Gene Phg2 (Slime mold)

Phg2

Species: Slime mold
Alias: DdisK189, Phg2, DDB0229845
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: ARK

Sequence

Name Sequence Type Origin Length Description Download
Phg2.AA Protein None 1387 None Fasta, JSON
Phg2.kin_dom Protein Kinase Domain None 262 None Fasta, JSON

Protein domain

Protein domains of Phg2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Med15 Phg2.AA Med15 22-462 5 5.5e-05 16.55 Pfam 419-462 (945) Show / Hide 
Range on Protein: 22-462
Range on HMM: 419-462/945
Sequence Identity: 5% (25 aa)

QLQIQQRQLQLQQQEEQERLQQQQQQQQQQQDQQQHKLEEGSRRRSLSDVVGGVNISNKETPKRAFRIYWANDNHMYWTLLLDSTNTVGDVSEGLKDKVP
. ...|.. |.|||  | . |||.|.|.||| |||                                                                 
AMNMRQHCDQQQQQQQQQQQQQQHQAQHQQQQQQQ-----------------------------------------------------------------

SSGTQCYLYKRTKANFGRWKDRRLSNEDSVWDIVDRRRKNHKSDPIFVLKRKKSTFSISQKKSPQNESDTSPLSSSGEFLNPYTNPTGSNNIVPSNAGHS
                                                                                                    
----------------------------------------------------------------------------------------------------

RNTSSNSNNSANTSSNNLLAHHQFNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNSSNSNSNNSSNTTTTTTTTTTTTTTSTSTNSINT
                                                                                                    
----------------------------------------------------------------------------------------------------

SNNNNNNNSGSNINPSSFISPMSSLVSLSLSSSPASSAPHSPTLSSQPSSPHTITPITTSPPPPQRNNSSKSLKSTMEMEPPAEYISLLSNNPPPTNGSG
                                                                                                    
----------------------------------------------------------------------------------------------------

SRPPSGSFIPGSIVNGSRSSASDLIGFKPPVCQQQQQQQQQ
                                |||||.|||
--------------------------------QQQQQHQQQ
Kinase Phg2.AA ARK 807-1068 52 2.5e-200 671.78 In-house 1-280 (280) Show / Hide 
Range on Protein: 807-1068
Range on HMM: 1-280/280
Sequence Identity: 52% (148 aa)

LEYIKRIGSGTYSKVYKGKYRDKFVAIKTMRGSNMTTEQIESFKKECDILSTIQSPLLISFYGSCIEES----QLSMVVEYCSKGTLHKVLNNPLLDFDW
|||...||||...||||||||.|.||||..........|||.||||..|.|.|.||....|||.|||..    .|.||.||||.|.|....||...||.|
LEYTCKIGSGSSCKVYKGKYRGKEVAIKVLKSIMTDSMQIEEFKKEFQIMSSIRSPHVVYFYGACIEPEPQKQKLCMVMEYCSRGSLYHIMNNNKMDFGW

DKWFKWMTEVVEGVRYLHSMNPPMVHRDLKTLNILISSDWTAKLCDFGLTRTMTMTNVSTLGMLRGTMAYTAPEIYD-----------GLLFNTKSDVYS
|..||||...|.|...||...|..||||||.||.|....||.|.|||||.|..||.|..|||..|||.||.|||.|.           |....|||||||
DRFFKWMMQMVRGINCLHNWTPQIVHRDLKSLNLLVNENWTCKVCDFGLSRFNTMSNQETLGKMRGTFAYCAPEVYYFQDIDDDYVSNGKHYTTKSDVYS

LGVIMWEAIQRCISGVYLRPFHEH-PIS--MDIQIIILTSKNKVRPKISENCPEQLKTLITRCWDENPDKRPNCDEILEI
.|.||||...|||.|.|.||..|. .|.  .|.||.|.||||..||.|..|||||||.||..|||..||.||.|.||.|.
MGIIMWEMVYRCINGCYMRPYSEYKHIKNAFDFQILIQTSKNNLRPTIPQNCPEQLKNLIQCCWDQDPDNRPSCEEIMEE
Kinase Phg2.AA TKL 813-1069 25 1.7e-96 326.86 In-house 1-364 (364) Show / Hide 
Range on Protein: 813-1069
Range on HMM: 1-364/364
Sequence Identity: 25% (98 aa)

IGSGTYSKVYKGKYRD----------KFVAIKTMRGSNM------------------------TTEQIESFKKECD-ILSTIQSPLLISFYGSCIEESQ-
||||....|||||.|           | ||.|...  |.                        ...... |..|   ..| .. | ...|.|.|..... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LSMVVEYCSKGTLHKVLNNPLLDFDWDKWFKWMTEVVEGVRYLHSMN------PPMVHRDLKTLNILISSDWT--------------A
            | .| |||..|.|. .|.       |.. ..|. ..  |. ||||||      ||..|||||. |||. ..||              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KLCDFGLTRTMTM------------------TNVSTLGMLRGTMAYTAPEIYDGL----------------LFNTKSDVYSLGVIMWEAIQRCISGVYLR
|.||||| |.|..                  .| .|... .|| .. |||. .|                  ...|.|||| |...|| . ||.      
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR------

PFHEHPISMDI------QIIILTSKNKVRPKIS------------ENCPEQLKTLITRCWDENPDKRPNCDEILEIL
|....| .. |      ..... .... || |             ..||...| |...|||..|.|||...|||..|
PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase Phg2.AA TKL-Unique 809-1069 29 1.1e-80 274.32 In-house 1-290 (290) Show / Hide 
Range on Protein: 809-1069
Range on HMM: 1-290/290
Sequence Identity: 29% (85 aa)

YIKRIGSGTYSKVYKGKYRDKFVAIKTMR-GSNMTTEQIESFKKECDILSTIQ-SPLLISFYGSCI----EESQLSMVVEYCSKGTLHKVLN--------
 .. ||.|.|..|||||.| . ||||.    .    | .. |..|  ...... .| .  ..| |.     ......|.|||. |.|..||.        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-NPLLDFDWDKWFKWMTEVVEGVRYLHSMNPPMVHRDLKTLNILISSD-----WTAKLCDFGLTRTMTMTNVSTLGML--------RGTMAYTAPEIYDG
 |. ..... .  |    .. |  |||. .||. |||||..|.|....     | .|.||||| .. .  | .|....         |.  . |||.  .
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--LLFNTKSDVYSLGVIMWEAIQRCISGVYLRPFHEHPISMDIQIIILTSKNKVRPKISENCPEQLKTLITRCWDENPDKRPNCDEILEIL
   ....|||||| |...|| . |.|   | .|...     .....  . . . ||.|...||.... ||..||. .|..||. |||.. |
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYM-EENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase Phg2.AA MLK 807-1069 31 9.3e-60 204.85 In-house 1-291 (291) Show / Hide 
Range on Protein: 807-1069
Range on HMM: 1-291/291
Sequence Identity: 31% (95 aa)

LEYIKRIGSGTYSKVYKGKYRDKF-----VAIKTMR----GSNMTTEQIESFKKECDILSTIQSPL----LISFYGSCIEE-SQLSMVVEYCSKGTLHKV
..  . ||||.. ||.||..| |      ||.|  |     .  | .... |..|| .|. .. |      | ||| |... ...  | |||..| |. |
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

L--NNPLLD-----------FDWDKWFKWMTEVVEGVRYLHSMNP-PMVHRDLKTLNILISS------DWTAKLCDFGLTRTMTMTNVSTLGMLRGTMAY
|  ...  .            | |  ..|.. . .|. ||||| | | .|||||  ||||.       . |.| ||||. | .. .  ..    .|| |.
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAW

TAPEIY---DGLLFNTKSDVYSLGVIMWEAIQRCISGVYLRPFHEHPISMD-IQIIILTSKNKVRPKISENCPEQLKTLITRCWDENPDKRPNCDEILEI
 |||.     .  .. |.||.| ||..|| . | .      |..     .| ..|..    |. || |  .||| .| |...||...| |||. ..|...
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREV------PYK---QHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQH

L
|
L
Kinase Phg2.AA LRRK 807-1071 24 5.9e-55 188.9 In-house 1-351 (351) Show / Hide 
Range on Protein: 807-1071
Range on HMM: 1-351/351
Sequence Identity: 24% (91 aa)

LEYIKRIGSGTYS-KVYKGKYRD----------------------------KFVAIKTMRG--------------------------------SNMTTEQ
|.. . ||.|..  .||..|.|.                            . ||||..                                  . .... 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

IESFKKECDILSTIQSPLLISFYGSCIEESQLSMVVEYCSKGTLHKVLNNPL---L-----DFDWDKWFKWMTEVVEGVRYLHSMNPPMVHRDLKTLNIL
  .| .|. |.|. . | ..| .| ||.   | || || . |.|...| |.    .     ...|    | .... .|..|||| ||| .|||||. |||
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNIL

I-SS-----------DWTAKLCDFGLTRTMTMTNVST--LGMLRGTMAYTAPEIYDG---LLFNTKSDVYSLGVIMWEAIQRCISGVYL-RPFHEHP---
. ||           . .||..|||..| |  . . .  .  . |.  . ||||  .     ...|.|.|| |.|.||    ....  . .|| ||.   
LWSSPQNHSPNYPNAHVCAKIADFGISR-MF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWE----LLTR--QHHPFDEHDFFD

----ISMDIQIIILTSKNKVRPKISEN-CPE-----QLKTLITRCWDENPDKRPNCDEILEILLT
    .... ..||    .. ||.|... ||.      ...||. ||...|.|||   .|...| .
HMQWMEQIEDKII----EGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase Phg2.AA Dicty4 807-998 30 6.7e-54 178.23 In-house 1-209 (277) Show / Hide 
Range on Protein: 807-998
Range on HMM: 1-209/277
Sequence Identity: 30% (65 aa)

LEYIKRIGSGTYSKVYKGKYRDKFVAIKTM--RGSNMTTEQIESFKKECDILSTIQSPLLISFYGSCI----EESQLSMVVEYCSKGTLHKVLNN-----
.   .|||.| ...||||. | | ||.| .  .  |   . ...|.|| .|.. |. | .. |.|.|.    . . .. | ||..||.|...|..     
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

-PLLDFDWDKWFK---WMTEVVEGVRYLHSMNPPMVHRDLKTLNILISSDWTAKLCDFGLTR---TMTMTNVSTLGMLRGTMAYTAPEIYDGLLFNTKSD
 .    ||    .    .  .. |. .||. ||  .|||||. |.|.. .|..| ||||| .   . .. .  . ..  || ...|||.  .  .| |.|
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTAC-GTPCWMAPEVMMHQPYNEKAD

VYSLGVIMWE
||| | . ||
VYSFGIVLWE
Kinase Phg2.AA Pkinase 807-1069 24 5.5e-52 183.82 Pfam 1-293 (293) Show / Hide 
Range on Protein: 807-1069
Range on HMM: 1-293/293
Sequence Identity: 24% (74 aa)

LEYIKRIGSGTYSKVYKGKYRDKF--VAIKTMRGSNMTTEQIESFKK--ECDILSTIQSPLLISFYGSCIEESQLSMVVEYCSKG----TLHKVLN----
.. ...||||....|||.. ..    ||.|... ..   .. ..  .  |. |.  ...|  . .|... ... . || ||| .|     |. ..     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NPLLDFDWDKWFKWMTEVVEGVRYLHSMNPPMVHRDLKTLNILISSDWTA----KLCDFGLTRTMTMTNVSTLGMLRGTMAYTAPEIYD-GLLFNTKSDV
.... |...   ..|.....|. |.|||    .|||||  ||||... .     |.||||| . .   | | .  . ||  | |||.   |    .|.|.
GCFY-FSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

YSLGVIMWEAIQRCISGVYLRPFHEH----PISMDIQIIILTSKNKVRPKISENCP-------------------EQLKTLITRCWDENPDKRPNCDEIL
.|.|.|..| . .        || .|    .   ..|.| .. . ...  ... |.                   | .| .|..|.. .| |||....||
WSCGCILYEMLCGR------PPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL

EI--L
.   .
QHPWF
Kinase Phg2.AA S_TKc 807-1070 25 6.8e-48 166.34 SMART 1-231 (231) Show / Hide 
Range on Protein: 807-1070
Range on HMM: 1-231/231
Sequence Identity: 25% (71 aa)

LEYIKRIGSGTYSKVYKGKYRD--KFVAIKTMRGSNMTTEQIESFKKECDILSTIQSPLLISFYGSCIEESQLSMVVEYCSK--GTLHKVLNNPLLD---
 | .. ||.|...||||.. ..  . |||| ..         |....| .||.  . | .. .|... . . | || |||.   |.|.... .       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FDWDKWFKWMTEVVEGVRYLHSMNPPMVHRDLKTLNILISSDWTAKLCDFGLTRTMTMTNVSTLGMLRGTMAYTAPEIYDGLLFNT-KSDVYSLGVIM
  |.     ..| ...... |.||..   .|||||  |||...  . |.||||| | .          . ||  | |||.     ... |.|..|.|.|.
FPFPE-HARFYMYQICCALEYCHSHG--IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

WEAIQRCISGVYLRPFHEHPISMDIQIIILTSKNKVRPKISENCPEQLKTLITRCWDENPDKRPNCDEILE--------ILL
.| . ..       ||.   . | ...|                ....| .| .|.. .|.||| . |.|.          .
YEMLCGYP------PFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Phg2.AA DRK 810-1071 29 6.6e-47 156.92 In-house 1-258 (258) Show / Hide 
Range on Protein: 810-1071
Range on HMM: 1-258/258
Sequence Identity: 29% (82 aa)

IK---RIGSGTYSKVYKGKYRDKFVAIKTMRGSNMT-TEQIESFKKECDILSTIQSPLLISFYGSCIEESQLSMVVEYCSKGTLHKVLNNPLLDFDWDKW
||   ||| | |  |. |  |   ||.| .   |    . .  |..| ....    |  . | |.| . .    . || ..| | ..| .. .  ||   
IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLM

FKWMTEVVEGVRYLHSMNPPMVHRDLKTLNILISSDWTAKLCDFGL-T-------RTMTMTNVSTLGMLRGTMAYTAPEIYDGLLFNTKSDVYSLGVIMW
 . |  .  |. |||. ||  .|||||. | |.   |  |  |||| |       .. .|| .       ||   ||||.     .  | |||| ... |
KQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMC-------GTPCWTAPEVLRNQRYTEKADVYSFAIVLW

EAIQRCISGVYLRPFHEHPISMDIQIIILTSKNKVRPKISENCPEQLKTLITRCWDENPDKRPNCDEILEILLT
| . | .      |.   |     |...   . . || . ..||     |...||.|.|  ||  .|.||.|  
ECVTRQD------PYFGMPT---FQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase Phg2.AA TyrKc 807-1069 25 2.6e-46 161.1 SMART 1-280 (280) Show / Hide 
Range on Protein: 807-1069
Range on HMM: 1-280/280
Sequence Identity: 25% (76 aa)

LEYIKRIGSGTYSKVYKGKYRDKFVAIKTMRGSNMTTEQIESFKKECDILSTI--QSPLLISFYGSCIEE-------SQLSMVVEYCSKGTLHKVLNNPL
.. .| .|.| . .||||...   ||.|... .      .| | .|  |.. .  . | .. .|| |...        .| .|.||...| |.. | .. 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

LDFDWDKWFKWMTEVVEGVRYLHSMNPPMVHRDLKTLNILISSDWTAKLCDFGLTRTMTMT--------NVSTLG--MLR--GTMAYTAPEIYDGLLFNT
 .. ...  .... . .| .||||.  . .|||| . |.|.... |.| .||||.|  .            .. .    .       .|||  .   |.|
PKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KSDVYSLGVIMWEAIQRCISGVYLRPFHEHPIS--MDIQIIILTSKNKVRPKISEN--------CPEQLKTLITRCWDENPDKRPNCDEILEIL
||||.| || |||   .. .       .. .|   |. | .|   |.  |... .|        ||. . .....||.|.|..||.  || |..
KSDVWSFGVCMWEIFTYGQQ------PYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase Phg2.AA Dicty4-Unclassified 807-1069 32 2.9e-46 156.41 In-house 1-263 (263) Show / Hide 
Range on Protein: 807-1069
Range on HMM: 1-263/263
Sequence Identity: 32% (90 aa)

LEYIKRIGSGTYSKVYKGKYRDKFVAIKTM-RGSNMTT-EQIESFKKECDILSTIQSPLLISFYGSCIEE----SQLSMVVEYCSKGTLHKVLN------
.   . || |  |||.||  . | ||.| .  ..     | |. |||| .||  || | |.  || ||      | .  | |   ||.|  | .      
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQ

NPLLDFDWDKWFKWMTEVVEGVRYLHSMNPPMVHRDLKTLNILISSDWTAKLCDFGLTR----TMTMTNVSTLGMLRGTMAYTAPEIYDGLLFNTKSDVY
.  .  |     |   ..  |  .||. |  ..|||.|  |||.  .  .|  |||. |    . .|| .       || . ..||.  .  .| |||||
QQPIKLDDTLIIKYAFDIAQGMQHLHTRN--FIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIA------GTPKWESPECLMHESYNQKSDVY

SLGVIMWEAIQRCISGVYLRPFHEHPISMDIQIIILTSKNKVRPKISENCPEQLKTLITRCWDENPDKRPNCDEILEIL
| .....|     . |    |. | .  |.. . .  .| | ||||..||.  .| ||  || . | |||  ..| . |
SYAMMLYE----LATGD--EPYQEIQSIMNAARSV-CDK-KLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase Phg2.AA STE 807-1068 19 5.5e-43 149.14 In-house 1-359 (359) Show / Hide 
Range on Protein: 807-1068
Range on HMM: 1-359/359
Sequence Identity: 19% (73 aa)

LEYIKRIGSGTYSKVYKGKYR-----------------DKFVAIKTMR---------------GSNMTTEQIESFKKECDILSTIQ--SPLLISFYGSCI
.| |..||.|.. .|||....                  ...||| |.                .|. .|......|| .|..  .  .|  . .||...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EE-------SQLSMVVEYCSKGTLHKVLNNPLLDFDW------------DKWFKWMT-EVVEG-VRYLHSMNPPMVHRDLKTLNILISSDWTAKLCDFGL
 |       ..| .. ||.. |.| .....    ..              .. .... ....|   ||||..   .|||.|  |||.     .||||||.
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL-----VKLCDFGV

TRTMTM---------------TNVSTLGMLRGTMAYTAPEIYDG------LLFNTKSDVYSLGVIMWEAIQRCISGVYLRPFHE-HPISMDIQIIILTSK
   .|                |...    . ||  . |||. ..         .||.|..|||  ..| .  .       |.|. || ..  .|.. . .
CGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKP------PWHDMHPMRAMFMIPFNYHM

N----------KVRPKISE-------------------NCPEQLKTLITRCWDENPDKRPNCDEILE-----I
           .  |.. .                   .. . .|  | .| . .|.|||. .. |.     |
QQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase Phg2.AA Pkinase_Tyr 807-998 28 2e-38 130.76 Pfam 98-303 (270) Show / Hide 
Range on Protein: 807-998
Range on HMM: 98-303/270
Sequence Identity: 28% (60 aa)

LEYIKRIGSGTYSKVYKGKYR------DKFVAIKTMRGSNMTTEQ--IESFKKECDILSTI-QSPLLISFYGSCI-EESQ--LSMVVEYCSKGTLHKVLN
.. .| .|.| . .||||...      .  ||.|...  . . ||  .|.| .|  |.... . | ....|| |. .. .  . .|.||. .| |.. | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

NP---LLDFDWDKWFKWMTEVVEGVRYLHSMNPPMVHRDLKTLNILISSDWTAKLCDFGLTRTMTMTNVS--TLGMLRGTMAYTAPEIYDGLLFNTKSDV
..      ..     .. ... .|  ||.|.|  ..|||| . |.|.... ..| |||||.|... .     . |  .     .|||      |.|||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDV

YSLGVIMWE
.| || |||
WSFGVLMWE
Kinase Phg2.AA TKL-ciliate2 807-1002 31 1.8e-37 122.25 In-house 1-214 (273) Show / Hide 
Range on Protein: 807-1002
Range on HMM: 1-214/273
Sequence Identity: 31% (68 aa)

LEYIKRIGSGTYSKVYKGKYRDKFVAIKTMRGSNMTTEQIESFKKECDILSTIQSPLLISFYGSCIEESQLSMVVEYCSKGTLHKVLNNPLLDFDWDKWF
||   .|  | |  .|| |.|.  ||.|  .      .||  |  ||. .  .  | .. | | | .    ....||| .| |  .| |      |.   
LEIQNKITEGGYGIIYKAKWREIVVAVKKFKMDHDNQQQIRDFVNECHAMEALRHPNIVMFLGACTKIPNFCIIMEYCQRGSLWSLLQNQDVRLTWEDRR

KWMTEVVEGVRYLHSMNPPMVHRDLK--------------------TLNILISSDWTAKLCDFGLTRTMTMTNVSTLGMLRGTMAYTAPEIYDGLLFNTK
.   ..  || |||| |||..|||||                     ||.|.      || ||| ||     |  |  .  ||  . |||.    ..  |
RIALDIARGVHYLHSSNPPIIHRDLKRQIKHKEKNLINIITLIKINSLNVLVDDNFRCKLTDFGWTRVKPQDNYMTNKI--GTYQWMAPEVIKAFYYTEK

SDVYSLGVIMWEAIQR
 ||.| ..|.||   |
ADVFSYSIILWEIASR
Kinase Phg2.AA Dicty4 1031-1071 41 1.2e-14 45.45 In-house 235-277 (277) Show / Hide 
Range on Protein: 1031-1071
Range on HMM: 235-277/277
Sequence Identity: 41% (18 aa)

KVRPKISENCPEQLKTLITRCWDENPDKRPNCDEILEI--LLT
| ||.|. .||  .|.||..|||..| .||   ||...  | .
KLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase Phg2.AA TKL-ciliate2 1029-1070 45 3.4e-10 29.65 In-house 232-273 (273) Show / Hide 
Range on Protein: 1029-1070
Range on HMM: 232-273/273
Sequence Identity: 45% (19 aa)

KNKVRPKISENCPEQLKTLITRCWDENPDKRPNCDEILEILL
.| .|| |  ||| |.  |. ||||.| . ||  .||.  | 
CNNLRPTIPKNCPPQFADLMQRCWDNNQNLRPSFNEIIKELE
Kinase Phg2.AA Pkinase_Tyr 1033-1069 40 5.9e-10 34.34 Pfam 234-270 (270) Show / Hide 
Range on Protein: 1033-1069
Range on HMM: 234-270/270
Sequence Identity: 40% (15 aa)

RPKISENCPEQLKTLITRCWDENPDKRPNCDEILEIL
| .. ||||. . .|...||...|..||   ||.|.|
RMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL