / Hide |
Range on Protein: 354-377 Range on HMM: 1-24/33 Sequence Identity: 41% (10 aa) AGNSSLHYACMYGQRKIVEMLLGQ |.. ||.||..|. ..|.|||.. DGFTPLHLACRCGHTEVVKMLLQH |
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Kinase | 19624.AA | AGC | 1134-1390 | 30 | 3.5e-168 | 438.99 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 1134-1390 Range on HMM: 1-395/395 Sequence Identity: 30% (121 aa) YSVYAHLGSGNYGDVYLVEHN------KNKKKYAMKLLDKEK---LIQKNMMKYAIAE------------RNVMQKCN----------SPFIVK-MYHSF . .. ..| | .| ||||... ..| |||| |.|.. ...|||......| ||...||| .||||| ...|| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QTDTH--LIITMDYCP---------GG-DLYTYLL---QKKRFEEELAVKYLSE-------ILLAVEELHY-HDVIYRD-MKPENIVLGSDGHVKLIDFG |...| | . |.|.| || .|...| ...||.|| | |..| |.||.| || ...|.|| .|||||.| .|||.|| ||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG LSRENMGEG---------------------------------------------------VAQSFCG--SAVYLAPEIISKKGHNKSVDWYQ--FGVLAY |. |.|..| ...||| .. |.||||. ..|..||. .|.| | LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY ELMVGQPPFNQLN----------RKELYFNIQ------NKKVEYP----------PYLSFKAKSLISALLNKNPEERLGSGRAD-----AQQIKDHPFF |...|.|||. | ..|.. .|. |.||..| ...| ||.||. ||.|.||.|||.|. | |..||.||.| EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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Kinase | 19624.AA | AktR | 1134-1390 | 49 | 2.5e-163 | 548.89 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 1134-1390 Range on HMM: 1-268/268 Sequence Identity: 49% (132 aa) YSVYAHLGSGNYGDVYLVEHN-KNKKKYAMKLLDKEKLIQKNMMKYAIAERNVMQ-KCNSPFIVKMYHSFQTDTHLIITMDYCPGGDLYTYLLQKKRFEE . ||..||.|..|.||||... .|.|.||||...|.|.|..|.|...| |||.|. .|| |||||....|||...|.. |.|||||.|...| .||.|.| FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE ELAVKYLSEILLAVEELHYH-DVIYRDMKPENIVLGSDGHVKLIDFGLSR-ENM--GEGVAQSFCGSAVYLAPEIISK-KGHNKSVDWYQFGVLAYELMV | | .| ..||||.| ||.| ..||||.|||||.|..|||||..|||||. ..| . .|.||||. .|.|||.| | |||||||||..||.. ||... EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT GQPPFNQLNRKELYFNIQNKK---VEYPPYLSFKAKSLIS-ALLNKNPEERLGSGRADAQQIKDHPFF |.|||.. |.......|..| ..||.|.|...|.|| ||.|||..|||........||.||.| GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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Kinase | 19624.AA | Akt | 1140-1390 | 47 | 1e-124 | 400.6 | In-house | 7-264 (264) | Show / Hide |
Range on Protein: 1140-1390 Range on HMM: 7-264/264 Sequence Identity: 47% (122 aa) LGSGNYGDVYLVEHNKNKKKY-AMKLLDKEKLIQKNMMKYAIAERNVMQKCNSPFIVKMYHSFQTDTHLIITMDYCPGGDLYTYLLQKKRFEEELAVKYL ||.| .| |.||. ....| | ||| | |...|||| .....|||. |.||.||||....|||| ..| . ||||.||.|...| .|.|| |. | | LGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSEDRARFYC SEILLAVEELHYHDVIYRD-MKPENIVLGSDGHVKLIDFGLSREN-MGE-GVAQSFCGSAVYLAPEIISKKGHNKSVDWYQ-FGVLAYELMVGQPPFNQL .|| || | || ...|||| .|||||.. .|||..| ||||..|| . . ....|||.. ||||||....|| |.|||. .|.. ||.| |.||| AEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQ NRKELYFNIQNKKVEYP--PYLSFKAKSLISALLNKNPEERLGSGRADAQQIKDHPFF ...... .|.|..|..| ...| ..|.||| ||||.|..|||.| |||.||.||.| DHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
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Kinase | 19624.AA | RSK-Unclassified | 1134-1390 | 41 | 3.2e-119 | 376.28 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 1134-1390 Range on HMM: 1-283/283 Sequence Identity: 41% (117 aa) YSVYAHLGSGNYGDVYLVEHNKNKKKYAMKLLDKEKLIQKNMMKYAIAERNVMQKCNSPFIVKMYHSFQTDTHLIITMDYCPGGDLYTYLL--QKKRFEE . . .| | | ||||. . .. |||| | |.|.|..| ||.. |.|.| | ||||..|||||| | |.||.|||.. | .|.| | FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE ELAVKYLSEILLAVEELHYHDVIYRDMKPENIVLGSDGHVKLIDFGLSREN---------------------MGEGV-AQSFCGSAVYLAPEIISKKGHN ... |.||. .| | || |.||||.||.|||| .|||.| ||.|| . . .| ..||||. |||||.| || DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT KSVDWYQFGVLAYELMVGQPPFNQLNRKELYFNIQNKKVEYP--PYLSFKAKSLISALLNKNPEERLGSGRADAQQIKDHPFF | |||. |.. ||...| ||. |. |.. || ..| | |.| ....|| .||..|| |||... ||. || |||| KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF |
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Kinase | 19624.AA | RSK | 1137-1390 | 39 | 1.6e-112 | 380.1 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 1137-1390 Range on HMM: 1-278/278 Sequence Identity: 39% (111 aa) YAHLGSGNYGDVYLVEHN---KNKKKYAMKLLDKEKLIQKNM-MKYAIAERNVMQKCN-SPFIVKMYHSFQTDTHLIITMDYCPGGDLYTYLLQKKR--- || | || |.|. .... |||| |.| |..|.. ... .|||... |. .||||. ...|||...| . |.||.||.|.| |...|. LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC FEEELAVKYLSEILLAVEELHYHDVIYRDMKPENIVLGS---DGHVKLIDFGLSRE-NMG-EGVAQSFCGSAVYLAPEIIS----KKGHNKSVDWYQFGV | |. | |..|| |||| || ...|.|| |||||.. . .||.||.|||.... . .. ...||... |.|||.. ..||.|..||. .|| FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV LAYELMVGQPPFNQ---LNRKELYFNIQNKK--VEYP--PYLSFKAKSLISALLNKNPEERLGSGRADAQQIKDHPFF | ||. .|.||| . ||||. .||..| .. | .||| ||.||...| ..|. |||.|. ||..||.||.| LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | 19624.AA | SGK | 1134-1390 | 38 | 1.3e-111 | 346.03 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 1134-1390 Range on HMM: 1-283/283 Sequence Identity: 38% (110 aa) YSVYAHLGSGNYGDVYLVEHNKN------------------KKKYAMKLLDKEKLI-------QKNMMKYAIAER-NVMQKCNSPFIVKMYHSFQTDTHL .| |..| ||.|.| . .|.||||.| |. | .|. |. ||| ..... ..||||. .|||.. | FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL IITMDYCPGGDLYTYLLQKKRFEEELAVKYLSEILLAVEELHYHDVIYRDMKPENIVLGSDGHVKLIDFGLSRENM-GEGVAQSFCGSAVYLAPEIISKK ||| ||.. .| |.| | | | .|| .| |.|| |.|||| |||||.|...||..| ||||. |.. . .|||. |||||.. |. YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ GHNKSVDWYQFGVLAYELMVGQPPFNQLNRKELYFNIQNKKVEYPPYLSFKAKSLISALLNKNPEERLGSGRADAQQIKDHPFF .| ..|||. | . ||.|.| ||| |....| || |.. ||. | .|..|| ||.|.|..|||. ..|. .||.|||| PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGT-KRDFMEIKNHPFF |
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Kinase | 19624.AA | S_TKc | 1134-1390 | 33 | 8.5e-94 | 318.84 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 1134-1390 Range on HMM: 1-231/231 Sequence Identity: 33% (89 aa) YSVYAHLGSGNYGDVYLVEHNKNKKKYAMKLLDKEKLIQKNMMKYAIAERNVMQKCNSPFIVKMYHSFQTDTHLIITMDYCPG--GDLYTYLLQKKR--- | . ..|.| .| ||.. |.| ....|.| .. . .. |.....| . |.|||.| .||. .|| . |.||.| |||..|. ...| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---FEEELAVKYLSEILLAVEELHYHDVIYRDMKPENIVLGSDGHVKLIDFGLSRENMGEGVAQSFCGSAVYLAPEIISKKGHNK-SVDWYQFGVLAYEL | | | .|. .|..|.| .| | .|.|| ||||| | . |.|..||||.|. .|||. |.|||.. |..| ..||. .|.. ||. RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM MVGQPPFNQLNRKELYFNIQNKKVEYPPYLSFKAKSLISALLNKNPEERLGSGRADA--QQIKDHPFF ..|.||| . .... .| | ||..|. .|.|.||.|.. | . . || ||.| LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 19624.AA | RSK | 1134-1390 | 34 | 3.3e-91 | 309.32 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 1134-1390 Range on HMM: 1-271/271 Sequence Identity: 34% (95 aa) YSVYAHLGSGNYGDVYLV---EHNKNKKKYAMKLLDKEKLIQKNMMKYAIAERNVMQKCNSPFIVKMYHSFQTDTHLIITMDYCPGGDLYTYLLQKKRFE | . .| | ...||.. .| ....|||| ..| .. | .. .||... ..||||| . .||. ... . || . |||| . || .| | YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS EELAVKYLSEILLAVEELHYHDVIYRDMKPENIVLGSD----GHVKLIDFGLSRENMGE-GVAQSFCGSAVYLAPEIISKKGHNKSVDWYQFGVLAYELM |. . |..||.||.| || .....|| |||||.. .. ||.|. |||.. . .| | . .||..| |.|||.....|| ...||. |||| || EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEML VGQPPFNQLNRKELYFNIQNKKVEY-------PPYLSFKAKSLISALLNKNPEERLGSGRADAQQIKDHPFF | .|| .|... .||. |. . ..| ||.|....| .|. |||.|. ...||| ||.| TGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF |
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Kinase | 19624.AA | PKA | 1134-1390 | 38 | 3.8e-89 | 302.48 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 1134-1390 Range on HMM: 1-263/263 Sequence Identity: 38% (101 aa) YSVYAHLGSGNYGDVYLVEHNKNKKKYAMKLLDKEKLIQKNMMKYAIAERNVMQKCNSPFIV-KMYHSFQTDTHLIITMDYCPGGDLYTYLLQKKRFEEE . .. ||.| .| |.|. | .... |||| |.|.. .. . . |.|..| ...|||| ||| .||.|..| |.|.|||.. .|| ..|| . FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP LAVKYLS-EILLAVEELHYHDVIYRDMKPENIVLGSDGHVKLIDFGLSRENMGEGVAQSFCGSAVYLAPEIISKK-GHNKSVDWYQFGVLAYELMVGQPP | | .| || | || .. |||| ||||| . ..||.|. ||| . . . . .. || |||||||. | ||.||||| .|.| ||...| || HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP FNQL--NRKELYFNIQNKKVEYPPYLSFKA---KSLISALLNKNPEERLGSGRADAQQIKDHPFF |. . ..| |.| |...|.... .| |.||. ||......|.|. ......||.|..| FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF |
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Kinase | 19624.AA | Ciliate-E2 | 1134-1390 | 24 | 4.6e-85 | 288.91 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 1134-1390 Range on HMM: 1-365/365 Sequence Identity: 24% (92 aa) YSVYAHLGSGNYGDVYLVEHNKNKKK-----------------------YAMKLLDKEKLIQKNMMKYAI----------AERNVMQKCNSPFIVKMYHS | . .|.||.|.||.... |..|. |||| . | ...|...... . |.|.... |.|.|.||| . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FQ--TDTHLIITMDYCPGGDLYTYLLQK-----------KRFEEELAVKYLSEILL---------------AVEELHYHD-VIYRDMKPENIVLGSDGHV || .|... . |.|| ||||. |. .. |.| |. . .. .|| |.|.|| .|.|| |||||.. . FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KLIDFGLSRENMGE--------------------------------GVAQSFCGSAVYLAPEIISKKG---------HNKSVDWYQFGVLAYELMVGQPP |.||||||... . .....||.. |.||||...|. .....|.. .||. ||.. |.|| KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP FNQLNRKELYFNIQNKKVEYPPY------------------LSFKAKSLISA----LLNKNPEERLGSGRADAQQIKDHPFF | . .|...|...|.. .| ..| ||. .|.|.||.|.. ...||..||.| F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT----GWEQILNHPWF |
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Kinase | 19624.AA | p70 | 1134-1390 | 36 | 2.9e-84 | 286.24 | In-house | 1-299 (299) | Show / Hide |
Range on Protein: 1134-1390 Range on HMM: 1-299/299 Sequence Identity: 36% (109 aa) YSVYAHLGSGNYGDVYLVEHNK---NKKKYAMKLLDKEKLI--QKNMMKYA------------------------IAERNVMQKCNSPFIVKMYHSFQTD . || | || |..| . . | |||| | | | . || ||||. ..|||.. .|||. FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN THLIITMDYCPGGDLYTYLLQKKRFEEELAVKYLSEILLAVEELHYHDVIYRDMKPENIVLGSDGHVKLIDFGLSRENMGEGVA-----------QSFCG | .| .|| |.. | . . |. | ||||| .| | || |..|||| ||||. | . |||.| ||||. | . .| .||| GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG SAVYLAPEIISKKGHNKSVDWYQFGVLAYELMVGQPPFNQLNRKELYFNIQNKK--VEYPPYLSFKAKSLISALLNKNPEERLGSGRADAQQIKDHPFF | ||||....|||. |||. |.| | ..|.||| |||. |. | .. ||||. .. || .|| ..| .|.|.| ||..|. |||| TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF |
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Kinase | 19624.AA | Pkinase | 1134-1390 | 26 | 2.8e-83 | 287.79 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 1134-1390 Range on HMM: 1-293/293 Sequence Identity: 26% (81 aa) YSVYAHLGSGNYGDVYLVEHNKNKKKYAMKLLDKEKLIQKNMMKYAIA--ERNVMQKCNSPFIVKMYHSFQTDTHLIITMDYCPGG----DLYTYLL--Q | . .|||..| ||. | .. |..|.| ..|. . ... .... | .|...|.|.||..|..|....|. . |.||.|| ||..|. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR KKRF--EEELAVKYLSEILLAVEELHYHDVIYRDMKPENIVLGSDGHV----KLIDFGLSRE--NMGEGVAQSFCGSAVYLAPEIIS-KKGHNKSVDWYQ ...| .|. . .|. .|| ..| .| . .|.||.||||| . ..||. |..||||.. . . ...|||. |.|||.| ... ..||.. HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS FGVLAYELMVGQPPFNQL------NRKELYFNIQNKKVEYPPYLS---------------------FKAKSLISALLNKNPEERLGSGRADAQQIKDHPF .|.. ||.. |.||| . . ......| ...... . . .|..|. .|.|.|..|.. |.||. ||. CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPW F | F |
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Kinase | 19624.AA | TyrKc | 1134-1384 | 21 | 1e-11 | -33.11 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 1134-1384 Range on HMM: 1-280/280 Sequence Identity: 21% (62 aa) YSVYAHLGSGNYGDVYLVEHNKNKKKYAMKLLDKEKLIQKNMMKYAIAERNVMQKC--NSPFIVKMYHSFQTD-------THLIITMDYCPGGDLYTYLL . ||.|..| ||. . . . | | | ... .. .|. | ..| | . | ||..| .. | | | |.|.||| || ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMR----EARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR QKKR-FEEELAVKYLSEILLAVEELHYHDVIYRDMKPENIVLGSDGHVKLIDFGLSRENMGE------GVAQSF----CGSAV----YLAPEIISKKGHN ... . . ... | | || . .| || |. .|....|| ||||||. . . . .| .. .||| | .. . KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT KSVDWYQFGVLAYELM-VGQPPFNQ-----LNRKELYFNIQNKKVEYPPYL---------SFKAKSLISALLNKNPEERLGSGRADAQQI | . |||. .|.. ||.| .. .|.. .... . .| . . .... . .||.| ... TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF |
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Kinase | 19624.AA | Pkinase_Tyr | 1134-1228 | 26 | 0.001658 | 12.5 | Pfam | 1-106 (270) | Show / Hide |
Range on Protein: 1134-1228 Range on HMM: 1-106/270 Sequence Identity: 26% (28 aa) YSVYAHLGSGNYGDVYLVEHN----KNKKKYAMKLLDKEKLIQKN-MMKYAIAERNVMQKC-NSPFIVKMYHSFQ-TDTH--LIITMDYCPGGDLYTYLL . ||.|..|.||. . . ..| . | | | ||. ... ... ..| ..| . . | ||..| . . ..| | |.|.|||..|| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR QK---KR .. |. KHREDKQ |
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Kinase | 19624.AA | Pkinase_Tyr | 1262-1280 | 42 | 0.243765 | 5.16 | Pfam | 141-159 (270) | Show / Hide |
Range on Protein: 1262-1280 Range on HMM: 141-159/270 Sequence Identity: 42% (8 aa) NIVLGSDGHVKLIDFGLSR |. ......|| ||||.| NCLVTENNVVKICDFGLAR |