DDB0229850

Species: Slime mold
Alias: DdisK188, DDB0229850
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: ARK

Sequence

Name Sequence Type Origin Length Description Download
DDB0229850.AA Protein None 352 None Fasta, JSON
DDB0229850.kin_dom Protein Kinase Domain None 276 None Fasta, JSON

Protein domain

Protein domains of DDB0229850.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0229850.AA ARK 51-325 51 3.1e-195 654.91 In-house 1-280 (280) Show / Hide
Range on Protein: 51-325
Range on HMM: 1-280/280
Sequence Identity: 51% (146 aa)

IEYVCRLGSGSLCRVYKGRLNGKPVAIKVFSPIR-----FEEFKTEFLMMQSLRSSPFLISFYGVSIVEEPQKQCYCIITEFCSRDSLYHIMTDRLIEIG
.||.|..||||.|.||||...||.|||||...|.     .||||.|| .|.|.| ||....|||..|..|||||..|...|.|||.||||||.......|
LEYTCKIGSGSSCKVYKGKYRGKEVAIKVLKSIMTDSMQIEEFKKEFQIMSSIR-SPHVVYFYGACIEPEPQKQKLCMVMEYCSRGSLYHIMNNNKMDFG

WNRFFQFSMQIILGLQSLHNRKPKPIVHRDVTSLNILVNEDWECKISNFSASRFNCLNTEYINSNNQNKSFAFCSPESSDFQDIDDDYTSLSSSITSKSD
|.|||...||...|...|||..| .|||||..|||.||||.|.||...|..||||............. .||.|.||...||||||||.|.....|.|||
WDRFFKWMMQMVRGINCLHNWTP-QIVHRDLKSLNLLVNENWTCKVCDFGLSRFNTMSNQETLGKMRG-TFAYCAPEVYYFQDIDDDYVSNGKHYTTKSD

IYSFGIIMFELISRIINGEYSHPFSEFKDIK--NDFQLLLS-SKNGLRPSLPNICPEPLEKLYKQCVDQSPLNRPSCEEVIIS
.||.||||.|...|.|||.|..|.||.|.||  .|||.|.. |||.|||..|..|||.|..|...|.||.| |||||||....
VYSMGIIMWEMVYRCINGCYMRPYSEYKHIKNAFDFQILIQTSKNNLRPTIPQNCPEQLKNLIQCCWDQDPDNRPSCEEIMEE

Kinase DDB0229850.AA TKL 57-326 22 2e-80 273.5 In-house 1-364 (364) Show / Hide
Range on Protein: 57-326
Range on HMM: 1-364/364
Sequence Identity: 22% (85 aa)

LGSGSLCRVYKGRLNG----------KPVAIKVFSPIR-----------------------------FEEFKTEFLMMQSLRSSPFLISFYGVSIVEEP-
.|||. . ||||...|          |.||.|.|.                                |..|. | .|| | .. | ...|.|... ... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

--------QKQCYCIITEFCSRDSLYHIMTDRLIEIGWNRFFQFSMQIILGLQSLHNRKP-----KPIVHRDVTSLNILVNEDWE--------------C
        ..  .||..|.|.. ||.|...       |.........| .|.. ||...|     .||.||| .| ||||.|.|.              |
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KISNFSASRFNCLNTEYI-----------------NSNNQNKSFAFCSPESSDFQDIDDDYTSL-----SSSITSKSDIYSFGIIMFELISRIINGEYSH
||. |  |||.. ...                   ....|  ......||  . |. .... ..     ... . |.|.|||||...|...| .      
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR------

PFSEFKDIKNDFQL---------LLSSKNGLRPSLP------------NICPEPLEKLYKQCVDQSPLNRPSCEEVIISL
    ..|.... ..          . ...|||| .|            . ||... || ..| |. | .|||..|..  |
---PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase DDB0229850.AA TKL-Unique 53-326 27 7e-53 182.01 In-house 1-290 (290) Show / Hide
Range on Protein: 53-326
Range on HMM: 1-290/290
Sequence Identity: 27% (83 aa)

YVCRLGSGSLCRVYKGRLNGKPVAIKVFSP---IRFE---EFKTEFLMMQSLRSSPFLISFYGVSIVEEPQKQCYCIITEFCSRDSLYHIMT--------
 .  .|.|. ..||||  .|.|||||.|.|   ...|   ||. |   |  |. .|..  ..|... . ..   .||..|.|.. |||   .        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-DRLIEIGWNRFFQFSMQIILGLQSLHNRKPKPIVHRDVTSLNILVNED-----WECKISNFSASRFNCLNTEYINSNN-------QNKSFAFCSPESSD
  . ... .... ..  .| .|.  ||...|. | ||| .|.|.||...     |  ||. |. |.||  ... .|...         .||   .||   
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPE---

FQDIDDDYTSLS-SSITSKSDIYSFGIIMFELISRIINGEYSHPFSEFKDIKNDFQLLLSSKNGLRPSLPNICPEPLEKLYKQCVDQSPLNRPSCEEVII
        .. . . .. |||.|||||.. |...| |   |  |.... ... ..... . . ..|| .|| ||. . .| .|| .. | .||| .|.| 
-------VLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQ-WCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIH

SL
.|
RL

Kinase DDB0229850.AA MLK 51-199 26 1.1e-21 72.11 In-house 1-182 (291) Show / Hide
Range on Protein: 51-199
Range on HMM: 1-182/291
Sequence Identity: 26% (49 aa)

IEYVCRLGSGSLCRVYKGRLNGKP-----VAIKVFS------------PIRFEEFKTEFLMMQSLRSSPFLISFYGVSIVEEPQKQCYCIITEFCSRDSL
|.    .|||| . |.|||  .|      ||.| .                ||..  .. ... .  .|  | ||||.. ..   ...||..|.|.  ||
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP---CHFCIVMEYCEGGSL

YHIMTDRL-------------IEIGWNRFFQFSMQIILGLQSLHNRKPKPIVHRDVTSLNILVNE------DWECKISNFSASRF
|..  ..              . .    ......|.  |.. ||. .||||.|||  | |||. |      .  .||. | .||.
YNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRD

Kinase DDB0229850.AA Pkinase_Tyr 51-192 25 7.5e-20 67.85 Pfam 1-153 (270) Show / Hide
Range on Protein: 51-192
Range on HMM: 1-153/270
Sequence Identity: 25% (40 aa)

IEYVCRLGSGSLCRVYKGRLN------GKPVAIKVF---SPIR---FEEFKTEFLMMQSLRSSPFLISFYGVSI-VEEPQKQCYCIITEFCSRDSLYHIM
|.    ||.|.  .||||...      . |||.|.    .  .    |.|  |  .| .| . | ....||| .  .||.   ..|..|..   .|..  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLLDYL

TDR---LIEIGWNRFFQFSMQIILGLQSLHNRKPKPIVHRDVTSLNILVNEDWECKIS
 ..      .   .  |...||  |.. |....   ..|||.   |.||.|.  .||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKIC

Kinase DDB0229850.AA Dicty4 51-194 29 5.6e-18 56.71 In-house 1-158 (277) Show / Hide
Range on Protein: 51-194
Range on HMM: 1-158/277
Sequence Identity: 29% (47 aa)

IEYVCRLGSGSLCRVYKGRLNGKPVAIKVF--SPIRF-----EEFKTEFLMMQSLRSSPFLISFYGVSIVEEPQKQCYCIITEFCSRDSLYHIMTD----
|    |.|.||.  ||||.  || ||.|..    . |     .||. |   | ..|  | .. |.| ..    ..   || ||.... .|| .  |    
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIR-HPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

--RLIEIGWNRFFQ---FSMQIILGLQSLHNRKPKPIVHRDVTSLNILVNEDWECKISNF
    |.. | .. .       . .|.. ||.. |  |.|||  | |.|| ..|  |.. |
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLVDKNWRVKVCDF

Kinase DDB0229850.AA LRRK 241-328 29 1e-17 59.23 In-house 260-351 (351) Show / Hide
Range on Protein: 241-328
Range on HMM: 260-351/351
Sequence Identity: 29% (29 aa)

TSKSDIYSFGIIMFELISRIINGEYS-HPFSEFK-DIKNDFQLLLSS--KNGLRPSLPNI-CPE-----PLEKLYKQCVDQSPLNRPSCEEVIISLNQ
| |.|.||||.|..||..|      . ||| |..   .  .. ...   ..||||..|.  ||.      ...| ..| .. |..||. ....  | |
TEKVDCYSFGMILWELLTR------QHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ

Kinase DDB0229850.AA TK 51-194 15 3.5e-17 53.44 In-house 1-295 (486) Show / Hide
Range on Protein: 51-194
Range on HMM: 1-295/486
Sequence Identity: 15% (46 aa)

IEYVCRLGSGSLC---RVYKGRLNGK---------------------------PVAIKVFS---PIRFEEFKT--------------EFLMMQSLRS---
|...  ||.|  .   .||||...|.                           |||.|.     .   |||.               | ..|. ...   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-SPFLISFYGVSIVEEPQ--------KQCYCIITEFCS-RD----SLYHIMTDR----------------------------------------------
  | ....|||.  .||.        .. ..|..|...  |     . .  . |                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------LIEIGWNRFFQ-------------------FSMQIILGLQSLHNRKPKPI----VHRDVTSLNILVNEDWE-----------CKISNF
        . ...   . |                   ...||  |.. || .. .      ||||.   |.||.|.             |||. |
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADF

Kinase DDB0229850.AA RAF 51-194 31 3.6e-17 51.92 In-house 1-147 (282) Show / Hide
Range on Protein: 51-194
Range on HMM: 1-147/282
Sequence Identity: 31% (48 aa)

IEYVCRLGSGSLCRVYKGRLNGKPVAIKVF-----SPIRFEE---FKTEFLMMQSLRSSPFLISFYGVSIVEEPQKQCYCIITEFCSRDSLYHIMTDRLI
..   | ||||   ||.|.  |. ||.|.      .|  .     || |  ...  |    |  |.|   . .|| . | |.|..|   |||| .   . 
VMVMTRIGSGSFGTVYRGHWHGD-VAVKMLNVNDPTPEQMQADVFFKNEVAVYKKTRHCNILL-FMG--YMSKPQTNTYAIVTQWCEHSSLYHHIHVQET

--EIGWNRFFQFSMQIILGLQSLHNRKPKPIVHRDVTSLNILVNEDWECKISNF
  .   .  .. | |. .|.  ||    | |.|||  | ||.  ||   ||  |
REKFDMHWLIDISRQVCQGMDYLHA---KNIIHRDLKSNNIFLHEDMTVKIGDF

Kinase DDB0229850.AA Dicty5 59-199 31 3.7e-17 55.6 In-house 9-153 (260) Show / Hide
Range on Protein: 59-199
Range on HMM: 9-153/260
Sequence Identity: 31% (48 aa)

SGSLCRVYKGRLNGKPVAIKVFSPIR-----FEEFKTEFLMMQSLRS--SPFLISFYGVSIVEEPQKQCY-CIITEFCSRDSLYHIMTDRLI----EIGW
||.  |||.|  .|. |||||.|.        .||. |  .| |.     | .| .||       . . |  ..||.|.. ||     |.       | .
SGASGRVYNGIYKGMDVAIKVYSQENCMCFDWNEFYREVTIM-SIFQSDHPNFIRCYGA----HQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAY

NRFFQFSMQIILGLQSLHNRKPKPIVHRDVTSLNILVNEDWECKISNFSASRF
     . . |  ... ||    . |.|||. |.|.|..|.|. ||  |  |||
FQQLHMAIDIAQSMRHLHS---MNIIHRDLKSMNFLITENWKIKIIDFGTSRF

Kinase DDB0229850.AA TyrKc 51-326 22 4e-17 54.13 SMART 1-280 (280) Show / Hide
Range on Protein: 51-326
Range on HMM: 1-280/280
Sequence Identity: 22% (70 aa)

IEYVCRLGSGSLCRVYKGRLNGKPVAIKVFSPIRFEEFKTEFLMMQSL-RSSPFLISFYGVSIVE-------EPQKQCYCIITEFCSRDSLYHIMTDRLI
|.    ||.|  ..||||...  .||.|.  .   |.|  |  .| .|  . | .. .||| . .       ||    ..|..|...  .| .   ..  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEP----LMIVMEYMPHGDLKDYLRKHRP

EIGWNRFFQFSMQIILGLQSLHNRKPKPIVHRDVTSLNILVNEDWECKISNFSASRFNCLN------TEYINSN---NQN--KSFAFCSPESSDFQDIDD
.. .  . .|. ||  | . || .   ...|||    |.||.|.  .||| |  ||.          ..|. .    . .       ..||.        
KLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-------

DYTSLSSSITSKSDIYSFGIIMFELISRIINGEYSHPFSE--FKDIKNDFQLLLSSKNGLRPSLPNI--------CPEPLEKLYKQCVDQSPLNRPSCEE
      .  |.|||..|||. |.|. ..        | ..  ..  .......   |.| |.  |          ||. . .. ||| .  | .||. .|
----NYGKFTTKSDVWSFGVCMWEIFTYG-----QQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSE

VIISL
..  .
IHECF

Kinase DDB0229850.AA MLK 243-326 32 1.1e-16 54.47 In-house 216-291 (291) Show / Hide
Range on Protein: 243-326
Range on HMM: 216-291/291
Sequence Identity: 32% (27 aa)

KSDIYSFGIIMFELISRIINGEYSHPFSEFKDIKNDFQLLLSSKNGLRPSLPNICPEPLEKLYKQCVDQSPLNRPSCEEVIISL
|.|..|.|... |...|       .|..   .... . .     ||||| .|. |||...||.||| .| | .|||  ...  |
KCDVWSWGVVLWEMLTR------EVPYK--QHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase DDB0229850.AA S_TKc 51-333 18 8.5e-16 54.75 SMART 1-231 (231) Show / Hide
Range on Protein: 51-333
Range on HMM: 1-231/231
Sequence Identity: 18% (54 aa)

IEYVCRLGSGSLCRVYKGRLNG--KPVAIKVFSPIRFEEFKTEFLMMQSLRSSPFLISFYGVSIVEEPQKQCYCIITEFCSR--DSLYHIMTDRL-----
 | .  .|.|.  .|||.| ..  . ||||. .    | .. |  ....    |... .|.|        .......|.|.    .|.... .|      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--IEIGWNRFFQFSMQIILGLQSLHNRKPKPIVHRDVTSLNILVNEDWECKISNFSASRFNCLNTEYINSNNQNKSFAFCSPESSDFQDIDDDYTSLSSS
  .   . ||.    ||...|. .|...   |.|||.   |||..|  . ||. |  .|.          . .  .  ...||                .
FPFPE-HARFYMY--QICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL--------------G

ITS-KSDIYSFGIIMFELIS-RIINGEYSHPFSEFKDIKNDFQLLLSSKNGLRPSLPNICPEPLEKLYKQCVDQSPLNRPSCEEVII--SLNQIRSFY
 .  |.|..|.|.|..|... .       ...  || |.                     ....  . ..| .  | .||.. |.    ..  .  . 
YGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG---------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase DDB0229850.AA Dicty4 241-328 31 2.9e-15 47.53 In-house 195-277 (277) Show / Hide
Range on Protein: 241-328
Range on HMM: 195-277/277
Sequence Identity: 31% (29 aa)

TSKSDIYSFGIIMFELISRIINGEYSHPFS-EFKDIKNDFQLLLSSKN-GLRPSLPNICPEPLEKLYKQCVDQSPLNRPSCEEVIIS--LNQ
..|.| |||||. .|.  | .      |.. .....   .|.  .  | .|||..|. || .. .| . | | .| .||| ||.|    |. 
NEKADVYSFGIVLWEILTRQE------PYQKHHMPY---MQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase DDB0229850.AA Pkinase 51-192 22 3e-15 54.98 Pfam 1-154 (293) Show / Hide
Range on Protein: 51-192
Range on HMM: 1-154/293
Sequence Identity: 22% (36 aa)

IEYVCRLGSGSLCRVYKGRLNGKP--VAIKVFSPIRFEEFKT-------EFLMMQSLRSSPFLISFYGVSIVEEPQKQCYCIITEFCSRD----SLYHIM
.. . ..||||  .|||..  | .  ||.|...  . .. |        |  .|..| ..|. . .|..       |. .....|.|  .    .|....
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED----KDHIYMVMEYCEGGLYVMDLFDYI

T-DRLIEI--GWNRFFQFSMQIILGLQSLHNRKPKPIVHRDVTSLNILVNEDWEC----KIS
. .|   .   ..    .  ||. ||. .|..    |.|||. . |||.... ..    ||.
STWRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKIC

Kinase DDB0229850.AA Dicty4-Unclassified 241-326 31 4.1e-13 41.23 In-house 186-263 (263) Show / Hide
Range on Protein: 241-326
Range on HMM: 186-263/263
Sequence Identity: 31% (27 aa)

TSKSDIYSFGIIMFELISRIINGEYSHPFSEFKDIKNDFQLLLSSKNGLRPSLPNICPEPLEKLYKQCVDQSPLNRPSCEEVIISL
..|||.||......||.     |.   |. |   | |    .  .| .||| .|  |.  . || | |   .|  ||. ...|  |
NQKSDVYSYAMMLYELAT----GD--EPYQEIQSIMN-AARSVCDK-KLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL

Kinase DDB0229850.AA Dicty4-Unclassified 51-198 29 4.7e-13 41.01 In-house 1-157 (263) Show / Hide
Range on Protein: 51-198
Range on HMM: 1-157/263
Sequence Identity: 29% (47 aa)

IEYVCRLGSGSLCRVYKGRLNGKPVAIKVF----SPIR---FEEFKTEFLMMQSLRSSPFLISFYGVSIVEEPQKQCYCIITEFCSRDSLYHIMT-----
|     .| | . .|.||   || ||.| |       |    ..|| |  .. |. . | |.  || .|     |  .||..||  .  |  .       
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSI-QHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSE

-DRLIEIGWNRFFQFSMQIILGLQSLHNRKPKPIVHRDVTSLNILVNEDWECKISNFSASR
 .. |         . . |  |.| || |    ..|||. | |||.  .   ||  |  ||
QQQPIKLDDTLIIKYAFDIAQGMQHLHTRN---FIHRDIKSSNILMDKHFNIKIADFGISR

Kinase DDB0229850.AA LRRK 51-202 20 5e-12 38.82 In-house 70-300 (351) Show / Hide
Range on Protein: 51-202
Range on HMM: 70-300/351
Sequence Identity: 20% (49 aa)

IEYVCRLGSGSLC-RVYKGRLNG----------------------------KPVAIKVFSPIR-------------------------------------
...   .|.|.   .||.....|                            ..||||..  ..                                     
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

FEEFKTEFLMMQSLRSSPFLISFYGVSIVEEPQKQCYCIITEFCSRDSLYHIMT----DRL----IEIGWNRFFQFSMQIILGLQSLHNRKPKPIVHRDV
| ||  |  .| .|.  | ..| .|..|      . .|...|. .  .||| .     |..    ..|.|. . . ..||  |.. ||...| ||.||| 
FREFRHEVWIMSHLN-HPNIVSLKGFCI------HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDL

TSLNILV---N---------EDWECKISNFSASR-FNCL
.| |||.   .         ..  .||. |. || | |.
KSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCF

Kinase DDB0229850.AA TK 241-326 20 4.9e-10 29.04 In-house 372-486 (486) Show / Hide
Range on Protein: 241-326
Range on HMM: 372-486/486
Sequence Identity: 20% (24 aa)

TSKSDIYSFGIIMFELIS---RIINGEYSH--------PFSEFKDIKNDFQLLL-----SSKNGLRPSLPNICP--------------EPLEKLYKQCVD
|.|||..|||. |.|. .       |. |.        .   .. ...  .| .     .  ...|.  |  ||              | .. | .|| .
TTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRL-CRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWH

QSPLNRPSCEEVIISL
  |  ||. ...   |
YDPEDRPTFSQLHEQL

Kinase DDB0229850.AA RAF 241-328 25 7.2e-09 24.57 In-house 199-282 (282) Show / Hide
Range on Protein: 241-328
Range on HMM: 199-282/282
Sequence Identity: 25% (23 aa)

TSKSDIYSFGIIMFELISRIINGEYSHPF-SEFKDIKNDFQLLLSSKNGLRPSLPNI---CPEPLEKLYKQCVDQSPLNRPSCEEVIISLNQ
. .||.|||||.|.||..| .      |. .. ..   |  . .  .  ||| |  .   ||. . .|.. |.   . .||. .... ... 
SFQSDVYSFGIVMYELMTRHM------PYGCHIWN--RDQIIFMCGRGYLRPDLSKVRQDCPKAMHRLMEDCWKFQREERPLFQQILKRITV

Kinase DDB0229850.AA Pkinase_Tyr 241-326 26 7.6e-07 23.81 Pfam 192-270 (270) Show / Hide
Range on Protein: 241-326
Range on HMM: 192-270/270
Sequence Identity: 26% (23 aa)

TSKSDIYSFGIIMFELISRI-INGEYSHPFSEFKDIKNDFQLLLSS-KNGLRPSLPNICPEPLEKLYKQCVDQSPLNRPSCEEVIISL
|.|||..|||. |.|....  .         .....  .....    ..| |   |  ||... .| ||| .. | .||. .|..  |
TTKSDVWSFGVLMWEIFTYGEQP--------TYPGM-SNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase DDB0229850.AA Dicty5 288-330 39 1.7e-05 14.86 In-house 218-260 (260) Show / Hide
Range on Protein: 288-330
Range on HMM: 218-260/260
Sequence Identity: 39% (17 aa)

GLRPSLPNICPEPLEKLYKQCVDQSPLNRPSCEEVIISLNQIR
| || .|  ||    .| | |  | | ||||  |..  ...| 
GERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII

Kinase DDB0229850.AA Dicty5 241-259 47 0.000713 9.21 In-house 181-199 (260) Show / Hide
Range on Protein: 241-259
Range on HMM: 181-199/260
Sequence Identity: 47% (9 aa)

TSKSDIYSFGIIMFELISR
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HQKCDVYSFGIVLWEMFTR

Kinase DDB0229850.AA Pkinase 240-326 16 0.008676 10.94 Pfam 189-293 (293) Show / Hide
Range on Protein: 240-326
Range on HMM: 189-293/293
Sequence Identity: 16% (19 aa)

ITSKSDIYSFGIIMFELISRIINGEYSHPFSEF---KDIKNDFQLLLSSKN-GLRPSLPNICP-------------------EPLEKLYKQCVDQSPLNR
...|.|..|.|.|..|....        ||..    ..  .. |..   .   |. . |. |.                   |.. .. | | .. |  |
YGPKVDMWSCGCILYEMLCGR------PPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKR

PSCEEVIIS--L
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PTAEQILQHPWF