Gene 1697 (Tetrahymena)

1697

Species: Tetrahymena
Alias: 246.m00026, 1697, 786, TTHERM_01126380, PreTt01697
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: AGC
Family: AktR

Sequence

Name Sequence Type Origin Length Description Download
1697.AA Protein None 449 None Fasta, JSON
1697.kin_dom Protein Kinase Domain None 259 None Fasta, JSON
1697.NA RNA None 1350 None Fasta, JSON

Protein domain

Protein domains of 1697.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 1697.AA AGC 104-362 31 9.1e-175 456.42 In-house 1-395 (395) Show / Hide 
Range on Protein: 104-362
Range on HMM: 1-395/395
Sequence Identity: 31% (124 aa)

FVIDRPLGKGAFGQVYLVTKK------DSQRKYAMKTIKKID-MVKLQ--LIEATILE------------KTILLKSS----------HPFIVQ-LKYCI
| . ...|||.||.|||| ||      |... |||| .|| . .|...   .| |. |            . || | .          |||||. |.|. 
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTEKK--IYLIMEYIQ---------GG-ELFTLLK---HCGQFTEKVAKFIIAE-------IILGIQYLHETLKIIYRD-IKPENILLTKSGHIKISDFG
|....  .|..|||..         || |||. |.   ..| |.|..|.|..||       |.|...|||. ..||.|| .|||||||.. ||||..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKEFQNKD--------------------------------------------------EKTYTFAG--TPEYLAPEIVLNKGHNKNVDLWG--IGVFLY
|.||. |..                                                  ..|.|| |  ||||.||||.    ..| .| |.   |...|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELVAGYPPFQDKNRN--------YDKISKQII------MNRPTYP----------ENFSPNLKDLIKKLLNSDPQMRLGANS-------FTDLKEHPFF
|...|||||...|..         ... ..|.      ......|          ..|||..||||||||. ||  |||..        . ..|.||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 1697.AA AktR 104-362 51 5.6e-166 557.71 In-house 1-268 (268) Show / Hide 
Range on Protein: 104-362
Range on HMM: 1-268/268
Sequence Identity: 51% (137 aa)

FVIDRPLGKGAFGQVYLVTKK-DSQRKYAMKTIKKIDMVKLQLIEATILEKTILL-KSSHPFIVQLKYCIQTEKKIYLIMEYIQGGELFTLLKHCGQFTE
|.. ..|||||||.||||.|| |.|..|||| ||| ..........||.|..|.  ...|||||.|.||.||..|...||||..|||||. ||....|.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

KVAKFIIAEIILGIQYLHETLKIIYRDIKPENILLTKSGHIKISDFGLSK-EFQN-KDEKTYTFAGTPEYLAPEIVLN-KGHNKNVDLWGIGVFLYELVA
..|.|..|.|.|...|||....|||||.||||||| . ||.||.|||||| .|.. .|||.|.| |||||.|||.... |||||.||.| .|.|.||.|.
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GYPPFQDKNRNYDKISKQIIM-NRPTYPENFSPNLKDLIK-KLLNSDPQMRLG--ANSFTDLKEHPFF
|.|||..||.|.. ....|.. |...||..||...||||. |||. .|..|||  .|.....|.||.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 1697.AA Akt 104-362 47 2.8e-120 386.22 In-house 1-264 (264) Show / Hide 
Range on Protein: 104-362
Range on HMM: 1-264/264
Sequence Identity: 47% (127 aa)

FVIDRPLGKGAFGQVYLVTKKDSQRKY-AMKTIKKIDMVKLQLIEATILEKTILLKSSHPFIVQLKYCIQTEKKIYLIMEYIQGGELFTLLKHCGQFTEK
| . . ||||.||.|.|| |||.|. | ||| .||   ..   .| |. |. || .  |||||.|.|  ||..|.|..|.|..|||||..|.... |.|.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

VAKFIIAEIILGIQYLHETLKIIYRD-IKPENILLTKSGHIKISDFGLSKEF-QNKDEKTYTFAGTPEYLAPEIVLNKGHNKNVDLWG-IGVFLYELVAG
 |.| .|||||.|..||.   |||||  ||||||. | |||.. ||||.||     ..||.|| |||||||||| ...|| | || || .|...||.  |
RARFYCAEIILAIEHLHS-KNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG

YPPFQDKNRNYDKISKQIIMNRPTYP--ENFSPNLKDLIKKLLNSDPQMRLG--ANSFTDLKEHPFF
 ||| ....  ..  |.| ..   .|  ...||. ||||..||| || .|||   |   ..|.||.|
RPPFYNQDH--HQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 1697.AA Ciliate-E2b 104-362 35 1.8e-108 330.62 In-house 1-272 (272) Show / Hide 
Range on Protein: 104-362
Range on HMM: 1-272/272
Sequence Identity: 35% (96 aa)

FVIDRPLGKGAFGQVYLVTK-KDSQRKYAMKTIKKIDMVKLQLIEATILEKTILLKSSHPFIVQLKYCIQTEKKIYLIMEYIQGGELFTLLKHCG--QFT
...   ||.|.|| |||| . |.... |||| |.|   ..  .    . || .|.|  ||||.....  ......|..||...|.|||...   |   . 
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLS

EKVAKFIIAEIILGIQYLHETLKIIYRDIKPENILLTKSGHIKISDFGLSKEFQNKDE---KTYTFAGTPEYLAPEIVL-----NKGHNKNVDLWGIGVF
.....|.||.|.|...||| ...|||||||||||.... |..|. |.|..| .. | |   .|.|  |||.|.||||.      .|| . .||.| .|..
TYDSQFYIASICLCLEYLH-NQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGIC

LYELVAGYPPFQDKNRNYDKISKQIIMN--RPTYPENFSPNLK--DLIKKLLNSDPQMRLGANSFTDLKEHPFF
|||.  ||.|.  . ..   | ..|| .  .  .|  ..  ..  .|. ..|.. |..|||  |.  || ||.|
LYEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQFPSYCKDKMADKKLMLQCLQKMPEVRLGG-SYSWLKSHPWF
Kinase 1697.AA PKA 104-362 45 2.5e-108 366.18 In-house 1-263 (263) Show / Hide 
Range on Protein: 104-362
Range on HMM: 1-263/263
Sequence Identity: 45% (121 aa)

FVIDRPLGKGAFGQVYLVTKKDSQRKYAMKTIKKIDMVKLQLIEATILEKTILLKSSHPFIV-QLKYCIQTEKKIYLIMEYIQGGELFTLLKHCGQFTEK
| | . ||.| || |.|. .|.| . ||||..|| . |.|  .| .. ||.||.  .||||| ....  |.....|..|||..|||.|. | . | |...
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

VAKFIIA-EIILGIQYLHETLKIIYRDIKPENILLTKSGHIKISDFGLSKEFQNKDEKTYTFAGTPEYLAPEIVLNK-GHNKNVDLWGIGVFLYELVAGY
.|||..| .|.| ..||| .. ||||| ||||||. | ||||| ||| .|. ..    |.|  ||||||||||...| ||.| || |  |.  ||..|||
HAKFYAASQIVLALEYLH-SQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD---RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGY

PPFQDKNRNYDKISKQIIMNRPTYPENFSPNL---KDLIKKLLNSDPQMRLGANSF--TDLKEHPFF
||| |.||.  .| . |.  .  .|..|....   ||||||||. |.  |.|  ..   | |.|..|
PPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 1697.AA RSK 108-362 42 1.7e-107 363.4 In-house 2-278 (278) Show / Hide 
Range on Protein: 108-362
Range on HMM: 2-278/278
Sequence Identity: 42% (119 aa)

RPLGKGAFGQVYLVTKK---DSQRKYAMKTIKKIDMVKLQL-IEATILEKTILLKSS-HPFIVQLKYCIQTEKKIYLIMEYIQGGELFTLLKHCGQ---F
. ||.|..| |.|. |.   |... |||| .||  .|. |  .. |  | .||. .  |||||.|.|  |||.|.||||||. |||||| |.. ..   |
KVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCF

TEKVAKFIIAEIILGIQYLHETLKIIYRDIKPENILLTK---SGHIKISDFGLSKEFQNK-DEKTYTFAGTPEYLAPEIVL----NKGHNKNVDLWGIGV
.|. |.|..|||.| ...||. ..||.||.||||||..    .||||..|||..|.| ..  ..|.|| .| ||.|||..     ..||.|..|.|  ||
SEDEACFYMAEIVLAVEHLHQ-QGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

FLYELVAGYPPFQDKNR-NYDKISKQIIMNR--PTYP--ENFSPNLKDLIKKLLNSDPQMRLG--ANSFTDLKEHPFF
 .||. .|.||||  |. | ..|.|.|  ..  .| |  .. |.. ||||.|.|  ||..|||   .   ..|.||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 1697.AA SGK 104-362 39 5.70000000001e-107 331.45 In-house 1-283 (283) Show / Hide 
Range on Protein: 104-362
Range on HMM: 1-283/283
Sequence Identity: 39% (115 aa)

FVIDRPLGKGAFGQVYLVTKKDS------------------QRKYAMKTIKKIDMV-------KLQLIEATILEK-TILLKSSHPFIVQLKYCIQTEKKI
| .   .||| || ||.| .||                   . .|||| ..|   .       |  .   .  |. .|| . .|||||.|.|  ||..| 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLIMEYIQGGELFTLLKHCGQFTEKVAKFIIAEIILGIQYLHETLKIIYRDIKPENILLTKSGHIKISDFGLSKEFQNKDEKTYTFAGTPEYLAPEIVLN
|. |.|..|||.|  |.  . | | .|.|  |||.. . |||. ..||||| |||||||   ||... ||||.||   . ..| ||.|||||||||. . 
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHS-QDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRK

KGHNKNVDLWGIGVFLYELVAGYPPFQDKNRN--YDKISKQIIMNRPTYPENFSPNLKDLIKKLLNSDPQMRLGAN-SFTDLKEHPFF
..| . || | .| .|||.  | ||| ..|..  ||.| .| .      | ..|.  .|||. ||. ||. |||..  | . |.||||
QPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQ----IPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 1697.AA S_TKc 104-362 37 2e-106 360.77 SMART 1-231 (231) Show / Hide 
Range on Protein: 104-362
Range on HMM: 1-231/231
Sequence Identity: 37% (102 aa)

FVIDRPLGKGAFGQVYLVTKKDSQRKYAMKTIKKIDMVKLQLIEATILEKTILLKSSHPFIVQLKYCIQTEKKIYLIMEYIQG--GELFTLLKHCGQ---
. | |..||||||.||....|...|..|.| ||          | .. |  || |  ||.||.|....|. ...|..|||. |  |.||...|..|    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FTEKVAKFIIAEIILGIQYLHETLKIIYRDIKPENILLTKSGHIKISDFGLSKEFQNKDEKTYTFAGTPEYLAPEIVLNKGHNK-NVDLWGIGVFLY
   |.| .|.|....|.....|.|.  .||.||.|||||||..  ||||.||||....       .|| |||.|.|||..   |..|  .| | .|. ||
RFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELVAGYPPFQDKNRNYDKISKQIIMNRPTYPENFSPNLKDLIKKLLNSDPQMRLGANSFTD----LKEHPFF
|...|||||.    ..... |.|           || .||.|.|.|. ||. |..|          | ||.|
EMLCGYPPFP----QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 1697.AA Ciliate-E2-Unclassified 104-362 31 7.1e-97 328.15 In-house 1-352 (352) Show / Hide 
Range on Protein: 104-362
Range on HMM: 1-352/352
Sequence Identity: 31% (110 aa)

FVIDRPLGKGAFGQVYLVTKKDSQRKYAMKTIKKIDMVKLQLIEA---------TILEKT-------------ILLKSSHPFIVQLKYCIQTEKKIYLIM
. | . .|.|.||.||.. .|. . .||||..||| ..| ..|.          .. .|              ||| . ||||| . || |....||..|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYIQGGELFTLLKHCGQ-----------------FTEKVAK-----FIIAEIILGIQYLHETLKIIYRDIKPENILLTKSG---HIKISDFGLSKEFQN-
||..||.|.  .|....                 |||. ||     |..|.|..|..|||. ..||.|||||||||....|   .|||.|||.||. |. 
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

--------------KDEKTYTFAGTPEYL----APEIVLNKGHN----KNVDLWGIGVFLYELVAGYPPFQDKNRNY-------------DKISKQIIMN
              |.....||.|||.|.    |||.  .....    . .| |. || |||.. ||.||.|.|..              .|. .|.|..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

R----PTYPE-----NFSPNLKDLIKKLLNSDPQMRLGAN-SFTDLKEHPFF
.    | .|.     . ||. ||.|..|| .... ... . .| ....||.|
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 1697.AA Ciliate-E2 104-362 26 1.4e-94 320.52 In-house 1-365 (365) Show / Hide 
Range on Protein: 104-362
Range on HMM: 1-365/365
Sequence Identity: 26% (101 aa)

FVIDRPLGKGAFGQVYLVTK-----------------------KDSQRKYAMKTIKKIDMVKLQLIEATI----------LEKTILLKSSHPFIVQLKYC
. . . .|.|.||.||....                       |. . .||||..|| .   .  ..  .           || || . .||.|.....|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IQ--TEKKIYLIMEYIQGGELFTLLK-------------------HCGQFTEKVAK-------FIIAEIILGIQYLHETLKIIYRDIKPENILLTKSGHI
 |  ....|||.|||.|||.|| ..|                   ...........       |.||.|||...|||.  .||.|||||||||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KISDFGLSKEFQNK-------------------------------DEKTYTFAGTPEYLAPEIVLNKG---------HNKNVDLWGIGVFLYELVAGYPP
||.||||||.....                               .. ..|..|||.|.||||. .|.         ... .|.| .|| |||.. |.||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FQDKNRNYDKISKQIIMN-RPTYP------------------ENFSPNLKDLIKK----LLNSDPQMRLGANSFTDLKEHPFF
|            |.|..    .|                  .. |.. ||||||    .|. ||. |..  .. ....||.|
F-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF
Kinase 1697.AA Pkinase 104-362 31 6.8e-91 313.06 Pfam 1-293 (293) Show / Hide 
Range on Protein: 104-362
Range on HMM: 1-293/293
Sequence Identity: 31% (93 aa)

FVIDRPLGKGAFGQVYLVTKKDSQRKYAMKTIKKIDMVKLQLIEATI-LEKTILLKSSHPFIVQLKYCIQTEKKIYLIMEYIQGG----ELFTLLK--HC
..| |..|.|.||.||. ..|......|.|.||| .  . ......   |  |... .||.||.|... .....||..||| .||    .||....    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GQF--TEKVAKFIIAEIILGIQYLHETLKIIYRDIKPENILLTKSGHI----KISDFGLSKEF-QNKDEKTYTFAGTPEYLAPEIVL-NKGHNKNVDLWG
| |  .|...||.. .|. |..|.|.  .||.||.||||||. . |||    ||.||||.| |   ... ..||.|||.|.|||... .... . || |.
GCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

IGVFLYELVAGYPPFQDK----NRNYDKISKQIIMNRPTYPENFS---------------------PNLKDLIKKLLNSDPQMRLGANSFTDLKEHPFF
.|. |||.. |.|||...    |.. ... ..| . .. ...  .                     ...||.||..|. ||. |..   ......||.|
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF
Kinase 1697.AA MAST 104-251 43 1.8e-61 196.76 In-house 1-147 (334) Show / Hide 
Range on Protein: 104-251
Range on HMM: 1-147/334
Sequence Identity: 43% (64 aa)

FVIDRPLGKGAFGQVYLVTKKDSQRKYAMKTIKKIDMVKLQLIEATILEKTILLKSSHPFIVQLKYCIQTEKKIYLIMEYIQGGELFTLLKHCGQFTEKV
| . .|..|||.|.|||| .|.. . .|||.||| || .   ..  . |..||  .. ||.| . |. ||.......||| .|| ...||.. | | |  
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

AKFIIAEIILGIQYLHETLKIIYRDIKPENILLTKSGHIKISDFGLSK
||..|||..|...|||.   |. ||.||.|.|....||||. ||||||
AKMYIAETVLCLEYLHSH-GIVHRDLKPDNMLIDSNGHIKLTDFGLSK
Kinase 1697.AA MAST 265-362 41 1e-37 118.95 In-house 226-334 (334) Show / Hide 
Range on Protein: 265-362
Range on HMM: 226-334/334
Sequence Identity: 41% (46 aa)

GTPEYLAPEIVLNKG-HNKNVDLWGIGVFLYELVAGYPPFQDKNRNYDKISKQIIMNR---PTYPEN--------FSPNLKDLIKKLLNSDPQMRLGAN-
|||.|.|||. |..| |.| || |  |. .||. .|.|||.|....  .|  .|.  .     .||         .||  .|||.|||. ||  ||||| 
GTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPE--EIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANN

SFTDLKEHPFF
  .. |.||||
GADEVKQHPFF
Kinase 1697.AA TyrKc 104-362 24 2.5e-16 41.44 SMART 1-280 (280) Show / Hide 
Range on Protein: 104-362
Range on HMM: 1-280/280
Sequence Identity: 24% (71 aa)

FVIDRPLGKGAFGQVYLVTKKDSQRKYAMKTIKKIDMVKLQLIEATILEKTILLKS--SHPFIVQLKYCIQTE-------KKIYLIMEYIQGGELFTLLK
 . .. || ||||.||. | |   .. | |..|.        .|. . |  |. |   .|| ||.|  .. ..       . ....|||  .| |   |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

HCGQ-FTEKVAKFIIAEIILGIQYLHETLKIIYRDIKPENILLTKSGHIKISDFGLSKEFQNKD-----EKTYTFAG--TPE------YLAPEIVLNKGH
 ..  .. |    .   |  | .|||.  ..| ||.   |.|... ...||||||||..  ..|     ...|. ..            .|||    .  
KHRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

NKNVDLWGIGVFLYELVA-GYPPFQD----KNRNYDKISKQIIMNRPTYPEN--------FSPNLKDLIKKLLNSDPQMRLGANSFTDLKEHPFF
.   | |  || ..|.   | .|  .    .  |.. | .    .|.  |.|         .. . ...|.  . || .|    .|...  | .|
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP---TFSEI--HECF
Kinase 1697.AA Pkinase_Tyr 104-189 30 1.1e-11 40.16 Pfam 1-94 (270) Show / Hide 
Range on Protein: 104-189
Range on HMM: 1-94/270
Sequence Identity: 30% (29 aa)

FVIDRPLGKGAFGQVYLVTKK----DSQRKYAMKTIKKIDMVK-LQLIEATILEKTILLKS-SHPFIVQLKYCIQ-TEKK--IYLIMEYIQGGEL
 .... ||.||||.||. | |    . . . | |..|   | . . ..|. . |  |. .  .|| ||.|  ..   ..   ||..||| ..| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL
Kinase 1697.AA Pkinase_Tyr 233-258 42 1.5e-05 19.44 Pfam 141-166 (270) Show / Hide 
Range on Protein: 233-258
Range on HMM: 141-166/270
Sequence Identity: 42% (11 aa)

NILLTKSGHIKISDFGLSKEFQNKDE
|.|.|.....||.||||..  .|.|.
NCLVTENNVVKICDFGLARDIYNDDY