Gene 19784 (Tetrahymena)
19784
Sequence
Protein domains of 19784.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 19784.AA | Akt | 76-328 | 59 | 4.6e-193 | 622.6 | In-house | 4-264 (264) | Show / Hide |
Range on Protein: 76-328 Range on HMM: 4-264/264 Sequence Identity: 59% (156 aa) IHVLGKGSFGKVVLVEKKDTKELY-AMKILKKDYIQYTNQKFNTQQERDILVKMNSPFIVKLHYAFQTADKLYIVMDFMIGGELFYHLRRSPIFTEEKAA ..||||||||||.||.||||...| |||.||||||.. ||. .|..|| ||...|.||||.|||.|||.||||.|||.. ||||||||.| ..|.|..| LKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSEDRAR YYSAEIILGIEALHSNNIIYRD-LKPENILIDHKGHLRLADFGLSKKG-VKDHERTNSLCGTPEYLAPEILLNNGHTKMVDWWS-LGAIIYEMLTGAPPF .| |||||.||.|||.|||||| |||||||.|..||..|.||||.|.. .|||..|...||||||||||||..|||||.||||. ||...|||..|.||| FYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPF YNKNQKQMFKDRFLKPIEMK--EWFSPAAKSLLSGLLNINPELRLG--FKGIQEIKEHEFY ||....|||| . .|.... .|.||..|.|.||||| .|..||| ....||||.|... YNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
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Kinase | 19784.AA | AGC | 74-328 | 35 | 1.4e-183 | 479.71 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 74-328 Range on HMM: 1-395/395 Sequence Identity: 35% (141 aa) FGIH-VLGKGSFGKVVLVEKK------DTKELYAMKILKKDY-IQYTN--QKFNTQQE------------RDILVKMN----------SPFIVK-LHYAF | .. |.|||||||| ||.|| ||...||||.|||.. |. .. . .|. | |.||.|.| .||||| |||.| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QTADK--LYIVMDFMI---------GG-ELFYHLR---RSPIFTEEKAAYYSAE-------IILGIEALHS-NNIIYRD-LKPENILIDHKGHLRLADFG |. |. ||.||..|. || |||.||. .. .|.|| | .| || |.|..| ||| ..||.|| |||||||.|..||..|.||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG LSKKGVKDH--------------------------------------------------ERTNSLCG--TPEYLAPEILLNNGHTKMVDWWS--LGAIIY |.|.|..|. .||...|| ||||.||||| ..| .|||| ||...| LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY EMLTGAPPFYNKN----------QKQMFKDRF------LKPIEMK----------EWFSPAAKSLLSGLLNINPELRLGFK-------GIQEIKEHEFY ||||| ||||..| ...||. ..... .|||| ||.|...||. .|| ||| . |..|||.|.. EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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Kinase | 19784.AA | SGK | 76-328 | 46 | 6.5e-150 | 466.44 | In-house | 4-283 (283) | Show / Hide |
Range on Protein: 76-328 Range on HMM: 4-283/283 Sequence Identity: 46% (131 aa) IHVLGKGSFGKVVLVEKKDT------------------KELYAMKILKKDYIQ-------YTNQKFNTQQER-DILVKMNSPFIVKLHYAFQTADKLYIV ..|.|||||||| .|..||. . .||||.|.|. | .. ... || .||..|..||||.|||||||..||| | LKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKLYFV MDFMIGGELFYHLRRSPIFTEEKAAYYSAEIILGIEALHSNNIIYRDLKPENILIDHKGHLRLADFGLSKKGVKDHERTNSLCGTPEYLAPEILLNNGHT ||.. |||.||||.| .| | .| | |||.. .| ||| .|||||||||||| ||.||..| ||||.| |.|. . | . ||||||||||.|. .| MDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQPHD KMVDWWSLGAIIYEMLTGAPPFYNKNQKQMFKDRFLKPIEMKEWFSPAAKSLLSGLLNINPELRLGFK-GIQEIKEHEFY . ||||.||.. |||..|.||||..| .||. . .|. .. .|..|..|. |||. .|. ||| | . |||.| | RTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF |
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Kinase | 19784.AA | AktR | 76-328 | 50 | 1.5e-133 | 450.01 | In-house | 4-268 (268) | Show / Hide |
Range on Protein: 76-328 Range on HMM: 4-268/268 Sequence Identity: 50% (133 aa) IHVLGKGSFGKVVLVEKK-DTKELYAMKILKKDYIQYTNQKFNTQQERDILV-KMNSPFIVKLHYAFQTADKLYIVMDFMIGGELFYHLRRSPIFTEEKA . .|||| ||||.||.|| |....||||..|| |. ||. |..||.|. ..| ||||||||.||| .||...|... |||||.||... |.||.| YKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSEEQA AYYSAEIILGIEALHSN-NIIYRDLKPENILIDHKGHLRLADFGLSK-KGVK-DHERTNSLCGTPEYLAPEILLN-NGHTKMVDWWSLGAIIYEMLTGAP |.|.|.|..| ||.. |||||||||||||.| ||....|||||| ... . |...|.||||||.|||.... ||.|.||||..|. ||||.|| | RFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCP PFYNKNQKQMFKDRFLKP-IEMKEW--FSPAAKSLLS-GLLNINPELRLG--FKGIQEIKEHEFY |||.|||.|||. |. .. .. ||...|.|. .||. ||. ||| .|..|||.| . PFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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Kinase | 19784.AA | RSK | 76-328 | 43 | 1.8e-116 | 393.21 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 76-328 Range on HMM: 1-278/278 Sequence Identity: 43% (121 aa) IHVLGKGSFGKVVLVEKK---DTKELYAMKILKKDYIQYTNQ-KFNTQQERDILVKMN-SPFIVKLHYAFQTADKLYIVMDFMIGGELFYHLRRSPI--- . |||.|..||| |. |. ||. .||||.||| | .. | .||.|| . .||||.||||||| .|||..|... |||||.||.. . LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC FTEEKAAYYSAEIILGIEALHSNNIIYRDLKPENILIDH---KGHLRLADFGLSKKGVKD-HERTNSLCGTPEYLAPEILL----NNGHTKMVDWWSLGA |.|. |..| |||.| .| ||. ||.||||||||| |. ||..| |||..|... | ..|.. |.| ||.|||.| ..||.| .||||||. FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV IIYEMLTGAPPFYN---KNQKQMFKDRFLKP--IEMK--EWFSPAAKSLLSGLLNINPELRLG--FKGIQEIKEHEFY ..||||||.|||.. .|.|. .| . .|. . |..||.|....| .|. ||| ....|||.|.. LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | 19784.AA | RSK | 74-328 | 40 | 4.6e-110 | 371.95 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 74-328 Range on HMM: 1-271/271 Sequence Identity: 40% (110 aa) FGIH-VLGKGSFGKVVLVEKK---DTKELYAMKILKKDYIQYTNQKFNTQQERDILVKMNSPFIVKLHYAFQTADKLYIVMDFMIGGELFYHLRRSPIFT . .| ..|.|||.|| .. |. ||. .|||||.||. . . . . ||.|| ..||||||||.||.. |.|..|||| ||.|| .| . . |. YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS EEKAAYYSAEIILGIEALHSNNIIYRDLKPENILIDHK----GHLRLADFGLSKKGVKDHER-TNSLCGTPEYLAPEILLNNGHTKMVDWWSLGAIIYEM |.... | ||| | | ||| |..|||||||||.| . ||....|||..|. ..|.. . . |.| .|.|||.| ||.. .||||.|.. ||| EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQ-LRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEM LTGAPPFYNKNQKQMFKDRFLKPIEM-------KEWFSPAAKSLLSGLLNINPELRLGF--KGIQEIKEHEFY |||..||.||. . .. . | .. |. ||.||...| ..|. ||| |...||.| .. LTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF |
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Kinase | 19784.AA | RSK-Unclassified | 76-328 | 39 | 2.3e-106 | 335.18 | In-house | 4-283 (283) | Show / Hide |
Range on Protein: 76-328 Range on HMM: 4-283/283 Sequence Identity: 39% (111 aa) IHVLGKGSFGKVVLVEKKDTKELYAMKILKKDYIQYTNQKFNTQQERDILVKMNSPFIVKLHYAFQTADKLYIVMDFMIGGELFYHLR--RSPIFTEEKA . .|.|.|||| ||.||||. .||||.|.|. . | |..|. | ||||.| ..||| |.|| .|.. ||..| || .. |.|... HRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCEDDV AYYSAEIILGIEALHSNNIIYRDLKPENILIDHKGHLRLADFGLSKKG-------VK--------------DHERTNSLCGTPEYLAPEILLNNGHTKMV .| .|... | || .|||||||.||. .. || .| ||.||... .| . |||| ||| ||||||.. .|||| | RFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHTKAV DWWSLGAIIYEMLTGAPPFYNKNQKQMFKDRFLKPIEMK--EWFSPAAKSLLSGLLNINPELRLGFK-G-IQEIKEHEFY ||| || ..|||| | ||.| |. .|. ... . . | ...|. ||. || ||| | | ..|| | |. DWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF |
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Kinase | 19784.AA | PKA | 73-328 | 45 | 5.8e-106 | 358.33 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 73-328 Range on HMM: 1-263/263 Sequence Identity: 45% (122 aa) TFGIHVLGKGSFGKVVLVEKKDTKELYAMKILKKDYIQYTNQKFNTQQERDILVKMNSPFIV-KLHYAFQTADKLYIVMDFMIGGELFYHLRRSPIFTEE | .||.||||.| |. .|.... ||||.|||..| ..|. . |. || ...|||| |. . ||....|| ||.. |||.|..||.| |.. FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP KAAYYSA-EIILGIEALHSNNIIYRDLKPENILIDHKGHLRLADFGLSKKGVKDHERTNSLCGTPEYLAPEILLNN-GHTKMVDWWSLGAIIYEMLTGAP | | | .|.| .| ||| ||||||||||||||| .||. ..||| .|| |.| || .||||||||||||... || | ||||.|| .|||||.| | HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKK-VDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYP PFYNK--NQKQMFKDRFLKPIEMKEWFSPAA---KSLLSGLLNINPELRLG-FK-GIQEIKEHEFY |||.. .. |... |.. . |...| |.|.. ||. ... |.| .| |.. ||.|.. PFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF |
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Kinase | 19784.AA | S_TKc | 73-328 | 36 | 2e-103 | 350.85 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 73-328 Range on HMM: 1-231/231 Sequence Identity: 36% (97 aa) TFGIHVLGKGSFGKVVLVEKKDTKELYAMKILKKDYIQYTNQKFNTQQERDILVKMNSPFIVKLHYAFQTADKLYIVMDFMIG--GELFYHLRRSPI--- . ..|||.|||| .. .|.|....|.||.| ....|..|| | . |.||||...||. |.||.||... | |.|| .... . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---FTEEKAAYYSAEIILGIEALHSNNIIYRDLKPENILIDHKGHLRLADFGLSKKGVKDHERTNSLCGTPEYLAPEILLNNGHTK-MVDWWSLGAIIYE |.| |..| ..|....| .||..||.|||||||||.|. |. ..||||... ...||||.|.|||.| |..| .||||.| |.|| RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE MLTGAPPFYNKNQKQMFKDRFLKPIEMKEWFSPAAKSLLSGLLNINPELRLGFKGIQE----IKEHEFY ||.| |||. ....||| || ||......|. .|| |.. . . || |.. MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 19784.AA | PKC | 76-328 | 42 | 7.79999999999e-101 | 327.58 | In-house | 4-262 (262) | Show / Hide |
Range on Protein: 76-328 Range on HMM: 4-262/262 Sequence Identity: 42% (111 aa) IHVLGKGSFGKVVLVEKKDTKELYAMKILKKDYIQYTNQKFNTQQERDILVK-MNSPFIVKLHYAFQTADKLYIVMDFMIGGELFYHLRRSPIFTEEKAA . ||||||||||.|.|.|.|.|.||.|.|||| | . |. |. .| . || ..|| ||| |.|. || . || | .| .. | ||.|. LKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEEHAR YYSAEIILGIEALHSNNIIYRDLKPENILIDHKGHLRLADFGLSKKGVKDHERTNSLCGTPEYLAPEILLNNGHTKMVDWWSLGAIIYEMLTGAPPFYNK |.||||.. ||...||||||| .|.|.|| || ..||||..| .. . ..|.. ||||.|.||||| .| ||||..| |||. | .|| . FYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPFHGE NQKQMFKDRFLKPIEMKEWFSPAAKSLLSGLLNINPELRLGF-----KGIQEIKEHEFY . ..|. . . |.| |.|...|... ||| ||| .| |.|.|| |. DEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF |
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Kinase | 19784.AA | p70 | 76-328 | 37 | 8.7e-98 | 331.17 | In-house | 4-299 (299) | Show / Hide |
Range on Protein: 76-328 Range on HMM: 4-299/299 Sequence Identity: 37% (112 aa) IHVLGKGSFGKVVLVEKKD---TKELYAMKILKKDYIQYTNQKFNTQQ--------------------------ERDILVKMNSPFIVKLHYAFQTADKL . ||||| .||| .| | | .|||| |.| | . || || ..|||..||||||| || LKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTNGKL YIVMDFMIGGELFYHLRRSPIFTEEKAAYYSAEIILGIEALHSNNIIYRDLKPENILIDHKGHLRLADFGLSKKGVKDHER----------TNSLCGTPE | . ... |||||.|| | |. |. | .| .|||. .| ||. ||||||||||.. ...||. | ||||.|. ..| . | ..|||.| YLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCGTIE YLAPEILLNNGHTKMVDWWSLGAIIYEMLTGAPPFYNKNQKQMFKDRFLKP--IEMKEWFSPAAKSLLSGLLNINPELRLG--FKGIQEIKEHEFY | |||||. || . |||||||. .| ||||.||| | |. . ... .. .. |. || .| .|.| ...|.||.|. YMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF |
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Kinase | 19784.AA | Pkinase | 76-328 | 30 | 2.4e-90 | 311.23 | Pfam | 4-293 (293) | Show / Hide |
Range on Protein: 76-328 Range on HMM: 4-293/293 Sequence Identity: 30% (90 aa) IHVLGKGSFGKVVLVEKKDTKELYAMKILKKDYIQYTNQKFNTQ-QERDILVKMNSPFIVKLHYAFQTADKLYIVMDFMIGG----ELFYHLR--RSPIF . ..|.||||.| . .|.| ...|.||.||. . .. .. .| |. ..|.|.||.|...|.. |..|.||... || .|| ... |. | GRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCF --TEEKAAYYSAEIILGIEALHSNNIIYRDLKPENILIDHKGHL----RLADFGLSKKG-VKDHERTNSLCGTPEYLAPEILL-NNGHTKMVDWWSLGAI .|. . | .|. |.| .||..||.|||||||||||..||. ...||||.|. . ....||||.|.|||... ...... ||.||.| | YFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCI IYEMLTGAPPFYNK------NQKQMFKDRFLKPIEMKEWFS---------------------PAAKSLLSGLLNINPELRLGFKGIQEIKEHEFY .||||.| |||... .|.||.. . .|.. .. . ...|......|. .|. |.. ...|..|.. LYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF |
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Kinase | 19784.AA | S_TK_X | 329-388 | 31 | 1.3e-15 | 59.08 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 329-388 Range on HMM: 1-79/79 Sequence Identity: 31% (27 aa) ASINWDKLYK--KEIPPPYKPKLS----SKYDLSHFSKQFTTETVKDTPYCGKTIKDS-------------------YNDFTYQR ..|.|||||. |||.||.|||.. | |.| | . || ||.. | |. . .||| . RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM------LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF |
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Kinase | 19784.AA | TyrKc | 73-327 | 23 | 7.7e-14 | 1.11 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 73-327 Range on HMM: 1-280/280 Sequence Identity: 23% (68 aa) TFGIHVLGKGSFGKVVLVEKKDTKELYAMKILKKDYIQYTNQKFNTQQERDILVKM--NSPFIVKLHYAFQTA-------DKLYIVMDFMIGGELFYHLR ...|| | ||.|.. . | . | | ||.| . .| |. | . | ||.|. . . . |.||| .| .| | .|| ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR RSPI-FTEEKAAYYSAEIILGIEALHSNNIIYRDLKPENILIDHKGHLRLADFGLSKKGVKD------HERTNSLC--GTPE-----YLAPEILLNNGHT .. .. .. ... | | | |||.|.| ||| |.|...... . .|||||... | .. . |. .||| . . | KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT KMVDWWSLGAIIYEMLT-GAPPFYN-----KNQKQMF---KDRFLKPIEMKEW------FSPAAKSLLSGLLNINPELRLGFKGIQEIKEHEF | || | ..|..| |..| .. .. .... |... |. ... .. . . .|| | |. | ..| TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI----HECF |
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Kinase | 19784.AA | Pkinase_Tyr | 76-281 | 27 | 1.2e-07 | 26.54 | Pfam | 4-226 (270) | Show / Hide |
Range on Protein: 76-281 Range on HMM: 4-226/270 Sequence Identity: 27% (61 aa) IHVLGKGSFGKVVLVEKK----DTKELYAMKILKKDYIQYT--NQKFNTQQERDILVKM-NSPFIVKLHYAFQ-TADK--LYIVMDFMIGGELFYHLRR- ...||.|.||.|.. . | .|| | |.|| .. . ..| .| |. .. . | ||.|. . . .|||| .| .| | .||. GKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDF--MREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKH ---SPIFTEEKAAYYSAEIILGIEALHSNNIIYRDLKPENILIDHKGHLRLADFGLSKKG-VKDHE-RTNSLCGTP-EYLAPEILLNNGHTKMVDWWSLG . .| . ....| | | |.|.|.| ||| |.|...... . .||||.. .| |. . . | .||| . .. | | || | REDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFG AIIYEMLT-GAPP-FYNKNQKQMFK ..|..| |. | ... .... VLMWEIFTYGEQPTYPGMSNEEVYE |
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Kinase | 19784.AA | Pkinase_C | 348-371 | 41 | 0.000142 | 19.43 | Pfam | 1-24 (46) | Show / Hide |
Range on Protein: 348-371 Range on HMM: 1-24/46 Sequence Identity: 41% (10 aa) KLSSKYDLSHFSKQFTTETVKDTP ...|. | |.| ..|| |...||| QVKSPTDTSNFDPEFTDEPPMDTP |