DDB0231199

Species: Slime mold
Alias: DDB0231199, DdisK206
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: Dicty4

Sequence

Name Sequence Type Origin Length Description Download
DDB0231199.AA Protein None 1634 None Fasta, JSON
DDB0231199.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of DDB0231199.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
MORN DDB0231199.AA MORN 61-82 27 0.002679 13.62 SMART 1-22 (22) Show / Hide
Range on Protein: 61-82
Range on HMM: 1-22/22
Sequence Identity: 27% (6 aa)

SIYSGQWNSDKKEGDGTLIILK
..| |.|  .|. | |...   
DRYEGEWHNGKRHGHGVYWWAN

MORN DDB0231199.AA MORN 38-60 26 0.070056 3.01 SMART 1-22 (22) Show / Hide
Range on Protein: 38-60
Range on HMM: 1-22/22
Sequence Identity: 26% (6 aa)

GFYKGNLNENKLKNGKGTFLFPN
  | |.  ..| . |.|.. ..|
DRYEGEWHNGK-RHGHGVYWWAN

MORN DDB0231199.AA MORN 63-79 35 0.143395 10.46 Pfam 1-17 (23) Show / Hide
Range on Protein: 63-79
Range on HMM: 1-17/23
Sequence Identity: 35% (6 aa)

YSGQWNSDKKEGDGTLI
|.|.|  .|..| |...
YEGEWKNGKMHGHGVYT

MORN DDB0231199.AA MORN 40-60 28 2.278031 6.1 Pfam 1-20 (23) Show / Hide
Range on Protein: 40-60
Range on HMM: 1-20/23
Sequence Identity: 28% (6 aa)

YKGNLNENKLKNGKGTFLFPN
| |.   | ...|.|.. .|.
YEGEW-KNGKMHGHGVYTWPD

MORN DDB0231199.AA MORN 169-191 39 0.001363 17.8 Pfam 1-23 (23) Show / Hide
Range on Protein: 169-191
Range on HMM: 1-23/23
Sequence Identity: 39% (9 aa)

YNGKWINGKANGIGCFHFSKDDS
| | | ||| .| |.....  | 
YEGEWKNGKMHGHGVYTWPDGDR

MORN DDB0231199.AA MORN 167-188 40 0.006477 10.75 SMART 1-22 (22) Show / Hide
Range on Protein: 167-188
Range on HMM: 1-22/22
Sequence Identity: 40% (9 aa)

DYYNGKWINGKANGIGCFHFSK
| | | | |||  | |..... 
DRYEGEWHNGKRHGHGVYWWAN

Kinase DDB0231199.AA Dicty4-Unclassified 1377-1629 63 3.6e-210 704.49 In-house 1-263 (263) Show / Hide
Range on Protein: 1377-1629
Range on HMM: 1-263/263
Sequence Identity: 63% (168 aa)

LQILQFLGEGALAEVHKGIWKGKEVAVKIFNEGSFSFR---LEDFLKEVAILGLISHPNLLKLKGACIAPRSHKSTFMIVTELMHKGTLLEVIN-----K
.||.||.|.|....||||.||||.||||.|||..|.||   ..||.|||.|||.|.||||.|..|.||.|||||||..||.|.||||.|.|||.     .
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQ

NKPLSLED--IIKYALSVAQGLAYLHSVDFIHRDIKAANILVDKNNNAKVGDFGLSRVIDNNFNMTAVAGTPKWESPECLMGEAYTSASDVYSYGMMLFE
..|..|.|  |||||...|||...||...|||||||..|||.||..|.|..|||.|||||.|||||..|||||||||||||.|.|...||||||.|||.|
QQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYE

LATGDEPFLEIQSIVELARSVCDKKLKPKISSSVPNFISSLIKDCLHNSPKKRPTMNQIIQKL
|||||||..|||||...|||||||||.|||.....||...|||.|.||.|.||||||||||.|
LATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL

Kinase DDB0231199.AA Dicty4 1377-1632 38 5.1e-160 537.19 In-house 1-277 (277) Show / Hide
Range on Protein: 1377-1632
Range on HMM: 1-277/277
Sequence Identity: 38% (107 aa)

LQILQFLGEGALAEVHKGIWKGKEVAVKIF---NEGSFSFRLEDFLKEVAILGLISHPNLLKLKGACIAPRSHKSTFMIVTELMHKGTLLEVINK-----
..| |..|.|...||.||.|.|||||||..   |.......|..|.|||.|.. |.|||.....|||.|||||.....||||.|.||.|......     
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

--NKPLSLEDIIK---YALSVAQGLAYLHS--VDFIHRDIKAANILVDKNNNAKVGDFGLSR----VIDNNFNMTAVAGTPKWESPECLMGEAYTSASDV
  ...|....|..   .|...|.|...||.  ...||||.|..|.|||||...||.|||||.    ..|...|.....|||.|..||..|...|....||
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADV

YSYGMMLFELATGDEPFL-EIQSIVELARSVCDKKLKPKISSSVPNFISSLIKDCLHNSPKKRPTMNQIIQK-LCNH
||.|..|.|..|..||.. .........|.||.|||.|.|....|.....||..|....|..||....|||. . .|
YSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase DDB0231199.AA TKL 1383-1629 24 2.2e-93 316.57 In-house 1-364 (364) Show / Hide
Range on Protein: 1383-1629
Range on HMM: 1-364/364
Sequence Identity: 24% (92 aa)

LGEGALAEVHKGIWKG----------KEVAVKIFNEGS--------------------------FSFRLEDFLKEVAILGLISHPNLLKLKGACIAPRS-
.|.|. .||.||.|.|          |.||||.|.. .                           |.  . . .|. ..  ..|||.....|.|..|.. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

--------HKSTFMIVTELMHKGTLLEVINKNKPLSLEDIIKYALSVAQGLAYLHSVD--------FIHRDIKAANILVDKNNN--------------AK
        ... ..||.|....|.||....      .. ... ||..|.|..|||| .         ||||.| .|||||.|..              .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

VGDFGLSRVIDNNFNMTA--------------------VAGTPKWESPECLMGE----------------AYTSASDVYSYGMMLFELATGDEPFLEI--
..||||||......||..                    . ||| | .||.|.|.                 |. ..||||.|..|.|..|. .|. ..  
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

QSIV------ELARSVCDKKLKPKIS------------SSVPNFISSLIKDCLHNSPKKRPTMNQIIQKL
 ...      | .  ||||.|.| |             ...|  ...|..|| .  |.|||....|...|
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase DDB0231199.AA TKL-Unique 1379-1629 29 2e-78 266.86 In-house 1-290 (290) Show / Hide
Range on Protein: 1379-1629
Range on HMM: 1-290/290
Sequence Identity: 29% (87 aa)

ILQFLGEGALAEVHKGIWKGKEVAVKIFN-EGSFSFR-LEDFLKEVAILGLIS-HPNLLKLKGACIAPRSHKSTFMIVTELMHKGTLLEVIN--------
..  .|||. ..| ||.|.|..||.|.|. . ..|.. ...| .|| ..  .  |||.... |.|.    . . . ||.| .  |.| .|..        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

--KNKPLSLEDIIKYALSVAQGLAYLHSVD--FIHRDIKAANILVDKN-----NNAKVGDFGLSRVIDNNFNMTAV----------AGTPKWESPECLMG
  .|..|... ..| |. .|||. |||. .   ||||.|  |.||| |     .|.|. |||||.. ... .||.            |.. | .|| |..
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--EAYTSASDVYSYGMMLFELATGDE------PFLEIQSI--VELARSVCDKKLKPKISSSVPNFISSLIKDCLHNSPKKRPTMNQIIQKL
  . |.  |||||.|..| |.||..       |. .. ..   |.....  ... |.|... |. .. ||..| |  | .||. ..|| .|
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYM-EENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL

Kinase DDB0231199.AA MLK 1377-1629 30 2.9e-69 236.4 In-house 1-291 (291) Show / Hide
Range on Protein: 1377-1629
Range on HMM: 1-291/291
Sequence Identity: 30% (91 aa)

LQILQFLGEGALAEVHKGIWKGKE-----VAVKIFN---EGSFSFR---LEDFLKEVAILGLISHPN----LLKLKGACIAPRSHKSTFMIVTELMHKGT
.|.....|.|.  .|.|| |..|.     ||||...   . . |      .|| .|. .|  .||||      ...|.|. | .|   | ||.| . .| 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCH---FCIVMEYCEGGS

LLEVINKNKP--------------LSLEDIIKYALSVAQGLAYLHSVDF---IHRDIKAANILVD------KNNNAKVGDFGLSRVIDNN-FNMTAVAGT
| .|.. ...               ... ... || .|.|..|||| .    ||||.|  |||.|      .. ..|. |||.|| . ..  ||.  |||
LYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGT

PKWESPECL---MGEAYTSASDVYSYGMMLFELATGDEPFLEIQSIVELARSVCDKKLKPKISSSVPNFISSLIKDCLHNSPKKRPTMNQIIQKL
. | .|| .    .| |. ..||.|.|..| |. |. .|. ....  . |  |  ..| | | |. |  ...|.|.| .  |.|||.. ||.|.|
YAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase DDB0231199.AA Pkinase_Tyr 1377-1629 32 2e-68 232.34 Pfam 1-270 (270) Show / Hide
Range on Protein: 1377-1629
Range on HMM: 1-270/270
Sequence Identity: 32% (90 aa)

LQILQFLGEGALAEVHKGIWK------GKEVAVKIFNEGSFSFR---LEDFLKEVAILGLI-SHPNLLKLKGACIAPRSHKST--FMIVTELMHKGTLLE
..... |||||  ||.||.||      . .||||. .| . . .   .|||..|..|.  . .|||...| |.|.   ...     .||.|.| .| ||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCT---DQGEPNQIYIVMEYMPHGDLLD

VINK----NKPLSLEDIIKYALSVAQGLAYLHSVDFIHRDIKAANILVDKNNNAKVGDFGLSRVIDNNFNMTAVAGT-----PKWESPECLMGEAYTSAS
   |    ..||...|...... .|.|..||.|  .||||. | |.||..|| .|..||||.| | |  .   ....      || .|||..   .|..|
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKS

DVYSYGMMLFELAT-GDEP-FLEIQSIVELARSVCDKKLKPKISSSVPNFISSLIKDCLHNSPKKRPTMNQIIQKL
||.|.|  ..|. | |..| . .. |  |. . . ..    ..    |  | .|.|.| |  |..|||. .|...|
DVWSFGVLMWEIFTYGEQPTYPGM-SNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase DDB0231199.AA TyrKc 1377-1629 30 2.9e-66 227.36 SMART 1-280 (280) Show / Hide
Range on Protein: 1377-1629
Range on HMM: 1-280/280
Sequence Identity: 30% (88 aa)

LQILQFLGEGALAEVHKGIWKGKEVAVKIFNEGSFSFRLEDFLKEVAILGLI--SHPNLLKLKGACIAP--RSHK---STFMIVTELMHKGTLLEVINKN
.. .. |||||  ||.||.||  .||||  .|..    .|||..|  |.  .  .|||...| |.|. .  .         |||.|.| .| |.. . |.
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHGDLKDYLRKH

KP-LSLEDIIKYALSVAQGLAYLHSVDFIHRDIKAANILVDKNNNAKVGDFGLSRVIDNN------FNMTAVA---GTP-----KWESPECLMGEAYTSA
.| |...| ..... .|.| .||||  .||||. | |.||..|. .|..|||||| |..         .  ..   |.      .| .|||..   .|..
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

SDVYSYGMMLFELAT-GDEPFLEI----QSIVELARSVCDKKLKPKISS--------SVPNFISSLIKDCLHNSPKKRPTMNQIIQKL
|||.|.| ...|. | |..|  ..     |  |. . | . .  |.  .          .   . ..|.| |  |..|||...|....
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF

Kinase DDB0231199.AA Pkinase 1377-1629 26 3.5e-65 227.64 Pfam 1-293 (293) Show / Hide
Range on Protein: 1377-1629
Range on HMM: 1-293/293
Sequence Identity: 26% (80 aa)

LQILQFLGEGALAEVHKGIWKGKE--VAVKIFNEGSFSFRLE--DFL-KEVAILGLISHPNLLKLKGACIAPRSHKSTFMIVTELMHKG----TLLEVIN
..|.. .|.|. ..| |...|| .  |||||..  . .   .  ...  |..|.  ..||| ..|....      |.   .|.|.. .|     | ..| 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----KDHIYMVMEYCEGGLYVMDLFDYIS

--KNKPL--SLEDIIKYALSVAQGLAYLHSVDFIHRDIKAANILVDKNNNA----KVGDFGLSRV--IDNNFNMTAVAGTPKWESPECLM-GEAYTSASD
  .....  | .....|.. ...||.|.||  .||||.| .|||.|.|..     |..||||...  . ||  || ..||| . .|| .. |. |....|
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

VYSYGMMLFELATGDEPFLEI------QSIVELARSVC-DKKLKPKISSSVP-----------------NFISSLIKDCLHNSPKKRPTMNQIIQK--L
..|.| .|.|...|  || .         .. ..|  . . .     ..|..                     ..||.||.  ||||||  || |   .
MWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase DDB0231199.AA TK 1377-1629 18 3.4e-64 213.82 In-house 1-486 (486) Show / Hide
Range on Protein: 1377-1629
Range on HMM: 1-486/486
Sequence Identity: 18% (89 aa)

LQILQFLGEGALA---EVHKGIWKGK---------------------------EVAVKIFNEG-SFSFR-LED-----------FLKEVAILGLIS----
..... ||||.     ||.||.|.|.                           .||||.  || . | .  .|           ||.|.... . .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNLLKLKGACIAPR--------SHKSTFMIVTELMHKGT----LLEVINKNKP---------------------------------------------
 |||...| |.|  ..        .|.  .|||.|.|..|     |..   |..|                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSLEDIIKYALSVAQGLAYLHSV------DFIHRDIKAANILVDKNNN-----------AKVGDFG---
                               |.... . ... .|.|..||||        |.|||. | |.||..||.           .|..|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSRVIDNNFNMTAVAGTPK---------------------------WESPECLMGEA---------YTSASDVYSYGMMLFELAT-GDEPFLEIQ
     |.| |... . ... .  .                           | .||||..           .|..|||.|.| ...|. | |.||. .  
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SI---------------------------------VELAR-SVCDK----KLKPKISSSVPNFISSLIKDCLHNSPKKRPTMNQIIQKL
|                                   ....   |      .  . ...  | ..  |...| |  |..|||. |. ..|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase DDB0231199.AA LRRK 1372-1631 24 4.9e-64 219.06 In-house 1-351 (351) Show / Hide
Range on Protein: 1372-1631
Range on HMM: 1-351/351
Sequence Identity: 24% (89 aa)

IEESELQILQFLGEGALA-EVHKGIWKG----------------------------KEVAVKIFNEG---------------------------------
... |.     .|.|. . .|....|.|                            ..||.|..| .                                 
LKIEEQ-----IGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHE

SFSFRLEDFLKEVAILGLISHPNLLKLKGACIAPRSHKSTFMIVTELMHKGTLLEVINKNK---------PLSLEDIIKYALSVAQGLAYLHSVD--FIH
...  .  | .||.|.    |||...||| || |      ...|.|..  |.| ... ..|          .|   ..| || .| |..|||| .  .||
DCCRAFREFRHEVWIMSHLNHPNIVSLKGFCIHP------LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIH

RDIKAANILV--DKNN----------NAKVGDFGLSR--VIDNNFNMTAVAGTPKWESPECLMGE---AYTSASDVYSYGMMLFELATGD-EPFLEIQSI
|| |  |||.   ..|          .||..|||.||   .. .     . |.| | .||.. ..    ||  .|.||.|| |.|| |..  || |... 
RDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFF

-----VELARSVCDKKLKPKISSS-VPN-----FISSLIKDCLHNSPKKRPTMNQIIQKLCN
      |. .    ..|.|.|...  |        ..||..| .. |||||...||...|  
DHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ

Kinase DDB0231199.AA S_TKc 1377-1627 27 7e-62 212.82 SMART 1-220 (231) Show / Hide
Range on Protein: 1377-1627
Range on HMM: 1-220/231
Sequence Identity: 27% (73 aa)

LQILQFLGEGALAEVHKGIWKG--KEVAVKIFNEGSFSFRLEDFLKEVAILGLISHPNLLKLKGACIAPRSHKSTFMIVTELMHK--GTLLEVINKNKP-
 .||. .|.|| ..|.|...|.  ..||.|| .        |....|..||    |||. ||....       . . .|.|..    |.|...| |... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LSLEDIIKYALSVAQGLAYLHSVDFIHRDIKAANILVDKNNNAKVGDFGLSRVIDNNFNMTAVAGTPKWESPECLMGEAYTS-ASDVYSYGMMLF
     ..  .. .|.  ....|.|.||  .||||.| .|||.|.  . |..||||.|..      | . ||| . .|| |    |.  ..|..| | .|.
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELATGDEPFLEIQSIVELARSVCDKKLKPKISSSVPNFISSLIKDCLHNSPKKRPTMNQIIQ
|...|  ||     . .. . ..            | ... .|. ||.  |.||||  .. |
EMLCGYPPFP---QMQMMFKKIG-----------SPEAKD-FIRKCLQKDPEKRPTA-EALQ

Kinase DDB0231199.AA Dicty5 1377-1633 32 6.2e-60 204.96 In-house 1-260 (260) Show / Hide
Range on Protein: 1377-1633
Range on HMM: 1-260/260
Sequence Identity: 32% (85 aa)

LQILQFLGEGALAEVHKGIWKGKEVAVKIFNEGS-FSFRLEDFLKEVAILGLIS--HPNLLKLKGACIAPRSHKSTFMIVTELMHKGTLLEVIN-KNK--
  . ..   ||   | .|| ||. ||.| .     . | ...| .||.|. ..   |||. .  ||    .  .    .|||. |.|.| .  | . |  
VSFHDWIASGASGRVYNGIYKGMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAH---QYNDKYPFHVTEYCHNGSLFNYLNDQRKTT

--PLSLEDIIKYALSVAQGLAYLHSVDFIHRDIKAANILVDKNNNAKVGDFGLSRVIDNNFNMTAVAGTPKWESPECLMGEAYTSASDVYSYGMMLFELA
  |..   ..  |. .||.. .|||.  ||||.|  |.|. .|  .|. ||| || .||  .||   ||. | ..|   |  |.   ||||.|  |.|. 
GQPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMF

TGDEPFLEIQSIVELARSVCDKKLKPKISSSVPNFISSLIKDCLHNSPKKRPTMNQIIQKLCNHK
| .||. .| .. . .  |  |   | |   .|  || ||| |    |..||.   |.. .    
TRKEPYDNINNW-NIPVMVM-KGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII

Kinase DDB0231199.AA UTK 1377-1629 26 6.5e-50 168.94 In-house 1-296 (296) Show / Hide
Range on Protein: 1377-1629
Range on HMM: 1-296/296
Sequence Identity: 26% (81 aa)

LQILQFLGEGALAEVHKGIWK------GK-EVAVKIFNEGSF-SFRLE---DFLKEVA---ILGLIS-HPNLLKLKGACIAPRSHKSTFMIVTELMHKGT
.|... ||.||  ||||. ..      ..  ||||  .....  .  |   ||..| .   ...  . |||.|.| | | .       .|||||.| .| 
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP----WMIVTEYMENGD

LLEVINKNKP--------LSLEDIIKYALSVAQGLAYLHSVDFIHRDIKAANILVDKN-------NNAKVGDFG---LSRVIDN-----------NFNMT
|. .  ...|        |.|.. ...|. .| |..||||  |.|||. | |.||...       . .|..|||   .|| . .            ....
LRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQ

-AVAGTPKWESPECLMGE-AYTSASDVYSYGMMLFELAT-GDEPFLEIQSIVELARSVCDKK-LKPKISSSVPNFISSLIKDCLHNSPKKRPTMNQIIQK
 . . . .| .||.|     .|..|||.|.|  ..|. | |  |. .. | .... .||..  . ..   ..|  .  | ..| | .| .||.. .. |.
HQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGM-SNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQ

L
.
M

Kinase DDB0231199.AA STE 1377-1630 20 2e-48 167.21 In-house 1-359 (359) Show / Hide
Range on Protein: 1377-1630
Range on HMM: 1-359/359
Sequence Identity: 20% (75 aa)

LQILQFLGEGALAEVHKGIWK-----------------GKEVAVKIFN----------------EGSFSFRLEDFLKEVAILGLIS--HPNLLKLKGACI
.......|.||  .|.|.. .                 |. .|.|. |                | ...  ....|||. |.   .  |||  |  |...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

AP---RSHKSTFMIVTELMHKGTLLEVIN-KNKPLSL------------EDII-KYALSVAQG-LAYLHSVDFIHRDIKAANILVDKNNNAKVGDFGLSR
      . ...  |. |.|  |.| ..|. | ...              |..| ... .. .| |.||||   ||||||.||||.     .|  |||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

-VIDNNF----------------NMTAVAGTPKWESPECLMG------EAYTSASDVYSYGMMLFELATGDEPF---LEIQSIVELARSV----------
 ..|..                 . . ..||| | .|| ...        |.  .|..| | .. |.|||  |.      . . . ...           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---CDK-KLKPKIS---------------SSVPNFISSLIKDCLHNSPKKRPTMNQIIQ---KLC
    .  .|....|               ...       |. ||   |.|||| .| ..   .  
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI