Gene PakA (Slime mold)

PakA

Species: Slime mold
Alias: dpak1, DDB0191313, PakA, DdisK165
External Links: DictyBase Link ,
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: PAKA

Sequence

Name Sequence Type Origin Length Description Download
PakA.AA Protein None 1197 None Fasta, JSON
PakA.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of PakA.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PBD PakA.AA PBD 816-872 40 2e-22 80.78 Pfam 1-60 (60) Show / Hide 
Range on Protein: 816-872
Range on HMM: 1-60/60
Sequence Identity: 40% (24 aa)

RVGTP-FNVKHDVHVNFNADTG-FEGLPKEWEVLIKSN-FQEPEVMQHPEEVLDVVKFHA
 ..|| .|.|| .||.....|| |.|.|.||. | .|.  ..|| ...|. |.|||.|. 
MISTPLTNFKHTMHVGWDGQTGFFTGMPPEWQKLLQSSGISKPEQKHNPQAVFDVVQFYQ
PBD PakA.AA PBD 817-851 39 1.5e-14 55.55 SMART 1-38 (38) Show / Hide 
Range on Protein: 817-851
Range on HMM: 1-38/38
Sequence Identity: 39% (15 aa)

VGTPF-NVKHDVHVN-FNA-DTGFEGLPKEWEVLIKSN
..||. |.|| |||. ... ...|.|||..|..|.|..
ISTPTGNFKHIVHVGPWDGQTGEFTGLPHQWQHLLKHC
Kinase PakA.AA PAKA 911-1164 60 4.90000000001e-186 624.34 In-house 1-260 (260) Show / Hide 
Range on Protein: 911-1164
Range on HMM: 1-260/260
Sequence Identity: 60% (157 aa)

YYNINKIGEGGAGEVFEAINSRTNQT--IAIKKMKLKAQNLK-TVINEIGMMKNSNHENIVQYIDSYIVADELWVAMEFMSGGCLTEVLDQYRDIQLN--
|....|||.|..|||..|.|..|||.  .|||.|..|.|. | ..||||..||...|.|||.|||||.| |||||.||.|.|||||.|..|...||.|  
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNYM

-ESQIAFVCQEVLRGLEYIHKFNRIHRDIKSDNILIGANGEIKLADFGYAAQLTQIRQERNSVVGTPYWMAPELIRGNNYDFKVDVWSLGIMTREMAEGE
 |.|||.||.|.|.|||.||. .||||||||||||.|..|..|..|||..||||| .|.||..||||||||||.||...|| |||.||||||..||.|||
DEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEGE

PPYLEFPPLRALFLLTTQGLPPIRDAHKWSKEFNDFLALCLEKDTEKRASSSSLLHHPFL
||||..|||||..|..|.| |.|.|..|||.||.|||..||..|...|||...|||||||
PPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase PakA.AA STE20 911-1164 45 7.2e-155 520.8 In-house 1-288 (288) Show / Hide 
Range on Protein: 911-1164
Range on HMM: 1-288/288
Sequence Identity: 45% (130 aa)

YYNINKIGEGGAGEVFEAINSRTNQT----IAIKKMKLKAQN-----LKTVINEIGMMKNSNHENIVQYIDSYIVA----DELWVAMEFMSGGCLTEVLD
| .. |||.|. |.|. |.. .|..     .|||||.|. ..     ......|| .||...|.|||.|..||..     ||||..||...||.||....
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

QYRDIQ-------LNESQIAFVCQEVLRGLEYIHKFNRIHRDIKSDNILIGANGEIKLADFGYAAQLTQ----IRQ-ERNSVVGTPYWMAPELIRG----
..  ..       .||.|||..|.|||.||.|.|. ..||||||.||||.. .||.||||||..||||.     .| .||..||||||||||.|..    
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-NNYDFKVDVWSLGIMTREMAEGEPPYLEFPPLRALFLLT--TQGLPPIRD--AHKWSKEFNDFLALCLEKDTEKRASSSSLLHHPFL
 ..||.|.|.|||||.. |||||||||....|.||.|. .  . . |. .|   ||||.||.||...||.|| |||...| ||.|||.
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase PakA.AA STE 911-1164 32 2.6e-126 425.91 In-house 1-359 (359) Show / Hide 
Range on Protein: 911-1164
Range on HMM: 1-359/359
Sequence Identity: 32% (119 aa)

YYNINKIGEGGAGEVFEAINS------RTNQT---------IAIKKMKLKAQN------------------LKTVINEIGMMKNSN--HENIVQYIDSYI
. .| |||.|. |.|. |.|       .|...         .|||.|.|. .|                  .. ...|| .||..|  |.|||.|...|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VA-------DELWVAMEFMSGGCLTEVLDQYRDIQLN------------ESQIAFVCQEVLRG-LEYIHKFNRIHRDIKSDNILIGANGEIKLADFGYAA
.        ||||..||.|.||.|.......  .. .            |||||..|...|.| |.|.|. ..||||||..|||.     .||.||| ..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QLTQI----------------RQERNSVVGTPYWMAPELIRG------NNYDFKVDVWSLGIMTREMAEGEPPYLEFPPLRALFLLTTQ-----------
|||..                 |.||..|||| ||||| |..      . ||.|.|.||||..  |||.|.||. ...|.||.|. ..            
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----GLPPIRDA-----------------HKWSKEFNDFLALCLEKDTEKRASSSSLLH--HPFL
    . ||. |                  ||||.||.||...||.|| .||...| ||.  |||.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase PakA.AA MST 911-1164 42 1.5e-104 333.22 In-house 1-254 (254) Show / Hide 
Range on Protein: 911-1164
Range on HMM: 1-254/254
Sequence Identity: 42% (109 aa)

YYNINKIGEGGAGEVFEAINSRTNQTIAIKKMKLKAQNLKTVINEIGMMKNSNHENIVQYIDSYI--VADELWVAMEFMSGGCLTEVLDQYRDIQLNESQ
.  . |.|.|  | |. ||.  |..  |||...     |   |.|| .|.. . ..||.| .||.     ..|  ||.  .| .  .    ....||| |
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPV-NEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIM-KITQRTLNEQQ

IAFVCQEVLRGLEYIHKFNRIHRDIKSDNILIGANGEIKLADFGYAAQLTQIRQERNSVVGTPYWMAPELIRGNNYDFKVDVWSLGIMTREMAEGEPPYL
|| ... .|.||.| |.  .||||||. |||.   || |||||| ..|||    .||.|.||||||||| |  . || |.| |||||   |||||.||| 
IACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPYS

EFPPLRALFLLTTQGLPPIRDAHKWSKEFNDFLALCLEKDTEKRASSSSLLHHPFL
.. | ||.|.  .   |  .| ..|| |||||.. || |. |.|...  || ||| 
DIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase PakA.AA YSK 911-1164 40 1.7e-95 288.01 In-house 1-257 (257) Show / Hide 
Range on Protein: 911-1164
Range on HMM: 1-257/257
Sequence Identity: 40% (104 aa)

YYNINKIGEGGAGEVFEAINSRTNQTIAIKKMKLKAQN--LKTVINEIGMMKNSNHENIVQYIDSYIVADELWVAMEFMSGGCLTEVLDQYRDIQLNESQ
.    .|| |  |||. .|. ||....|||   |         .  ||         .| .|. ||     ||. ||.  || .   . .    |. |..
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKY

IAFVCQEVLRGLEYIHKFNRIHRDIKSDNILIGANGEIKLADFGYAAQLTQIRQERNSVVGTPYWMAPELIRG--NNYDFKVDVWSLGIMTREMAEGEPP
||..  |.| ||.|.|. . ||||||. |.|. ..|..||.||| |.|.|.  . ||  ||||||||||.|      ||||.|.||||| . ||| ||||
IAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPP

YLEFPPLRALFLLTTQGLPPIRDAHKWSKEFNDFLALCLEKDTEKRASSSSLLHHPFL
| .  |.|..||.  .  ||    ...|| | .| ..||.|| |.| | . || | | 
YCDYHPMRVMFLIPKN-NPPKLEGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase PakA.AA S_TKc 911-1164 30 2.3e-94 320.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 911-1164
Range on HMM: 1-231/231
Sequence Identity: 30% (82 aa)

YYNINKIGEGGAGEVFEAINSRTNQTIAIKKMKLKAQNLKTVINEIGMMKNSNHENIVQYIDSYIVADELWVAMEFMSG--GCLTEVLDQYRD----IQL
|  ..|||.|. |.|. ... .|..  |||..|      .....|| ..|. .|.|||...|..   |.|.. ||...|  | | .......      ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

NESQIAFVCQEVLRGLEYIHKFNRIHRDIKSDNILIGANGEIKLADFGYAAQLTQIRQERNSVVGTPYWMAPELIRGNNYDF-KVDVWSLGIMTREMAEG
.| ...|........|||.|. . ||||.| .|||.    .||..||| |.||       ....|||..||||..    |.. |.|.||.|..  ||. |
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

EPPYLEFPPLRALFLLTTQGLPPIRDAHKWSKEFNDFLALCLEKDTEKRASSSSLLH-------HPFL
.||.     . ..| .              |.|. ||.  ||.|| ||| .   .|.       ||..
YPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PakA.AA PAKB 913-1164 47 3e-94 319.43 In-house 3-252 (252) Show / Hide 
Range on Protein: 913-1164
Range on HMM: 3-252/252
Sequence Identity: 47% (119 aa)

NINKIGEGGAGEVFEAINSRTNQTIAIKKMKL-KAQNLKTVINEIGMMKNSNHENIVQYIDSYIVADELWVAMEFMSGGCLTEVLDQYRDIQLNESQIAF
| .|||||  | |  | .  | . .|.||| | | |      ||.  | .  |.|||.  .|| | ||||| |||| || || .  . |   .|| ||| 
NYVKIGEGSTGIVCIATEKHTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYQHPNIVEMYSSYLVGDELWVVMEFMEGGALTDIVTHTR---MNEEQIAT

VCQEVLRGLEYIHKFNRIHRDIKSDNILIGANGEIKLADFGYAAQLTQIRQERNSVVGTPYWMAPELIRGNNYDFKVDVWSLGIMTREMAEGEPPYLEFP
||. ||. |.| |    |||||||| ||  . | .|| |||. ||. .    | | ||||||||||.|    |. .||.||||||  || .|||||   |
VCRQVLQALAYLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMVDGEPPYFNEP

PLRALFLLTTQGLPPIRDAHKWSKEFNDFLALCLEKDTEKRASSSSLLHHPFL
||.|.  .  .  | ....|| | .  .||  .| .| ..|..   ||.||||
PLQAMKRIRDMHPPRLKNHHKVSPRLREFLDRMLVRDPNQRWTAQELLRHPFL
Kinase PakA.AA FRAY 911-1164 37 1.9e-85 265.35 In-house 1-277 (277) Show / Hide 
Range on Protein: 911-1164
Range on HMM: 1-277/277
Sequence Identity: 37% (103 aa)

YYNINKIGEGGAGEVFEAINSRTNQTIAIKKMKLKAQN---LKTVINEIGMMKNSNHENIVQYIDSYIVADELWVAMEFMSGGCLTEVLD-QYRDIQ---
|  .  ||||. . |..|.    .  .|||   |   .   .. .| ||  |   .|.|.|.|  |..| .|||. | . ..| .  ..   .....   
YELQEVIGEGATAVVHKAYCIPRQENCAIKRINLEKCQNTSMDELIKEIQAMCQCHHPNVVHYHTSFVVNEELWLVMRYLECGSCLDIMKFKMPQGEPHK

---LNESQIAFVCQEVLRGLEYIHKFNRIHRDIKSDNILIGANGEIKLADFGYAAQLTQ----IRQ-ERNSVVGTPYWMAPELIRGNN-YDFKVDVWSLG
   . |  || .  |||.||.| ||  .||||||..||||| .| | .||||  | | .     |.  |   |||| ||||| .   . ||||.|.||.|
QGVFDEHVIATILKEVLKGLCYFHKNGQIHRDIKAGNILIGEDGTIQIADFGVSAWLATGGDLSRCCVRHTFVGTPCWMAPEVMEQVHGYDFKADIWSFG

IMTREMAEGEPPYLEFPPLRALFLLTTQGLPPI----RDAH----KWSKEFNDFLALCLEKDTEKRASSSSLLHHPFL
|   |.| | .|| ..||   | .|| |. ||      |      |... | . .  || || .||   | || | | 
ITAIELATGKAPYHKYPPMKVL-MLTLQNDPPSLETDEDDKDMYKKYGHSFKKMIEKCLQKDPSKRPTASELLKHKFF
Kinase PakA.AA KHS 911-1164 40 3.7e-85 286.39 In-house 1-258 (258) Show / Hide 
Range on Protein: 911-1164
Range on HMM: 1-258/258
Sequence Identity: 40% (106 aa)

YYNINKIGEGGAGEVFEAINSRTNQTIAIKKMKLKAQ-NLKTVINEIGMMKNSNHENIVQYIDSYIVADELWVAMEFMSGGCLTEVLDQYRDIQLNESQI
|  . ..| |  |.|. | . ....  |.| .|. .. .....  || |||.  | ||| |. ||.  | ||..||.  || | ..       .|.| ||
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVT--GPLSELQI

AFVCQEVLRGLEYIHKFNRIHRDIKSDNILIGANGEIKLADFGYAAQLTQIRQERNSVVGTPYWMAPELI---RGNNYDFKVDVWSLGIMTREMAEGEPP
|.||.|.|.||.|.|   ..|||||  |||.  .|..|||||| .||.|.    | | .|||||||||     |   |.   |.|..||   |.||  ||
AYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPP

YLEFPPLRALFLLTTQGLPP--IRDAHKWSKEFNDFLALCLEKDTEKRASSSSLLHHPFL
  .  |.|||||.|  .  |  ..| ||||. | .|. ..| |.  || ... ||.|||.
MFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase PakA.AA MKC 911-1164 38 2.8e-83 282.97 In-house 1-260 (260) Show / Hide 
Range on Protein: 911-1164
Range on HMM: 1-260/260
Sequence Identity: 38% (102 aa)

YYNINKIGEGGAGEVFEAIN-----SRTNQTIAIKKMKLK-AQNLKTVINEIGMMKNSNHENIVQYIDSYIVAD-ELWVAMEFMSGGCLTEVLDQ-YRDI
| .  ..| || | |. | .        .. .|||||  . .   ... ||||  .  || ||| |. |... | |.| .||||.|| |.|   . .   
YKFLHQVGKGGFGTVYCAKYNNPHSTYDKCRVAIKKMPHVTKKHQRNNLNEIGFLNYCNHPNIVKYHCSHMKHDDEIWMVMEFMQGGTLEEASQNSH---

QLNESQIAFVCQEVLRGLEYIHKFNRIHRDIKSDNILIGANGEIKLADFGYAAQLTQIRQERNSVVGTPYWMAPELIRGNNYDFKVDVWSLGIMTREMAE
  .||.||.|| |.| ||.| |. | .|||.|| || .   ||||| |||  . ..  ..| .  .| |.||.|| |... .   .| ||.||   ||| 
KFCESCIAYVCKEMLQGLMYLHEHNIVHRDLKSANIMMNTDGEIKLIDFGLCIDVSHEKEEIH-MCGSPFWMSPEMIQQKQHSYPCDIWSFGICLLEMAN

GEPPYLEFPPLRALFLLTTQGLPP---IRDAHKWSKEFNDFLALCLEKDTEKRASSSSLLHHPFL
|.||. .  .. | |.  | |.       | ..|| .| ||| .||. | .||.... || |||.
GRPPHHK-SRMKAMFMVATNGCKFPKEFDDPCHWSDCFHDFLWQCLQMDPHKRPTAEQLLKHPFI
Kinase PakA.AA PAKL 916-1164 41 1.6e-79 270.47 In-house 6-256 (256) Show / Hide 
Range on Protein: 916-1164
Range on HMM: 6-256/256
Sequence Identity: 41% (105 aa)

KIGEGGAGEVFEAINSRTNQTIAIKKMKLKAQ-NLKTVINEIGMMKNSNHENIVQYIDSYIVA-DELWVAMEFMSGGCLTEVLDQYRDIQLNESQIAFVC
| |.|. | |. ||   || ..||| . .|     | . .|| . |. .  ||| |  |     ...|. |.. | |    ..    .  ||| ||... 
KLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESNEIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKT-LNEKQISVIL

QEVLRGLEYIHKFNRIHRDIKSDNILIGANGEIKLADFGYAAQLTQIRQ-ERNSVVGTPYWMAPELIRGNNYDFKVDVWSLGIMTREMAEGEPPYLEFPP
| .|.|| | |  | ||||||. |||.   . .|.||||   ||      . |. .||||||||| |   ||. |.|.|||||   |||.|.||  . ||
QQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINKQNYNNKCDIWSLGITAIEMADGFPPHYDMPP

LRALFLLTTQGLPPIRDAHKWSKEFNDFLALCLEKDTEKRASSSSLLHHPFL
 ||.        |   . ..||..|||||| |. || |||.| . || |||.
MRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase PakA.AA Pkinase 911-1164 31 8.2e-79 272.94 Pfam 1-293 (293) Show / Hide 
Range on Protein: 911-1164
Range on HMM: 1-293/293
Sequence Identity: 31% (94 aa)

YYNINKIGEGGAGEVFEAINSRTNQTIAIKKMKLKAQNLKTVIN-----EIGMMKNSNHENIVQYIDSYIVADELWVAMEFMSGGCLTEVLDQY------
|  . |||.|. |.|.....  |... |.|..|.. .. .  ..     || .||. ||.|||...|..   |.... ||.. || |. |.| .      
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGG-LY-VMDLFDYISTW

RDIQL--NESQIAFVCQEVLRGLEYIHKFNRIHRDIKSDNILIGANGEI----KLADFGYAAQL-TQIRQERNSVVGTPYWMAPELIR-GNNYDFKVDVW
|.  .   | .. |.. ..||||||.|. . ||||.|..||||  ||.|    |..||| |.|. .   .  ....|||..||||.|| |. |. |||.|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SLGIMTREMAEGEPPYLEF----PPLRALFLLTTQGLPPIRDAHKWS---------------------KEFNDFLALCLEKDTEKRASSSSLLHHPFL
|.|..  ||. |.||. .     . .. ....   . ||..    |.                     .|. ||.  ||.|| .|| .   .|.||..
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase PakA.AA TyrKc 911-1164 23 4.4e-25 90.56 SMART 1-280 (280) Show / Hide 
Range on Protein: 911-1164
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

YYNINKIGEGGAGEVFEAINSRTNQTIAIKKMKLKAQNLKTVINEIGMMKNS--NHENIVQYIDSYIVA-------DELWVAMEFMSGGCLTEVLDQYRD
   . |.|||  |||.... .   .. |.|..|  |  ..  ..|. .|..   .|.|||. .   .         . |.. ||.|..|.| . |  .|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

IQLNESQIAFVCQEVLRGLEYIHKFNRIHRDIKSDNILIGANGEIKLADFGYAAQLTQI-----RQERNSV---VGTP-----YWMAPELIRGNNYDFKV
  |. ..    |  . .| ||.|. | ||||.   |.|.|.|. .| .||| .  ..       ...  ..    |.       ||||| |. . . .| 
K-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DVWSLGIMTREMAE-GEPPYLE-----FPPLRALFLLTTQGLPPIRDAHK------WSKEFNDFLALCLEKDTEKRASSSSLLHHPFL
|||| |..  |.   |..|| .      .. ... .. . . .|. . .        ..|  .    | . | |.| . | .  | ..
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase PakA.AA Pkinase_Tyr 911-1052 25 5.6e-17 58.13 Pfam 95-250 (270) Show / Hide 
Range on Protein: 911-1052
Range on HMM: 95-250/270
Sequence Identity: 25% (40 aa)

YYNINKIGEGGAGEVFEAINS----RTNQTIAIKKM--KLKAQN--LKTVINEIGMMKNS-NHENIVQYIDSYI-VADE--LWVAMEFMSGGCLTEVLDQ
   . |.|||  |||....       |... |.|..  .   ..  ..  ..|. .||.  .|.|||...   .   .   ... ||.| .|.| . | .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

Y--RDIQLNESQIAFVCQEVLRGLEYIHKFNRIHRDIKSDNILIGANGEIKLADFG
    . .|. ...   |... .|.|| .  | ||||.   |.|.. |. .| .|||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase PakA.AA Pkinase_Tyr 1073-1123 33 6e-06 20.73 Pfam 180-232 (270) Show / Hide 
Range on Protein: 1073-1123
Range on HMM: 180-232/270
Sequence Identity: 33% (18 aa)

WMAPELIRGNNYDFKVDVWSLGIMTREMAE-GEPP-YLEFPPLRALFLLTTQG
||||| |. . .  | |||| |.   |.   || | | . .. . . ... .|
WMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG