Gene 15779 (Tetrahymena)
15779
Sequence
Protein domains of 15779.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 15779.AA | C8 | 42-256 | 60 | 2.5e-118 | 399.41 | In-house | 1-226 (226) | Show / Hide |
Range on Protein: 42-256 Range on HMM: 1-226/226 Sequence Identity: 60% (136 aa) FQKYEYLSSGAYSLVLKAYNSKQKRQVALKFLGSSNQEENDGIESLKKEYEMLQKFSQSQFLVNVYDCFYLMEEQDDEDEDGNDIIVQTGVKSFFVMEME |....|||.|||..||||.|.|..|...|||. ..|......|||..|||||.|.|.|..|.||.|||||.|.|. .|....|..|||| .||.|||||| FNNFQYLSFGAYGMVLKAKNVKDNREIVLKFQKCQNKQDIQNIESIMKEYEMPQVFQQYDFYVNEYDCFYEMYEVFEEEKCSNEKIVQTEEKSCFVMEME LCEKNLKQLFDILRKEQVPPSKELKEIIAIQMIEGLNNLHVKNIMHRDIKPQNFLVCTSQEYGFQIKLCDLGFASAVSKSKS-FVSKK----GTDSYFAP |||.|||||.| .|..|...||| |||||||||.|.|..|.||||||||||.|||||..|.|||.|||||.||||.|||.|| . ||| ||. |||| LCEQNLKQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAP EVEEG------QSRIQSDLFSLGLVL |.|.. |.||||||||.|||| EIEKKQDNQYKQYRIQSDLFSVGLVL |
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Kinase | 15779.AA | Ciliate-C8 | 51-256 | 55 | 1.4e-116 | 393.63 | In-house | 1-238 (238) | Show / Hide |
Range on Protein: 51-256 Range on HMM: 1-238/238 Sequence Identity: 55% (133 aa) GAYSLVLKAYNSKQKRQVALKFLGSSNQEENDGIESLKKEYEMLQKFSQSQFLVNVYDCFYLMEEQDDEDEDGNDIIVQTGVK---SFFVMEMELCEKN- ||...||||.|.||.|.|||||. ..|.......|...|||||...|.|..|.|.||||||||||...||.||||.|||| .| ||||||||.|..| GAFGMVLKAQNKKQNRKVALKFRECVNKIQKNQMEHEIKEYEMIMQFCQMPFVVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKKSFFVMEMEKCQQNC -LKQLFDILRKEQVPPSKELKEIIAIQMIEGLNNLHVKNIMHRDIKPQNFLVCTSQEYGFQIKLCD------LGFASAVSKSKS-FVSKK--GTDSY--- |||.|| .||.|..||.. |||||||||...|.||..|||||||||.||||| .|.|...||||| .||||...|.|| ..||| ||| | NLKQYFDRCRKKQSYPSQQMKEIIAIQMIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEM --------FAPEVEEGQSRIQSDLFS-------LGLVL ||||||..|||||||.|| .|||| YFCGNWGYFAPEVEKKQSRIQSDIFSKKSDSYSVGLVL |
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Kinase | 15779.AA | C2 | 51-269 | 39 | 6.7e-70 | 237.93 | In-house | 1-245 (245) | Show / Hide |
Range on Protein: 51-269 Range on HMM: 1-245/245 Sequence Identity: 39% (96 aa) GAYSLVLKAYNSKQKRQVALKFLGSSNQEENDGIESLKKEYEMLQKFSQSQFLVNVYDCFYLMEE-QDDEDEDGNDIIVQTGV--------KSFFVMEME || .|||||.| ||.|.|||| .. . | ... |||....... . ....||..||| .. ..||||| ...... |.|.|.|.| GAFGLVLKAFNKKQNRHVALKIQ-ECQSNDINGMHEVQKEYGIMRQCQNMPYIIKVYNYFYLTVNKKEDEDEDNDEEEKEQENIKKQKNEKKIFVVYEQE LCEKNLKQLFDILRKEQVPPSKELKEIIAIQMIEGLNNLHVKNIMHRDIKPQNFLVCTSQEYGFQIKLCD----------LGFASAVSKSKS--FVSK-K |..|||| |. .||.. |... |.|.||||. . | || ..| ||||||.|||. .|. ||||| . |||.....|| .|| | FCQGNLKQYFNRCRKQNSYPCQQMKMIMAIQMMDSINYLHRFDIVHRDIKPSNFLYQFDQQGIPTIKLCDYHIQYQKKCDFDFASKLKYNKSRIHFSKFK GTDSY----FAPEVEEGQSRIQSDLFS-LGLVLLELDNFNTLNKNW .| .| |||||... . .||||| .|.||||||| .. . . WTQQYYQHIFAPEVYQNIYKKNSDLFSTVGYVLLELDNMQQYTICC |
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Kinase | 15779.AA | CMGC | 42-220 | 16 | 2.3e-26 | 82.86 | In-house | 1-256 (513) | Show / Hide |
Range on Protein: 42-220 Range on HMM: 1-256/513 Sequence Identity: 16% (42 aa) FQKYEYLSSGAYSLVLKAYN--------------SKQKRQVALKFLGSSNQEENDGI---------ESLKKEYEMLQKFS----------------QSQF ... ... .|.|. | |... . ...||.| . . .|... . | ..|.... . YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN LVNVYDCFYLMEEQDDEDEDGNDIIVQTGVKSFFVMEMELCEKNLKQLFDILRK-----EQVPPSKEL------------KEIIA------IQMIEGLN- .|. ||.|| ... .|.|| . | . . . .|.....|.|. . .. ..| | . . |...||. IVKLYDIFYHKNSDGNEYEDKHII--SQ-HFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKL -NLHVKN--IMHRDIKPQNFLVCTSQEY----------------GFQIKLCDLGFASAVSK .| .. |.|||.||.| |.. |. ...|.|| |.| .... KYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHP |
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Kinase | 15779.AA | Pkinase | 42-259 | 22 | 9.5e-26 | 92.13 | Pfam | 1-205 (293) | Show / Hide |
Range on Protein: 42-259 Range on HMM: 1-205/293 Sequence Identity: 22% (52 aa) FQKYEYLSSGAYSLVLKAYNSKQKRQVALKFLGSSNQEENDGIESLK-KEYEMLQKFSQSQFLVNVYDCFYLMEEQDDEDEDGNDIIVQTGVKSFFVMEM ... . . ||... | |... . ..||.| . ...... .. .. | ...... .. . | ||.|. |. | | YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--------------------KDHIYMVM ELCEKN--LKQLFDILR--KEQVP--PSKELKEIIAIQMIEGLNNLHVKNIMHRDIKPQNFLVCTSQEYGFQIKLCDLGFASA--VSKSKSFVSKKGTDS |.||. . |||... .. . . .|.| .. |...||. .| ..|.|||.||.|.|. . . .|.|| |.| .. . . || EYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMY-QILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPW YFAPEV--EEGQSRIQSDLFSLGLVLLEL | |||| . .| .|.|..| |. YMAPEVIRGGQYYGPKVDMWSCGCILYEM |
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Kinase | 15779.AA | STE | 42-259 | 18 | 1.5e-23 | 80.09 | In-house | 1-261 (359) | Show / Hide |
Range on Protein: 42-259 Range on HMM: 1-261/359 Sequence Identity: 18% (52 aa) FQKYEYLSSGAYSLVLKAYNS------KQKRQ---------VALKFLGSSNQE-ENDG--------------IESLKKEYEMLQKFSQ-SQFLVNVYDCF ... | . .||. | ||.| | ... .| | . .|.. .. .....|| ....|... ... |. |.|. WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY YLMEEQDDEDEDGNDIIVQTGVKSFFVMEMELCE-KNLKQLFD-ILRKEQVPPSKE-------LKEI--IAIQMIEG-LNNLHVKNIMHRDIKPQNFLVC . . .. .. . ||... | .. . . . ... ..| |. | ..| |. || ..|.||||||.| |. FKEGHN-------------HKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL- TSQEYGFQIKLCDLGFASAVSK-----------------SKSFVSKKGTDSYFAPEVEEG-QSR------IQSDLFSLGLVLLEL .|||| |... ... .. . || . |||| .. .. ...| |||....|. --------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEM |
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Kinase | 15779.AA | CAMK | 47-238 | 15 | 4.1e-22 | 67.4 | In-house | 1-291 (425) | Show / Hide |
Range on Protein: 47-238 Range on HMM: 1-291/425 Sequence Identity: 15% (46 aa) YLSSGAYSLVLKAYNSKQK------------RQVALKF------------------------LGSSNQEENDGIES-LKKEYEMLQKFS------QSQFL | .|... | .... . . ..|| |. ......... . ...|.|...| . . . TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI VNVYDCFY------------LMEEQDDEDEDGNDIIVQTGVKSFFVMEM---ELCEKN--LKQLFDILRKE-----------QVPPSKELKEIIAI---- .. |. . . | | .....| | |.|. . ||| ... | .. ..| | IKLYEVYEDPHYFKNTNDYET-SKQ-----------VF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFR QMIEGLNNLHVKNIMHRDIKPQNFLVCTSQEYG-------------FQIKLCDLGFASAVSKSK------------------------SFVSKKGTDSYF |...... .| .||.|||.|| | |.... . ..||..| ||| . ... . || .| QICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYM A-PEV | ||| AAPEV |
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Kinase | 15779.AA | Ciliate-E2 | 169-259 | 25 | 1.9e-21 | 70.36 | In-house | 165-289 (365) | Show / Hide |
Range on Protein: 169-259 Range on HMM: 165-289/365 Sequence Identity: 25% (34 aa) IAIQMIEGLNNLHVKN-IMHRDIKPQNFLVCTSQEYGFQIKLCDLGFASAVSKS----------KSFVSKK-----------------------GTDSYF .. ..|..|. || || |.||||||.| |. ||..|.|.. .... | . | || | YIACIILALEYLHSKNNIIHRDIKPENILF---------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYM APEVEEGQSR----------IQSDLFSLGLVLLEL |||. .|.. ..|..||| .| |. APEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM |
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Kinase | 15779.AA | S_TKc | 42-323 | 21 | 1.3e-20 | 75.74 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 42-323 Range on HMM: 1-231/231 Sequence Identity: 21% (64 aa) FQKYEYLSSGAYSLVLKAYNSKQKRQVALKFLGSSNQEENDGIESLKKEYEMLQKFSQSQFLVNVYDCFYLMEEQDDEDEDGNDIIVQTGVKSFFVMEME ... . . .||.. | |... | .|.||.| . |....| ..|.| . ..|. ||.|. ... | || YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD---------------------DHLYMVME LCEKNLKQLFDILRKEQVP------PSKELKEIIAIQMIEGLNNLHVKNIMHRDIKPQNFLVCTSQEYGFQIKLCDLGFASAVSKSKSFVSKKGTDSYFA .|. .| |||...| . . | . . ... |....|. .| ..|.|||.||.| |... .||.|| |.| . . || | | YCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMY-QICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL------TTFCGTPWYMA PEVEEGQSRIQSDLFSLGLVLLELDNFNTLNKNWIDTKIRYYLFNGEKIPEEKYQIDKNSNIYKIAQICLKPKYLDRTTAGELLS--------QII ||| | .. .| |.| .| |. .. . .. . . . . ||. .| || |.| . . PEVL-GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 15779.AA | Ciliate-E1 | 135-250 | 24 | 1.1e-19 | 61.06 | In-house | 71-202 (202) | Show / Hide |
Range on Protein: 135-250 Range on HMM: 71-202/202 Sequence Identity: 24% (33 aa) FFVMEMELCEKNLKQLFD---------ILRKEQVPPSKELKEIIAIQMIEGLNNLHVKNIMHRDIKPQNFLVCTSQEYGFQIKLCDLGFAS-AVSKSKSF ... .|.|...||. .. .....| . . |. |..|.|.||. || .||.|||||||| |.. . .| .. |.| .. ..... ICIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYC----DFGISKFLKNNQNQQ VSKKGTDSYFAPEVE--------EGQ--SRIQSDLF . .|| .|..|. . . . ..||.. CQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY |
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Kinase | 15779.AA | TKL | 169-259 | 21 | 5.9e-18 | 61.25 | In-house | 137-282 (364) | Show / Hide |
Range on Protein: 169-259 Range on HMM: 137-282/364 Sequence Identity: 21% (31 aa) IAIQMIEGLNNLHV--------KNIMHRDIKPQNFLVCTSQE----------YGFQIKLCDLGFASAVSKSKS--------------------FVSKKGT .|... |.| || ..| |||.|..| || . . .|.||.|.. .|.|.. .. || WALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGT DSYFAPEV-----------------EEGQSRIQSDLFSLGLVLLEL . |||| .... ..| .| |.|| |. PRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEI |
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Kinase | 15779.AA | TKL-Unique | 169-259 | 32 | 1.4e-16 | 55.13 | In-house | 115-221 (290) | Show / Hide |
Range on Protein: 169-259 Range on HMM: 115-221/290 Sequence Identity: 32% (35 aa) IAIQMIEGLNNLHVKN--IMHRDIKPQNFLVCTS-QEYGFQIKLCDLGFASAVSKS-KSFVSKK---------GTDSYFAPEVEEG---QSRIQSDLFSL .||.. |...|| .. |.|||.|..|||| . ..||.|| |.. ||. |.... . |. . |||| .. | ..|| .| MAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSF GLVLLEL | || |. GIVLWEI |
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Kinase | 15779.AA | Ciliate-E1 | 48-112 | 20 | 6.3e-08 | 22.36 | In-house | 1-66 (202) | Show / Hide |
Range on Protein: 48-112 Range on HMM: 1-66/202 Sequence Identity: 20% (14 aa) LSSGAYSLVLKAYNSKQK-RQVALKFLGSSNQEENDGIESLKKEYE-MLQKFSQSQFLVNVYDCFYL ...| .|.|.||.. ... .|||.|. ... . .....||| ... | . . .....|.... IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKI |
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Kinase | 15779.AA | Ciliate-E2 | 42-116 | 13 | 3e-06 | 17.53 | In-house | 1-107 (365) | Show / Hide |
Range on Protein: 42-116 Range on HMM: 1-107/365 Sequence Identity: 13% (14 aa) FQKYEYLSSGAYSLVLKAYNSKQKRQVALK-----------------FLGSSNQEENDGIESLKKEYEMLQ---------------KFSQSQFLVNVYDC . . . . .|... | |. . |...|.|.| .. .. ....||..|.| ... .. .. .... |.| YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FYLMEEQ |. . .. FQEKDDN |
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Kinase | 15779.AA | C8 | 403-604 | 47 | 5.7e-100 | 338.43 | In-house | 1-226 (226) | Show / Hide |
Range on Protein: 403-604 Range on HMM: 1-226/226 Sequence Identity: 47% (108 aa) SNNFQILSFGNFGMVLATKKAKLDNKEIVLKIQKIEDEQLIQNEISIMQKLKEPLVVQLYDSYIIENKLVHDRYSVFELEKCS-----------CSLDE- .||||.||||..||||..|..| ||.|||||.||....| |||..|||.....|.|.|.||.|..|... ...|.|||.|||| |...| FNNFQYLSFGAYGMVLKAKNVK-DNREIVLKFQKCQNKQDIQNIESIMKEYEMPQVFQQYDFYVNEYDCFYEMYEVFEEEKCSNEKIVQTEEKSCFVMEM ----------YLERQNKEGQLNEENKFQMAIQIIDSVNYIHQFNIIHRDIKPENFLVYLDGKQA-KIKLCDFGLSAQIPDNQDSIQTIER--IGNFGYSA |.||.||..|...|.|...|||.||.|||||..||.||||||.||||.||... .|||||||...|...|...||... .|...|.| ELCEQNLKQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFA PEILNKNDNELKFYTKKSDSYSVGLLL |||..|.||..|.|...||..||||.| PEIEKKQDNQYKQYRIQSDLFSVGLVL |
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Kinase | 15779.AA | Ciliate-C8 | 412-604 | 39 | 7.9e-97 | 327.99 | In-house | 1-238 (238) | Show / Hide |
Range on Protein: 412-604 Range on HMM: 1-238/238 Sequence Identity: 39% (93 aa) GNFGMVLAT------KKAKLDNKEIVLKIQKIEDEQLIQNEISIMQKLKEPLVVQLYDSYIIENKLVHDR-----------------YSVFELEKCS--C |.|||||.. .| .|...|.|.||||...|..|.....|||....|.|||.||....... . .. ..|.|.|||. | GAFGMVLKAQNKKQNRKVALKFRECVNKIQKNQMEHEIKEYEMIMQFCQMPFVVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKKSFFVMEMEKCQQNC SLDEYLER-QNKEGQLNEENKFQMAIQIIDSVNYIHQFNIIHRDIKPENFLVYLD-GKQAKIKLCD------FGLSAQIPDNQD---------SIQTIER .|..|..| ..|....... |...|||.||||||.|.|||.||||||.||||..| ..| ||||| ||...|.|.|.. ..|.|| NLKQYFDRCRKKQSYPSQQMKEIIAIQMIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEM --IGNFGYSAPEILNK-NDNELKFYTKKSDSYSVGLLL .||.||.|||...| .........||||||||||.| YFCGNWGYFAPEVEKKQSRIQSDIFSKKSDSYSVGLVL |
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Kinase | 15779.AA | C2 | 412-617 | 28 | 2.8e-43 | 145.72 | In-house | 1-245 (245) | Show / Hide |
Range on Protein: 412-617 Range on HMM: 1-245/245 Sequence Identity: 28% (72 aa) GNFGMVLATKKAKLDNKEIVLKIQKIED-----EQLIQNEISIMQKLK-EPLVVQLYDSYIIENKLVHD-------------R----------YSVFELE | ||.|| . | .|....||||.... .. .|.|..||.... |.....|... . | . |.|.| GAFGLVLKA-FNKKQNRHVALKIQECQSNDINGMHEVQKEYGIMRQCQNMPYIIKVYNYFYLTVNKKEDEDEDNDEEEKEQENIKKQKNEKKIFVVYEQE KCSCSLDEYLERQNKEG-QLNEENKFQMAIQIIDSVNYIHQFNIIHRDIKPENFLVYLDGKQA-KIKLCD----------FGLSAQIPDNQDSIQTIERI .|.. | |..|. |. ..... | .||||..||.||.|.|.|.||||||.|||. .| .. ||||| | . .. |. | . . FCQGNLKQYFNRCRKQNSYPCQQMKMIMAIQMMDSINYLHRFDIVHRDIKPSNFLYQFDQQGIPTIKLCDYHIQYQKKCDFDFASKLKYNKSRIHFSKFK GNFGY----SAPEILNKNDNELKFYTKKSDSYS-VGLLLALLDNYQDLKTNT . | .|||. . . | |.|| .| ||. | ||| | . WTQQYYQHIFAPEV------YQNIYKKNSDLFSTVGYVLLELDNMQQYTICC |
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Kinase | 15779.AA | CAMK | 408-604 | 19 | 1.1e-34 | 108.65 | In-house | 1-324 (425) | Show / Hide |
Range on Protein: 408-604 Range on HMM: 1-324/425 Sequence Identity: 19% (62 aa) ILSFGNFGMVLATKKAKLDN-----------KEIVLKI---QKIE----------------------------DEQLIQNEISIMQK-------LKEPLV .| |.|| | . . . .. || .|. |.. ...||.||.| |. | . TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI VQLYDSYI------------IENK-LVHD--RYSVFEL---EKCSC-----SLDEYLERQNK------------EGQLNEENKFQMAIQIIDSVNYIHQF ..||. | .| . . .. .. . | || | .|. .. . .| ..|. .. ||.. |.|.|. IKLYEVYEDPHYFKNTNDYET-SKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH NIIHRDIKPENFLVYLDG--------------KQAKIKLCDFGLSAQIPDNQDSI---------------------QTIERIGNFGYSA-PEILNKN--- ||.|||.|||| |. .. ....||..|||........... .. | .| | ||.||.. NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC ------DNELKFYTKKSDSYSVGLLL |.| . |..|.| |.| .| NMQNATDEEKPYYGPKCDMWSCGVIL |
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Kinase | 15779.AA | S_TKc | 403-676 | 23 | 1.4e-31 | 112.18 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 403-676 Range on HMM: 1-231/231 Sequence Identity: 23% (69 aa) SNNFQILSFGNFGMVLATKKAKLDNKEIVLKIQKIEDEQLIQNEISIMQKLKEPLVVQLYDSYIIENKLVHDRYSVFELEKCSC---SLDEYLERQNKEG ... | || | .. | .... .|| | . |..||.|..| . | .|.|||.. .. | |.|. |. .| .|.......| YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEY--CDGDLGDLFDYIKKRGRHG Q---LNEENKFQMAIQIIDSVNYIHQFNIIHRDIKPENFLVYLDGKQAKIKLCDFGLSAQIPDNQDSIQTIERIGNFGYSAPEILNKNDNELKFYTK-KS ..| .. ||.. ..|.|. .|||||.|||| |. ||.|||||..|. .| | |||.| |.| |. LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL---------TTFCGTPWYMAPEVL--------GYGKCKC DSYSVGLLLALLDN----YQDLKTNTTSIFSLMTQKQLDKPFEKSNIQINKNSEIYKFINLLVVSDSDQRASLYDIVK-QSD---ETFF | .|.| .|. . .. . .| .. .| ||. . . | ..| . .. . ..| .| DWWSCGCILYEMLCGYPPFP----QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 15779.AA | Ciliate-E1 | 409-598 | 26 | 4.2e-30 | 95.33 | In-house | 1-202 (202) | Show / Hide |
Range on Protein: 409-598 Range on HMM: 1-202/202 Sequence Identity: 26% (56 aa) LSFGNFGMVLATKKAKLDNKEIVLKIQKIEDEQ-------LIQNEISIMQKLKEPL-VVQLYDSYIIENKLVHDRYSVFELEKCSCSLDEYLE------- .. | |..|. |. . .... .||..... . .|.....||. .|. ..|..| ..|.. ... .. .|.|.||| .||. IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYIC----IIIFECCCCSLKDYLQNHNRLEY ---RQNKEGQLNEENKFQMAIQIIDSVNYIHQFNIIHRDIKPENFLVYLDGKQAKIKLCDFGLSAQIPDNQDSIQTIERIGNFGYSAPEILNK---NDNE |....|.....| |...|.|| ....||.|||||||||.| |.. . .. .. |||.| .. ||.. |. .. |. || .| . |. WQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQ-GNYVYC--DFGISKFLKNNQNQ-QCQYKGYTHYYYPPEQYNCPEQEHNK LKFYTKKSDSY . ...||| | NQKINYKSDIY |
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Kinase | 15779.AA | STE | 404-604 | 22 | 5.3e-27 | 92.45 | In-house | 1-258 (359) | Show / Hide |
Range on Protein: 404-604 Range on HMM: 1-258/359 Sequence Identity: 22% (60 aa) NNF-QILSFGNFG-MVLATKKAKL-------------DNKEIVLKIQKI--------------------EDEQLIQNEISIMQKLK--EPLVVQLYDSYI . ... |.|| ..| .. . .. . |. .. |..| |..||.||.|.. | .|. |..|. WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF IEN--KLVHDRYSVFELEKCSC-SLDEYLE-RQNKEGQLN----------EENKFQMAIQIIDS-VNYIHQFNIIHRDIKPENFLVYLDGKQAKIKLCDF |. . .| .. .| .. |||. .. . . ..|| |. .. ||. .|.|. .|||||||| | |. .||||| KEGHNHKNDDELWIC-MEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL--------VKLCDF GLSAQIPDNQDSI--------------QTIERIGNFGYSAPEILNKNDNE-LKFYTKKSDSYSVGLLL |...|. |. ..| .. .| . |||....|.. | |. |.| .|.|... GVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTI |
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Kinase | 15779.AA | Ciliate-E2 | 403-604 | 21 | 1.2e-26 | 88.44 | In-house | 1-286 (365) | Show / Hide |
Range on Protein: 403-604 Range on HMM: 1-286/365 Sequence Identity: 21% (64 aa) SNNFQILSFGNFG-----MVLATKKA-----------------KLDNKEIVLKIQKIEDEQLIQNEISIMQ----------------KLKEPLVVQLYDS . ... .|||| | ..| | ..|.. .||.| . . | .||.||. .|. | ....|.. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC YIIENK----LVHDRYSVFELEK-----CSCSLDEYLERQNKEGQLNEENKFQMAIQIID---------------SVNYIHQFN-IIHRDIKPENFLVYL .. ... || . .. .|.. . ... | . . ....|. .. ||.. ..|.|. | |||||||||| |. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIE--K-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-- DGKQAKIKLCDFGLSAQIPDNQD--------SIQTIER----------------------IGNFGYSAPEILNKNDNE----LKFYTKKSDSYSVGLLL ||..||||| .. |... . . . .|. || ||||||. ... | |..|.| .|.| .| ------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL |
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Kinase | 15779.AA | Pkinase | 403-605 | 26 | 7.6e-25 | 88.94 | Pfam | 1-203 (293) | Show / Hide |
Range on Protein: 403-605 Range on HMM: 1-203/293 Sequence Identity: 26% (59 aa) SNNFQILSFGNFGMVLATKKAKLDNKE--IVLKIQKIEDEQLIQN-------EISIMQKLKEPLVVQLYDSYIIENKLVHDRYSVFELEKCSC-----SL ... |.|| | .|.. . . ..|| | ..| .. ||.||..|. | .|.|||.. ... . .| | . .| YHIGRKIGSGSFGCV---YKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDL DEYLERQNKEGQL--NEENKFQMAIQIIDSVNYIHQFNIIHRDIKPENFLVYLDGKQ-AKIKLCDFGLSAQIPDNQDSIQTIERIGNFGYSAPEILNKND .|... ..| . |. .. ||. ..|.|. .|||||.||||.|. .| |..|.|||||..|. . . . . | .| |||... FDYIST-WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIR--- NELKFYTKKSDSYSVGLLLA . . |..|.| .|.|..|. -GGQYYGPKVDMWSCGCILY |
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Kinase | 15779.AA | TKL | 487-604 | 23 | 4.6e-23 | 79.9 | In-house | 124-279 (364) | Show / Hide |
Range on Protein: 487-604 Range on HMM: 124-279/364 Sequence Identity: 23% (39 aa) S-LDEYLERQNKEGQLNEENKFQMAIQIIDSVNYIHQFN--------IIHRDIKPENFLVYLDGK-----------QAKIKLCDFGLSAQIP---DNQDS | |. .. . ....|..| .|| |. | |||||.|..| || ... . ..|.|||||| . ...|. SLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDT I--------------QTIERIGNFGYSAPEILNKNDNELKF-----------YTKKSDSYSVGLLL .|. ..|.... |||.|....| . |..|.| || |..| MTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVL |
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Kinase | 15779.AA | CMGC | 406-554 | 16 | 5.7e-22 | 68.16 | In-house | 1-251 (513) | Show / Hide |
Range on Protein: 406-554 Range on HMM: 1-251/513 Sequence Identity: 16% (42 aa) FQILS---FGNFGMVLATKKAKLD-------------NKEIVLKIQKIEDEQLIQ---------------NEISIMQKLK-----------------EPL ..|.. | .|.| . . . |... .|. | . .| ||.|...|. .. YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN VVQLYDSYIIEN------------KLVHDRYSVFELEKCSCSLDEYLERQN--KEG-QLNEENKFQ---------------MA------IQIIDSVN--Y .|.|||.. .| .. |... . | . ..| .|..... . | . .. . . . ||. ... | IVKLYDIFYHKNSDGNEYEDKHIISQ-HFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKY IHQFN--IIHRDIKPENFLVYLDGKQ-----------------AKIKLCDFGLS .|. . |||||.|||| |. ... ..|.|||||. CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLA |
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Kinase | 15779.AA | TKL-Unique | 487-599 | 34 | 4.7e-21 | 71.12 | In-house | 86-213 (290) | Show / Hide |
Range on Protein: 487-599 Range on HMM: 86-213/290 Sequence Identity: 34% (46 aa) SLDEYLER-------QNKEGQLNEENKFQMAIQIIDSVNYIHQFN--IIHRDIKPENFLVYLDGK----QAKIKLCDFGLSAQIP-DNQDSIQTI----- ||...| . |.. || ... .|||.| . .|.| . |||||.|. |||| | . . .||.|||||| .|. .. .. SLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLV--DNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRN -ERIGNFGYSAPEILNKNDNELKFYTKKSDSYS .|.|.| ..|||.|. | . |..||| || QTRCGSFRWMAPEVLRMNF---CQYSEKSDVYS |
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Kinase | 15779.AA | TyrKc | 403-671 | 20 | 2.1e-10 | -54.61 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 403-671 Range on HMM: 1-280/280 Sequence Identity: 20% (61 aa) SNNFQILSFGNFGMVLATKKAKLDNKEIVLKIQKIEDEQLIQNEISIMQKL--KEPLVVQLYDSYIIENK-----LVHDRYSVFELEKCSCSLDEYLERQ ..| |.|| | |.... . | | . .. . .|..|| || . | .|.|| .. . .. . |.|. . .|..|| . ITLGKKLGEGAFGEVY---KGTWK-IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLY--GVCTQQGRNFMYIEPLMIVMEYMPH-GDLKDYLRKH NKEGQLNEENKFQMAIQIIDSVNYIHQFNIIHRDIKPENFLVYLDGKQAKIKLCDFGLSAQIPDN------QDSIQT----IER-IGNFGYSAPEILNKN .. |. . . ....|| . .|.|. |.||||. | || .. .| .||||| | | .| . . .. ||| . RPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--- DNELKFYTKKSDSYSVGLLL----ALLDNYQDL-----KTNTTSIFSLMTQKQLDKPFE----KSNIQINKNSEIYKFINLLVVSDSDQRASLYDIVKQS . .| ||| .| | .. . . ..|. | ... . ...| . . .|.|. . | ..| . .|... --NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF---VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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LRR_RI | 15779.AA | LRR_RI | 710-737 | 21 | 0.001928 | 17.7 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 710-737 Range on HMM: 1-28/28 Sequence Identity: 21% (6 aa) NYNIVTIDLEENSIRDADAKDLATGIAQ | .. ...|. | . |. .. |. |... NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | 15779.AA | LRR_RI | 746-767 | 36 | 0.021628 | 10.29 | SMART | 7-28 (28) | Show / Hide |
Range on Protein: 746-767 Range on HMM: 7-28/28 Sequence Identity: 36% (8 aa) LHLSQNSIGAQGAKDLATGIAQ |.||.| .|. |.. |. |... LWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | 15779.AA | LRR_RI | 770-797 | 28 | 0.062649 | 7.03 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 770-797 Range on HMM: 1-28/28 Sequence Identity: 28% (8 aa) NITNLMLDLQGNSIGAQGAKYLATGISL | . . |.|..| .|. |.. |. |.. NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | 15779.AA | LRR_RI | 800-827 | 28 | 0.002247 | 17.23 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 800-827 Range on HMM: 1-28/28 Sequence Identity: 28% (8 aa) NITNLTLDLQGNSIGDVGAKHLSTVIEQ | . ..|.|..| .|| |...|. .... NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | 15779.AA | LRR_RI | 830-857 | 32 | 0.001299 | 18.91 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 830-857 Range on HMM: 1-28/28 Sequence Identity: 32% (9 aa) NITSLTLDLWDNSIGDKGVKDLATGIAQ | . ..|.|..| .||.|.. |. |... NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | 15779.AA | LRR_RI | 860-887 | 32 | 0.013609 | 11.71 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 860-887 Range on HMM: 1-28/28 Sequence Identity: 32% (9 aa) NITSLKLDLSFNSIGAQGAKDLATGIAQ | . ..|.|| | .|. |.. |. |... NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | 15779.AA | LRR_RI | 890-917 | 35 | 0.002778 | 16.58 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 890-917 Range on HMM: 1-28/28 Sequence Identity: 35% (10 aa) NITNLMLDLQGNSIGDEGAKDLALGIEQ | . . |.|..| .||||.. |. |... NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | 15779.AA | LRR_RI | 920-947 | 32 | 0.014669 | 11.48 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 920-947 Range on HMM: 1-28/28 Sequence Identity: 32% (9 aa) NITSLTLDLWRNSIGDQGSKDLATGIEQ | . ..|.|. | .|| | . |. |... NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | 15779.AA | LRR_RI | 980-1007 | 35 | 0.024403 | 9.92 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 980-1007 Range on HMM: 1-28/28 Sequence Identity: 35% (10 aa) NITSLTLHLSRNSIGDQGAKYLDTGIEQ | . ..|.|| | .|| |.. | |... NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | 15779.AA | LRR_RI | 1010-1037 | 28 | 0.016934 | 11.04 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1010-1037 Range on HMM: 1-28/28 Sequence Identity: 28% (8 aa) NITSLMLDLSDNSIDAQGAKDLAKGISQ | . . |.||.| . . |.. |..|... NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | 15779.AA | LRR_RI | 1040-1067 | 35 | 0.002391 | 17.04 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1040-1067 Range on HMM: 1-28/28 Sequence Identity: 35% (10 aa) NITNLMLDLQQNSIGDEGAKDLATGIAQ | . . |.|..| .||||.. |. |... NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | 15779.AA | LRR_RI | 1070-1097 | 32 | 0.006281 | 14.08 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1070-1097 Range on HMM: 1-28/28 Sequence Identity: 32% (9 aa) NITCLTLDLWRNSIGDQGSKYLATGIEQ | . ..|.|. | .|| | . |. |... NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | 15779.AA | LRR_RI | 1202-1220 | 36 | 0.226532 | 3.09 | SMART | 10-28 (28) | Show / Hide |
Range on Protein: 1202-1220 Range on HMM: 10-28/28 Sequence Identity: 36% (7 aa) RGNSIGDEGAKDLATGIAQ ..| .||||.. |. |... SNNKLGDEGCRQLCEGLKH |
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LRR_RI | 15779.AA | LRR_RI | 1223-1250 | 32 | 0.002742 | 16.62 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1223-1250 Range on HMM: 1-28/28 Sequence Identity: 32% (9 aa) NITNLTLDLSGNSIGAQGAKDLATGISQ | . ..|.||.| .|. |.. |. |... NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | 15779.AA | LRR_RI | 1253-1280 | 32 | 0.019044 | 10.68 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1253-1280 Range on HMM: 1-28/28 Sequence Identity: 32% (9 aa) NITSLTLHLQRNSIGDEGAKDLATTIVQ | . ..|.|. | .||||.. |. .. . NCSLRELWLSNNKLGDEGCRQLCEGLKH |