Gene QkgA_C2d (Slime mold)

QkgA_C2d

Species: Slime mold
Alias: QkgA_C2d, DDB0217231, DdisK296
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: LRRK

Sequence

Name Sequence Type Origin Length Description Download
QkgA_C2d.AA Protein None 1553 None Fasta, JSON
QkgA_C2d.kin_dom Protein Kinase Domain None 289 None Fasta, JSON

Protein domain

Protein domains of QkgA_C2d.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRR_1 QkgA_C2d.AA LRR_1 311-332 33 0.00057 18.25 Pfam 1-26 (26) Show / Hide 
Range on Protein: 311-332
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

QLVELDMSN-N--RIT-EIPIE-ITEL
.| .||.|. |  ..| .|| . .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 QkgA_C2d.AA LRR_1 334-355 33 0.123236 9.97 Pfam 1-26 (26) Show / Hide 
Range on Protein: 334-355
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

FLKNLNLSD-N--LIN-DIPLE-ICNL
 |. |.||. |   .  .|| . . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 QkgA_C2d.AA LRR_1 357-378 29 3.925256 4.64 Pfam 1-26 (26) Show / Hide 
Range on Protein: 357-378
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

LLKVLLLNE-N--PLN-NFPSS-IVEL
 |..| |.  |  .|  ..|.| .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
ROC QkgA_C2d.AA ROC 399-611 23 4e-36 118.59 In-house 1-215 (215) Show / Hide 
Range on Protein: 399-611
Range on HMM: 1-215/215
Sequence Identity: 23% (60 aa)

WNKVKLMFVGEEGVGKTRLCKLLIGSKYNKKKSSSSSSSSLSSLSSALSSSSSSSSIINSNSISNSNINMVNIKNENQVTGDTVSTEGVN-IHDFK----
 | .|||..|..||||| ||| |...|.  . ..|                                             |. ..| |.. |....    
CNEMKLMLCGQGGVGKTSLCKQLMHDKFSDCSCYSC------------------------------------------DKGNHPTTHGIEPIQQWVLDCK

-------SKKVEFYAWDFGGQQIFYPTHQFFLTT-QSLYLLIFRVND-----SNF----AER--VNYWVHQIKAKSGIS-------LPIIFFVGTHIDSC
       .... |  ||||||.|...|||||||. .|.|||..   .     ...     ..  . ||   ||. .. |        |.|  ||||.| .
DMMFRKKEDEIKFNVWDFGGQEIYHATHQFFLTNHRSVYLLVWDCRTKCCDGQPEMIVRECNYELEYWLRFIKSRGPQSEHHCMQPSPVI-IVGTHWDKV

TPEQLS-----MAESILKSNFIKYSRV-K--------QNVINFVSCVTG-KGVKELKKR
  .. .     . . . .    |. .. .        | ... |.| || ||...|.. 
PRQDNKVYQHKQCCRMWQKLRNKFPNICHSWMQIEHYQGFFH-VDCETGCKGIDKLRHH
Miro QkgA_C2d.AA Miro 502-565 24 0.000689 16.09 Pfam 73-140 (140) Show / Hide 
Range on Protein: 502-565
Range on HMM: 73-140/140
Sequence Identity: 24% (17 aa)

WDFGGQQIFYPTHQFF--LTTQSLYLLIF-RVNDSNFAERVNY--WVHQIKAKSGIS-LPIIFFVGTHID
||.||. ... .|..|  ... . ... .   ....|.. .||  |  ... |.|.. .|.| .||...|
WDCGGREYWKFEHMHFACMKWADAICFVYDCTDYESFNRVSNYMAWLPHFR-KWGKKAIPVI-VVGNKCD
Miro QkgA_C2d.AA Miro 403-415 38 4.872501 2.35 Pfam 1-13 (140) Show / Hide 
Range on Protein: 403-415
Range on HMM: 1-13/140
Sequence Identity: 38% (5 aa)

KLMFVGEEGVGKT
|.. .| .|.||.
KVVVCGDKGCGKS
COR QkgA_C2d.AA COR 697-893 22 7.8e-46 146.45 In-house 40-288 (434) Show / Hide 
Range on Protein: 697-893
Range on HMM: 40-288/434
Sequence Identity: 22% (58 aa)

LQQSIKEKYIDYDDYLNECKLSY-----------LKPHEIKDATDFLHNLGIILHFD----SPKLNNLVVLDPQWLADVMSSLITFSHSW-----IKLGI
............ .... |. .            ....|.. ....||.||.|.||.     |.|...|||||||....|.....  .|       . ||
MNRHNEKPWMSWKEFCQICQEHGPPKRLRHQNIIIDEDELHTVAMYLHDLGHIIHFKIWDHDPMLKDFVVLDPQWFCQMMYHIFNHKESRCFHKLHNKGI

-LNHSDLQSIWGG-----------RYKQTLWPSLLKLLEKFEVSYQLPN---------LSKSLIPSLLPDDPIGEI-LEIKDREWVPLKLAMENNYVQVF
 ..|.||. || .           ||.... . |..|.||||..|....          . .|||.|||||  ..  .. ..  |        . . ...
FFTHQDLEKIWNPPCRHNPHMNWRRYPDHDHEYLVELMEKFELCYPIDPDWTHFWHQETTTYLIPQLLPDDRPQHWEWWQWPQ-W-----ETNEHDCRYL

GCDYHF------SFMPLGFFARLLLRILLIQGIDIKT----------YWKDGVLL
.. ||.       |.| ||. |.. |.. ..  . |.          ||..|..|
RRHYHYCMDHHHMFLPAGFWPRFQVRLHHFIHDMFKCFYERSCCEWMYWRNGMVL
COR QkgA_C2d.AA COR 931-1224 6 3.3e-08 22.37 In-house 322-434 (434) Show / Hide 
Range on Protein: 931-1224
Range on HMM: 322-434/434
Sequence Identity: 6% (20 aa)

DSQNYSPLEPPPLILNSPRVNRKFISNSTSTTSTTTSTTSTSTTSSNNITPLSMSSITPYSPTSPRTPSFSSSSTTTSSSSSSSSPSSQFCGVGCHRNIN
|                                                                                                   
D---------------------------------------------------------------------------------------------------

KNNGSSNELIKTLTKINNQNGSSGELIKTTTTTSTSTSTTSTTTPTTTTPTIPIKNNNNKKLPINRTVSSLCLTAKPKLQALITFIKKKSFEQSHDNDSY
                                                                                                    
----------------------------------------------------------------------------------------------------

KLNIQVRTYNTTIDKEHSVSLFFQQLLFTIDTLISGSY--QGLE-------VTRTIPCTHCIQLNP--TIEPYHFDLGDCISALEDGRSHVYCGNDP---
                 . . ..|..  .|. .   ..   ||.       .   ||| |||| ..     .. . ...|| | |.|.  ..|..     
-----------------MCCQLWQIIRQHIQHIHNSWWPWPGLQYQCQHWVCREWIPCPHCIQDHWDTCCDICYYQYDWCIRAEEMGMDSYPCPKCDQYC

--------------------NTPV-RIDY
                    . .. ||..
DAFEMMCCYQHHWHYSHDQNGQWIQRISD
Kinase QkgA_C2d.AA LRRK 1242-1530 40 1.5e-164 552.95 In-house 1-351 (351) Show / Hide 
Range on Protein: 1242-1530
Range on HMM: 1-351/351
Sequence Identity: 40% (143 aa)

ILYERQIGEGGFG-LIHKGKLIS-------------------------NKS-DIAIKSLILC---------NSNNNNNSNNNNNSNNSNNFKNNNNEDEF
. .|.|||.|||| .....|...                         ... ..|||.....         |||||||.||||  ...... ...|....
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNN--SEQVED-MDQNHEDC

IEKFQEFQHEVFIMSNLNHPNIVKLYGLMHNPPRMVMEYVEHGDLYHLCQDKERYA------SLGWTLKLRLMIDIAKGIGYMQNQNPPIVHRDLRSPNI
...|.||.|||.|||.|||||||.|.|....|..|||||. ||||||....|....      ...|.|||.....||||..|....||||.||||.||||
CRAFREFRHEVWIMSHLNHPNIVSLKGFCIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNI

FLKSLDEN-------SPVCAKIADFGLSQ--QSVYS--VSGLLGNFQWMAPETIGVE-DESYTEKVDTYSFAMILFTILTGE-IPFDEYS-FGKMQFINL
.|.|...|        .|||||||||.|.  |....  ..|..||..|||||... . .|.||||||.|||.|||...||.. .||||.. |..||....
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQ

IRE---ENLRPTLPFD-CDP-----RLSNLIQLCWSTNPKKRPSFTFIIKELLE
|..   | ||||.|.. | |     ....|||.||...|||||.|. |.| | .
IEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase QkgA_C2d.AA TKL 1248-1528 28 4e-100 338.94 In-house 1-364 (364) Show / Hide 
Range on Protein: 1248-1528
Range on HMM: 1-364/364
Sequence Identity: 28% (108 aa)

IGEGGFGLIHKGKLISNK--------SDIAIKSLILCN-SNNNNNSNNNNNSNNSNNFKNNNNEDEFIEKFQEFQHEVF-IMSNLNHPNIVKLYG-----
||.|||| ..|||.  .          |.|.| .   | .... ||..||. ||.... . ...|.....|..|  |.  .||.|.|||||...|     
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENND-NNNYSD-M-QLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCP

----LMHNP------PRMVMEYVEHGDLYHLCQDKERYASLGWTLKLRLMIDIAKGIGYMQNQN------PPIVHRDLRSPNIFLKSL---------DEN
     ...|      . .||||...|.|.|. .         | ...|...|||.|. |. ..|      |||.|||| |.||....          ..|
PCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPN

SPVCAKIADFGLSQQSVYS----------------------VSGLLGNFQWMAPETIGVED--------------ESYTEKVDTYSFAMILFTILTGEIP
...|.||.|||||.    |                       .   |...||||| .  ..              ..|.||.| |||...|. |||...|
ADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRP

FDEYSFGKMQ-------FINLIREENLRPTLP------------FDCDPRLSNLIQLCWSTNPKKRPSFTFIIKEL
...| .  |.       .. .. ...|||..|             ||.|....|.| ||...|.|||||. |.|.|
YYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase QkgA_C2d.AA TKL-Unique 1307-1528 33 4.3e-63 215.91 In-house 37-290 (290) Show / Hide 
Range on Protein: 1307-1528
Range on HMM: 37-290/290
Sequence Identity: 33% (85 aa)

EKFQEFQHEVFIMSNLN-HPNIVKLYGLMH----NPP--RMVMEYVEHGDLYHLCQD-------KERYASLGWTLKLRLMIDIAKGIGYMQNQNPPIVHR
|. |||  || .|..|. |||||...|  .     ||   .||||...| || . ..        ..   | . ..... ||||.|  |  . .||| ||
EMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHR

DLRSPNIFLKSLDENSPVCAKIADFGLSQQSVYS----VS--------GLLGNFQWMAPETIGVEDESYTEKVDTYSFAMILFTILTGEI------PFDE
||.|.|. . .     .. .||.|||||  .  .    ..        . .|.|.||||| .  . . |.||.| |||...|  |.|..|      |...
DLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQG

YSFGKMQFINLIRE--ENLRPTLPFDCDPRLSNLIQLCWSTNPKKRPSFTFIIKEL
...   | . ....  ||.||..| .| .....||| ||  .| .||||. ||..|
MDQ--EQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase QkgA_C2d.AA Dicty4 1298-1531 35 5.7e-60 198.76 In-house 31-277 (277) Show / Hide 
Range on Protein: 1298-1531
Range on HMM: 31-277/277
Sequence Identity: 35% (91 aa)

NNNNEDEFIEKFQEFQHEVFIMSNLNHPNIVKLYGLMH----NPPRM--VMEYVEHGDLYHLCQD----KERYASLGWTLKLR---LMIDIAKGIGYMQN
||.|.. . .  .|| .|| ||... ||||....|       .|..|  |.||.  |.|| |  |    .    .| |.| .|   ...|.|.|. .  .
NNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHC

QNPPIVHRDLRSPNIFLKSLDENSPVCAKIADFGLSQ----QSVYSV--SGLLGNFQWMAPETIGVEDESYTEKVDTYSFAMILFTILTGEIPFD-EYSF
 || |.|||| | |.     |.|  |  |..||||||     .  .   ..  |   |||||      ..|.||.| |||...|. |||...|.  ... 
CNPVIIHRDLKSHNLL---VDKNWRV--KVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVM--MHQPYNEKADVYSFGIVLWEILTRQEPYQKHHM-

GKMQFINLIREENLRPTLPFDCDPRLSNLIQLCWSTNPKKRPSFTFIIKE-LLEI
  |||.... .. ||| .| .|.|... ||| ||...|..||||  ||.. .|| 
PYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase QkgA_C2d.AA MLK 1302-1528 29 1.1e-52 181.09 In-house 45-291 (291) Show / Hide 
Range on Protein: 1302-1528
Range on HMM: 45-291/291
Sequence Identity: 29% (74 aa)

EDEFIEKFQEFQHEVFIMSNLN-HPNIVKLYGLMHNPPR---MVMEYVEHGDLYHLCQDKE-----------RYASLGWTLKLRLMIDIAKGIGYMQNQN
... ...|...  .. |.| .| ||.|...||  ..||     ||||.|.| ||... ...           ...     .... . ..|.|. |  .. 
TYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMA

P-PIVHRDLRSPNIFLKSLDENSPVC---AKIADFGLSQ-QSVY-S-VSGLLGNFQWMAPETIG-VEDESYTEKVDTYSFAMILFTILTGEIPFD-EYSF
| ||.|||| |.|| .    .. . .   .||.|||.|   .   .   .  |.. ||||| |   . | |.||.| .|....|  .||.|.|.. .|. 
PKPIIHRDLKSHNILIDE-ICH-DMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYD-

GKMQFINLIREENLRPTLPFDCDPRLSNLIQLCWSTNPKKRPSFTFIIKEL
  |. .  . ...|||..| .|......|.. ||...|.|||||  |...|
-PMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase QkgA_C2d.AA Pkinase_Tyr 1242-1528 27 5.8e-45 152.9 Pfam 1-270 (270) Show / Hide 
Range on Protein: 1242-1528
Range on HMM: 1-270/270
Sequence Identity: 27% (86 aa)

ILYERQIGEGGFGLIHKGKLI----SNKSDIAIKSLILCNSNNNNNSNNNNNSNNSNNFKNNNNEDEFIEK---FQEFQHEVFIMSNL-NHPNIVKLYGL
|   ...||| || ..||..     ..| . |.|.|                             .   ..    ..| .|. ||..| .|||||.||| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-K---------------------------EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGV

MH---NP--PRMVMEYVEHGDLYHLCQDK-ERYASLGWTLKLRLMIDIAKGIGYMQNQNPPIVHRDLRSPNIFLKSLDENSPVCAKIADFGLSQQS----
      |  . .||||..||||..  ... |   .|    .|   ..||||  |  ..|  ..||||.  |. ...    .  ..||.||||.       
CTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTE----NN-VVKICDFGLARDIYNDD

VY-SVSG-LLGNFQWMAPETIGVEDESYTEKVDTYSFAMILFTILT-GEIP-FDEYSFGKMQFINLIREENLRPTLPFDCDPRLSNLIQLCWSTNPKKRP
 |  ..|       ||||| |   .  .|.| | .||   .. |.| ||.| . .      .....| |.. |   | .| . . .|...||  .|..||
YYYRKRGGGKLPIKWMAPECI--NYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGM--SNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRP

SFTFIIKEL
.|. |. .|
TFSEIHEQL
Kinase QkgA_C2d.AA Dicty4-Unclassified 1299-1528 33 6.8e-45 151.68 In-house 31-263 (263) Show / Hide 
Range on Protein: 1299-1528
Range on HMM: 31-263/263
Sequence Identity: 33% (81 aa)

NNNEDEFI-EKFQEFQHEVFIMSNLNHPNIVKLYGLMHNP------PRMVMEYVEHGDLYHLCQ----DKERYASLGWTLKLRLMIDIAKGIGYMQNQNP
| | . |  |  |.|  || |.  . ||| ||.||   ||         |||    | |  .      ....  .|  || ..  .|||.|. ..   | 
NENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRN-

PIVHRDLRSPNIFLKSLDENSPVCAKIADFGLSQ--QSVYSVSGLLGNFQWMAPETIGVEDESYTEKVDTYSFAMILFTILTGEIPFDEYSFGKMQFINL
 ..|||..| ||    .| .    .||||||.|      .      |   | .||      |||. | | ||.||.|.  .||. |. |     |    .
-FIHRDIKSSNIL---MDKH--FNIKIADFGISRVIDFNFNMTTIAGTPKWESPECL--MHESYNQKSDVYSYAMMLYELATGDEPYQEIQ-SIMNAARS

IREENLRPTLPFDCDPRLSNLIQLCWSTNPKKRPSFTFIIKEL
. .  ||| .|  ||. .. ||  ||.  |.|||..  ||. |
VCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase QkgA_C2d.AA TK 1242-1528 16 7.3e-45 147.87 In-house 1-486 (486) Show / Hide 
Range on Protein: 1242-1528
Range on HMM: 1-486/486
Sequence Identity: 16% (86 aa)

ILYERQIGEGGFG---LIHKGKLISNK-------------------------SDIAIKSLILCNSNNNNN-----------SNNNNNSNNSNNFKNNNNE
| .....||| ||    ..||.... .                          . |.| | . .... .                               
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGG------------------

DEFIEKFQEFQHEVFIMSN--LNHPNIVKLYG--------------LMHNPPRMVMEYVEHGD----LYHLCQDKERYAS--------------------
    |.| |. .|  .|..  ..|||||.|||              .   |. .||||..|||    | .  ... ....                    
----EDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHH

-----------------------------------------------------LGWTLKLRLMIDIAKGIGYMQNQNP----PIVHRDLRSPNIFLKSLD
                                                     |    .|  . .||.|  |.  .|      .|||||   |. . . .
CMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENN

E------NSPVCAKIADFGLS------------QQSVYSVSGLLGN-------------------------FQWMAPETIG--VEDES-----YTEKVDT
       ... ..||||||||            . . | ...  |                          . |||||..   |. |.     .|.| | 
VCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDV

YSFAMILFTILT-G-EIPFDEYSFGK-------MQFINLIREE-------------NLRPTLPFDCD--------------PRLSNLIQLCWSTNPKKRP
.||   .. |.| | | .  . |  .        ......|..              .|.  | .|               . .  |.| ||. .|..||
WSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRP

SFTFIIKEL
.|. . ..|
TFSQLHEQL
Kinase QkgA_C2d.AA S_TKc 1242-1529 23 1.8e-44 154.98 SMART 1-231 (231) Show / Hide 
Range on Protein: 1242-1529
Range on HMM: 1-231/231
Sequence Identity: 23% (70 aa)

ILYERQIGEGGFGLIHKGKLISNKSDIAIKSLILCNSNNNNNSNNNNNSNNSNNFKNNNNEDEFIEKFQEFQHEVFIMSNLNHPNIVKLYGLMH-NPPRM
    |.||.|.||  .|.. .. .   ||| .                                    . .. |. |... .||||||||. .. .   |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------------------------------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYM

VMEYVEH--GDLYHLCQDKER---YASLGWTLKLRLMIDIAKGIGYMQNQNPPIVHRDLRSPNIFLKSLDENSPVCAKIADFGLSQQSVYSVSGLLGNFQ
||||...  |||... ... |   .  .      ..|  |.... |. ...  |.||||   ||.| .       . ||.||||. |     . . |   
VMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHG--IIHRDLKPENILLDE-------HIKICDFGLARQL----TTFCGTPW

WMAPETIGVEDESYTE-KVDTYSFAMILFTILTGEIPFDEYSFGKMQFINLIREENLRPTLPFDCDPRLSNLIQLCWSTNPKKRPSFTFIIK--------
.|||| .     .|.  |.| .|.  ||.  |.|. ||.      .. ...|.            .| . ..|. |.  .|.|||.   . .        
YMAPEVL-----GYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCH

ELL
. .
PWF
Kinase QkgA_C2d.AA DRK 1299-1530 34 7.3e-44 146.46 In-house 32-258 (258) Show / Hide 
Range on Protein: 1299-1530
Range on HMM: 32-258/258
Sequence Identity: 34% (83 aa)

NNNED-EFIEKFQEFQHEVFIMSNLNHPNIVKLYGLMHNPPRM--VMEYVEHGDLYHLCQDKERYASLGWTLKLRLMIDIAKGIGYMQNQNPPIVHRDLR
| |.. | .   .||. |. .|..| ||||.   |   |||    .|||   | ||    |     .. | | ...|.|.|||. |  . || |.|||| 
NHNINDENF--LNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDES--IEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLK

SPNIFLKSLDENSPVCAKIADFGLSQ-----QSVYSVSGLLGNFQWMAPETIGVEDESYTEKVDTYSFAMILFTILTGEIPFDEYSFGK--MQFINLIRE
| |      ||.  |  |.||||||      ..        |   | |||     .. |||| | |||| .|  ..| ..|.    ||.  .| .  .  
SHNLL---VDEHWQV--KVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVL--RNQRYTEKADVYSFAIVLWECVTRQDPY----FGMPTFQVVFSVGR

ENLRPTLPFDCDPRLSNLIQLCWSTNPKKRPSFTFIIKELLE
. .||  |  | |    |.. ||...|  |||.  ... |  
HGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase QkgA_C2d.AA CZAK 1312-1528 39 1.9e-41 144.04 In-house 47-279 (279) Show / Hide 
Range on Protein: 1312-1528
Range on HMM: 47-279/279
Sequence Identity: 39% (94 aa)

FQHEVFIMSNLNHPNIVKLYGL--MHN--PPRMVMEYVEHGDLYHLCQDKERYASLGWTLKLRLMIDIAKGIGYMQN-QNP-PIVHRDLRSPNIFL-KSL
|| || ||| | |||.|   |     .      |||. . | |  |  |.  |      |.. . ||||.|  |      | ||.|||| | || |  |.
FQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYHKQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSY

DENSPV-------CAKIADFGLS---QQSVYSVSGLLGNFQWMAPET-IGVEDESYTEKVDTYSFAMILFTILTGEIPFDEYSFGKMQFINLIREENLRP
.   ||        .||.|||||              |   |||||  .|   |.|||||| |||.|||. |.|.. |  .    || .  |   || ||
TPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKG---ENYTEKVDVYSFGMILWCIITCDQPYQNMQPMKMAH--LAAYENYRP

TLPFDCDPRLS---NLIQLCWSTNPKKRPSFTFIIKEL
 .|   ||       ||  ||  ||  |||| .|.  |
PMPQPMDPMWKNLGELIEMCWNKNPDERPSFKQILQHL
Kinase QkgA_C2d.AA TyrKc 1242-1528 24 3e-41 144.28 SMART 1-280 (280) Show / Hide 
Range on Protein: 1242-1528
Range on HMM: 1-280/280
Sequence Identity: 24% (80 aa)

ILYERQIGEGGFGLIHKGKLISNKSDIAIKSLILCNSNNNNNSNNNNNSNNSNNFKNNNNEDEFIEKFQEFQHEVFIMSNL--NHPNIVKLYGLMH----
|  ....||| || ..||...    . |.|.|  .                                 ..| .|  ||..|  .|||||.|||       
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------------------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGR

-----NPPRMVMEYVEHGDLYHLCQDKERYASLGWTLKLRLMIDIAKGIGYMQNQNPPIVHRDLRSPNIFLKSLDENSPVCAKIADFGLSQQS-------
      |. .||||..|||| .  .....   | .  .|  ...||.|  |   .  ...||||   |. ...       ..||.|||||          
NFMYIEPLMIVMEYMPHGDLKDYLRKHRPK--LCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQG

----VYSVS---GLL--GNFQWMAPETIGVEDESYTEKVDTYSFAMILFTILT-GEIPFDE---YSFGKMQFINLIR--EENLRPTLPFD--------CD
    .|...   |        |||||.|   .  .|.| | .||   .. |.| |. |  .       .|  . .|.  ..  |.  | .        | 
ESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ---MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCP

PRLSNLIQLCWSTNPKKRPSFTFIIKEL
. . .... ||  .|..||.|. |....
DEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase QkgA_C2d.AA TKL-ciliate2 1311-1529 34 1.1e-37 122.99 In-house 42-273 (273) Show / Hide 
Range on Protein: 1311-1529
Range on HMM: 42-273/273
Sequence Identity: 34% (84 aa)

EFQHEVFIMSNLNHPNIVKLYGLMHNPPR--MVMEYVEHGDLYHLCQDKERYASLGWTLKLRLMIDIAKGIGYMQNQNPPIVHRDLR-------------
.|  |   |  | |||||   |   . |   ..|||  .| |. | |...    | |  . |. .|||.|. |.   ||||.||||.             
DFVNECHAMEALRHPNIVMFLGACTKIPNFCIIMEYCQRGSLWSLLQNQD--VRLTWEDRRRIALDIARGVHYLHSSNPPIIHRDLKRQIKHKEKNLINI

-------SPNIFLKSLDENSPVCAKIADFGLSQQS--VYSVSGLLGNFQWMAPETIGVEDESYTEKVDTYSFAMILFTILTGEIPFDEYSFGKMQFINLI
       | |. .   |.|  .  |..|||          .   .| .|||||| |  .   |||| | .|...||. |   | |. . . |     . .
ITLIKINSLNVLV---DDN--FRCKLTDFGWTRVKPQDNYMTNKIGTYQWMAPEVI--KAFYYTEKADVFSYSIILWEIASREPPYRNKK-GDVVAEKVM

REENLRPTLPFDCDPRLSNLIQLCWSTNPKKRPSFTFIIKELL
. .|||||.| .| |....|.| ||  |   ||||  ||||| 
C-NNLRPTIPKNCPPQFADLMQRCWDNNQNLRPSFNEIIKELE
Kinase QkgA_C2d.AA Pkinase 1242-1528 24 7.2e-34 120.83 Pfam 1-293 (293) Show / Hide 
Range on Protein: 1242-1528
Range on HMM: 1-293/293
Sequence Identity: 24% (78 aa)

ILYERQIGEGGFGLIHKGKLISNKSDIAIKSLILCNSNNNNNSNNNNNSNNSNNFKNNNNEDEFIEKFQEFQHEVFIMSNLNHPNIVKLYGLMHNPPRMV
.  .|.||.|.||   |.. ...    |.| . ... . . . .. .                          |. || .|||||||.||. ....... 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL------------------------SEIQIMKRLNHPNIVRLYDWFEDKDHIY

--MEYVEHG----DLYHLCQ--DKERYASLGWTLKLRLMIDIAKGIGYMQNQNPPIVHRDLRSPNIFLKSLDENSPVCAKIADFGLS----QQSVYSVSG
  |||.|.|    ||... .  .. ..  . .    . |  |..|. |. ..   |.|||| . ||.... ..... | ||.||||.      .    ..
MVMEYCEGGLYVMDLFDYISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFDY-NNS-MTT

LLGNFQWMAPETIGVEDESYTEKVDTYSFAMILFTILTGEIPFDEY----SFGKMQFINLIREENLRPTLPFDCD-------------------PRLSNL
. |   .|||| |  ... |. ||| .|.  ||.  |.|. ||..     .  .|| |..|..  |.   | .|.                   . .  .
FCGTPWYMAPEVIR-GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDF

IQLCWSTNPKKRPSFTFIIKE--L
|  |.  .|||||... | .   .
IKWCLCKDPKKRPTAEQILQHPWF
Kinase QkgA_C2d.AA TKL-ciliate2 1242-1260 42 0.014374 3.73 In-house 1-19 (273) Show / Hide 
Range on Protein: 1242-1260
Range on HMM: 1-19/273
Sequence Identity: 42% (8 aa)

ILYERQIGEGGFGLIHKGK
.  . .| |||.|.| | |
LEIQNKITEGGYGIIYKAK
Kinase QkgA_C2d.AA MLK 1242-1264 34 0.022684 4.19 In-house 1-23 (291) Show / Hide 
Range on Protein: 1242-1264
Range on HMM: 1-23/291
Sequence Identity: 34% (8 aa)

ILYERQIGEGGFGLIHKGKLISN
|. .. ||.|.||  .||.   .
IQFHEWIGSGSFGKVWKGRWRNK
Kinase QkgA_C2d.AA Dicty4 1242-1260 47 0.084569 1.98 In-house 1-19 (277) Show / Hide 
Range on Protein: 1242-1260
Range on HMM: 1-19/277
Sequence Identity: 47% (9 aa)

ILYERQIGEGGFGLIHKGK
|  |  ||.|.||  .||.
INIEQRIGKGSFGEVYKGT