Gene DDB0229963 (Slime mold)
DDB0229963
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| DDB0229963.AA | Protein | None | 2165 | None | Fasta, JSON |
| DDB0229963.kin_dom | Protein Kinase Domain | None | 255 | None | Fasta, JSON |
Protein domains of DDB0229963.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| PX | DDB0229963.AA | PX | 645-737 | 22 | 5.1e-07 | 26.6 | Pfam | 1-103 (120) | Show / Hide |
Range on Protein: 645-737 Range on HMM: 1-103/120 Sequence Identity: 22% (24 aa) TAWDISIRIVGFF-----QIDDHIEYKLQVISNSN-----EWFVCRRYNNFLMLDKKLKSSGIIDKKDLGL-TLPPKK-LKV---ASNQVAKARQLPLQS . ... ...|... . ..| .|. .. |.| ||.| |||. |. | |.||. .. . .||||. .. . .... |. |.. DHFLQ-VHVVDPETHKHYGDKMHYYYVYEIHMNTNPFQKKEWHVWRRYSDFHWLHKQLKRHFP----MCIIPPLPPKHWFGRYNNFDEEFIEKRRQMLEQ YLVHLLSN || ..... YLQRVCQH |
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| PX | DDB0229963.AA | PX | 645-753 | 20 | 0.000119 | 17.36 | SMART | 1-142 (142) | Show / Hide |
Range on Protein: 645-753 Range on HMM: 1-142/142 Sequence Identity: 20% (29 aa) TAWDISIRIVGFF------QIDDHIEYKLQVISNSN----EWFVCRRYNNFLMLDKKLKSSGIIDKKDLGLTLPPKKLKV-------------------- ....| | .|.|| . ..| | .. ..| .| |.|||. |. |...|| ..| ....|| . |. DHIFI-ITVVEFFTHGKHYHDGKHYYYVYEIHTKTNNHVKMWTVYRRYSDFHWLHHQLKRHFPQEK--RMCIIPPLPPKHWFVRYRYWMEHMSMMWWYSF --ASNQVAKARQLPLQSYLVHLLSNYQGIF--YNNNIVAT--TNS . ... |.. |..|| .|... . | ....|.. ..| NNFDEDFIEKRRRGLERYLQRLCHHPEWINHYMVCEVVYEFFESS |
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| Kelch_1 | DDB0229963.AA | Kelch_1 | 1487-1505 | 42 | 0.05054 | 11.02 | Pfam | 1-19 (45) | Show / Hide |
Range on Protein: 1487-1505 Range on HMM: 1-19/45 Sequence Identity: 42% (8 aa) PRSSHSVTVYGSSLVLIGG ||..|.|.|.. . ||| PRCGHGVCVHNGKIYVIGG |
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| Kelch_2 | DDB0229963.AA | Kelch_2 | 1487-1505 | 36 | 0.151487 | 10.0 | Pfam | 1-19 (51) | Show / Hide |
Range on Protein: 1487-1505 Range on HMM: 1-19/51 Sequence Identity: 36% (7 aa) PRSSHSVTVYGSSLVLIGG ||..|...|.|. ....|| PRYCHASCVPGGKIYVFGG |
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| Kelch_2 | DDB0229963.AA | Kelch_2 | 1538-1585 | 29 | 0.001849 | 17.27 | Pfam | 1-51 (51) | Show / Hide |
Range on Protein: 1538-1585 Range on HMM: 1-51/51 Sequence Identity: 29% (15 aa) SIYNHDYCRIGNKFYLFGGY--VAGKLSNKLYVLTIMDDSTVHWSS-PRIS . |.| .| .|.| |.|||| .. . . .. ..|..| .|. ||. PRYCHASCVPGGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP |
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| Kelch_1 | DDB0229963.AA | Kelch_1 | 1538-1575 | 18 | 5.930471 | 3.6 | Pfam | 1-37 (45) | Show / Hide |
Range on Protein: 1538-1575 Range on HMM: 1-37/45 Sequence Identity: 18% (7 aa) SIYNHDYCRIGNKFYLFGGYVAGKLSNKLYVLTIMDDS ..| | ...| | .||. .|. ... .... PRCGHGVCVHNGKIYVIGGCDG-QYLNSVECYDPETNQ |
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| Kelch_2 | DDB0229963.AA | Kelch_2 | 1592-1637 | 29 | 1e-08 | 37.23 | Pfam | 1-51 (51) | Show / Hide |
Range on Protein: 1592-1637 Range on HMM: 1-51/51 Sequence Identity: 29% (15 aa) PRYGHTFTRYGNRFLLFGGY-----DGEQCLNDLYILEPETMCWSTVTNIK |||.|... .|.. ..|||| .. ..|.... ||| .|. |. .. PRYCHASCVPGGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP |
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| Kelch_1 | DDB0229963.AA | Kelch_1 | 1592-1637 | 32 | 1e-08 | 34.98 | Pfam | 1-45 (45) | Show / Hide |
Range on Protein: 1592-1637 Range on HMM: 1-45/45 Sequence Identity: 32% (15 aa) PRYGHTFTRYGNRFLLFGGYDGEQCLNDLYILEPETMCWSTVTNIK ||.||. . .... .||.|| |.||. ... ||| .|. ... . PRCGHGVCVHNGKIYVIGGCDG-QYLNSVECYDPETNQWTRCPPMP |
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| Kelch_2 | DDB0229963.AA | Kelch_2 | 1644-1662 | 42 | 0.158051 | 9.93 | Pfam | 1-19 (51) | Show / Hide |
Range on Protein: 1644-1662 Range on HMM: 1-19/51 Sequence Identity: 42% (8 aa) ERFGHTSTILGEKLIIFGG |..|.|. .|.|...||| PRYCHASCVPGGKIYVFGG |
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| Kelch_1 | DDB0229963.AA | Kelch_1 | 1644-1662 | 31 | 1.269918 | 6.0 | Pfam | 1-19 (45) | Show / Hide |
Range on Protein: 1644-1662 Range on HMM: 1-19/45 Sequence Identity: 31% (6 aa) ERFGHTSTILGEKLIIFGG | ||... .. |. ..|| PRCGHGVCVHNGKIYVIGG |
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| Kelch_1 | DDB0229963.AA | Kelch_1 | 1731-1780 | 15 | 0.009395 | 13.64 | Pfam | 1-45 (45) | Show / Hide |
Range on Protein: 1731-1780 Range on HMM: 1-45/45 Sequence Identity: 15% (8 aa) ERSFHSATRVGRNIVMVGGKKDDSNGNPIALRDCWVLSYR-MQWSKVSGVQ |..|... .. | .|| . .|....... . ||.... . PRCGHGVCVHNGKIYVIGGCDG------QYLNSVECYDPETNQWTRCPPMP |
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| Kelch_2 | DDB0229963.AA | Kelch_2 | 1731-1780 | 21 | 4.849959 | 4.28 | Pfam | 1-51 (51) | Show / Hide |
Range on Protein: 1731-1780 Range on HMM: 1-51/51 Sequence Identity: 21% (11 aa) ERSFHSATRVGRNIVMVGGKKDDSNGNPIALRDCWVLSYR-MQWSKVSGVQ |. |... .| |...|| .... .|. ...| |.. . .|..|... PRYCHASCVPGGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP |
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| Kelch_1 | DDB0229963.AA | Kelch_1 | 1784-1811 | 25 | 1.319805 | 5.94 | Pfam | 1-27 (45) | Show / Hide |
Range on Protein: 1784-1811 Range on HMM: 1-27/45 Sequence Identity: 25% (7 aa) PRYNFGLIKNGSKLFILGGKGNNNNINN ||...| . |... || . . |. PRCGHGVCVHNGKIYVIGGCDG-QYLNS |
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| Kelch_2 | DDB0229963.AA | Kelch_2 | 1784-1802 | 36 | 18.055938 | 2.11 | Pfam | 1-19 (51) | Show / Hide |
Range on Protein: 1784-1802 Range on HMM: 1-19/51 Sequence Identity: 36% (7 aa) PRYNFGLIKNGSKLFILGG |||. . |.|... || PRYCHASCVPGGKIYVFGG |
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| Kinase | DDB0229963.AA | Dicty4-Unclassified | 1907-2161 | 69 | 6.6e-217 | 726.89 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 1907-2161 Range on HMM: 1-263/263 Sequence Identity: 69% (184 aa) IKIDKEIGKGHFSKVLKGNWKGKDVAVKKLNSNKDKAREEMIQEFKAEVELLGSLQHPNLVTCYGYSLNP------MCIVMEFLPSGNLFELIHSKPSEQ |.||..|||||||||.|||||||||||||.|.||.|.||||||.||.|||.|||.||||||.||||..|| |||||||...|||||.|||||||| IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQ QQSIKLDSTLILAIAFDIARGMQHLHTRNIIHRDLKSSNLLMDKHFNIKIADLGIARETSFTQTMTTIG-TVAWTAPEILRHESYNQKADVYSYAIVLYE ||.||||.|||...|||||.|||||||||.||||.||||.||||||||||||.||.|...|...||||. |..|..||.|.|||||||.||||||..||| QQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYE LLTGEEPYQGIP-PMNAGILVASKGLRPELPDNCDPNWKKLVVWCWSEDPNKRPSFEEITNYL |.||.||||.|. .|||...|..|.|||..|||||..||||..|||..||||||....|..|| LATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL |
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| Kinase | DDB0229963.AA | Dicty4 | 1907-2163 | 49 | 1.3e-176 | 593.02 | In-house | 1-277 (277) | Show / Hide |
Range on Protein: 1907-2163 Range on HMM: 1-277/277 Sequence Identity: 49% (136 aa) IKIDKEIGKGHFSKVLKGNWKGKDVAVKKLNSNKDKAREEMIQEFKAEVELLGSLQHPNLVTCYGYSL----NP--MCIVMEFLPSGNLFELIHSKPSEQ |.|...||||.|..|.||.|.||.|||||||.......|.|..||..||.......|||.....|... .| ||||.|..|.|||..|.|.||||| INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ QQSIKLDSTLILA---IAFDIARGMQHLHTRN--IIHRDLKSSNLLMDKHFNIKIADLGIAR----ETSFTQ-TMTTIGTVAWTAPEILRHESYNQKADV |||||||..||.. .|||.||||..||..| ||||||||.|||.||....|..|.|... ...... .||..||..|.|||...|..||.|||| QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADV YSYAIVLYELLTGEEPYQ--GIPPMNAGILVASKGLRPELPDNCDPNWKKLVVWCWSEDPNKRPSFEEITNY--LTK ||..|||.|.||..|||| ..|.|.....|..|.|||..||.|.|.||.|..|||..||..|||||||... | YSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH |
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| Kinase | DDB0229963.AA | TKL | 1913-2161 | 30 | 1.5e-107 | 363.57 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 1913-2161
Range on HMM: 1-364/364
Sequence Identity: 30% (116 aa)
IGKGHFSKVLKGNWKG----------KDVAVKKLNSNKDKAREEMIQE---------------------FKAEVELLGSLQ--HPNLVTCYG--------
||.|.|..| ||.|.| |||||||..|. |. .....|| |. |.|.. .. |||.| ..|
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG
-YSLNP------MCIVMEFLPSGNLFELIHSKPSEQQQSIKLDSTLILAIAFDIARGMQHLHTRN--------IIHRDLKSSNLLMDKHFN---------
....| .|||||. | |.|....| ... .| ||||||..||..| ||||||||.|.| |....
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNP
-----IKIADLGIARETSFT---------------------QTMTTIGTVAWTAPEILRHE----------------SYNQKADVYSYAIVLYELLTGEE
.||.|.|..|. | . .||| .|| .| |||.|| . .|..|.||||..|||.|.||...
NADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR
PYQGIPPMNAG---------ILVASKGLRPELP------------DNCDPNWKKLVVWCWSEDPNKRPSFEEITNYL
||...|.| ..|..|||||..| ..|.| .||| .||..||.|||||.||. .|
PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
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| Kinase | DDB0229963.AA | MLK | 1907-2161 | 38 | 5.9e-95 | 321.76 | In-house | 1-291 (291) | Show / Hide |
Range on Protein: 1907-2161 Range on HMM: 1-291/291 Sequence Identity: 38% (111 aa) IKIDKEIGKGHFSKVLKGNWKGKD-----VAVKKLNSNK-DKAR-EEMIQEFKAEVELLGSLQHPN----LVTCYGYSLNP---MCIVMEFLPSGNLFEL |.. . ||.|.| || ||.|..|| ||||. .... ||.. .. ...|. |...| |.||| . || .|.| |||||... | |... IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV IHSKPSEQQ-------QSIKLDSTLILAIAFDIARGMQHLHTRN---IIHRDLKSSNLLMD------KHFNIKIADLGIARETSFT-QTMTT-IGTVAWT .|...|. .. | ... .|...||||. || ||||||||.|.| | .| . ||.| |..|. . . ..|. .||.|| LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM APEIL---RHESYNQKADVYSYAIVLYELLTGEEPYQ-GIPPMNAGILVASKGLRPELPDNCDPNWKKLVVWCWSEDPNKRPSFEEITNYL |||.. |.| |. |.||.|...||.|.||.|.||. .. || ... || .|||| .| .|.. |||| ||..||.||||| .| .| APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL |
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| Kinase | DDB0229963.AA | TKL-Unique | 1909-2161 | 36 | 1.2e-91 | 310.77 | In-house | 1-290 (290) | Show / Hide |
Range on Protein: 1909-2161 Range on HMM: 1-290/290 Sequence Identity: 36% (105 aa) IDKEIGKGHFSKVLKGNWKGKDVAVKKLNSNKDKAREEMIQEFKAEVELLGSLQ-HPNLVTCYGYSL------NPMCIVMEFLPSGNLFELIH-SKPSE- . . || | ...| || |.|..||.|... . . . ||.|||. || .. |. |||.|...||. . ||||||..| |.| ...| . . FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN -QQQSIKLDSTLILAIAFDIARGMQHLHTRN--IIHRDLKSSNLLMDKH-----FNIKIADLGIARETSFTQTMTTI-----------GTVAWTAPEILR ...||. ... .| |||.|| .||... ||||||||||.| | . .||||.| |... | .||.. |. | |||.|| NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR H--ESYNQKADVYSYAIVLYELLTGEE------PYQGIPPMNAGILVAS--KGLRPELPDNCDPNWKKLVVWCWSEDPNKRPSFEEITNYL . |..|.||||..|||.|..|.. ||||. . .|.. ...||..|..| .. ..| || || .||||.|| ..| MNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL |
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| Kinase | DDB0229963.AA | DRK | 1907-2163 | 42 | 1.1e-89 | 303.85 | In-house | 1-258 (258) | Show / Hide |
Range on Protein: 1907-2163 Range on HMM: 1-258/258 Sequence Identity: 42% (112 aa) IKIDKEIGKGHFSKVLKGNWKGKDVAVKKL-NSNKDKAREEMIQEFKAEVELLGSLQHPNLVTCYGYSLNP--MCIVMEFLPSGNLFELIHSKPSEQQQS ||| ||.| . | | | | ||||.| | | . |....||. |..|. | ||| . | .|| ||.||..| | | | .| IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNIND--ENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILH------DES IKLDSTLILAIAFDIARGMQHLHTRN--IIHRDLKSSNLLMDKHFNIKIADLGIAR----ETSFTQTMTTIGTVAWTAPEILRHESYNQKADVYSYAIVL |..| |.. ..||.|.|| || .| |||||||| ||| | |. .|.|| | . . . .|| .|| |||||.|| . | ||||||.|||| IEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVL YELLTGEEPYQGIPPMNAGILVASKGLRPELPDNCDPNWKKLVVWCWSEDPNKRPSFEEITNYLTK |..| . ||.|.|.. . | |.|| | .| | . .| ||.||| |||..|. | WECVTRQDPYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA |
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| Kinase | DDB0229963.AA | LRRK | 1907-2163 | 29 | 7.3e-86 | 291.57 | In-house | 1-351 (351) | Show / Hide |
Range on Protein: 1907-2163 Range on HMM: 1-351/351 Sequence Identity: 29% (103 aa) IKIDKEIGKGHFS-KVLKGNWKG----------------------------KDVAVKKLNSNK------------------------------DKAREEM .|| ..||.| | .| ...|.| ..||.||.| . . . LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA IQEFKAEVELLGSLQHPNLVTCYGYSLNPMCIVMEFLPSGNLFELIHSKPSEQQQSIK--LDSTLILAIAFDIARGMQHLHTRN--IIHRDLKSSNLLM- .|| || .. .|.|||.| .|....|.|.|||..| |.| ...|.| . .. .| .. .|.| || .||.||..|| .| |||||||| | |. FREFRHEVWIMSHLNHPNIVSLKGFCIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLW --D---------KHFNIKIADLGIAR-ETSFTQ--TMTTIGTVAWTAPEILR---HESYNQKADVYSYAIVLYELLTGE-EPYQGIP-P-----MNAGIL . | ..|||| || | ..|. ... |. | ||||.| |.|..|.|.||....|.||||.. |..... . |. . SSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIED VASKGLRPELPDN-CDP-----NWKKLVVWCWSEDPNKRPSFEEITNYLTK ..|||| .| . | | ..| ..||..||.|||.|..|. | KIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ |
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| Kinase | DDB0229963.AA | Pkinase_Tyr | 1907-2161 | 31 | 5.3e-74 | 251.26 | Pfam | 1-270 (270) | Show / Hide |
Range on Protein: 1907-2161 Range on HMM: 1-270/270 Sequence Identity: 31% (87 aa) IKIDKEIGKGHFSKVLKGNWK------GKDVAVKKLNSNKDKAREEM--IQEFKAEVELLGSL-QHPNLVTCYGYSL---NP--MCIVMEFLPSGNLFEL |...|..|.|.| .| || || . .||||.| |..| .| ...| .|.... .| .|||.| .|| . | ..||||. | |.| . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML---KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY IHSKPSEQQQSIKLDSTLILAIAFDIARGMQHLHTRNIIHRDLKSSNLLMDKHFNIKIADLGIARET-----SFTQTMTTIGTVAWTAPEILRHESYNQK ... . .|. .| ....||.||..|. .|.||||| | | .. . .||.| | || .... . . |.||| ... .. | LRKHR---EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTK ADVYSYAIVLYELLT-GEEP-YQGIPPMNAGILVASKGLRPELPDNCDPNWKKLVVWCWSEDPNKRPSFEEITNYL ||.|. ....|..| ||.| |.|... ... .| | . |.|| . .| || .||..||.|.|| . | SDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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| Kinase | DDB0229963.AA | TyrKc | 1907-2161 | 28 | 2.3e-72 | 247.66 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 1907-2161 Range on HMM: 1-280/280 Sequence Identity: 28% (83 aa) IKIDKEIGKGHFSKVLKGNWKGKDVAVKKLNSNKDKAREEMIQEFKAEVELLGSL--QHPNLVTCYGYSL---------NPMCIVMEFLPSGNLFELIHS |. .|..| |.| .| || || .||||.|.... ...| | ... .| .|||.| .||. . |..||||. | |.| . ... ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK KPSEQQQSIKLDSTLILAIAFDIARGMQHLHTRNIIHRDLKSSNLLMDKHFNIKIADLGIARETSFT-------QTMT------TI--GTVAWTAPEILR . . | | ....||.||..|| .|.||||| | | .. . .||.| | .|. .. . . . |.||| .. HRPK------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN HESYNQKADVYSYAIVLYELLT-GEEPYQGI----PPMNAGILVASKGLRPELPDN--------CDPNWKKLVVWCWSEDPNKRPSFEEITNYL . .. | ||.|. ....|..| |..|| |. . | .| |.. |.| | . .. .|| |||..||.|.|| .. YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | DDB0229963.AA | TK | 1907-2161 | 17 | 1.2e-68 | 228.95 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 1907-2161
Range on HMM: 1-486/486
Sequence Identity: 17% (83 aa)
IKIDKEIGKGHFS---KVLKGNWKGK---------------------------DVAVKKLNSNKDKAREEMIQ-------------EFKAEVELLGS--L
|.. |..|.|.| .| || |.|. .|||| | . . . ||... |. .| ... . .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
QHPNLVTCYGYSLNP--------------MCIVMEFLPSGN----LFELIHSKPSEQQQSIK--------------------------------------
.|||.| .||... . ..||||. | |. | . .... . |..
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY
-------------------------------LDSTLILAIAFDIARGMQHLHTR------NIIHRDLKSSNLLMDKHFN-----------IKIADLGIA-
|. | ....||.||..|| . |..|||| | | ... . .|||| | .
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR
-------RETSFTQTMTTIGT----------------------------VAWTAPEILRHES---------YNQKADVYSYAIVLYELLT-GEEPYQGIP
|. . .. .. . |.||| |.. . | ||.|. ....|..| |.||| |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM
PM--------NAGILVASK---------------GLRPELPDNCD--------------PNWKKLVVWCWSEDPNKRPSFEEITNYL
. |. .. . ..|.. |..| . . | ||..||..||.|... ..|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
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| Kinase | DDB0229963.AA | TK-Unique | 1907-2161 | 29 | 6.7e-67 | 228.57 | In-house | 1-294 (294) | Show / Hide |
Range on Protein: 1907-2161 Range on HMM: 1-294/294 Sequence Identity: 29% (88 aa) IKIDKEIGKGHFSKVLKGNWKG--------KDVAVKKLNSNKDKAREEMIQEFKAEVELLGSLQ-HPNLVTCYGYSL---NPMCIVMEFLPSGNLFELIH ......||.| |. | .| .| | ||||.| ||.|... |.|. | ... .| |||.|.|.|.. .|..|.||..| ||| ... LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKML---KDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLR SKPSEQQQS-----IK--------------LDSTLILAIAFDIARGMQHLHT--RNIIHRDLKSSNLLMDKHFNIKIADLGIARETSFTQTMTTIGT--- .. .. |. .| ... . . .|..||.||..|. ..|.|||| ..| |. ....||.|.|.||... .. .... TCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGR --VAWTAPEILR--HESY-NQKADVYSYAIVLYELLT-GEEPYQGIPPMNAGILVA-SKGLRPELPDNC-DPNWKKLVVWCWSEDPNKRPSFEEITNYL ..| |||.|. |. | . | ||.|......|..| |. || |.|. . |. . .| |...|..| . .| ||...| .||||..|.. | IPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKD--IMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL |
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| Kinase | DDB0229963.AA | Dicty5 | 1907-2165 | 36 | 1.1e-66 | 227.87 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 1907-2165
Range on HMM: 1-260/260
Sequence Identity: 36% (98 aa)
IKIDKEIGKGHFSKVLKGNWKGKDVAVKKLNSNK----DKAREEMIQEFKAEVELLGSLQ--HPNLVTCYG---YSLNPMCIVMEFLPSGNLFELIHSKP
. . . | | .| .| ||.|||.| . . | ..||. || .. | |||.. ||| | . .| |. .| ||.. .
VSFHDWIASGASGRVYNGIYKGMDVAIKVYSQENCMCFD------WNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQR
SEQQQSIKLDSTLILAIAFDIARGMQHLHTRNIIHRDLKSSNLLMDKHFNIKIADLGIARETSFTQTMTT-IGTVAWTAPEILRHESYNQKADVYSYAIV
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KTTGQPIAY--FQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIV
LYELLTGEEPYQGIPPMNAGILVASKGLRPELPDNCDPNWKKLVVWCWSEDPNKRPSFEEITNYLTKTF
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LWEMFTRKEPYDNINNWNIPVMVM-KGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
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| Kinase | DDB0229963.AA | Pkinase | 1907-2161 | 26 | 1.4e-65 | 228.99 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 1907-2161
Range on HMM: 1-293/293
Sequence Identity: 26% (79 aa)
IKIDKEIGKGHFSKVLKGNWKGKD--VAVKKLNSNKDKAREEMIQEFKA--EVELLGSLQHPNLVTCYGYSL--NPMCIVMEFLPSG----NLFELIHSK
..| . ||.| |..| |. .|| ||||.. .|....... |. |.... .|.||| |..|.. . ...|||... | ||..|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKII--KKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-
PSEQQQSIKL--DSTLILAIAFDIARGMQHLHTRNIIHRDLKSSNLLMDKHFNI----KIADLGIAR---ETSFTQTMTTIGTVAWTAPEILR-HESYNQ
... .. . . .. |.||....| ..|||||||..|.|.|.. .| ||.| |.|. . . . ..| || . |||..| .. | .
----WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGP
KADVYSYAIVLYELLTGEEPYQGI---PPMNAGILVASKGLRPELPDNCD-----------------------PNWKKLVVWCWSEDPNKRPSFEEITNY
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KVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQH
--L
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PWF
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| Kinase | DDB0229963.AA | S_TKc | 1907-2161 | 27 | 2.4e-63 | 217.66 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 1907-2161 Range on HMM: 1-231/231 Sequence Identity: 27% (73 aa) IKIDKEIGKGHFSKVLKGNWKG--KDVAVKKLNSNKDKAREEMIQEFKAEVELLGSLQHPNLVTCYGYSL-NPMCIVMEFLPS--GNLFELIHSKPSEQQ .| ..|||| |.|| |. .|. . ||.|... . .. |...| . .|||.|..|.. . ...|||... |.||..|...... YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGL QSIKLDSTLILAIAFDIARGMQHLHTRNIIHRDLKSSNLLMDKHFNIKIADLGIARETSFTQTMTTIGTVAWTAPEILRHESYNQ-KADVYSYAIVLYEL . ... . .. |.......| ..||||||| .|.|.|. .|||.| |.||. .| .|| . |||.| .|. |.|..| ..|||. R-FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM LTGEEPYQGIPPMNAGILVASKGLRPELPDNCDPNWKKLVVWCWSEDPNKRPSFEEITN---------YL |.|. |.. . . | .. .| | .. |. ||.|||. |. . .. LCGYPPFP-------QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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