Gene FNIPK-D (Slime mold)

FNIPK-D

Species: Slime mold
Alias: DDB0231208, fnkD, FNIPK-D, DdisK150
External Links: DictyBase Link ,
Annotation:

Classification

Group: STE
Family: Dicty3
Subfamily: FNIPK

Sequence

Name Sequence Type Origin Length Description Download
FNIPK-D.AA Protein None 723 None Fasta, JSON
FNIPK-D.kin_dom Protein Kinase Domain None 148 None Fasta, JSON

Protein domain

Protein domains of FNIPK-D.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase FNIPK-D.AA FNIPK 33-185 39 3.4e-71 237.83 In-house 1-171 (425) Show / Hide 
Range on Protein: 33-185
Range on HMM: 1-171/425
Sequence Identity: 39% (69 aa)

WEIITQLESNEQFTVYMSKKLKGPNFTNNRFGLCTVKKIKSQ----YFNENEILNHIKLRDNK---------YVLKYYGCGKDN-NQDVYIYLEFIEYSI
|||| .| |..  .|   ||. .  |. ||. .|  |.||      ||..|||..||||||.|         ...||||...|. ....|||.|.|...|
WEIISTLKSGNFGRVCKAKKINC-QFNGNRVNFCIIKIIKKKDKYYYFKWNEIEIHIKLRDCKEILEKIKHICIMKYYGYCCDEIDHNFYIYMEYIDGYI

PISKVKLIPNDSSIDNFNNVSNTIIELVTCKLVESLNCIHKDN-KIVHGNIKGENILLVNDES-----EYGFS
|||.||.. |.......|.....||....|.||.||||||... .|.|..||..||..||||.     .|..|
PISYVKTN-NLLKKHPHNQFPEDIISRCMCDLVKSLNCIHENGRHIIHRDIKCDNIMIVNDEFHSCDFDYNCS
Kinase FNIPK-D.AA Dicty3 67-247 21 3.1e-52 170.69 In-house 20-335 (351) Show / Hide 
Range on Protein: 67-247
Range on HMM: 20-335/351
Sequence Identity: 21% (68 aa)

TVKKIKSQYFNENEILNHIKL------RDNK---------YVLKYYG--CGKDNNQ-DVYIYLEFIEYSIPISKVKLIPNDSSIDNFNNVSNTIIELVTC
....||........|.|....      |..|         ...||||  ...|||. ..|||.|.||..||||.||.. |.......|......|. ..|
CIINIKMVDICHIKIINKCDFNEVNNWRHEKIINKKMRHPCIVKYYGACYCCDNNNDNHYIYMEYIEGEIPISFVKTN-NMLKKHKNNRFNEHEISKIIC

KLVESLNCIHKDNKIVHGNIKGENILLVNDES------------------------------EYGFS---------------------------------
.||..||.|||...|.|..||..||.|.|||.                              ..|.|                                 
DLVKTLNYIHKNCHIIHRDIKCDNIMLDNDEQHQCNNNNNKMSSTCRDIQCYYSNEINWKLIDFGLSKNISYYSNNNNNNNYNNNNNNNNNNNNNNNNNN

----------------VKFIN----------------------FSLNIGYEDS----IHLDMFNLGCVLIQMLGCD---CTKDEN-IDFLFS--------
                ||.||                      ....|.....    ...|...|||....|.| .   | .| |   |  .        
NNNNNNNNNNNNTNNNVKIINNNIYSNKQYKQKCYSICGTIHYMAPEIKLNNQCCACRKSDIWSLGCTVWEMVGGNLCHCEQDINEMAFMVNDNKQNIWI

-KIPNHLVEKFKKVISQ
 .||.|. ...|  | .
PQIPDHVSNFCKNFIQH
Kinase FNIPK-D.AA STE 33-191 17 9.1e-17 55.83 In-house 1-191 (359) Show / Hide 
Range on Protein: 33-191
Range on HMM: 1-191/359
Sequence Identity: 17% (36 aa)

WEIITQLESNEQFTVYMSKKLKGPNFT--------NNRFGLCTVKKIK----------------------SQYFNENEILNHIKLRD-NKYVLKYYGCGK
||.| .. .   .|||  .. | .|..        ..   .. .|...                       .   ..||  . |...  ... |||||  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DN------NQDVYIYLEFIEYSIPISKVKLIPNDSSIDNFNN-----VSNTIIELVTCKLVES-LNCIHKDNKIVHGNIKGENILLVNDESEYGFSVKFI
..      .....|..|....    . .|        .|.|.     .. ..|  ... ...  |. .|. . |.|  ||. ||||          || .
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH-IIHRDIKPANILL----------VKLC

NF
.|
DF
Kinase FNIPK-D.AA FNIPK 191-245 19 7.7e-10 28.59 In-house 319-407 (425) Show / Hide 
Range on Protein: 191-245
Range on HMM: 319-407/425
Sequence Identity: 19% (17 aa)

FSLNIGYEDS---------------------IHLDMFNLGCVLIQMLGCD-C--TKDENID----------FLFSKIPNHLVEKFKKVI
....|.....                     ...|...|||..|.|.| . |  ..|..                ||| ||   .|  |
MPPEIKLQNGKCCRIAPEIRNQQKITSKGLSKKSDIWCLGCTMIEMVGGNLCHTENDIHGISFNNNNNKPNIWIPKIPDHLSNFCKNFI
Kinase FNIPK-D.AA S_TKc 33-267 17 1e-07 -63.88 SMART 1-231 (231) Show / Hide 
Range on Protein: 33-267
Range on HMM: 1-231/231
Sequence Identity: 17% (46 aa)

WEIITQLESNEQFTVYMSKKLKGPNFTNNRFGLCTVKKIKSQYFNENEILNHIKLRDNKYVLKYYGCGKDNNQDVYIYLEFIEY---SIPISKVKLIPND
.||. .. .    .||  .. |          .. .|.||     ..||  . |  . ... |.|..  |  ...|. .|...    .      ..| . 
YEILRKIGKGAFGKVYKCRHKK-------TGRIVAIKIIK--EHIRREIQILKK--HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDL----FDYIKKR

SSIDNFNNVSNTIIELVTCKLVESLNCIHKDNKIVHGNIKGENILLVNDESEYGFSVKFINFSLNIGYEDSI-----------------HLDMFNLGCVL
 .  .    .   .  ... ... |. .|.  .|.|  .| ||||| .        .| . | |   . ...                   |.  .||.|
GRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE-------HIKICDFGLARQL-TTFCGTPWYMAPEVLGYGKCKCDWWSCGCIL

IQMLGCDCTKDENIDFLFSKIPNHLVEKFKKVISQLLSKNINN----QILT---DIISNKIT
. ||      . ... .| ||     . .|  |...| |. ..    ..|.   || .    
YEMLCGYPPFP-QMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase FNIPK-D.AA Ciliate-C4 160-175 62 7.5e-05 11.09 In-house 158-173 (361) Show / Hide 
Range on Protein: 160-175
Range on HMM: 158-173/361
Sequence Identity: 62% (10 aa)

DNKIVHGNIKGENILL
.||.||..|| ||||.
QNKWVHCDIKPENILV
Kinase FNIPK-D.AA SAMK 163-179 52 0.000219 9.7 In-house 126-144 (295) Show / Hide 
Range on Protein: 163-179
Range on HMM: 126-144/295
Sequence Identity: 52% (10 aa)

IVHGNIKGENILLV--NDE
|.|..|.. ||||   |||
IIHRDINCDNILLDNENDE
Kinase FNIPK-D.AA VPS15 150-175 42 0.000311 10.7 In-house 107-132 (296) Show / Hide 
Range on Protein: 150-175
Range on HMM: 107-132/296
Sequence Identity: 42% (11 aa)

LVESLNCIHKDNKIVHGNIKGENILL
. . |...|| . ..|| || ||||.
TLCALEQCHKQGNVCHGDIKSENILV
Kinase FNIPK-D.AA MSK 149-181 33 0.000449 9.66 In-house 109-140 (277) Show / Hide 
Range on Protein: 149-181
Range on HMM: 109-140/277
Sequence Identity: 33% (11 aa)

KLVESLNCIHKDNKIVHGNIKGENILLVNDESE
.||  . ..|.   |.|. .| ||||. ..|..
ELVMAVDHMHQKG-IIHRDLKPENILFDDEEDN
FNIP FNIPK-D.AA FNIP 385-427 39 2.1e-12 47.04 Pfam 1-46 (46) Show / Hide 
Range on Protein: 385-427
Range on HMM: 1-46/46
Sequence Identity: 39% (18 aa)

FNQP-LTTDIIPKTVTILKL-QSFNQPIE-WGALPCSLVELSLASY
|||| |. ...|. ...|..  .||||||  . || || .|.. ..
FNQPFLEKGCLPNSIKHLIFGDNFNQPIEDINVLPNSLKHLEFGYC
FNIP FNIPK-D.AA FNIP 343-384 21 3.7e-09 35.62 Pfam 1-46 (46) Show / Hide 
Range on Protein: 343-384
Range on HMM: 1-46/46
Sequence Identity: 21% (10 aa)

FNQT-ILPGVIPTSVRTLKL-PSYNKTLT-QGSIPKGVRTLLL-SS
|||  . .|..| |.  |..  ..|. ..  ...|. . .| . ..
FNQPFLEKGCLPNSIKHLIFGDNFNQPIEDINVLPNSLKHLEFGYC
FNIP FNIPK-D.AA FNIP 301-342 26 1.3e-05 23.17 Pfam 1-46 (46) Show / Hide 
Range on Protein: 301-342
Range on HMM: 1-46/46
Sequence Identity: 26% (12 aa)

FNQP-ICKKTFTYGVYYLSL-SSFHRQLN-VGVIPESIHTLEL-AS
|||| . | ..  .. .| . ..| .... ..|.| |. .||.  .
FNQPFLEKGCLPNSIKHLIFGDNFNQPIEDINVLPNSLKHLEFGYC
FNIP FNIPK-D.AA FNIP 566-606 32 9.3e-11 41.23 Pfam 1-46 (46) Show / Hide 
Range on Protein: 566-606
Range on HMM: 1-46/46
Sequence Identity: 32% (15 aa)

FNHP-IRGESIPPSVIHLVF----NKLFSVIESIPSSVKYLDLGDE
||.| .  ...|.|..||.|    |. ...| ..|.|.|.| .|. 
FNQPFLEKGCLPNSIKHLIFGDNFNQPIEDINVLPNSLKHLEFGYC
FNIP FNIPK-D.AA FNIP 524-565 28 1.2e-05 23.25 Pfam 1-46 (46) Show / Hide 
Range on Protein: 524-565
Range on HMM: 1-46/46
Sequence Identity: 28% (13 aa)

FNQS-FETLPIPETVEYLKL-PMYNQPLT-PKLLPSGIKFLILP-S
|||. .|   .|. ...|..   .|||.. .  ||. .|.|..  .
FNQPFLEKGCLPNSIKHLIFGDNFNQPIEDINVLPNSLKHLEFGYC
FNIP FNIPK-D.AA FNIP 647-690 30 7.2e-07 27.6 Pfam 1-46 (46) Show / Hide 
Range on Protein: 647-690
Range on HMM: 1-46/46
Sequence Identity: 30% (14 aa)

FNIE-LLKNGISSNVTSLTLGSNFTNIES-LSNLPSSVTNLSFGIT
|| . | |. . .....|..|.||    .    ||.|.. |.||  
FNQPFLEKGCLPNSIKHLIFGDNFNQPIEDINVLPNSLKHLEFGYC