Gene DDB0218878e (Slime mold)
DDB0218878e
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| DDB0218878e.AA | Protein | None | 966 | None | Fasta, JSON |
| DDB0218878e.kin_dom | Protein Kinase Domain | None | 258 | None | Fasta, JSON |
Protein domains of DDB0218878e.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| LIM | DDB0218878e.AA | LIM | 4-55 | 25 | 5.7e-07 | 30.39 | SMART | 1-52 (52) | Show / Hide |
Range on Protein: 4-55 Range on HMM: 1-52/52 Sequence Identity: 25% (13 aa) RCGVCKYIISDCERYVSDNTFYHVKCFICKICKCELPPCFRGKHASLMCGDC .|. |. |.. .... .. .|..|| | .|.. | . | |. .. | .| KCARCNKPIYGDQVMRAMGKHWHPECFCCCHCNKPLGGTFYEKDGKPYCKHC |
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| LIM | DDB0218878e.AA | LIM | 5-41 | 31 | 0.001429 | 15.52 | Pfam | 1-38 (60) | Show / Hide |
Range on Protein: 5-41 Range on HMM: 1-38/60 Sequence Identity: 31% (12 aa) CGVCKYIISDCERY-VSDNTFYHVKCFICKICKCELPP |. |. |.| .. . | .|..||.| |...| | CAGCNKPIYDRYYVMRAMNKVWHPECFCCCHCQKPLTP |
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| LIM | DDB0218878e.AA | LIM | 63-113 | 34 | 2.6e-09 | 38.2 | SMART | 1-52 (52) | Show / Hide |
Range on Protein: 63-113 Range on HMM: 1-52/52 Sequence Identity: 34% (18 aa) KCFKSHFPIHS-VSVVARNKEFHNNCFTCISCNEIIKGGFQYSDELFYCSKC ||.. . || . ..|..| .| .||.| || . |.| |. .|| .| KCARCNKPIYGDQVMRAMGKHWHPECFCCCHCNKPLGGTFYEKDGKPYCKHC |
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| LIM | DDB0218878e.AA | LIM | 70-113 | 32 | 2e-06 | 25.84 | Pfam | 7-55 (60) | Show / Hide |
Range on Protein: 70-113 Range on HMM: 7-55/60 Sequence Identity: 32% (16 aa) PIHSVSVV--ARNKEFHNNCFTCISCNEIIKGG--FQYSDE-LFYCSKC ||.. .| |.|| .| .||.| |.. .. | . |. ..|| .| PIYDRYYVMRAMNKVWHPECFCCCHCQKPLTPGDECYEHDGNKLYCKHC |
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| Kinase | DDB0218878e.AA | Dicty5 | 702-956 | 62 | 2.5e-210 | 705.04 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 702-956 Range on HMM: 1-260/260 Sequence Identity: 62% (162 aa) VIFGDVIAAGASGKVYKGIYKGRDVAIKVYSSEN-FCFNIDEFDREVTIMSLIDSDHPNFTRFYGANKQNKKYLFHVSELVKSGSLRDLLLDKEK----P |.|.|.||.||||.||.|||||.||||||||.|| .||...||.|||||||...||||||.|.|||...|.||.|||.|....|||...|.|..| | VSFHDWIASGASGRVYNGIYKGMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQP LLYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTAKVIDFGTSRNVDLAKHMTMNLGTSCYMSPELFKGNGYDETCDVYAFGIVLWEIIARK ..||.||..|.|||..|.||||...|||||||.|.||||....|.|||||||.||...||||..||.|.|..|||.|..|...||||.|||||||...|| IAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRK EPYENINSWSIPVMVAKGDRPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICDTLKKIS |||.|||.|.|||||.||.|||||.|||.|.|.|||.||..||..||||||||.....|. EPYDNINNWNIPVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII |
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| Kinase | DDB0218878e.AA | TKL | 708-952 | 27 | 5.1e-96 | 325.31 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 708-952
Range on HMM: 1-364/364
Sequence Identity: 27% (102 aa)
IAAGASGKVYKGIYKG----------RDVAIKVYSSEN-FCFNIDE-----------------------FDREVTIMSLIDSDHPNFTRFYGANKQNKK-
| |..|.||||...| .|||.|...|.| .|.. . | .|. ||... .||| .|.|. .....
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG
-----------YLFHVSELVKSGSLRDLLLDKEKPLLYFTQLSIASDIANAMKHLHSIG--------VIHRDLKSLNVLITEDFT--------------A
.|. | |... |||...|. ...| ||| .| .||| . .||||||| |.|. |..| .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC
KVIDFGTSRNVDLAKHMTMN--------------------LGTSCYMSPELFKGN----------------GYDETCDVYAFGIVLWEIIARKEPYENIN
|. |||.||... ..|... || ..|.||...|. |.| ||||.||||||||..|..||....
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP
S----------WSIPVMVAKGDRPTIP------------ADCPSEYSKLIKACWTDKPKKRPSFKEICDTL
. . . . . || ||.|| ||| ...||.. || .|.|||||.|| ..|
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
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| Kinase | DDB0218878e.AA | TKL-Unique | 704-952 | 32 | 2.4e-82 | 279.87 | In-house | 1-290 (290) | Show / Hide |
Range on Protein: 704-952
Range on HMM: 1-290/290
Sequence Identity: 32% (95 aa)
FGDVIAAGASGKVYKGIYKGRDVAIKVYS-SENFCFN-IDEFDREVTIMSLIDSD-HPNFTRFYGANK----QNKKYLFHVSELVKSGSLRDLLL-----
|. .| .|..|.||||...| .||||. . | . . ..|| .||..|. . . ||| ....|. . ..... . |.| . |||.|.|
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKL--HYHPNIVHYMGYCMDHQVYPPNMCI-VMEYCPGGSLYDVLHQNNNN
----DKEKPLLYFTQLSIASDIANAMKHLHSIG--VIHRDLKSLNVLITED-----FTAKVIDFGTSRNVD--LAKHMTMN--------LGTSCYMSPEL
....| . ....| ||| .| .||. . .|||||||.|.|.... . .|..|||.|.. . ... ... .|. .|.||.
NNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV
FKG--NGYDETCDVYAFGIVLWEIIARKE------PYENINSWSIPVMVAK---GDRPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICDTL
... . |.| .|||.||||||||. || ||..... .. ||.. . ||.|| .|| ||..||..||.. | .|||| || |
LRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
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| Kinase | DDB0218878e.AA | MLK | 702-952 | 32 | 2.3e-70 | 240.05 | In-house | 1-291 (291) | Show / Hide |
Range on Protein: 702-952 Range on HMM: 1-291/291 Sequence Identity: 32% (95 aa) VIFGDVIAAGASGKVYKGIYKGRD-----VAIKVYSSENFCFNI-----DEFDREVTIMSLIDSDHPN----FTRFYGANKQNKKYLFHVSELVKSGSLR | .| .|..|||.|| ....| ||.| . .. |. . ..|..|. . . . .||| . .|||. .|. . .. |.| . ||| IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRIL--SHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY DLLLD-KEKPL-----------LYFTQL-SIASDIANAMKHLHSIG---VIHRDLKSLNVLITE------DFTAKVIDFGTSRNVDLAKH---MTMNLGT ..| . . |. . .. ..| ..|..| ||| .||||||| |.||.| . |.|. |||||| |. .. |. | || NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR--DWHQMCTNMMSNAGT SCYMSPELF---KGNGYDETCDVYAFGIVLWEIIARKEPYE-NIN-SWSIPVMVAKGDRPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICDTL .|.|| . ... |.| |||. .|.||||...|..||. .. . . ....| ||.|| .|| .||.| || ..|.|||||..| | YAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL |
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| Kinase | DDB0218878e.AA | Dicty4 | 702-954 | 35 | 2e-68 | 227.34 | In-house | 1-277 (277) | Show / Hide |
Range on Protein: 702-954 Range on HMM: 1-277/277 Sequence Identity: 35% (100 aa) VIFGDVIAAGASGKVYKGIYKGRDVAIKVY--SSENF-CFNIDEFDREVTIMSLIDSDHPNFTRFYGANK---QNKKYLFHVSELVKSGSLRDLLLD--- ... | |. |.||||. .| .||.|. .|| . . || .||.||. | ||| |.|| .. . |.|.. .|.| ||.| INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKI--RHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS ---KEKPLLYFTQLS---IASDIANAMKHLHS-I-GVIHRDLKSLNVLITEDFTAKVIDFGTSR----NVDLAK-HMTMNLGTSCYMSPELFKGNGYDET ....| . . .. .| |.| | .||. . .||||||| | |. .....|| ||| |. |. ||. || |.|.|| ...|.| EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTA-CGTPCWMAPEVMMHQPYNEK CDVYAFGIVLWEIIARKEPYE--NINSWSIPVMVAK-GDRPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICDT--LKK ||| |||||||| |.||| .. . |. . || ||..|| ...||. || |..||||.|| | ADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH |
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| Kinase | DDB0218878e.AA | LISK | 707-952 | 32 | 8.9e-66 | 212.62 | In-house | 1-296 (296) | Show / Hide |
Range on Protein: 707-952 Range on HMM: 1-296/296 Sequence Identity: 32% (97 aa) VIAAGASGKVYKGIYK--GRDVAIKVYSSE----NFCFNIDEFDREVTIMSLIDSDHPNFTRFYGANKQNKKYLFHVSELVKSGSLRDLLLDKEK---PL .| |. |||||| .. |...||| .. | .. ..||| .| .. .||| .|.|. ..|.. |. | |... | |...| |..| || EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNL--RHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPL LYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLIT----EDFTAKVIDFGTSRNVDLAK------------------------------------HMT . ..|| ||| .| ||| ..||||||| |.|. .....||.||| | .| . .|| PWPQRVKIALDIACGMSYLHSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRMT MNLGTSCYMSPELFKGNGYDETCDVYAFGIVLWEIIARKEPYE------NINSWSIPVMVAKGDRPTIPAD-CPSEYSKLIKACWTDKPKKRPSFKEICD . || |.|| .| |||.|||. ||||| |||.|... . . . . . .. .. |. | ||.....| | .||.||||||| . I-CGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKADPDYWPRTPQHDFGLDYEEF---WQKICPDDCPPPFLDLCFDCCKYDPKNRPSFKEIVQ TL .| WL |
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| Kinase | DDB0218878e.AA | Dicty4-Unclassified | 702-952 | 34 | 4.2e-63 | 214.96 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 702-952 Range on HMM: 1-263/263 Sequence Identity: 34% (91 aa) VIFGDVIAAGASGKVYKGIYKGRDVAIKVYSSENFCFN---IDEFDREVTIMSLIDSDHPNFTRFYGANKQN---KKYLFHVSELVKSGSLRDLLL---- . | |. ||.||. ||.|||.| . | | |..| .|| |. .| ||| . ||. | . | |. .| | . IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSI--QHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPS DKEKPLLYFT--QLSIASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTAKVIDFGTSRNVDLAKHMTMNLGTSCYMSPELFKGNGYDETCDVYAFGIVL ....|. . .| ||| | |||. .||||.|| |.|. .| .|. ||| || .| || || ||| .. | ||| ....| EQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMML WEIIARKEPYENIN-SWSIPVMVA-KGDRPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICDTL .| . ||| | . |. |. || || |. ..|||| || . |.|||.. .| . | YELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL |
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| Kinase | DDB0218878e.AA | LISK-DD1 | 707-952 | 34 | 2.7e-56 | 193.35 | In-house | 1-290 (290) | Show / Hide |
Range on Protein: 707-952 Range on HMM: 1-290/290 Sequence Identity: 34% (101 aa) VIAAGASGKVYKGIYKGRDVAIKVYSSENFCFNIDEF----DREVTIMS-LIDSDHPNFTRFYGANKQ------------NKKYLFHVSELVKSGSLRDL | |. |||||| | | .||||. .. .| ... .||. . |.. ||| .|.|. . |. |. | |... | |... EIGKGSFGKVYKGCYFGTPVAIKKIHKQPNDPNDPDYWKFMQREIKMLKNLLNIRHPNIVQFIGICEHPLASPSLVNRLLNESSLYIVTEFIEGGDLHWY LLD------------KEKPLLYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITED----FTAKVIDFGTSRNVDLA------KHMTMNLGTSCYMS |.. . .|. . ..|| ||| || ||| ..||||||| | |. | ..||.||| | .. .|||. || |. LKNTPFDDTPEQYIHHKIPIPWKLRVKIALDIACAMAYLHSKNIIHRDLKSKNILVDENGDSQWRIKVCDFGFARMFEQKKNQQNNRHMTI-CGTDNWMA PELFKGNGYDETCDVYAFGIVLWEIIARKEPYENINSWS------IPVMVAKGDRP-TIPAD--CPSEYSKLIKACWTDKPKKRPSFKEICDTL ||. | ||. |||. ||.|| |.| || | ... | | . .. |. ||.| ||.|...| . | .|. ||||||| .|| PEVILGMSYDWSCDVFSFGMVLLELITRKKPDKRMWQRSPMNCFDIDQEEF---RQQKIPKDNDCPREFMDLCMWCCKYDPNNRPSFKEIVQTL |
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| Kinase | DDB0218878e.AA | Pkinase | 702-952 | 25 | 1.6e-54 | 192.28 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 702-952 Range on HMM: 1-293/293 Sequence Identity: 25% (75 aa) VIFGDVIAAGASGKVYKGIYKGRD--VAIKVYSSENFCFNIDEFDR---EVTIMSLIDSDHPNFTRFYGANKQNKKYLFHVSELVKSG----SLRDLLL- .| .| .|..|.|||.. || ||.|. . .. . |. .| |. || .. ||| |.|.. |... | |.. | .| |.. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN--HPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIST DKEKPL--LYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTA----KVIDFGTSRN--VDLAKHMTMNLGTSCYMSPELFK-GNGYDETCDV ...... . . ... |. .....|| |.||||||. |.|| .. . |..||| .. || ||. ||.||. . |..|. .|. WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM YAFGIVLWEIIARKEPYENI----NSWSIPVMVAKGDRPTIPADCP-----------------------SEYSKLIKACWTDKPKKRPSFKEICDT--L ...|..|.| . .. |. . | . .|... .| .. |.| .| ..|| |.. .|||||....|. . WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | DDB0218878e.AA | LRRK | 779-954 | 31 | 4.6e-54 | 185.94 | In-house | 135-351 (351) | Show / Hide |
Range on Protein: 779-954 Range on HMM: 135-351/351 Sequence Identity: 31% (68 aa) ELVKSGSLRDLLLDKEK--------PLLYFTQLSIASDIANAMKHLHSIG--VIHRDLKSLNVLI---T---------EDFTAKVIDFGTSR--NVDLAK |.. |.| ..| .|.. . ..| || .|| .|..||| .||||||| |.|. . .. .||..|||.|| ... . EYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMG -HMTMNLGTSCYMSPELFKGN---GYDETCDVYAFGIVLWEIIARK-EPYENIN-------SWSIPVMVAKGDRPTIPAD-CPS-----EYSKLIKACWT ... .|. .|.|| ..| |.| |.|.||..|||.. |. |..... | . .| ||||| . || .|..||. ||. VAKGC-VGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQ DKPKKRPSFKEICDTLKK .|||||.| .| ..|. HDPKKRPHFSQIVKRLSQ |
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| Kinase | DDB0218878e.AA | TyrKc | 702-952 | 28 | 6.7e-53 | 182.98 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 702-952 Range on HMM: 1-280/280 Sequence Identity: 28% (83 aa) VIFGDVIAAGASGKVYKGIYKGRDVAIKVYSSENFCFNIDEFDREVTIMSLI--DSDHPNFTRFYGANKQNK------KYLFHVSELVKSGSLRDLLLDK . .|... || |.||||..| ..||.|. .. . .| || ||. . . ||| |.||. | . . |. | |... |.|.| | .. ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA----REDFMREARIMCKLGGH--HPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH EKPLLYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTAKVIDFGTSRNVDLA-------KHMTMNLGTSCY-------MSPELFKGNGYDET .. | . ||.. .||. | .||| ..||||| |.|..|..|.|. ||| ||... . .. . .. |.|| .. . . . RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK CDVYAFGIVLWEIIAR-KEPYEN-----INSWSIPVMVAKGDRPTIPAD--------CPSEYSKLIKACWTDKPKKRPSFKEICDTL ||..||...||| . ..||.. .. . | .|.|. .|.. ||.| ...| || .|..||.|.||.. . SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | DDB0218878e.AA | TAK1 | 704-951 | 30 | 1.4e-52 | 175.94 | In-house | 3-284 (284) | Show / Hide |
Range on Protein: 704-951 Range on HMM: 3-284/284 Sequence Identity: 30% (87 aa) FGDVIAAGASGKVYKGIYKGRDVAIKV-----YSSENFCFNIDEFDREVTIMSLIDSDHPNFTRFYG--ANKQNKKYLFHVSELVKSGSLRDLLLD-KEK . .. .|. | |.| ......|.| |||| . .. ||.. |.. |||| . || | ... .| | | . ||| ..| . | | NEHFVGKGTYGVVCKAKWRNKEIAVKRFEFIKYSSEECE--QKNIEREIMQWSRV--DHPNIIKLYGMYACHRQCQCL--VMEYMDCGSLHNFLHGAKPK PLLYFTQ-LSIASDIANAMKHLHSIG---VIHRDLKSLNVLITEDFTA-KVIDFGTSRNVDLAKHMTMNLGTSCYMSPEL-------------------- . . | . .| . ||| .||||.| .| | .. . |. |||| .|. .|| | || .| || WEYTHAHAMSWMHQCAQGVAYLHSMQPKPQIHRDIKPQNMLLCNKHRTLKICDFGTF--CDMHQMMTCNRGTCRWMAPEVRELFDFKSNRIIINQPTGFQ --FKGNGYDETCDVYAFGIVLWEIIARKEPYENINS----WSIPVMVAKGDR-PTIPA--DCPSEYSKLIKACWTDKPKKRPSFKEICDT |... |.. ||.| .||..||.|.||.||. |.. | ...| | | . ||| ... |.|| | | |||| .|. KVFRCEKYNMKCDIYSWGIIMWEVISRKHPYDHIMNPNSAYRIMWAIHNGNRPPMETNRSDCPKRIEQFMKCCWDDNPEKRPSMQECVKY |
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| Kinase | DDB0218878e.AA | S_TKc | 702-959 | 26 | 2.5e-50 | 174.46 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 702-959
Range on HMM: 1-231/231
Sequence Identity: 26% (72 aa)
VIFGDVIAAGASGKVYKGIYKG--RDVAIKVYSSENFCFNIDEFDREVTIMSLIDSDHPNFTRFYGANKQNKKYLFHVSELVKS--GSLRDLLLDKEKP-
....| || |||||.. |. | ||||. . . . ||. |.. .||| ..|.. ..|. | |.. |.|.|.. .. ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK---HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHG
----LLYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTAKVIDFGTSRNVDLAKHMTMNLGTSCYMSPELFKGNGYDE-TCDVYAFGIVLWE
. . ... |..|....|| |.|||||| |.|..| . |..||| .| . | || ||.||.. ||. ||....|..|.|
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE
IIARKEPYENINSWSIPVMVAKGDRPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICD--TLKKISESL
.... |.. . .| | ..| .|. |.. |.|||. |. . |. . .
MLCGYPPFP-----QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | DDB0218878e.AA | Pkinase_Tyr | 702-952 | 30 | 1.6e-48 | 164.97 | Pfam | 1-270 (270) | Show / Hide |
Range on Protein: 702-952 Range on HMM: 1-270/270 Sequence Identity: 30% (83 aa) VIFGDVIAAGASGKVYKGIYK------GRDVAIKVYSSENFCFN---IDEFDREVTIMSLI-DSDHPNFTRFYGANK-QNKK-YLFHVSELVKSGSLRDL ..|| .. .|| |.||||..| . .||.|. |. ...| ||. ||. . . ||| |.||. | . ... | |... |.|.| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGH--HPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY LLDK---EKPLLYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTAKVIDFGTSRNV-----D-LAKHMTMNLGTSCYMSPELFKGNGYDETC | .. ..|| . |... .||..| .|.|.. ||||| |.|.||....|. ||| .| . ... .. |.|| .. . . . LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK--LPIKWMAPECINYGKFTTKS DVYAFGIVLWEIIA-RKEP-YENINSWSIPVMV-AKGDRPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICDTL ||..||...|||. ..| |... . .. .| | .| .|| | .|.| || .|..||.|.|| | DVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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| Kinase | DDB0218878e.AA | LRRK | 702-751 | 16 | 2.2e-07 | 22.16 | In-house | 82-193 (351) | Show / Hide |
Range on Protein: 702-751 Range on HMM: 82-193/351 Sequence Identity: 16% (18 aa) VIFGDVIAAGASG-KVYKGIYKG----------------------------RDVAIKVYSSE---------------------------------NFCFN .... | |..| .||.....| .||||.. . ..| . LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA IDEFDREVTIMS || .||.||| FREFRHEVWIMS |
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