Gene PakG (Slime mold)

PakG

Species: Slime mold
Alias: PakG, DdisK171, DDB0229411
External Links: DictyBase Link ,
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: PAKL

Sequence

Name Sequence Type Origin Length Description Download
PakG.AA Protein None 1179 None Fasta, JSON
PakG.kin_dom Protein Kinase Domain None 246 None Fasta, JSON

Protein domain

Protein domains of PakG.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PakG.AA PAKL 139-390 71 4.7e-214 717.41 In-house 1-256 (256) Show / Hide 
Range on Protein: 139-390
Range on HMM: 1-256/256
Sequence Identity: 71% (182 aa)

FLIDCILGTGSYGTVYKAIHKDTNFVLAIKSIPIKES-E--EIEKEISILKKCKSQNIVSYFGSGQQG-DNLWILMEYCSANSIRDMLELTEKSLTEKQI
| ..  ||.||||.|||||||||||.||||.|.|||| |  .|||||.||||||..||||||||.||. ...||||.|||..||.||.|...|.|.||||
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESNEIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNEKQI

SVILQQALKGLHYLHQSNIIHRDIKAANILINEDAIVKLADFGVSSQLEDSLRGEASQLVGTPLWMAPEIIKRQNYNNKCDIWSLGITAIEMAESFPPLY
||||||.||||||||..|||||||||||||.|||..||.||||||.||.|...|.|.|..|||.|||||||..||||||||||||||||||||..|||.|
SVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINKQNYNNKCDIWSLGITAIEMADGFPPHY

TMPPTRAMLMIPNKPPPTLSKPHHFSKELNDFIGQCCQKDPEKRPSAIELLTHPFL
.|||.|||.||||.||||.|.|.|.|...|||..|||.||||||.|.|.||.|||.
DMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase PakG.AA STE20 139-390 47 1.2e-150 506.72 In-house 1-288 (288) Show / Hide 
Range on Protein: 139-390
Range on HMM: 1-288/288
Sequence Identity: 47% (138 aa)

FLIDCILGTGSYGTVYKAIHKDTNFV----LAIKSIPIKES-------EEIEKEISILKKCKSQNIVSYFGSGQQG----DNLWILMEYCSANSIRDMLE
. .   .| ||||.||||.||.|. .     ||| .....        |.|.|||||.|.||..|||.|.|| . .    |.|||.||||.. |..|...
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---LTEK-----SLTEKQISVILQQALKGLHYLHQSNIIHRDIKAANILINEDAIVKLADFGVSSQLED----SLRGEASQLVGTPLWMAPEIIKR----
    ..|     ...|.||..|....|.||.|||. .||||||||.|||..||. ||||||||..||..    . ...   .|||| |||||.|..    
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-QNYNNKCDIWSLGITAIEMAESFPPLYTMPPTRAMLMIP--NKPPPTLSK--PHHFSKELNDFIGQCCQKDPEKRPSAIELLTHPFL
 ..|..||||||||||||||||  ||.. |.|.|||.|||  ..|||||..  ||..|.|..||. .| ||||||||.| .||.|||.
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase PakG.AA MST 139-390 53 4.6e-140 447.95 In-house 1-254 (254) Show / Hide 
Range on Protein: 139-390
Range on HMM: 1-254/254
Sequence Identity: 53% (136 aa)

FLIDCILGTGSYGTVYKAIHKDTNFVLAIKSIPIKES-EEIEKEISILKKCKSQNIVSYFGSGQ--QGDNLWILMEYCSANSIRDMLELTEKSLTEKQIS
| |  .|| |||| ||||||| |. ..||| .|. |  .||.|||||.. |||..|| |.||        .|| |||| . |. |.  .| . |.| ||.
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVNEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQQIA

VILQQALKGLHYLHQSNIIHRDIKAANILINEDAIVKLADFGVSSQLEDSLRGEASQLVGTPLWMAPEIIKRQNYNNKCDIWSLGITAIEMAESFPPLYT
.||...|.|| |||.. .|||||||.|||.|..   ||||||||.|| |  . ..  ..||| ||||| |  . |..| ||||||||||||||. ||.  
CILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMA-KRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPYSD

MPPTRAMLMIPNKPPPTLSKPHHFSKELNDFIGQCCQKDPEKRPSAIELLTHPFL
  |.||| ||| |||||...|. .| |.|||. .| ||.||.|..| .|| ||| 
IHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase PakG.AA STE 139-390 35 9.40000000001e-132 444.01 In-house 1-359 (359) Show / Hide 
Range on Protein: 139-390
Range on HMM: 1-359/359
Sequence Identity: 35% (131 aa)

FLIDCILGTGSYGTVYKAIHK------DTNFV---------LAIKSIPI--------------------KESEEIEKEISILKKCK--SQNIVSYFGSGQ
. .  ..| |..||||||...      .|..|          ||| ...                    .| ..|.|||.|.|||.  ..||| |.|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

QG-------DNLWILMEYCSANSIRDMLE---LTEKSLT----------EKQISVILQQALKG-LHYLHQSNIIHRDIKAANILINEDAIVKLADFGVSS
..       |.||| |||... |..|...    . |.|.          |.||..|..| ||| |.|||. .|||||||.||||.     |||.||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QLEDSLR---------------GEASQLVGTPLWMAPEIIKR------QNYNNKCDIWSLGITAIEMAESFPPLYTMPPTRAMLMIPNK-----------
||.||..               ..   .|||| |||||.|..      . |. ||||||||.|.||||.  ||. .|.|.|||.|||..           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----PPPTLSK-----------------PHHFSKELNDFIGQCCQKDPEKRPSAIELLT--HPFL
    |||.|                   ||..|.|..||| .|.||||.|||.| .||   |||.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase PakG.AA YSK 139-390 45 6.9e-114 344.37 In-house 1-257 (257) Show / Hide 
Range on Protein: 139-390
Range on HMM: 1-257/257
Sequence Identity: 45% (117 aa)

FLIDCILGTGSYGTVYKAIHKDTNFVLAIKSIPIKESEE----IEKEISILKKCKSQNIVSYFGSGQQGDNLWILMEYCSANSIRDMLEL-TEKSLTEKQ
| .    | ||.| |||.| . |. | ||| |   ..|.    | .|| .|  |.|..|  |.||  ..  ||| ||||   |..| .      .. ||.
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKY

ISVILQQALKGLHYLHQSNIIHRDIKAANILINEDAIVKLADFGVSSQLE-DSLRGEASQLVGTPLWMAPEIIKR--QNYNNKCDIWSLGITAIEMAESF
|..||   |||| |||. . |||||||||.|..|.  |||.||||..|.   ... .    |||| |||||.|.     |. | |||||||||.|||   
IAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNT--FVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGE

PPLYTMPPTRAMLMIPNKPPPTLSKPHHFSKELNDFIGQCCQKDPEKRPSAIELLTHPFL
||.. . | |.|  || ..||.|.. ...|| . .|.  |  ||||.|||| ||| | | 
PPYCDYHPMRVMFLIPKNNPPKLEG-RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase PakG.AA S_TKc 139-390 34 4e-95 323.23 SMART 1-231 (231) Show / Hide 
Range on Protein: 139-390
Range on HMM: 1-231/231
Sequence Identity: 34% (92 aa)

FLIDCILGTGSYGTVYKAIHKDTNFVLAIKSIPIKESEEIEKEISILKKCKSQNIVSYFGSGQQGDNLWILMEYCSA--NSIRDMLELTEKS-----LTE
. |  ..| |..|.|||..||.|. . ||| |.    | |..||.|||| .  ||| .... |  |.|.. ||||.    . .|...   .      ..|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE

KQISVILQQALKGLHYLHQSNIIHRDIKAANILINEDAIVKLADFGVSSQLEDSLRGEASQLVGTPLWMAPEIIKRQNYNN-KCDIWSLGITAIEMAESF
 ..  ...| ...| |.|. .|||||.| .|||..|   .|..|||.. ||        . ..||| .||||..    |.  |||.||.|.. .||.   
-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY

PPLYTMPPTRAMLMIPNKPPPTLSKPHHFSKELNDFIGQCCQKDPEKRPSAIELLT-------HPFL
|| .      .|. .              |.|. ||| .|.||||||||.| |.|.       ||..
PPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PakG.AA PAKA 139-390 40 1.6e-90 307.08 In-house 1-260 (260) Show / Hide 
Range on Protein: 139-390
Range on HMM: 1-260/260
Sequence Identity: 40% (105 aa)

FLIDCILGTGSYGTVYKAIHKDTNFV--LAIKSIPIKESEEIEK---EISILKKCKSQNIVSYFGSGQQGDNLWILMEYCSANSIRDMLELTEK----SL
.     .| |. |.||.|. . ||     ||| . .|.   .|.   ||...|.|| .||| |  |    | ||. ||| .. .  | .. ...     .
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNYM

TEKQISVILQQALKGLHYLHQSNIIHRDIKAANILINEDAIVKLADFGVSSQLEDSLRGEASQLVGTPLWMAPEIIKRQNYNNKCDIWSLGITAIEMAES
.|.||. .... |.||...|. ..||||||  |||.. |. ||..|||   ||... .  ... |||| |||||.|.|..|. | ||||||| ||||.|.
DEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTM-VGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEG

FPPLYTMPPTRAMLMIPNKPPPTLSKPHHFSKELNDFIGQCCQKDPEKRPSAIELLTHPFL
 ||   .|| |||  | ..  | .  |. .|.|..||  .| ..|...|.|| |||.||||
EPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase PakG.AA STE11 139-390 35 1.2e-86 294.21 In-house 1-303 (303) Show / Hide 
Range on Protein: 139-390
Range on HMM: 1-303/303
Sequence Identity: 35% (108 aa)

FLIDCILGTGSYGTVYKAIHKDTNFVLAIKSIPIKESE-----------E------IEKEISILKKCKSQNIVSYFGSGQ---QGDNLWILMEYCSANSI
.    |.|.|..|||||.. .||. ..|.| |.|. ..           .      |..||...|. . .||| |.|. .   | |.. | ||||.  |.
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

RDMLELTEKS--LTEKQISVILQQALKGLHYLHQSNIIHRDIKAANILINEDAI-VKLADFGVSSQLEDSLRGEAS---------QLVGTPL--------
..||..      ..|. |..  .| |.||.|||. .|||||||.||||.. | . .|||||| . .|. ...  ..         .. |||         
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPM

WMAPEIIKRQN---YNNKCDIWSLGITAIEMAESFPPLYTMP--PTRAMLMIPNKPPPTLSKPHHFS------KELNDFIGQCCQKDPEKRPSAIELLTH
|||||.||..    |  |.|||||| | ||||   || . .   .  ||  |  .  |.   | |.|       |..||. .|...||.|||.| .|| |
WMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQH

PFL
||.
PFI
Kinase PakG.AA Ste20-DD1 139-390 43 1e-82 281.12 In-house 1-268 (268) Show / Hide 
Range on Protein: 139-390
Range on HMM: 1-268/268
Sequence Identity: 43% (117 aa)

FLIDCILGTGSYGTVYKA-------IHKDTNFVLAIKSIPIKE-----SEEIEKEISILKKC-KSQNIVSYFGSGQQGDNLWILMEYCSANSIRDMLELT
| |  . | ||.|.|          .    | | |.| . .            ||| |||   .   || | |      .| | ||||   || | ... 
FQIVEVIGQGSFGVVCTCRWMKKKDRNTNNNRVIACKFVEMNADDVEENSNLKKEIDILKNTMDCPYIVKYHGCYIKENMLMIVMEYCDGGSILDIMQMC

EKSLTEKQISVILQQALKGLHYLHQSNIIHRDIKAANILINEDAIVKLADFGVSSQLE-DSLRGEASQLVGTPLWMAPEIIKR----QNYNNKCDIWSLG
 | |.| ||  |. |  ||| |||   |.|||||| |.|.|.    ||||||||  ..    .      .| | ||.||||      | |  | ||||||
SKRLIEEQIAAICYQIVKGLVYLHSNRITHRDIKAGNVLVNKEGQPKLADFGVSTIAVNQGFKMNT--VIGSPYWMSPEIIMPPKGSQGYDQKADIWSLG

ITAIEMAESFPPLYTMPPTRAMLMIPNKPPPTLSKPHHFSKELNDFIGQCCQKDPEKRPSAIELLTHPFL
||||||||| ||.. ..| |    || ..||||  |   | | |||| ||  ..|.||||| .|| ||| 
ITAIEMAESKPPRFNVNPVRVIFVIPHQQPPTLKIPSNWSPEFNDFIKQCLNMNPDKRPSAQQLLNHPFI
Kinase PakG.AA KHS 139-390 42 1e-82 278.03 In-house 1-258 (258) Show / Hide 
Range on Protein: 139-390
Range on HMM: 1-258/258
Sequence Identity: 42% (110 aa)

FLIDCILGTGSYGTVYKAIHKDTNFVLAIKSIPIKESEE---IEKEISILKKCKSQNIVSYFGSGQQGDNLWILMEYCSANSIRDMLELTEKSLTEKQIS
. .   .|.| || |||| .. .. . |.| | .  ...   | .|| ..|.|.  |||.||||  . | ||| |||| . |. |. ..|  .|.| ||.
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTG-PLSELQIA

VILQQALKGLHYLHQSNIIHRDIKAANILINEDAIVKLADFGVSSQLEDSLRGEASQLVGTPLWMAPEII---KRQNYNNKCDIWSLGITAIEMAESFPP
 . ...|.||||||.   .||||| ||||....  |||||||||.|.  ..    |  .||| |||||.    ..  ||. ||||..||||||.||  ||
YVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKS-FIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPP

LYTMPPTRAMLMIP--NKPPPTLSKPHHFSKELNDFIGQCCQKDPEKRPSAIELLTHPFL
.. . | ||....   |  ||.|   |..|.   .|. ..  |.| |||.|  ||.|||.
MFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase PakG.AA MSN 139-390 42 1.3e-80 265.93 In-house 1-265 (265) Show / Hide 
Range on Protein: 139-390
Range on HMM: 1-265/265
Sequence Identity: 42% (115 aa)

FLIDCILGTGSYGTVYKAIHKDTNFVLAIKSIPIK--ESEEIEKEISILKK-CKSQNIVSYFG-------SGQQGDNLWILMEYCSANSIRDMLELT-EK
| .. ..| | || ||| .|. |  . ||| . ..  | ||| .|| .|||    .||..|.|       .|.. . ||. ||.|.| |. |..  | ..
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVREDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHD-HQLWMVMEFCGAGSVTDLVKMTKGQ

SLTEKQISVILQQALKGLHYLHQSNIIHRDIKAANILINEDAIVKLADFGVSSQLEDSLRGEASQLVGTPLWMAPEIIK-----RQNYNNKCDIWSLGIT
|| |  |  |    |.|| .|||. .||||||  |.|. ..| ||| ||||| || |   |     .||| |||||.|.     .  | .. |.||.|||
SLKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQL-DRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSVGIT

AIEMAESFPPLYTMPPTRAMLMIPNKPPPTLSKPHHFSKELNDFIGQCCQKDPEKRPSAIELLTHPFL
||||||. |||  | | ||...|| .|||.| | . .||  ..|. .|  |. ..||.. ..| |||.
AIEMAEGQPPLCDMHPMRALFLIPRNPPPKL-KSKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase PakG.AA Pkinase 139-390 29 2.2e-80 278.13 Pfam 1-293 (293) Show / Hide 
Range on Protein: 139-390
Range on HMM: 1-293/293
Sequence Identity: 29% (88 aa)

FLIDCILGTGSYGTVYKAIHKDTNFVLAIKSIPIKESEEIEK-------EISILKKCKSQNIVSYFGSGQQGDNLWILMEYCSAN----SIRDMLE-LTE
. |  ..| ||.|.|||..||.|. . |.| |. .. .. ..       ||.|.|.... ||| .... . .|.... ||||       .  |...   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KSL--TEKQISVILQQALKGLHYLHQSNIIHRDIKAANILINEDAIV----KLADFGVSSQLEDSLRGEASQLVGTPLWMAPEIIK-RQNYNNKCDIWSL
...  .|...  .. | |.|| |.|. .|||||.| .||||...  .    |..|||.. |..    . .. ..||| .||||.|. .| |  |.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GITAIEMAESFPPLYTM----PPTRAMLMIPNKPPPTLSKPHHFS---------------------KELNDFIGQCCQKDPEKRPSAIELLTHPFL
|.. .||.   || .      .  . | || .. .| |. .   .                     .|. |||  |..|||.|||.| ..| ||..
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase PakG.AA Pkinase_Tyr 139-390 28 1.6e-39 134.5 Pfam 1-270 (270) Show / Hide 
Range on Protein: 139-390
Range on HMM: 1-270/270
Sequence Identity: 28% (79 aa)

FLIDCILGTGSYGTVYKAIHK----DTNFVLAIKSI----PIKE--SEEIEKEISILKKC-KSQNIVSYFGSGQ-QGDN--LWILMEYCSANSIRDMLEL
  ..  || |..|.|||.. |    .|.   |.|..      ..  .|.  .|..|.|.  . .|||.. |    ||.   ..| |||.   . .| |  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

T---EKSLTEKQISVILQQALKGLHYLHQSNIIHRDIKAANILINEDAIVKLADFGVSSQLEDSLRGEA-SQLVGTPL---WMAPEIIKRQNYNNKCDIW
    ...|| |..  . .|  ||. ||.. |.||||. | |.|..|. .|| .||| .  .     ..   .  |..|   ||||| |.   .. | |.|
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI--YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SLGITAIEMAE-SFPP-LYTMPPTRAMLMI-PNKPPPTLSKPHHFSKELNDFIGQCCQKDPEKRPSAIELLTHPFL
| |..  |.      |  . |.... . .|  .     . .|.. ..|. | . || ..|||.||.  |.  | .|
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR--MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL
Kinase PakG.AA TyrKc 139-390 27 6.4e-30 106.63 SMART 1-280 (280) Show / Hide 
Range on Protein: 139-390
Range on HMM: 1-280/280
Sequence Identity: 27% (78 aa)

FLIDCILGTGSYGTVYKAIHKDTNFVLAIKSIP-IKESEEIEKEISILKKC--KSQNIVSYFGSGQQG-------DNLWILMEYCSANSIRDMLELTEKS
   . .|| | .|.|||.. |      |.|..   .  |.. .|..|..|   . .|||  .|   |.       . |.|.|||..  . .| |  ... 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LTEKQISVILQQALKGLHYLHQSNIIHRDIKAANILINEDAIVKLADFGVSSQLEDS-LRGEASQLV------GTP--L---WMAPEIIKRQNYNNKCDI
|. |.   .  |. .|  |||. |.||||. | |.|..|. .|| .||| |  ..|   .||...        |.   |   ||||| |.   .. | |.
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSLGITAIEMAES-FPPLYT-----MPPTRAMLMIPNKPPPTLSKPHH--------FSKELNDFIGQCCQKDPEKRPSAIELLTHPFL
|| |..  |.     .| .      |......  . .     . .|..         ..|. . . ||.. |||.||.  |.  | ..
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQG--YRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
PBD PakG.AA PBD 110-126 44 1.1e-05 22.76 Pfam 1-18 (60) Show / Hide 
Range on Protein: 110-126
Range on HMM: 1-18/60
Sequence Identity: 44% (8 aa)

NIGTP-FNVQHKVHVDFD
 |.|| .|..|..|| .|
MISTPLTNFKHTMHVGWD
PBD PakG.AA PBD 111-143 34 1.4e-05 25.78 SMART 1-38 (38) Show / Hide 
Range on Protein: 111-143
Range on HMM: 1-38/38
Sequence Identity: 34% (13 aa)

IGTPF-NVQHKVHVD-FDY---KWSGCQDLEQVFLIDC
|.||. |..|.|||  .|    .  | . . |. |  |
ISTPTGNFKHIVHVGPWDGQTGEFTGLPHQWQHLLKHC