Gene ALK1 (Bakers Yeast)
ALK1
Sequence
Protein domains of ALK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | ALK1.AA | DUF3635 | 649-760 | 38 | 4e-64 | 222.68 | Pfam | 1-121 (121) | Show / Hide |
Range on Protein: 649-760 Range on HMM: 1-121/121 Sequence Identity: 38% (47 aa) LFFLNGKDKSKINEYQYQFEFEIYQSMRILLNM--DASAFEPMTNLYWLYYLSRVLL-KFGDRKLG--KNDANRDKMARVINHLEMNLAVHKRGGQLFKR ..|..||.|||||||||...|.||..||..|.. ..|.|.||||..||.||...|| |....... ...|.|..|...|||..|..|.||...|.|.. HDFFQGKGKSKINEYQYDYQFDIYRMMRKMLKNPICWSQFHPMTNVLWLHYLIHKLLHKMKFKSICTENTAAMRMYMKKIINHHLMDPARHKHFHQIFMS LETEDIKNTGDLLKLY----K .|...|......|... | FESASIRHCQHYLFNWVRQMK |
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Kinase | ALK1.AA | Haspin | 561-732 | 11 | 1e-39 | 138.25 | In-house | 1-237 (264) | Show / Hide |
Range on Protein: 561-732 Range on HMM: 1-237/264 Sequence Identity: 11% (27 aa) LYLYLLFKDHGTPISLISLK--NWKQILKIFWSCA------------------GIIHGLEKNLKFEHRNLTLDNILIDGNGNITIIDFKCSR-LQTPQDD .. .. ....|...| . . .. .|..|.||| .|. ..|. |..|||.........|....|....||.. |....|. NCKKIGEGCYGEVFSVTWNGKEVVMKIIPIHWSCCKYYGEYCGEHQQTNDEALNEIIIMKKMGKLSHRNMCPNFPNFCGMCVVTQVPGKCCKKLNKMWDH VLYLR---------------LDHPLFFLNGKDKSKINEYQYQFEFEIYQSMRILLN--MDASAFEPMTNLYWLYYLSRV--------------------- . |.. ..|......|................|.. ...... .. ......|......... YCYTHHSENDRPDFFKKNQLHIHWIMEYGGRPLDNFRWKFNTCNQCISIMCQLVMSMYIAKDEMQFWHNDLHWGNVLIKRKTKKKWLHYTMDGKTIKIKS ------LLKFGDRKLGKNDANRDKMARVINHLEMNLA ...|.....||.......... ......... HGVMVTIIDFCKSRCGKDNKKIYWDWKNDETMFEQFW |
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Kinase | ALK1.AA | NuaK | 607-628 | 59 | 5.3e-07 | 13.88 | In-house | 122-143 (252) | Show / Hide |
Range on Protein: 607-628 Range on HMM: 122-143/252 Sequence Identity: 59% (13 aa) HRNLTLDNILIDGNGNITIIDF || | | ||| | |.|. | || HRDLKLENILLDQNCNAKIADF |
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Kinase | ALK1.AA | MARK | 607-628 | 62 | 7.9e-07 | 18.54 | In-house | 127-150 (262) | Show / Hide |
Range on Protein: 607-628 Range on HMM: 127-150/262 Sequence Identity: 62% (15 aa) HRNLTLDNILIDGNG--NITIIDF || . ..||||| || || |||| HRDIKPENILIDENGNHNIKIIDF |
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Kinase | ALK1.AA | Ciliate-E9 | 607-628 | 54 | 2.2e-05 | 12.72 | In-house | 135-156 (298) | Show / Hide |
Range on Protein: 607-628 Range on HMM: 135-156/298 Sequence Identity: 54% (12 aa) HRNLTLDNILIDGNGNITIIDF || | ..|.||| | |. |.|| HRDLKPENMLIDKNYNMKICDF |
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Kinase | ALK1.AA | Ciliate-E2-Unclassified | 607-628 | 52 | 3.4e-05 | 13.99 | In-house | 167-191 (352) | Show / Hide |
Range on Protein: 607-628 Range on HMM: 167-191/352 Sequence Identity: 52% (13 aa) HRNLTLDNILIDGNG---NITIIDF ||.....|||.| || .| |||| HRDIKPENILFDNNGKNYYIKIIDF |
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Kinase | ALK1.AA | CAMKL | 607-628 | 58 | 6.8e-05 | 11.39 | In-house | 150-173 (297) | Show / Hide |
Range on Protein: 607-628 Range on HMM: 150-173/297 Sequence Identity: 58% (14 aa) HRNLTLDNILIDGNG--NITIIDF || . ..|||.| || || |||| HRDIKPENILLDENGNNNIKIIDF |
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Kinase | ALK1.AA | AGC | 602-628 | 37 | 0.000143 | 6.16 | In-house | 171-199 (395) | Show / Hide |
Range on Protein: 602-628 Range on HMM: 171-199/395 Sequence Identity: 37% (11 aa) N-LKFEHRN-LTLDNILIDGNGNITIIDF . ... || | ..|||.| .|.| . || SHMGIIHRDYLKPENILLDEDGHIKLTDF |
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Kinase | ALK1.AA | Ciliate-E2 | 607-639 | 33 | 0.000211 | 11.0 | In-house | 184-211 (365) | Show / Hide |
Range on Protein: 607-639 Range on HMM: 184-211/365 Sequence Identity: 33% (11 aa) HRNLTLDNILIDGNGNITIIDFKCSRLQTPQDD ||.. ..|||. | |||| |. .... . HRDIKPENILF-----IKIIDFGLSKKYDDDNQ |
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Kinase | ALK1.AA | DDR | 602-632 | 36 | 0.000419 | 10.27 | In-house | 152-184 (306) | Show / Hide |
Range on Protein: 602-632 Range on HMM: 152-184/306 Sequence Identity: 36% (12 aa) NLKFEHRNLTLDNILIDGNGNITIIDFK--CSR .. | || |. |.|......| | || || SMNFVHRDLATRNCLVGKEYHIKICDFGTVMSR |
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Kinase | ALK1.AA | CAMK | 607-628 | 35 | 0.000431 | 8.29 | In-house | 202-240 (425) | Show / Hide |
Range on Protein: 607-628 Range on HMM: 202-240/425 Sequence Identity: 35% (14 aa) HRNLTLDNILIDGN-----------------GNITIIDF || | ..|||.| | .|| |||| HRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDF |